• Journal of the Society of Cosmetic Scientists of Korea
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• v.50 no.3
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• pp.261-270
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• 2024

In this study, the effects of relieving itching and improving the barrier due to moisturizing human skin were evaluated for the cream containing Siraitia grosvenorii extract, which is effective in suppressing histamine and improving skin inflammation in the study subjects with itching. 43 female volunteers aged 21 ~ 59 years old (experimental group: 21 and control group 22) suitable for the purpose of the study were used for 4 weeks on the anterior gourd. The evaluation measured the amount of skin moisture and transepidermal moisture loss (TEWL) in the left or right anterior gourd before and after use of the product, and the visual analogue scale (VAS) evaluation due to skin drying, the efficacy and usability questionnaire evaluation of the product, and skin safety evaluation were conducted. As a result of the analysis, compared to before product use, both the experimental group and the control group showed significant improvement effects according to product use 4 weeks after use on the evaluation items of skin moisture and transepidermal moisture loss and the VAS due to skin dryness. In particular, the experimental group showed a significant improvement effect compared to the control group. As a result of the survey on the efficacy and usability of the product, the subjects of the study in the test group showed higher satisfaction than the control group in the case of the items "relieving itching (suitable)", "moisturizing" and "smoothing" after four weeks of use. In terms of usability, the subjects of the study in the experimental group showed higher satisfaction than the control group in the case of the "scent" and "feeling" items. Based on the above results, it is believed that "cream containing S. grosvenorii extract" has an itch relief (barrier improvement) effect due to skin moisturizing and can be used as a functional product for itching and barrier function improvement.

• Journal of Pharmacopuncture
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• v.11 no.4
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• pp.15-24
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• 2008

Objective The aim of this study is to investigate if Sweet Bee Venom(SBV) Therapy has the equal effect in comparison with Bee Venom (BV) Therapy on Chronic Lower Back Pain. Methods Clinical studies were conducted to 39 patients who were treated Chronic Lower Back Pain in Dept. of Acupuncture and Moxibustion, Dongeui University from March 1 to June 30, 2008. Subjects were randomly devided into 2 groups : BV treated group(Group A, n=19), SBV treated group(Group B, n=20) In BV treated group(Group A), we treated patients with dry needle acupuncture and BV Therapy. In SBV treated group(Group B), we treated patients with dry needle acupuncture and SBV Therapy. All process of treatment were performed by double blinding method. 1. To estimate the efficacy of venom in controlling pain, we have checked Visual Analog Scale(VAS). 2. For evaluating functional changes of patients, we have checked Oswestry Lower Back Disability Questionnaire(ODI). 3. To estimate Itching which is the most prominent symptom of allergic reaction, we have checked Visual Analog Scale(VAS). Results 1. In controlling pain, the results of BV treated group(Group A) is more effective than that of SBV treated group(Group B). 2. In promoting function, the results of BV treated group (Group A) is more effective than that of SBV treated group(Group B). 3. In controlling itching, the results of SBV treated group(Group B) is more effective than that of BV treated group(Group A). Conclusions According to the study, SBV Therapy shows more effective result than BV Therapy in controlling itching. But BV Therapy is more effective than SBV Therapy in controlling pain and promoting function.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.48 no.4
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• pp.303-312
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• 2022

In this study, Cyperus rotundus (C. rotundus) was fractionated into ethyl acetate to identify α-cyperone, a representative indicator, and its ethyl acetate fraction were evaluated to confirm the possibilityas a functional cosmetic ingredient. As a result of HPLC analysis, it was confirmed that the content of α-cyperone was 5.243%. In order to verify the inflammatory relief effect of the ethyl acetate fraction from C. rotundus (EAFC) and α-cyperone, it was confirmed that nitric oxide (NO) production inhibitory ability in RAW 264.7 macrophages induced an inflammatory reaction with lipopolysaccharide (LPS). Real-time qPCR analysis confirmed inhibition of mRNA expression level of inflammatory factors, IL-1β, IL-6, TNF-α, COX-2 and iNOS. As a results of conducting a clinical study using a simple cosmetic formulation containing EAFC, it was confirmed that the skin irritation stimulated by sodium lauryl sulfate (SLS) was calming and relieving itching. Through these results, it is believed that the C. rotundus can be used as a natural cosmetic ingredient that has the effect of inhibiting inflammation and relieving itching.

