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Effect of Yeosin-dan on dystocia caused by abnormal expulsive fences in Primipara (여신단(如神丹) 첩부가 만출력 이상에 의한 난산을 해소한 임상증례보고)

  • Choi, Dae-Kyoung;Yoo, Sa-Hyun;Kim, Yang-Sik;Sohn, Yeong-Joo;Sohn, Nak-Won;Kim, Seong-Jun
    • The Journal of Korean Obstetrics and Gynecology
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    • v.18 no.4
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    • pp.219-229
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    • 2005
  • Objective : This clinical study investigated the effect of Yeosindan on dystocia caused by abnormal expulsive forces. Methods : Yeosindan was applied on the umbilicus of a primipara who had gone through latent phase for 15hrs and was almost expected to undergo C-sec by dystocia. It was sealed with an plaster. Yeosindan was removed immediately after the delivery. Results : 1. 90 minutes after Yeosindan had been applied on the umbilicus of the primipara, the active phase dilatation of uterus was started normally. 2. After 190 minutes from the Yeosindan application, the 2nd stage of labor was finished. 3. In this case, the delivery time, of which average is 344 minutes from the active phase to the second stage of labor, was reduced by 244 minutes. 4. So far, no abnormal condition has been detected in both the neonates and the primiparas.

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Clinical Validation of a Protein Biomarker Panel for Non-Small Cell Lung Cancer

  • Jung, Young Ju;Oh, In-Jae;Kim, Youndong;Jung, Jong Ha;Seok, Minkyoung;Lee, Woochang;Park, Cheol Kyu;Lim, Jung-Hwan;Kim, Young-Chul;Kim, Woo-Sung;Choi, Chang-Min
    • Journal of Korean Medical Science
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    • v.33 no.53
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    • pp.342.1-342.6
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    • 2018
  • We validated the diagnostic performance of a previously developed blood-based 7-protein biomarker panel, $AptoDetect^{TM}$-Lung (Aptamer Sciences Inc., Pohang, Korea) using modified aptamer-based proteomic technology for lung cancer detection. Non-small cell lung cancer (NSCLC), 200 patients and benign nodule controls, 200 participants were enrolled. In a high-risk population corresponding to ${\geq}55years$ of age and ${\geq}30pack-years$, the diagnostic performance was improved, showing 73.3% sensitivity and 90.5% specificity with an area under the curve of 0.88. $AptoDetect^{TM}$-Lung (Aptamer Sciences Inc.) offers the best validated performance to discriminate NSCLC from benign nodule controls in a high-risk population and could play a complementary role in lung cancer screening.

A Pilot Study of Herb Medication for Atopic Dermatitis (한약의 아토피 피부염 치료에 대한 예비 임상 연구)

  • Lim, Young-Kwon;Jung, Ji-A;Yun, Cheol-Sang;Hur, Kwang-Wook;Lee, Hun;Kim, Ho-Chyul;Kim, Young-Ran;Cho, Yun-Hi
    • The Journal of Pediatrics of Korean Medicine
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    • v.20 no.3
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    • pp.129-141
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    • 2006
  • Objectives : The purpose of this study is to determine clinical efficacy of herbal medicine by evaluating SCORAD Index and total level of ceramaides in the skin of 13 children with atopic dermatitis Methods : Subjects are divided into two groups : Group 1(non-differentiation children treated with Saenghyeoryunbueom) and group 2(differentiation children treated with either pyungwisan, onchungum or gamitongsungsan). We determine SCORAD Index and total level of ceramaides in the skin of 13 children with atopic dermatitis before and after taking each of herbal treatment for 12 weeks. Results : After herbal prescription for 12 weeks, A SCORAD index of both group 1 and group 2 was decreased. However, the total level of ceramides in group 1 and group 2 was not altered after 12 weeks. When the correlation between the alteration of SCORAD index and ceramides levels was determined, the SCORAD index in group 1 was inversely correlated with the total level of ceramides(r=-0.994, p=0.006) In contrast, the alteration of SCORAD index in group 2 was not correlated with ceramide levels. Conclusions : The clinical efficacy of Saenghyeoryunbueom for non-differentiation children with atopic dermatitis is paralleled with the increased level of ceramides in skin. The clinical efficacy of pyungwisan, onchungum or gamitongsungsan for differentiation children with atopic dermatitis is not correlated with ceramide level in skin.

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Survey on the Actual Conditions of Patients in Semyung University Attached Oriental Medical Hospital Night Clinic. (세명대학교 부속한방병원 야간 진료실 내원환자의 실태분석)

