• 대한암한의학회지
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• 제25권1호
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• pp.11-24
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• 2020

Objective : Radiodermatitis is a common sequelae in 95% of patients receiving radiation therapy, which is important to be well managed as it can affect the patient's quality of life as well as the cancer treatment schedule. The aim of this study is to review and summarize the interventions available for the treatment of acute radiodermatitis, including traditional Korean medicine, and to propose treatment algorithms for clinicians. Methods : To collect studies about managements for radiodermatitis, domestic and foreign database were used such as Korean journal of traditional knowledge portal (KTKP), Korean studies information service system (KISS), national discovery or science leaders (NDSL), and oriental medicine advance searching integrated system (OASIS), Pubmed, Google scholar and Scopus. Results : Thirty-two studies were selected. There were nine studies on usual care and dressing, eleven studies on chemical agents, two studies on biological preparations, and ten studies on herbal medicines. Conclusion : Hygienic options and dressings have proved to be useful in the management of radiodermatitis. Chemical agents such as corticosteroid, statin, and topical antibiotic agent have proved to alleviate symptoms and severity, regenerate damaged skin, and prevent secondary infection. In biological preparations, EGF (epidermal growth factor) and GM-CSF (granulocyte-macrophage colony-stimulating factor) could be used to protect skin and prevent radiodermatitis. For herbal medicines, Calendula, catechin, β-sitosterol, and Jaungo (紫雲膏) may be effective for symptoms including pain, itching, and burning sensation induced by radiation therapy. Because of some research with conflicting results, further studies are needed to propose an algorithm for more optimal treatments.

• Clinical and Experimental Pediatrics
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• 제45권6호
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• pp.800-803
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• 2002

1개월 동안의 양안 이물감 및 소양감을 주소로 내원한 2세 된 남아의 양안 상, 하안검 첩모에서 세극등 검사상 사면발이의 성충과 충란을 관찰 후 확진 하였다. 치료로 충란과 성충의 직접제거 및 첩모제거술, 20% fluorescein dye 도포와 세척을 시행하였고 광학현미경과 주사전자현미경으로 충란과 성충을 관찰하였다. 1주 간격으로 1달간 추적관찰 하였고 세극등검사상 양안의 안검과 첩모에서 성충 또는 충란이 발견되지 않아 완치 판정을 내렸다. 본 증례를 문헌 고찰과 함께 보고하는 바이다.

• The Korean Journal of Pain
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• 제26권4호
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• pp.374-378
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• 2013

Background: Incisional pain is particularly troublesome after hysterectomy. A method called transversus abdominis plane block (TAPB) has shown promise in managing postoperative pain. In this study, we evaluated the analgesic efficacy of ultrasound-guided TAPB after hysterectomy at different time points and at each time point separately for 48 hours. Methods: Forty-two patients (ASA I, II) who were electively chosen to undergo total abdominal hysterectomy were divided into 2 groups, control (group C) and intervention (group I). Twenty-one patients underwent TAPB (group I) and 21 patients received only the standard treatment with a fentanyl pump (group C). Both groups received standard general anesthesia. For patients in group I, following the surgery and before emergence from anesthesia, 0.5 mg/kg of ropivacaine 0.2% (about 20 cc) was injected bilaterally between the internal oblique and transverse abdominis muscles using sonography. Pain scores using the Visual Analogue Scale (VAS) and drug consumption were measured at 2, 6, 12, 24, and 48 hours after TAPB. Results: There were no significant differences in demographics between the two groups. VAS scores appeared to be lower in group I, although there was no interaction with time when we compared mean VAS measurements at different time points between group I and group C (P > 0.05). The amount of fentanyl flow was consistently higher in group C, but when we compared the two groups at each time point separately, the observed difference was not statistically significant (P < 0.053). The incidence of vomiting was 10% in group I and 28% in group C. There were no complaints of itching, and sedation score was 0 to 3. There were no complications. Conclusions: This study showed that TAPB did not result in a statistically significant decrease in VAS scores at different time points. TAPB did lead to decreased fentanyl flow, but when we compared the two groups at each time point separately, the observed difference was not statistically significant.

• Journal of Pharmaceutical Investigation
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• 제37권4호
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• pp.217-222
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• 2007