• Journal of the Korean Burn Society
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• v.22 no.2
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• pp.30-33
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• 2019

Purpose: Wound healing and scar management of donor site after skin graft should not be overlooked. Patients continue to complain of dryness, itching sensation. Such discomfort can cause irritation to the patients and lead to delayed healing or secondary infection. Thus, the author predicted Eucalyptus Oil, which acts on Transient Receptor Potential Melastatin 8 would be effective in regulating scar by reducing itching sensation in donor site when combining conventional silicone materials. Methods: The study was performed on 30 patients who underwent split thickness skin graft with lateral thigh as donor site between January 2017 and August 2018. First, primary evaluation of fully epithelized donor site scar three weeks after surgery was conducted. Control group (n=15) applied silicone gel (Kelo-cote, USA) solely two times a day. study group (n=15) applied Eucalyptus oil, combined with silicone gel. After 3 months of follow up, donor scar was evaluated using Vancouver scar scale and VAS scores of subjective patient reports regarding pain and itching sensation. Results: It was confirmed that both groups showed stable scar improvement comparing scar quality for 3 months. After 3 months, scar quality in study group showed superiority in pigmentation, pliability and pruritus compared to control group. Conclusion: Application of Eucalyptus Oil combined with conventional silicone gel is favorable to scar management and may give additional benefit of alleviating pruritis symptoms.

• Journal of Physiology & Pathology in Korean Medicine
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• v.16 no.1
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• pp.197-200
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• 2002

Seborrheic dermatitis is acute or chronic inflammatory disease frequently caused by heredtary factor, endocrine abnormality, alcohol, etc. and characterized by red spots with clear boundary itching. It is similar to Myunyoupung in Oriental Medicine. I prescribed the Seungmahwangryun-tang(升麻黃連湯) and Zowiseunggi-tang(調胃承氣湯) to a patient with Seborrheic dermatitis. After taking above medicines. the patient was cured.

• The Journal of Korean Medicine
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• v.22 no.4
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• pp.151-157
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• 2001

We observed and treated a 25 year-old male who had been diagnosed with atopic dermatitis. Even though he had been treated with western medicine, he still complained of severe itching, erythema, lichenification, scaling, dryness, oozing and insomnia. We treated him with general management, acupuncture, herbal irrigation, aromatherapy and three kinds of herb-medication (Sopung-san, Chunghulsamul-tang, Saenghyulyunbu-yum) without steroids. Having been treated for 60 days, his symptoms were reduced and mild grade in SCORAD (SCORing Atopic Dermatitis).

• The Journal of Pediatrics of Korean Medicine
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• v.20 no.2
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• pp.93-100
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• 2006

Objectives : The purpose of this study is to report Molluscum Contagiosum in an infant. Methods : We reported 5-year-old male patient who suffered from Molluscum Contagiosum. We treated him with Gami-Okbyungpung-tang. Results : After this treatment, the symptoms(papule on both thigh and gluteal sulcus region, itching) were improved. Conclusion : We had goal effects in oriental medical treatment on Molluscum Contagiosum. The further study is needed.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.15 no.1
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• pp.253-258
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• 2002

The 4-year-old female patient who has been suffer from papules, vesicles, pustules, scabs, itching underwent oriental treatment after she failed to see a remedial value from treatment at a local hospital. The authors report that above symptoms disappeared after she received orienta medical treatment such as herb and external medicine.

• Safety and Health at Work
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• v.3 no.2
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• pp.101-103
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• 2012

To identify the allergy problem of a 36-year old swimming instructor, who experiences heavy itching and rashes whenever she comes in contact with pool water. Patch tests were performed with European standard series and materials from the work floor. A positive patch test to aluminum chloride and flocculant was observed. Occupational dermatitis is, based on a contact allergy to aluminum chloride in the flocculant.

• CELLMED
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• v.13 no.1
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• pp.6.1-6.3
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• 2023

Objective: A case resport on the improvement of hand eczema through Ortho-Cellular Nutrition Therapy Methods: Two years of repeated improvement and worsening of hand eczema in a 68-year-old Korean woman resulted in pain and decreased quality of life. Results: After nutritional therapy, hand eczema improved. Conclusion: Nutritional therapy can help patients with chronic hand eczema improve inflammation, itching, depression, and insomnia.