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HEALTH RISKS POSED BY MYCOTOXINS IN FOODS

  • Hsieh, D.P.H.
    • Toxicological Research
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    • v.6 no.2
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    • pp.159-166
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    • 1990
  • The ability of many toxigenic fungi to invade and develop in a wide variety of raw ingredients of human diet renders human exposure to mycotoxing very difficult to avoid. Most of the energy-rich commodities, such as cereal grains, oil seeds, tree nuts, and dehydrated fruits, are susceptible to mycotoxin contamination. Mycotoxins therefare have been recognized as an important class of hazardous substances in the human food chain. Although human exposure to mycotoxins is largely through ingestion, inhalation and skin contact may also be significant under conditions other than consumption of foods. Human ingestion of mycotoxins is due to consumption of contaminated dietary ingredients and the edible tissues and products of domestic animals that have been exposed to mycotoxins in moldy feed. Large scale acute human mycotoxicoses, such as ergotism in France, alimentary toxic aleukia in Russia, yellow rice syndrome in Japan, endemic nephropathy in Balkan countries, and acute aflatoxin poisonings in India and Taiwan, have been well documented, indicating that mycotoxicosis is a global problem. In some incidents, hundreds of victims were killed and many more became seriously ill. The mycotoxins that have been implicated in the etiology of these human diseases include aflatoxins, citreoviridin, cyclopiazonic acid, ergot alkaloids, moniliformin, ochratoxin A, trichothecenes, tenuazonic acid, and zearalenone. Among these, aflatoxins have been also implicated in the etiology of human primary liver cancer in those high-incidence countries in Africa and southeast Asia. It is well recognized that cause-effect relationship between mycotoxins and human diseases is very difficult to establish, especially for the cancer connection. Careful risk assessment must be performed to determine whether a mycotoxin indeed warrants costly regulatory actions.

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A Study on Cybersecurity Policy in the Context of International Security (국제협력을 통한 사이버안보 강화방안 연구)

  • Kim, So Jeong;Park, Sangdon
    • Convergence Security Journal
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    • v.13 no.6
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    • pp.51-59
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    • 2013
  • Cyberspace, based on the dramatic development of information and communications technology, has brought enormous benefits to mankind. However, concerns over cyber terrorism and cyber attack are becoming serious. It is time to expand the global dialogue on international security issues in cyberspace. It is imperative to have a common understanding that cyberspace, the infrastructure for prosperity, should not be utilized as a space to create conflicts among states, and that all states agree to build confidence and peace in cyberspace. For this purpose, there are 3 tracks of international cooperations: 1)international cooperation such as UN and Conference on Cyberspace, 2)regional cooperations such as ARF and OSCE. 3)bilateral cooperations such US-Russia Cybersecurity Agreement, US-China presidential level dialogue. This paper will analyze the 1st track of international cooperations of UN and Conference on Cyberspace. With this, Korean government can prepare the forthcoming GGE activities and make our own strategy to deal with the global norms of good behaviour in cyberspace.

Development of Method to Predict Source Region of Swell-Like High Waves in the East Sea (동해안 너울성 고파의 발생역 추정법 개발)

  • Ahn, Suk Jin;Lee, Changhoon;Kim, Shin Woong;Jeong, Weon-Mu
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.28 no.4
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    • pp.212-221
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    • 2016
  • In this study, characteristics of swell-like high waves in the East Sea were analyzed using observed wave data and predicted meteorological data from the National Oceanic and Atmospheric Administration (NOAA). And, the wave prediction system using the data from the NOAA has been established. Furthermore, the applicability of the system has been verified by comparing the predicted results with the corresponding observed data. For some case, there were two times of wave height increase and the second increase occurred in a calm weather condition on the coast which might cause casualties. The direction of wave energy propagation was estimated from observed wave data in February, 2008. Through comparison between the direction of wave energy propagation and the meteorological data, it turns out that the second increase of waves is originated from the seas between Russia and Japan which is far from the East Sea.