To develop cleansing tissue composed of silicone multiple emulsions which could easily remove make-up residues and confer skin protecting effect without damaging skin, we formulated various silicone multiple emulsions and evaluated the physicochemical properties including viscosity, cleansing effect, and safety effect. Also, cleansing tissue incorporated with silicone multiple (W/Si/W) emulsion was stored for 6 months, and judged its stability through microscopes under accelerated and long-term condition. Cleansing effect was evaluated by chromameter. Skin hydration effect was determined by corneometer and incorporation effect into non-woven fabric cotton was evaluated by volunteer survey. Low viscosity ranged from 400 centipoise (cP) to 1,000 cP was obtained from a stabilized W/Si/W emulsion containing more than 10% volatile silicone. Mean diameter of fresh W/Si/W emulsion was $20{\mu}m$, but after storage for 3 months at $45^{\circ}C$, the particle size of the W/Si/W emulsion increased up to $50{\mu}m$. Both W/Si/W emulsion-incorporated cleansing tissue and commercial product showed equally good cleansing effect. In addition, skin allergies such as erythema, edema, scaling itching, stinging, burning, tightness and prickling were not observed through macroscopic examination. From the transepidermal water loss results, the cleansing tissue consisting of W/Si/W emulsion showed superior hydration effect to commercial product. In conclusion, this study suggests cleansing tissue using W/Si/W emulsion could be used for an excellent efficacy compared with commercialized cleansing tissue.

• 한국생활과학회지
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• 제18권5호
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• pp.1093-1101
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• 2009

To provide basic data to manufacture superior brassieres, we performed a survey on the wearing and buying habits, and preference of functions and materials of brassieres for 189 women subjects in their twenties. The results of this research are as follows; Style and size are the most important in purchasing brassieres. Flat breasted and sagging breasted subjects were dissatisfied in the fit of the upper cup. 70% of the subjects were ignorant of their brassiere size. Sagging breasted subjects were less satisfied with smoothness, softness, and weight when wearing their bras in comparison with the other types. Conical type breasts were common amongst women in their 20s. They are more likely to wear size 75A and 80A where the full bust girth is 10cm larger than the under-bust. They preferred demi cup brassieres with thin or moderate padding to full cup brassieres with thick padding. On the other hand, 56.8% of subjects wore brassieres all day. The subjects were dissatisfied with the slipping down of the shoulder straps. Large-breasted subjects were concerned more with dampness and the fit on the center front of the brassiere, and brassieres with too thick padding had a poor fit on the center front. Sports-brassieres which fit close to the skin and used stretchable fabric caused more itching and dampness and dissatisfaction in removal of the brassiere.

• 한방안이비인후피부과학회지
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• 제22권2호
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• pp.163-175
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• 2009

Objective : The aim of this study was to take a census of elementary school children who have atopic dermatitis(AD) especially the residents of Je-Cheon. Method : We conducted a questionnaire survey of the elementary school children in Je-Cheon who have atopic dermatitis. 96 patients with AD were involved in the survey. The questionnaire was made up of their family history, past history, weaning food, breast-fed or not, dietary treatment and Children's Dermatology Life Quality Index(CDLQI), etc. The student's T-test was used for statistical analysis. Results : Parents and siblings brothers and sisters past history has an effect on patients with AD. With regard to past history of patients, allergic rhinitis was the most common ailment. Formula feeding was common in the group under 6 months of age and the mean age of the start of weaning was 7.25 months. Fruit juice and weaning food of powder type were the first weaning foods in this study. Many parents introduced a grain diet, live diet, bone - soup, egg, milk, cheese and bean curd to their children under 12 months of age. A restricted diet was the most common dietary treatment method in this study. The highest scoring question for CDLQI was itching; the lowest one was related to bullying. Conclusion : We analyzed the patients' family history, past history, weaning food, dietary treatment and Children's Dermatology Life Quality Index(CDLQI), etc. Through this survey, we better understand the actual conditions of elementary school children who had AD in Je-Cheon.

• 대한임상독성학회지
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• 제10권1호
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• pp.33-36
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• 2012

Opioids are the one of the most commonly used drugs to control cancer pain all over the world. But, we should not overlook the potential risk of opioid intoxication because they have well-known detrimental side effects. The opioid intoxication can be diagnosed thorough various clinical manifestations. The altered mental status, respiratory depression, and miosis is very representative clinical features although these symptoms don't always appear together. Unfortunately the opioid-toxidrome can be varied. A 42 years old man came to our emergency room after taking about 900 mg morphine sulfate per oral. He was nearly alert and his respiration was normal. Even though his symptoms didn't deteriorated clinically, serial arterial blood gas analysis showed increase in PaCO2. So we decided to use intravenous naloxone. Soon, he was fully awaked and his pupils size was increased. After a continuous infusion of intravenous naloxone for 2 hours, PaCO2 decreased to normal range and his pupil size also returned to normal after 12 hours. Though the levels of serum amylase and lipase increased slightly, his pancreas was normal according to the abdominal computed tomography. He had nausea, vomit, and whole body itching after naloxone continuous infusion, but conservatively treated. We stopped the continuos infusion after 1 day because his laboratory results and physical examinations showed normal. As this case shows, it is very important to prescribe naloxone initially. If you suspect opioid intoxication, we recommend the initial use of naloxone even though a patient has atypical clinical features. In addition, we suggest intranasal administration of naloxone as safe and effective alternative and it's necessary to consider nalmefene that has a longer duration for opioid intoxication.

