• Water for future
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• v.29 no.3
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• pp.129-142
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• 1996

This study investigates the magnitude of errors that can be expected in integrating sediment concentration in a vertical, basede on a single-point measurement, because of errors in input data. Potential error sources, including sampler location, water surface elevation, bed elevation, fall velocity, $\beta$ value, and $\kappa$ value were comparatively examined using data from a special study on the Rio Grande Conveyance channel in New Mexico. It is concluded that simple forms of equations for the vertical distribution of velocity and sediment concentration based on a single-point field sample of suspended sediment. The most uncertain point in the computation is related to the Rouse number z in the equation for the vertical concentration distribution of suspended sediment.

• Communications for Statistical Applications and Methods
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• v.12 no.2
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• pp.285-294
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• 2005

This paper deals with the comparison of parameter estimation methods in a 3-parameter Kappa distribution which is sometimes used in flood frequency analysis. Method of moment estimation(MME), L-moment estimation(L-ME), and maximum likelihood estimation(MLE) are applied to estimate three parameters. The performance of these methods are compared by Monte-carlo simulations. Especially for computing MME and L-ME, three dimensional nonlinear equations are simplified to one dimensional equation which is calculated by the Newton-Raphson iteration under constraint. Based on the criterion of the mean squared error, L-ME (or MME) is recommended to use for small sample size( n$\le$100) while MLE is good for large sample size.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.6 no.4
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• pp.302-308
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• 2005

The temperature distribution and fluid flow in the chamber was investigated using FLUENT code. It provides comprehensive modeling capabilities for a wide range of incompressible or compressible and laminar or turbulent fluid flow problems. And a broad range of mathematical models for transport phenomena is combined with the ability to model for complex geometries. The geometry of the chamber was very complex, and a simplified model of the chamber was used in the simulation experiment. It was important that the temperature deviation of test site. This datum were provided in the improving the control algorithm. Using this algorithm, the results were with in $0.1^{\circ}C.$

• Proceedings of the KSME Conference
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• 2000.04b
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• pp.25-30
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• 2000

Plate and shell heat exchanger(P&SHE) has been applied to the refrigeration and air conditioning systems as evaporators or condensers fur their high efficiency and compactness. The purpose of this study is to analyze the characteristics of pressure drop in plate and shell heat exchanger. An experiment for single phase (low pressure drop in plate and shell heat exchanger was performed. Also numerical work was conducted using the FLUENT code for $ {\kappa}-{\varepsilon}$ model. The dependence of friction factor on geometrical Parameters was numerically investigated. The study examines the internal flow and the pressure distribution in the channel of plate and shell heat exchanger. The results of CFD analysis compared with experimental data, and the difference of frictor factor in plate side and shell side are 10% and 12%, respectively. Therefore, the CFD analysis model is effectively predict the performance of plate and shell heat exchanger.

• Proceedings of the Korea Information Processing Society Conference
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• 2005.11a
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• pp.361-364
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• 2005

본 논문에서는 순서 통계량을 이용한 유한 고장 NHPP 모형들이 제안되었다. 이 모형들은 결함당 고장발생률이 단조 증가하거나 단조 감소하는 패턴을 가진다. 그리고 수명 분포에서는 기존의 모형들과 비교하고 kappa(2) 분포를 이용한 소프트웨어 신뢰성 모형을 제안하여 이 모형의 특성과 효율성에 대하여 제시하였다. 고장 간격 시간 자료를 이용한 무한고장 NHPP 모형들에 대한 모수 추정은 최우 추정법을 사용하였고 적용 분포들의 적용을 용이하게 하기 위하여 특수한 형태를 제시하였다. 실제고장 자료를 이용한 자료분석에서는 편차자승합을 이용한 모형 선택과 적합도 및 치우침 검정을 실시하여 그 결과를 나열 하였다.

• Journal of the Earthquake Engineering Society of Korea
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• v.10 no.1 s.47
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• pp.33-39
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• 2006

Parameters including the seismic sources and the elastic wave propagation characteristics were analysed using the observed ground motions from 3 Kyoungju region earthquakes. The Levenberg-Marquardt algorithm was applied to invert all the variables non-linearly and simultaneously with S wave energy In frequency domain. Average stress drop of 3 events and local attenuation parameter ${\kappa}$ were estimated to about 48-bar and 0.0312 respectively. Regional attenuation parameter, Qo and ${\eta}$, were also estimated to be about 417 and 0.83. ${\kappa}$ values are much higher than that of EUS, even though smaller than that of WUS. All these values resultant from this study show that there are differences in some parameters of other studios due to differences in the governing equation. of acceleration motions

• Communications for Statistical Applications and Methods
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• v.3 no.1
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• pp.243-255
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• 1996

The number of neutron signals from a neutral particle beam(NPB) at the detector, without any errors, obeys Poisson distribution, Under two assumptions that NPB scattering distribution and aiming errors have a circular Gaussian distribution respectively, an exact probability distribution of signals becomes a Poisson-power function distribution. In this paper, we show that the error rate in simple hypothesis testing for the limiting Poisson-power function distribution is not zero. That is, the limit of ${\alpha}+{\beta}$ is zero when Poisson parameter$\kappa\rightarro\infty$, but this limit is not zero (i.e., $\rho\ell$>0)for the Poisson-power function distribution. We also give optimal decision algorithms for a specified error rate.