Anticorrosive Monitoring and Complex Diagnostics of Corrosion-Technical Condition of Main Oil Pipelines in Russia

  • Kosterina, M.;Artemeva, S.;Komarov, M.;Vjunitsky, I.;Pritula, V.
    • Corrosion Science and Technology
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    • v.7 no.4
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    • pp.208-211
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    • 2008
  • Safety operation of main pipelines is primarily provided by anticorrosive monitoring. Anticorrosive monitoring of oil pipeline transportation objects is based on results of complex corrosion inspections, analysis of basic data including design data, definition of a corrosion residual rate and diagnostic of general equipment's technical condition. All the abovementioned arrangements are regulated by normative documents. For diagnostics of corrosion-technical condition of oil pipeline transportation objects one presently uses different methods such as in-line inspection using devices with ultrasonic, magnetic or another detector, acoustic-emission diagnostics, electrometric survey, general external corrosion diagnostics and cameral processing of obtained data. Results of a complex of diagnostics give a possibility: $\cdot$ to arrange a pipeline's sectors according to a degree of corrosion danger; $\cdot$ to check up true condition of pipeline's metal; $\cdot$ to estimate technical condition and working ability of a system of anticorrosive protection. However such a control of corrosion technical condition of a main pipeline creates the appearance of estimation of a true degree of protection of an object if values of protective potential with resistive component are taken into consideration only. So in addition to corrosive technical diagnostics one must define a true residual corrosion rate taking into account protective action of electrochemical protection and true protection of a pipeline one must at times. Realized anticorrosive monitoring enables to take a reasonable decision about further operation of objects according to objects' residual life, variation of operation parameters, repair and dismantlement of objects.

Thermal-hydraulic Analysis of Operator Action Time on Coping Strategy of LUHS Event for OPR1000 (OPR1000형 원전의 최종열제거원 상실사고 대처전략 및 운전원 조치 시간에 따른 열수력 거동 분석)

  • Song, Jun Kyu
    • Journal of the Korean Society of Safety
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    • v.35 no.5
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    • pp.121-127
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    • 2020
  • Since the Fukushima nuclear accident in 2011, the public were concerned about the safety of Nuclear Power Plants (NPPs) in extreme natural disaster situations, such as earthquakes, flooding, heavy rain and tsunami, have been increasing around the world. Accordingly, the Stress Test was conducted in Europe, Japan, Russia, and other countries by reassessing the safety and response capabilities of NPPs in extreme natural disaster situations that exceed the design basis. The extreme natural disaster can put the NPPs in beyond-design-basis conditions such as the loss of the power system and the ultimate heat sink. The behaviors and capabilities of NPPs with losing their essential safety functions should be measured to find and supplement weak areas in hardware, procedures and coping strategies. The Loss of Ultimate Heat Sink (LUHS) accident assumes impairment of the essential service water system accompanying the failure of the component cooling water system. In such conditions, residual heat removal and cooling of safety-relevant components are not possible for a long period of time. It is therefore very important to establish coping strategies considering all available equipment to mitigate the consequence of the LUHS accident and keep the NPPs safe. In this study, thermal hydraulic behavior of the LUHS event was analyzed using RELAP5/Mod3.3 code. We also performed the sensitivity analysis to identify the effects of the operator recovery actions and operation strategy for charging pumps on the results of the LUHS accident.