• 한국콘텐츠학회논문지
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• 제15권1호
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• pp.308-315
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• 2015

본 연구는 3D 프린터를 이용하여 통풍이 원활하고 위생적이며 선명한 방사선영상을 구할 수 있는 그물형 손목 부목을 제작하고자 하였다. 스캐너는 의료용 다중단층영상장치(MDCT)를 이용했으며, 3D 프린터 기기는 용융 적층 조형술(fused deposition modeling, FDM)의 프린팅 방식을 이용했다. 소재는 분해성 플라스틱 (poly lactic acid, PLA)을 사용하였다. 손목의 3 차원 볼륨렌더링은 MDCT에서 획득된 단층영상으로 구현하였다. 구현된 손목 3 차원 영상을 바탕으로 가상의 그물형 부목 모형을 디자인하고 출력하였다. 그 결과 3D 프린터로 출력된 부목이 기존 부목보다도 우수한 방사선 손목영상을 획득할 수 있었으며 가려움증 및 비위생적인 단점을 개선하고 부목 해체 작업이 용이하였다. 결론적으로 본 연구에서 모델링된 3D 부목 모형은 향후 3D 프린팅 부목 제작에 기초자료로 활용할 수 있으며 환자들의 실생활에 도움을 줄 것으로 기대한다.

• 혜화의학회지
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• 제14권2호
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• pp.113-126
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• 2005

Atopic dermatitis(AD) is a chronic disease that affects the skin. "Atopic" refers to a group of diseases where there is often an inherited tendency to develop other allergic conditions, such as asthma and hay fever. In AD, symptoms vary from person to person. The most common symptoms are dry, itchy skin and rashes on the face, inside the elbows and behind the knees, and on the hands and feet. Although AD may occur at any age, it most often begins in infancy and childhood. The cause of AD is not known, but the disease seems to result from a combination of hereditary and environmental factors along with malfunction of the body's immune system. In contrast to that, the results from literatual study in oriental medicine are as follows; 1. The causes of AD are considered to be Mosusigisadok(母受時氣毒), Waegampoongsubyeol(外感風濕熱), Guasiksinlayeolmul(過食辛辣熱物), Ohbokonje(誤服溫劑). 2. The symptoms are fever, flushed face, red eyes, oliguria, constipation and itching. 3. Chungyeolhaedok(淸熱解毒) would be the basic method of treatment, and it divides into two categories; Subhyung(濕型) and Gunhyung(乾型). In Subhyung(濕型), AD is treated by Josub(燥濕), Chungyeol(淸熱) and Jiyang(止痒) whereas Chungyeol(淸熱), Jiyang(止痒), Jesub(除濕) in Gunhyung(乾型). 4. To prevent further damage and enhance quality of life, it is necessary to keep the temperature and humidity favorable, and healing the skin and keeping it healthy are important. Developing and sticking with a daily skin care routine is critical to preventing flares. Changing the diet and psychological stability may also be helpful to relieve symptoms of AD.

• 한국패션뷰티학회지
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• 제2권2호
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• pp.34-47
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• 2004

The objective of this study is to investigate the perception of males about make-up and the make-up process, analyze principal factors affecting their decision when purchasing cosmetics and, ultimately, to provide basic data for further survey and research into features of cosmetics and their satisfaction. The subjects of the study a.e male adults living in Jeonju, Iksan and Gunsan cities of Jeonbuk province. Surveyors made direct interviews with the subjects from October 21 to 30, 2003 and collected 174 questionnaires from them, which were subsequently put to the final analysis. The demographic characters of the surveyed showed that 60.9% of them were in the age ranging 30 to 39, 75.3% married, 69.5% undergraduates or graduates, 39.1% self-employed, 25.9% earning more than 3.01 million Won monthly and 43.7% spending less than 10,000 Won a month for cosmetics. Their make-up and purchasing pattern of cosmetics featured that 54.0% of the surveyed use cosmetics for skin care, 54.0% for cleanness and health, 84.5% for foundation(lotion or skin lotion) only, and 60.9% once a day. Out of the surveyed males, 79.3% haven't experienced any adverse side effects after make-up. Of those who experienced, 80.5% named disagreement of cosmetics with skin for the reason. As for kind or symptom of the side effects, 38.8% set forth itching. Among those who had aftermath or intoxication from make-up, 52.8% said they could recover naturally. According to the survey, 57.5% felt somewhat awkward after make-up, but not quite bad though. Thirty-seven point nine percent of the males surveyed replied they cared little about the purpose of male-oriented cosmetics. Quality was raised by 31.0% as the foremost issue to improve. Television turned out to be the main source for 56.9% of the surveyed to get information about cosmetics. For 56.35%, general discount shops are preferred to buy cosmetics and 24.7% of them take ones recommended by salespeople. When buying cosmetics, 47.1% considered color and fragrance most seriously.