• Asian-Australasian Journal of Animal Sciences
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• v.32 no.11
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• pp.1776-1788
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• 2019

Objective: The demands for measures to improve disease resistance and productivity of livestock are increasing, as most countries prohibit the addition of antibiotics to feed. This study therefore aimed to uncover functional feed additives to help enhance livestock immunity and disease resistance, using Acanthopanax sessiliflorus fruit extract (ASF). Methods: ASF was extracted with 70% EtOH, and total polyphenolic and catechin contents were measured by the Folin-Ciocalteu and vanillin assay, respectively. The 3D4/31 porcine macrophage cells ($M{\Phi}$) were activated by phorbol 12-myristate 13-acetate (PMA), and cell survival and growth rate were measured with or without ASF treatment. Flow-cytometric analysis determined the lysosomal activity, reactive oxygen species levels (ROS), and cell cycle distribution. Nuclear factor kappa B ($NF-{\kappa}B$) and superoxide dismutase (SOD) protein expression levels were quantified by western blotting and densitometry analysis. Quantitative polymerase chain reaction was applied to measure the lipid metabolism-related genes expression level. Lastly, the antibacterial activity of 3D4/31 $M{\Phi}$ cells was evaluated by the colony forming unit assay. Results: ASF upregulated the cell viability and growth rate of 3D4/31 $M{\Phi}$, with or without PMA activation. Moreover, lysosomal activity and intracellular ROS levels were increased after ASF exposure. In addition, the antioxidant enzyme SOD2 expression levels were proportionately increased with ROS levels. Both ASF and PMA treatment resulted in upregulation of $NF-{\kappa}B$ protein, tumor necrosis factor $(TNF){\alpha}$ mRNA expression levels, lipid synthesis, and fatty acid oxidation metabolism. Interestingly, co-treatment of ASF with PMA resulted in recovery of $NF-{\kappa}B$, $TNF{\alpha}$, and lipid metabolism levels. Finally, ASF pretreatment enhanced the in vitro bactericidal activity of 3D4/31 $M{\Phi}$ against Escherichia coli. Conclusion: This study provides a novel insight into the regulation of $NF-{\kappa}B$ activity and lipid metabolism in $M{\Phi}$, and we anticipate that ASF has the potential to be effective as a feed additive to enhance livestock immunity.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.8
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• pp.3581-3586
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• 2014

Aim: To investigate the effects of tetramethypyrazine (TMP) on proliferation and apoptosis of the human gastric carcinoma cell line 7901 and its possible mechanism of action. Methods: The viability of TMP-treated 7901 cells was measured with a 3-(4, 5-dimethyl-thiazol-2-yl)-2,5-diphenyltetrazolium bromide assay (MTT) and cell apoptosis was analyzed by flow cytometry. The distribution of cells in different phases of cell cycle after exposure of TMPs was analyzed with flow cytometry. To investigate the molecular mechanisms of TMP-mediated apoptosis, the expression of NF-${\kappa}Bp65$, cyclinD1 and p16 in SGC-7901 cells was analyzed by reverse transcription-polymerase chain reaction (RT-PCR) and western blotting. Results: TMP inhibited the proliferation of human gastric carcinoma cell line 7901 in dose and time dependent manners. Cell growth was suppressed by TMP at different concentrations (0.25, 0.5, 1.0, 2.0 mg/ml), the inhibition rate is 0.46%, 4.36%, 14.8%, 76.1% (48h) and 15.5%, 18.5%, 41.2%, 89.8% (72h) respectively. When the concentration of TMPs was 2.0mg/ml, G1-phase arrest in the SGC-7901 cells was significant based on the data for cell cycle distribution. RT-PCR demonstrated that NF-${\kappa}Bp65$ and cyclin D1 mRNA expression was significantly down-regulated in 7901 cells treated with 2.0 mg/ml TMP for 72h (p<0.05), while the p16 mRNA level was up-regulated (p<0.05). The protein expression of NF-${\kappa}Bp65$ and cyclin D1 decreased gradually with the increase in TMP concentration, compared with control cells (p<0.05), while expression of protein p16 was up-regulated (p<0.01). Conclusion: TMP exhibits significant anti-proliferative and pro-apoptotic effects on the human gastric carcinoma cell line SGC-7901. NF-${\kappa}Bp65$, cyclinD1 and p16 may also play important roles in the regulation mechanisms.

• Korean Journal of Community Nutrition
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• v.7 no.4
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• pp.548-558
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• 2002

The purpose of this study was to develop a computer software program for nutritional assessment using a Semi-Quantitative Food Frequency Questionnaire (SQFFQs) and the 24-hour Recall Method. The software for the SQFFQ was divided into input, output, and database. For dietary analyses, recipe and food databases were used. The recipe database included 25 items and the food database was divided into 18 food groups. The food database was composed of 19 general nutrient items, 33 fatty acids, and 18 amino acids. The software developed in this study can be summarized as follows: 1) input items related to the individual s ages information, lifestyle, biological values, and dietary habits; 2) individualized data in percent of the Korean RDA, the energy ratios of carbohydrates, proteins and fats, the ratio of animal to plant source intakes, and the distribution of food group intakes; 3) Statistical data on the individual's information, lifestyle, biological values, and dietary intakes including the frequency of intake of cooked foods, the amounts of food, and the number of food groups, and nutrients. In the 24-hour Recall Method, the input and output consisted of the individual s information and cooked dish intakes. The individual s report included the amounts of nutrient intake according to number of meal and days, in comparison to the Korean RDA, the energy ratio for carbohydrates, proteins and fats, the ratio of animal to plant source intakes, and the distribution of food group intakes. The statistical report presented the number of food groups and foods, and the nutrient intakes. To evaluate the validity of the SQFFQ, the Spearman Rank Order Correlation and kappa values were used. As a result, correlation coefficients comparing the 24-hour Recall Method appeared to be more than 0.5, except for vitamin $B_1, B_2$, niacin, and vitamin E. The kappa values for energy and carbohydrate intakes were both 0.7, and protein, fat, vitamin C, folate, Ca, and iron intakes ranged from 0.3 to 0.7.