Journal of Korean Medicine for Obesity Research (한방비만학회지)

The Society of Korean Medicine for obesity Research (한방비만학회)
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Clinical Application of Gamitaeeumjowee-tang for Overweight or Obese Hypothyroidism Patients: A Retrospective Chart Review

과체중 또는 비만을 주소로 내원한 갑상선기능저하증 환자에 대한 가미태음조위탕의 임상적 활용: 후향적 차트 리뷰

  • Min-Jeong Kim (Nubebe Korean Medical Clinic Hongdae Center) ;
  • Bo-Young Won (Nubebe Korean Medical Clinic Hongdae Center) ;
  • Hyo-Jin Kim (Nubebe Korean Medical Clinic Hongdae Center) ;
  • Ka-Hye Choi (Nubebe Korean Medical Clinic Hongdae Center)
  • Received : 2023.10.20
  • Accepted : 2023.11.29
  • Published : 2023.12.31
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Abstract

Objectives: Weight gain is one of the symptoms of hypothyroidism and it could deteriorate thyroid function. Our objectives are to evaluate weight changes and analyze adverse events in overweight and obese women with hypothyroidism who were prescribed Gamitaeeumjowee-tang. Methods: A retrospective chart review was conducted using medical records of patients with hypothyroidism, who had body mass indexes (BMI) above 23 and were prescribed Gamitaeeumjowee-tang for 12 weeks between August 2017 and November 2022. Reported adverse events (AEs) were assessed by severity, causality and system-organ classes. Results: Thirty patients were included (mean±standard deviation, age 46.10±9.94 years, weight 70.52±11.18 kg, BMI 28.30±3.80 kg/m2). The mean total weight loss of hypothyroidism patients was 5.45±2.77 kg, while the mean weight loss rate and mean BMI change were 7.66±3.41% and 2.18±1.07 kg/m2, respectively. Among evaluated causality of adverse events, 'Unlikely' was predominant (80.8%) and severity assessment showed most of the symptoms were mild (91.7%). Conclusions: Gamitaeeumjowee-tang could be an option for hypothyroidism patients, who are overweight or obese, to lose weight and no serious adverse events occurred. Further well-designed clinical studies are recommended.

Keywords

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