• Journal of Korean Society of Coastal and Ocean Engineers
• /
• v.17 no.2
• /
• pp.86-97
• /
• 2005

Accurate estimation of the wave-induced pore water pressure in the seabed is key factor in studying the stability of the seabed in the vicinity of coastal structure. Most of the existing numerical models for wave structure seabed interaction have been linked through applying hybrid numerical technique which is analysis method separating the wave field and seabed regime. Therefore, it is necessary to develope a numerical model f3r simulating accurately wave$\cdot$structure$\cdot$ seabed interaction under wave loadings by the single domain approach for wave field and seabed regime together. In this study, direct numerical simulation is newly proposed. In this model, modeled fluid drag has been used to detect the hydraulic properties according to the varied geometrical shape inside the porous media by considering the turbulence resistance as well as laminar resistance. Contrary to hybrid numerical technique, direct numerical simulation avoids the explicit formulation of the boundary conditions at the fluid/porous media interface. A good agreement has been obtained by the comparison between existed experimental results by hydraulic model test and direct numerical simulation results far wave $\cdot$structure$\cdot$seabed interaction. Therefore, the newly proposed numerical model is a powerful tool for estimating the nonlinear dynamic responses among a structure, its seabed foundation and water waves.

• Journal of Life Science
• /
• v.27 no.1
• /
• pp.38-43
• /
• 2017

Glycosyl aesculin, a potent anti-inflammatory agent, was synthesized by transglycosylation reaction, catalyzed by Thermotoga neapolitana ${\beta}-glucosidase$, with aesculin as an acceptor. The key reaction parameters were optimized using response-surface methodology (RSM) and $2{\mu}g$ of the enzyme. As shown by a statistical analysis, a second-order polynomial model fitted well to the data (p<0.05). The response surface curve for the interaction between aesculin and other parameters revealed that the aesculin concentration and reaction time were the primary factors that affected the yield of glycosyl aesculin. Among the tested factors, the optimum values for glycosyl aesculin production were as follows: aesculin concentration of 9.5 g/l, temperature of $84^{\circ}C$, reaction time of 81 min, and pH of 8.2. Under these conditions, 61.7% of glycosyl aesculin was obtained, with a predicted yield of 5.86 g/l. The maximum amount of glycosyl aesculin was 6.02 g/l. Good agreement between the predicted and experimental results confirmed the validity of the RSM. The optimization of reaction conditions by RSM resulted in a 1.6-fold increase in the production of glycosyl aesculin as compared to the yield before optimization. These results indicate that RSM can be effectively used for process optimization in the synthesis of a variety of biologically active glycosides using bacterial glycosidases.

• Korean Journal of Cognitive Science
• /
• v.17 no.4
• /
• pp.303-321
• /
• 2006

According to Harris'(1966) distributional hypothesis, understanding the meaning of a word is thought to be dependent on its context. Under this hypothesis about human language ability, this paper proposes a computational model for native speaker's language processing mechanism concerning word sense disambiguation, based on two sets of experiments. Among the three computational models discussed in this paper, namely, the logic model, the probabilistic model, and the probabilistic inference model, the experiment shows that the logic model is first applied fer semantic disambiguation of the key word. Nexr, if the logic model fails to apply, then the probabilistic model becomes most relevant. The three models were also compared with the test results in terms of Pearson correlation coefficient value. It turns out that the logic model best explains the human decision behaviour on the ambiguous words, and the probabilistic inference model tomes next. The experiment consists of two pans; one involves 30 sentences extracted from 1 million graphic-word corpus, and the result shows the agreement rate anong native speakers is at 98% in terms of word sense disambiguation. The other pm of the experiment, which was designed to exclude the logic model effect, is composed of 50 cleft sentences.

