• Title/Summary/Keyword: kit evaluation

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Development of a Remotely Operated Aerial Robot-kit based on the Balloon (풍선기반 원격조종 공중로봇키트 개발)

  • Kim, Hyun-Sik
    • The Journal of Korea Robotics Society
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    • v.7 no.3
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    • pp.216-221
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    • 2012
  • Recently, although the need of marine robots being raised in extreme areas, the basis is very deficient. Fortunately, as the robot competition is vitalizing and the need of the robot education is increasing, it is desirable to establish the basis of the R&D and industrialization of marine robots and to train professionals through the development and diffusion of marine robot kits. However, in conventional case, there is no remotely operated aerial robot-kit based on the balloon for the marine robot competition, which has the abilities of the airborne locomotion and obstacle avoidance. To solve this problem, an aerial robot-kit which has the abilities of the airborne locomotion and remote control, is developed. To verify the performance of the developed kit, test and evaluation such as surge, yaw and pitch is performed. The test and evaluation results show that the possibility of the real applications of the developed kit.

Evaluation of Rapid Immunochromatographic Assay Kit for HBsAg-Screening Using Whole Blood

  • Shin, Hyeong-Soon;Heo, Tae-Ryeon
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.5 no.5
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    • pp.362-365
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    • 2000
  • A rapid immunochromatographic assay kit using whole blood to screen hepatitis B surface antigen was developed and evaluated by using sera from 240 patients. The reference diagnosis was based on the results obtained with GENEDIA Anti-HBs Rapid kit which is very similar to the above kit except for the use of serum. The test demonstrated a good correlation with the reference immunochromatographic assay kit, that is, the sensitivity and the specificity of the kit was 100%, respectively. The rapid test kit using whole blood should be more convenient and useful for the diagnosis of hepatitis B virus because the kit does not need machines and time to prepare serum. In addition, this kit is safe from inadvertent infection during sample treatment because the blood is sterilized with hydrogen peroxide, eliminates the procedure required to prepare serum and reduces the possibility of exposure to infectious agents.

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A Comparative Evaluation of Three Rapid Tests of Syphilis and ARCHITECT Syphilis TP

  • Kim, Won-Shik
    • Korean Journal of Clinical Laboratory Science
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    • v.43 no.1
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    • pp.1-5
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    • 2011
  • The infection rate of syphilis is still increasing in the world especially in developing countries and the infection is often seen in large amounts of clinical specimens. For the diagnosis of this disease, Rapid Plasma Reagin (RPR)/Venereal Disease Research Laboratory (VDRL) has still been used as one of major primary methods to diagnose syphilis even though the test readings are somewhat subjective with high false positive rates. Recently, the automatic ARCHITECT Syphilis TP, which is based on the detection of the TP-specific antibodies, has been introduced in many laboratories. Therefore, the clinical assessment of the method is needed to provide primary diagnosis of syphilis at the moment. We evaluated 3 different manual rapid kits and ARCHITECT Syphilis TP comparing with RPR/FTA-ABS and analysed their diagnostic properties. From February 2006 to April 2008, 203 positive and 250 negative specimens, obtained from Chungbuk National University Hospital were used for the evaluation. In the evaluation between manual rapid kits, their specificities were as high as 99.2 ~ 99.6% while their sensitivities were observed with little differences; 98.0% (199/203) for Kit A, 96.6% (196/203) for Kit B, and 97.4% (197/203) for Kit S. In the case of ARCHITECT Syphilis TP test, it showed 100% specificity (250/250) and 98.5% sensitivity (249/250). Kappa values comparing with RPR/FTA-ABS were 0.978 for Kit A, 0.964 for Kit B and Kit S, and 0.987 for ARCHITECT Syphilis TP. From our evaluation, we found out that manual rapid tests and ARCHITECT Syphilis TP have very good clinical accuracies and high kappa agreements with RPR/FTA-ABS. Due to its automation and quick simultaneous diagnosis with another serological markers, we suggest that the ARCHITECT Syphilis TP is one of best suitable method for the primary diagnosis of syphilis and that it might be able to replace RPR method in the laboratories.