Cytotype distribution and ecology of Allium thunbergii (= A. sacculiferum) with a special reference to South Korean populations

  • SHUKHERDORJ, Baasanmunkh;JANG, Ju Eun;DUCHOSLAV, Martin;CHOI, Hyeok Jae
    • Korean Journal of Plant Taxonomy
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    • v.48 no.4
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    • pp.278-288
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    • 2018
  • Polyploidization plays an important role in generating the current high diversity of plants. Studies of the distributional patterns of diploid and derivative polyploid races have provided important insights into the evolutionary process and cryptic speciation by polyploidization within and between closely related taxa defined on the basis of their morphology. Allium thunbergii and A. sacculiferum, occurring throughout eastern Russia, eastern China, Korea, and Japan, are examples of closely related species with unsolved taxonomic relationships. A total of 97 and 65 individuals from 26 and 13 populations of A. thunbergii (including var. thunbergii, var. deltoids, and var. teretifolium) and A. sacculiferum, respectively, were studied to determine their ploidy. The geographic structure and habitat differentiation of the cytotypes were also analyzed. The main cytotype of A. thunbergii was diploid (92.3% in total; the rest were tetraploids). In contrast, the majority of A. sacculiferum plants were tetraploids (69.2% of the total; the rest were diploids). No populations of the studied taxa harbored both cytotypes. Allium thunbergii was more often found at higher elevations than A. sacculiferum, and it tended to occur more frequently on rocky slopes and below forests in mountainous areas. On the other hand, A. sacculiferum occurred at forest margins and in lowland pastures. The cytotypes differed with respect to the elevation; diploids were found more frequently at higher elevations than tetraploids. The results of this study and additional biosystematics data indicate that the morphological characteristics of A. thunbergii and A. sacculiferum may be influenced by polyploidization and by their adaptation to various habitat conditions and that A. thunbergii and A. sacculiferum do not clearly fulfill the requirements of any species concept. Consequently, we propose that A. sacculiferum be considered as an additional synonym of A. thunbergii. Additionally, Allium thunbergii var. deltoides is unified into A. thunbergii var. thunbergii.

A Study on the Status of Korean Collection at the University of Hawaii Focus on the Special Korean Collection (하와이대학교 한국 컬렉션 현황 연구 - '스페셜 코리안 컬렉션(Special Korean Collecton)'을 중심으로 -)

  • Yeun, Keum-Sun
    • Journal of Korean Library and Information Science Society
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    • v.49 no.4
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    • pp.329-349
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    • 2018
  • This study focused on the 'Special Korean Collection' at the University of Hawaii's Hamilton Library, to examine the actual construction of Korean academic materials. The collection includes rare books by Marshall Pihl and Korean academic materials collected by 'the Korea Center'. And the following points were reviewed. First, what is the actual status of Korean academic data? Second, what is the field of study and what is the value of the material? Furthermore, this research sought to shed light on the Korean studies of early Korean emigrants. This includes not only the Americas but also Northeast Asia, Russia and Central Asia. There is a lack of comprehensive review of these materials at present. As a result, despite they are important research material, it is assumed that researchers have failed to grasp the academic, literary, cultural and artistic data of contemporary Korean emigrants. So the study also provided an understanding and future direction of the Korean collection.

The Characteristics of South Korea's New Northern Policy and Cooperation with Eurasia Countries' Initiatives Focused on China, Mongolia and Russia (인간의 불안 심리를 반영한 장신구 디자인 연구)

  • Kim, Sung-Ryun
    • Journal of Digital Convergence
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    • v.17 no.8
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    • pp.367-372
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    • 2019
  • Today we are living in a capitalist society where competition is prevalent and natural phenomenon. We compare ourselves to others in overheated competition, concerning the views of others. We comfort many assessments of other that causes in anxiety and controls our behaviors unconsciously. We hypothesize that such anxiety originate from eyes of others, and studied anxiety in general and anxiety about other's gaze. Specifically, the study of ornament was conducted with emphasis on the eye and intense colors from the anxiety of competition in famous movie "Black Swan". We used color in the art work as a tool to reflect the authors inner phycology, and tried to deliver author's emotion and message simultaneously. Moreover, we tried to share and express the anxiety of modern people through the from of "eye".