• The Korean Journal of Physiology
• /
• v.4 no.2
• /
• pp.37-44
• /
• 1970

Human body volumes were calculated from the measurments of body height and body weight. Equations Suited to express the relations of height, weight, and surface area to show the body volume were derived from the body volume measurements by means of underwater. weighing method. Underwater body weights were corrected for the residual volume of long obtained by the Rahn's three breath method. Underwater weighing was performed on 173 male subjects aged between 13 and 51 years. Subjects were divided into 4 age groups, namely, 13-16 years group of 47 subjects, 16-19 years group of 46 subjects, adult group aged between 22 and 38 years comprising 45 subjects, and middle-aged group (40-51 years) of 35 subjects. The group division was made on .the basis of physical growth and development. The following results were obtained. 1. Body height (H, cm), body weight (W, kg), body surface area $S,\; m^{2})$, and body volume (V, liter.) interrelated closely. V/S showed a high correlation with W/H and the coefficient of correlation was r=0.97 irrespective of age group differences of the subjects. The coefficients of correlation between V/S and W/H in the total mate subjects as a single group was r=1.983. Subsequently the following regression equation was obtained. V = S X (54.84 W/H + 14.08) The agreement of body volume values obtained by the calculation and underwater weighing in the total subject group was better than that of the separate age group division. 2. The calculated values of body volume were: 40.4 l (euiqvalent to the body density value of 1.0562 kg/1) in 13-16 years group; 52.0 l (equivalent to density value of 1.0723 kg/l) in 16-19 years group; 55.3 l (equivalent to density value of 1.0570 kg/l) In the adult group; and 54. 0 l (equivalent to density value of 1.074 kg/l) in the middle-age group. The mean deviation of calculated from the measured volume value ranged between ${\pm}0.55$ and ${\pm}0.81$ liters. 3. The correlation between V/S and mean skinfold thickness of 4 sites (arm, back, iliac and chest) was high, namely, the coefficient of correlation was r=0.656. The coefficients of correlation between V./S and the $R\"{o}hrer$ index ranged between r=0.668 and r=0.810 affected by the difference in group age of the subject. The body volume (V) alone correlated poorly than V/S with mean skinfold thickness (r=0.606) and the $R\"{o}hrer$ index (r ranged between 0.274 and 0.588).

• Korean journal of communication and information
• /
• v.34
• /
• pp.34-62
• /
• 2006

The World Summit on the Information Society (WSIS) was held in two phases. The first phase took place in Geneva, December 2003, and the second phase took place in Tunis, November 2005. The objective of the WSIS was to establish the foundations for an Information Society for all, reflecting all the different interests at stake. In relation to, this article explore the vision and paradigm of WSIS. For this, this article review the historical context of International information order and International agreements, and examine the issues of WSIS. As a result, I recognize, It is valuable that the process of WSIS for Global governance was held among governments and other stakeholders, i.e. the private sector, civil society and international organization. In addition, developing countries's voice are deeply reflected on the WSIS. It is noticeable that ITU played key role as coordinator. However, we are anxious that WSIS's vision for Information society have a bias toward Technology determinism. Eventually, this article argue that WSIS discourse is the lack of any serious and critical structural analysis of the politico-economic context.

• Asian Pacific Journal of Cancer Prevention
• /
• v.15 no.21
• /
• pp.9417-9421
• /
• 2014

Background: Esophageal cancer is one of the most frequently occurring malignancies and the seventh leading cause of cancer-related deaths in the world. The esophageal squamous cell carcinoma (ESCC) is the most common histological type of esophageal cancer worldwide. Materials and Methods: Our goal in this study was to detect phospholipase A2 Group IIA (PLA2G2A) and cyclooxygenase-2 (COX-2) immuno-expression in ESCC in a high-risk population in China. Results: Positive expression of PLA2G2A protein was observed in 57.2% (166/290) of the cases, while COX-2 was found in 257 of 290 samples (88.6%), both PLA2G2A and COX-2 being expressed in 153 cases (52.8%), with a significant agreement (Kappa=0.091, p=0.031).Overexpression of PLA2G2A was significantly correlated with the depth of invasion (p=0.001). Co-expression of PLA2G2A and COX-2 not only significantly correlated with the depth of invasion (p=0.004) but also with TNM stage (p=0.04). Conclusions: Our results showed that in patients with ESCC, PLA2G2A overexpression and PLA2G2A co-expression with COX-2 is significantly correlated with advanced stage. The biological role and pathophysiologic regulation of PLA2G2A and COX-2 overexpression in ESCC deserve further investigation.

• Proceedings of the Korean Institute Of Construction Engineering and Management
• /
• 2004.11a
• /
• pp.51-58
• /
• 2004

The input-oriented project promotion system private participation in infrastructure projects currently in use in Korea has encountered difficulties in securing the primary benefits of private sector creativity problem solving and inflow of private capital. As such, the performance (or output)-oriented procurement process implemented in England and other developed countries should be evaluated for introduction. In Korea, private participation projects are currently identified as either solicited or unsolicited projects, each with different promotional procedures, the problem with these procedures is that competition is not pre-activated, the private sectors creativity is under utilized, and the rationality of project evaluations is inconsistent. Korea should, in order to raise the level of private sector creativity and efficiency, go beyond the currently applied Input Specification project promotion system to a Performance-oriented system similar to those implemented in England and other countries. To achieve this, we mate several proposals for the introduction of the performance-oriented system. We divide the main features of our proposals into three categories, including a reformed concessionaire selection system, a performance orientation in preparation of the concession agreement, and a performance orientation in contract management, and discuss each. 1'his study describes performance-oriented promotion systems in an output-focused way As this is an initial study on the introduction of performance orientation in private participation, various key points and proposals were identified. However, in the future, detailed research in technical fields and systems, legal research, and practical projects will be needed for implementation