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Subchronic Oral Dose Toxicity of Freeze-dried Powder of Allomyrina dichotoma Larvae

  • Noh, Jung-Ho;Yun, Eun-Young;Park, Heejin;Jung, Kyung-Jin;Hwang, Jae Sam;Jeong, Eun Ju;Moon, Kyoung-Sik
    • Toxicological Research
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    • v.31 no.1
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    • pp.69-75
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    • 2015
  • The objective of this study was to investigate the toxicological information of freeze-dried powder from Allomyrina dichotoma (A. dichotoma) larvae as a food ingredient. The powder, suspended in distilled water, was administered once daily by oral gavage to four groups of Sprague-Dawley (SD) rats at dose levels of 0 (vehicle control), 250, 850, and 2500 mg/kg/day. After 13 wks of repeated administration, the standard toxicological parameters such as mortality, clinical signs, body weight, food consumption, ophthalmologic examination, clinical pathology, organ weights and macro/microscopic examination were applied for assessment of general toxicity. In addition, serum IgE and histamine levels were determined to evaluate allergenicity. The freeze-dried powder from A. dichotoma larvae did not produce treatment-related changes or findings in any toxicological parameters in either sex of any dosed groups except for slight increases in serum histamine levels at 2500 mg/kg/day. The changes were considered not to be adverse since the magnitude was minimal. In conclusion, the NOAEL (No Observed Adverse Effect Level) of the freeze-dried powder from A. dichotoma larvae was determined to be 2500 mg/kg/day or more in both sexes of SD rats and it is considered a candidate to be edible material.

Basic Research on the Development of Kit and Program for Fashion Psychotherapy

  • Yu, Ji-Hun;Song, So-Won;Son, Hee-Jung
    • The International Journal of Costume Culture
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    • v.13 no.2
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    • pp.67-81
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    • 2010
  • This study is a basic research to develop kit and program for fashion psychotherapy, a new genre of therapy. Symptom checklist, self-esteem evaluation, interpersonal relationship problem evaluation and fashion preference evaluation were conducted on 159 college students in Seoul. The results were analyzed with t-test and one-way ANOVA. The result showed that first, warm color preference was significantly high in interpersonal problem among psychological problems. Second, smooth material preference was significantly high in paranoia among psychological problems. Third, differences in design preferences by psychological problems were not significant. Fourth, differences in design preferences between abnormal range and normal range of psychological problems were significant in line shape, with depression abnormal group showing significantly high straight line preference. Additionally, complex shape preference was significant in complexity in somatization and phobia abnormal groups. This study can be utilized in kit development for a new field, fashion psychotherapy. This study is significant as practical basic data in constructing fashion psychotherapy program.

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Development of a 3-axis fine positioning stage : Part 2. Experiments and performance evaluation (초정밀 3축 이송 스테이지의 개발 :2. 동특성 실험 및 성능 평가)

  • Kang, Joong-Ok;Kim, Man-Dal;Baek, Seok;Han, Chang-Soo;Hong, Sung-Wook
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2003.06a
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    • pp.1207-1210
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    • 2003
  • This paper deals with experiments for dynamic characteristics and performance evaluation of the 3-axis fine positioning stage developed in [1]. The features of the developed fine positioning stage are the long stroke due to the magnetically preloaded PZT actuators, the minimum motion crosstalk due to the use of a ball contact mechanism and the compact design. The dynamic characteristics of the actuator and the stage are tested with the preload changed in order to validate the actuator and the stage design. Performance evaluation is also made for the PZT actuators as well as the stage positioning accuracy. Experimental results show that the developed stage is accurate enough to be used for nanometer positioning.