  • 민웅기;남창규
    • The Journal of Korean Medicine
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    • v.20 no.4
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    • pp.50-61
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    • 2000
  • This study on the visits of the oriental medical night clinic of patients, was made to be used as reference data by examining and analyzing statistically the many actual conditions of patients who had been visited in Semyung University Attached Oriental Medical Hospital during the period from April, 1998 to March, 1999. The purpose of this survey was to understand the characteristics of patients, to evaluate the roles of Night Clinic of oriental medical hospital, and contribute to the systemic and efficient management of night clinic service. The results obtained were as follows: I. Distribution of sex: male 53% (421 cases), female 47% (379 cases) 2. The age distribution of patients showed the highest in under ten, followed by the thirties and fifties, forties and twenties in order. 3. The monthly distribution of patients showed the highest in October 1998, followed by May 1998 and February 1999 in order. 4. The daily distribution of patients showed the highest in Sunday, followed by Saturday, Monday, Friday and Tuesday in order. 5. The regional distribution revealed the highest in Jecheon with 76% of all patients, followed by Danyang in order. 6. The distribution of arrival time showed the highest in 7:00 pm~0:00 am (27%), followed by 5:30 pm~7:00 pm (23%) in order. 7. The admission rate in patients was 17%. Among them direct visiting rate was 85%. Circulatory systemic disease was the highest. 8. The highest incidences by disease were of motor system with 48% (394cases), followed by diseases in circulatory system with 19% (l48cases). The majority of the patients 67% was connected with two diseases. 9. The chief complaint of pediatric diseases was febrile seizure with 64% (32cases), digestive disease was abdominal pain with 44% (90cases), circulatory diseases was motor disturbance with 43% (83cases), motor system disease was leg pain with 37% (l19cases), respiratory disease was fever with 46% ( 41 cases). 10. In the treatment method, a major portion of treatment methods was acupuncture treatment with 32% (373cases), followed by acupuncture & herbal medicine treatment with 23% (275cases). The most commonly used herbal medicines were Hangsapyunguisan(l6%) and Ojeoksan(l4%).

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Clinical Application of Gamitaeeumjowee-tang for Overweight or Obese Hypothyroidism Patients: A Retrospective Chart Review (과체중 또는 비만을 주소로 내원한 갑상선기능저하증 환자에 대한 가미태음조위탕의 임상적 활용: 후향적 차트 리뷰)

  • Min-Jeong Kim;Bo-Young Won;Hyo-Jin Kim;Ka-Hye Choi
    • Journal of Korean Medicine for Obesity Research
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    • v.23 no.2
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    • pp.78-85
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    • 2023
  • Objectives: Weight gain is one of the symptoms of hypothyroidism and it could deteriorate thyroid function. Our objectives are to evaluate weight changes and analyze adverse events in overweight and obese women with hypothyroidism who were prescribed Gamitaeeumjowee-tang. Methods: A retrospective chart review was conducted using medical records of patients with hypothyroidism, who had body mass indexes (BMI) above 23 and were prescribed Gamitaeeumjowee-tang for 12 weeks between August 2017 and November 2022. Reported adverse events (AEs) were assessed by severity, causality and system-organ classes. Results: Thirty patients were included (mean±standard deviation, age 46.10±9.94 years, weight 70.52±11.18 kg, BMI 28.30±3.80 kg/m2). The mean total weight loss of hypothyroidism patients was 5.45±2.77 kg, while the mean weight loss rate and mean BMI change were 7.66±3.41% and 2.18±1.07 kg/m2, respectively. Among evaluated causality of adverse events, 'Unlikely' was predominant (80.8%) and severity assessment showed most of the symptoms were mild (91.7%). Conclusions: Gamitaeeumjowee-tang could be an option for hypothyroidism patients, who are overweight or obese, to lose weight and no serious adverse events occurred. Further well-designed clinical studies are recommended.

Case Report of 20 Amenorrhea or Oligomenorrhea Patients due to Polycystic Ovarian Syndrome (다낭성난소증후군으로 인한 무월경, 희발월경 환자 20명의 증례 보고)

  • Lee, Ji-Hyun;Jung, So-Young
    • The Journal of Korean Obstetrics and Gynecology
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    • v.29 no.3
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    • pp.47-56
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    • 2016
  • Objectives: We evaluated the effect of Korean medical treatment in case of irregular menstruation (amenorrhea, oligomenorrhea) due to Polycystic ovarian syndrome (PCOS).Methods: 20 Amenorrhea or oligomenorrhea Patients with PCOS were treated with Korean medical treatment at least 3 months. We analyzed clinical data of 20 patients and checked effectiveness of treatment through the change of menstrual pattern.Results: After Korean medical treatment, Patients who complained menstrual irregularity due to PCOS were improved in menstrual condition. Among 14 amenorrhea patients, 12 patients (85.7%) started menstruation within 3 months. Among 6 Oligomenorrhea patients, 4 patients (66.7%) got better menstruation pattern than before.Conclusions: PCOS Patients who got Korean medical treatment showed better condition in menstruation pattern. Amenorrhea patients started menstruation without contraceptive pill and oligomenorrhea patients got better menstruation cycle.

Five Cases of Viral Warts Treated by Korean Medicine (사마귀 한방치험 5례 증례보고)

  • Lee, Jae-Hwi;Shim, Gye-Seon
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.28 no.2
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    • pp.121-129
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    • 2015
  • Objectives : The purpose of this study is to report the effect of Korean medical treatment for viral warts. Methods : All patients were treated by Bojungikki-tang gami. One of them was treated with only herbal medicine. The others were treated with herbal medicine, acupuncture, sweet bee venom acupuncture and moxibustion. To evaluate the results of these treatments, we observed condition of the patients and took the photos of lesions. Results : After Korean medical treatment, the viral warts of all patients remarkably disappeared and there have been no recurrence at all. Conclusions : We suggest that viral warts can be treated by Korean medical treatment.