• Journal of Korean Society of Rural Planning
• /
• v.26 no.1
• /
• pp.23-38
• /
• 2020

This study is aimed at the deduction of the important priority factors by setting the comprehensive rate in each of the economy, sociability and environmental areas for the sustainable development of fishing villages. As the research methods, review of domestic and overseas literature and Delphi questionnaire survey on experts, and hierarchical structure analysis were executed. Accordingly, this study is aimed at providing the basic data at the time of establishing plans by assessing the level of importance and priorities for each item through the deduction of the elements necessary for the fishing village plan. Key results of the study are as follows. First, as the results of review of domestic and overseas literature related to sustainability indices of fishing villages, a total of 50 items in the areas of economy, sociability and environment were deduced. Second, validity for each area was confirmed through Delphi questionnaire survey on experts. Third, as the results of factor analysis conducted on the basis of the hierarchical structure analysis for detailed items for each sector, 3 factors in the economic area, 2 factors in the social area and 3 factors in environment area were deduced. Fourth, as the results of the relative importance of the higher tiers, economic sector (0.528) displayed results that are more than 2 times higher than the social (0.261) and environmental (0.212) sectors. Establishment of foundation for independent competition (0.105), balanced development of small fishing village (0.086) and population engaged in economic activities in comparison to the fishing village population (0.077) were analyzed as the most important detailed items. Based on these results, experts pointed out that the economic sector is most important for the sustainable development of fishing village and, in detail, priority must be placed on the balanced development on the basis if the extent of independence of the fishing villages, and emphasized activation of residents engaged in economic activities in fishing villages in order to support them. That is, in order to increase the level of independence of the fishing villages, it was determined that there is a dire needs for expansion of diversified specialized businesses and infrastructural facilities through agreement by the residents capable of economic activities, and means of activating fishing villages through securing of budget at the local autonomous government level to provide support for the residents.

• Environmental and Resource Economics Review
• /
• v.17 no.1
• /
• pp.165-196
• /
• 2008

This paper reports a quantitative meta analysis of the economic impacts of localized noxious and contaminated sites. Using either hedonic property value or stated preference methods, economists have studied the effects of contamination or noxious activities, or the benefits realized from their elimination, on real estate prices at more than 40 sites. In support of wise public and private investments in environmental quality, most of these studies aim to inform decision makers about the benefits of remediation and cleanup. Their results vary considerably, but there has been no previous systematic effort to analyze the differences and identify shared insights. This study uses established methods of meta analysis to identify points of agreement and differences in this body of literature. The studies are characterized by the type of site, modeling approach, geographic extent of impacts, data features, and other key factors that underlie their value estimates. The impact estimates are normalized as proportional effects on property values. This study attempts to discover whether the estimated economic impacts of contamination or noxious activity differ according to these characteristics of the studies, and whether anything general can be said about the economic consequences of site contamination and remediation. Bivariate, multivariate, and logit techniques are applied to the data. The results suggest that the property value is the most sensitive to water base contamination, published case studies result in systematically greater environmental value than those in unpublished reports, and real estate markets show responses to environmental condition changes.

• Journal of Korean Society on Water Environment
• /
• v.31 no.2
• /
• pp.181-195
• /
• 2015

Algal blooms in lakes are one of major environmental issues in Korea. A three-dimensional, hydrodynamic and water quality model was developed and tested in Lake Euiam to assess the performance and limitations of numerical modeling with multiple algal groups using field data commonly collected for algal management. In this study, EFDC was adopted as the basic model framework. Simulated vertical profiles of water temperature, dissolved oxygen and nutrients monitored at five water quality monitoring stations from March to October 2013, which are closely related to algal dynamics simulation, showed good agreement with those of observed data. The overall spatio-temporal variations of three algal groups were reasonably simulated against the chlorophyll-a levels of those estimated from the limited monitoring data (chlorophyll-a level and cell numbers of algal species) with the RMSEs ranging from 2.6 to $17.5mg/m^3$. Also, note that $PO_4-P$ level in the water column was a key limiting factor controlling the growth of three algal groups during most of simulation period. However, the algal modeling results were not fully attainable to the levels of observation during short periods of time showing abrupt increase in algae throughout the lake. In particular, the green algae/cyanobacteria and diatom simulations were underestimated in late June to early July and early October, respectively. The results shows that better understanding of internal algal processes, neglected in most algal modeling studies, is necessary to predict the sudden algal blooms more accurately because the concentrations of external $PO_4-P$ and specific algal groups originated from the tributaries (mainly, dam water releases) during the periods were too low to fully capture the sharp rise of internal algal levels. In this respect, this study suggests that future modeling efforts should be focused on the quantification of internal cycling processes including vertical movement of algal species with respect to changes in environmental conditions to enhance the modeling performance on complex algal dynamics.