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Clinical evaluation of a rapid diagnostic test kit for detection of canine coronavirus

  • Yoon, Seung-Jae;Seo, Kyoung-Won;Song, Kun-Ho
    • Korean Journal of Veterinary Research
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    • v.58 no.1
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    • pp.27-31
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    • 2018
  • Canine coronavirus is a single-stranded RNA virus that causes enteritis in dogs of any age. Coronaviral enteritis is seldom definitively diagnosed, since it is usually much less severe than many other types of enteritis and is self-limiting. Conventional diagnostics for the canine coronaviral enteritis such as polymerase chain reaction (PCR), virus isolation, and electron microscopic examination are inappropriate for small animal clinics due to the complicated experimental processes involved. Therefore, a commercially available lateral flow test kit based on chromatographic immunoassay techniques was tested to evaluate its performance as a first-line diagnostic test kit that could be used in clinics. The coronavirus antigen test kit detected canine coronavirus-infected dogs with 93.1% sensitivity and 97.5% specificity. The detection limit of the test kit was between $1.97{\times}10^4/mL$ and $9.85{\times}10^3/mL$ for samples with a 2-fold serial dilution from $1.25{\times}10^6\;TCID_{50}$ ($TCID_{50}$, 50% tissue culture infectious dose). Additionally, the test kit had no cross-reactivity with canine parvovirus, distemper virus, or Escherichia coli. Overall, the commercially available test kit showed good diagnostic performance in a clinical setting, with results similar to those from PCR, confirming their potential for convenient and accurate use in small animal clinics.

Forensic Evaluation of Prostate-Specific-Antigen (PSA) Rapid Test Kit for Identification of Human Semen (전립선특이항원검사 Kit에 의한 정액의 신속 검출법)

  • Lim, Chae-Won;Lee, Jong-Hoon;Kim, Hyung-Lak
    • Korean Journal of Clinical Laboratory Science
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    • v.41 no.2
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    • pp.76-82
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    • 2009
  • It would be one of the most important tests that determination of semen in crime scene as a matter of significant evidences. Recently, it has been developed for the identification of semen in forensic specimens which was used simply, easily and reproductively. In this study, Prostate-Specific-Antigen (PSA) Rapid Test kit was evaluated for the forensic identification of semen and compared with one step semen inspection forensic rapid test kit. The sensitivity and specificity of the rapid PSA kit were examined in addition to the stability of PSA. The positive band of rapid PSA kit shown even with 1,000,000-fold diluted semen, which was at least 100 timed higher than qualitative one step semen inspection forensic rapid test kit. PSA was detected in urine from normal male adult, however, it was not detected in urine from young boys and female body fluids. It was shown that PSA was very stable to resist boiling for 20 minutes and the effect of bacteria. In crime scene investigation, rapid PSA kit is expected to help to identify semen easily in the evidences.

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Assay of Human Chorionic Gonadotropin in Urine of Athletes and Evaluation of Assay Kit Performance (운동선수들의 뇨 중 Human Chorionic Gonadotropin 분석 및 분석킷트 평가)

  • 최명자;이정란;김명수
    • Biomolecules & Therapeutics
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    • v.10 no.3
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    • pp.186-192
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    • 2002
  • Special attention has been paid to human chorionic gonadotropin (hCG) for athlete doping control because it stimulates the endogenous production of testosterone and epitestosterone without increasing the T/E ratio which is a doping indicator for the exogenous administration of testosterone. Even though the IOC banned the use of hCG, a detection method has not been decided upon since there are a variety of immunoassay kits available on the market. We evaluated three kits in terms of their performance characteristics. The assay value of the control sample varied depending on the kit, resulting in 198 mIU/ml for the MAIA kit, 172mIU/ml for the IRMA kit, and 143 mIU/ml for the MEIA kit. Considering the IOC inter-lab distribution of results(55-312 mIU/ml) using 27 different kits and the mean value (178$\pm$56 mIU/ml), all three kits are within the range of -15.8% - +5.6% of the mean value, which proves them useful for the hCG assay. The MEIA kit resulted in lower hCG values because it detects only intact hCG molecules, in contrast to the other two kits which detect intact hCG and -hCG together. However, it is suitable for screening purposes because of its advantage of being an automated system. When 123 urine samples of athletes were analyzed in 22 batches using this system, the variation of control values fell within $\pm$ 10% of the mean values, and an specimens tested negative with hCG values less than the detection limit of 2 mIU/ml.