Anti-diabetic effects of blue honeyberry on high-fed-diet-induced type II diabetic mouse

  • Sharma, Anshul;Kim, Joo Wan;Ku, Sae-Kwang;Choi, Jae-Suk;Lee, Hae-Jeung
    • Nutrition Research and Practice
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    • v.13 no.5
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    • pp.367-376
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    • 2019
  • BACKGROUND/OBJECTIVE: The blue honeysuckle berry (Lonicera caerulea var. edulis L.) is a small deciduous shrub belonging to the Caprifoliaceae family that is native to Russia, China, Japan, and Korea. The berry of this shrub is edible, sweet and juicy and is commonly known as the blue honeyberry (BHB). This study examined the anti-diabetic potential of BHB on high-fat-diet-induced mild diabetic mice. The hypoglycemic, and nephroprotective effects of the 12-week oral administration of blue honeyberry extract were analyzed. MATERIALS/METHODS: The hypoglycemic effects were based on the observed changes in insulin, blood glucose, and glycated hemoglobin (HbA1c). Furthermore, the changes in the weight of the pancreas, including its histopathology and immunohistochemical investigation were also performed. Moreover, the nephroprotective effects were analyzed by observing the changes in kidney weight, its histopathology, blood urea nitrogen (BUN), and serum creatinine levels. RESULTS: The results showed that the high-fat diet (HFD)-induced control mice showed a noticeable increase in blood glucose, insulin, HbA1c, BUN, and creatinine levels. Furthermore, growth was observed in lipid droplet deposition related to the degenerative lesions in the vacuolated renal tubules with the evident enlargement and hyperplasia of the pancreatic islets. In addition, in the endocrine pancreas, there was an increase in the insulin-and glucagon-producing cells, as well as in the insulin/glucagon cell ratios. On the other hand, compared to the HFD-treated mice group, all these diabetic and related complications were ameliorated significantly in a dose-dependent manner after 84 days of the continuous oral administration of BHBe at 400, 200 and 100 mg/kg, and a dramatic resettlement in the hepatic glucose-regulating enzyme activities was observed. CONCLUSIONS: By assessing the key parameters for T2DM, the present study showed that the BHBe could act as a potential herbal agent to cure diabetes (type II) and associated ailments in HFD-induced mice.

Differences in Patient Experience by Arrangement Type of Medical Tourism Facilitators (외국인환자 유치업자 유형별 환자경험의 차이)

  • Cho, Heeran J.;Jin, Ki Nam
    • Korea Journal of Hospital Management
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    • v.26 no.2
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    • pp.27-42
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    • 2021
  • This study investigated the differences in patient experience by arrangement type of medical tourism facilitators(MTF) from the pre-visit to visit stages. Specifically, patient experiences from each stage with different service providers (MTFs and medical institutions) were measured: provision of information and respect for patient preferences as pre-visit experiences with the facilitators, communication and concierge services as visit experiences with the facilitators, and medical services as medical institution experiences. The scale to measure foreign patients' experiences was modified from the 'Picker in-patient questionnaire(PPE)' and the 'Picker patient experience questionnaire(PPE-15)'. Quantitative data were collected by conducting a self-administered questionnaire on 173 patients from China, Russia, Mongolia, and Kazakhstan. Qualitative data were collected by conducting in-depth interviews with 9 patients and 9 service providers. The data were collected between January and October in 2019. Quantitative data was analyzed by SPSS 25 for Chi-squared test and ANOVA, and qualitative data were analyzed based on keywords. The main results are as follows. When foreign patients used only overseas MTFs, they had a relatively positive patient experience in respect of receiving pre-visit information(F=7.47, p<.01) and respect for patient preferences(F=3.11, p<.05). Looking at both domestic and overseas facilitators during the visit, the patient experience was relatively negative for communication(F=3.75, p<.05). Regarding medical institutions, patients had a relatively negative patient experience with regards to medical services when they used both domestic and overseas facilitators(F=6.49, p<.01). The implications of this study are as follows. Patients should have a seamless and high-quality experience regardless of the facilitator arrangement type. This can be prepared through service standardization for the service providers. It would be also necessary to consider each other's features and problems at the institutional level and to improve service coordination by having service providers periodically communicate with each other.