• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.20 no.2 s.33
• /
• pp.187-198
• /
• 2007

Background : Atopic dermatitis is a chronic and recurrent allergy eczema, called as 'Tae-yul'. It is a characteristic dermatitis, diagnosed from baby to adult, that carries severe itching. Objectivd : The aim of this trial is to examine the effect and safety of Medibebe in patients with atopic dermatitis. Methods : We made a comparison between before and after the use this product. Volunteers who satisfied the requirements were enrolled in the study. Degrees of severity of atopic dermatitis were measured by SCORAD index. Results : After 4 weeks' use of Medibebe, SCORAD index showed a decrease of $20.0{\pm}10.2$(95% C.I: 17.1-22.9) compared with when it was not applied, which is a statistically meaningful change(p-value<0.0001). Subjective pruritus and Sleeping loss reported after both 2 and 4 weeks' use of Medibebe decreased in a statistically meaningful way(p-value<0.0001) compared with before the application. but, 2 cases out of all 50 subjects for the clinical trial were excluded on the way. Conclusion : As a result of applying the 4 items of Medibebe(cream, lotion, soap, and body cleanser) to patients with atopic dermatitis and watching the progress, it is concluded and considered that these cleansing and moisturizing products can be used by atopic patients safely and effectively with almost no side-effect.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.20 no.2 s.33
• /
• pp.230-239
• /
• 2007

Introduction : Atopic dermatitis is very epidermic disease in these days. Atopic dermatitis is difficult for patient to be treated because there is no specific treatment. The oriental method of atopic dermatitis is varied as patient situation and doctor's view point. The Treatise on Febrile Diseases(傷寒論) may be a hint for atopy disease. Object: Although we use various method such as acupucture, aroma therapy, a medicine for external use, we use the two decoctions in the Treatise on Febrile Diseases according to differentiation of syndromes and abdominal diagnosis. Result : After inpatient treatment in 21 days, the itching, redness, exudation, crust, lichen get better and insomnia and constipation was removed quickly. The SCORAD index is decreased from 84.2 to 25.9. Conclusion : These decoction can treat the atopic dermatitis although there is no symptom in atopy because we cure the all situation of the patient. We can cure the atopic dermatitis not only by routine remedy for various symptoms but also by diagnosis and treatment based on overall analysis of symptoms and signs.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.29 no.3
• /
• pp.231-239
• /
• 2016

Objectives : Pruritus is a skin disorder that usually occurs in the elderly. The purpose of this study is to report the effect of external preparation containing Ponciri fructus and Radix lithospermi on senile pruritus and xeroderma with liver cirrhosis.Methods : We treated 85-years-old liver cirrhosis patient suffered from itching sensation on the whole body with external preparation containing Ponciri fructus and Radix lithospermi and oral administration of Sodalgeonbitang for 37 days.Results : Despite discontinuing western medical treatment of topical steroids and oral antihistamine, pruritus and erythema of the patient were significantly improved.Conclusions : As for external application, decoction of Ponciri fructus and Radix lithospermi might be effective used for treatment senile pruritus and xeroderma.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.20 no.3
• /
• pp.212-221
• /
• 2007

Objectives : This study was conducted to test patients with Atopic Dermatitis by external application with Gynostemma Pentaphyllum MAKINO in cosmetics. Methods : We gave scores to 59 patients who visited the Dept. of Oriental Medical Opthalmology & Otolaryngology & Dermatology of Daegu Hanny Oriental Medical Center from July 1st, 2005 to December 31th. We checked the clinic index score(extent. intensity : the degree of erythema, induration or papulation, puritus, excorination, lichenification, scaling or dryness, erosion or oozing or weeping. the degree of itching), Eosinophil count and IgE. Results : There are 46 patients we could check by clinic index score, and 44 patients by laboratory. 1. In the 46 cases clinic index score was significantly decreased between the before- and afterexternal application treatment periods(P<0.01). 2. The 46 cases was devided into two types (moist heat type and blood dryness type) by intensity. External application of Gynostemma Pentaphyllum MAKINO in cosmetics did not significant change by two types. 3. In the 44 laboratory cases, the number of eosinophil counts was decreased but the number of IgE was significantly increased. Conclusions : Considering the above results, we have concluded that cosmetics with Gynostemma Pentaphyllum MAKINO have the remedical effect for Atopic Dermatitis.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.23 no.3
• /
• pp.216-224
• /
• 2010

Objective : The purpose of this study was investigated the effect of auricular Acupuncture treatment in Allergic rhinitis patients. Methods : This study was carried out on the 16 allergic rhinitis patients who had been treated at Cheongdogun public health center for The Good-Breath program. The Good-Breath program included auricular acupuncture was performed 2 times a week during 4 weeks. Auricular acupuncture points used were M101(肺), M13(副腎), M16(內鼻), M22(內分泌), M33(額), M55(神門). Patients nasal symptoms and QOL were assessed before and after 4 weeks treatment by the Severity Scoring Systems of Rhinitis(SSSR) and Quality of Life Questionnaire for Korean Rhinitisian(QLQKR). Results : 1. Total Severity Scoring Systems of Rhinitis(SSSR) Scores were significantly improved. but Each items was no significant difference. 2. Among items of QLQKR, Itching worry about western medicine worry about change of environment Role limitation-physical were significantly improved. and Total Quality of Life Questionnaire for Korean Rhinitisian(QLQKR) Scores were significantly improved.

• Journal of The Korean Society of Clinical Toxicology
• /
• v.4 no.1
• /
• pp.65-68
• /
• 2006

Contact urticaria describes a wheal and falre response elicitied within 30-60 minutes after cutaneous exposure to certain agents. Contact urticaria encompasses a number of different clinical manifestations and the symptoms which can vary from the mildest forms of burning, stinging and itching sensation to life-threatening anaphylaxis referred to as contact urticaria syndrome. Cefotiam is one of the most popular second generation cephem antibiotic used in korea. Since 1975, contact urticaria due to cephalosporins has been reported, and also, in japan, this reported from about last 15 years. Recently we experienced three nurses working at the general wards with showing contact urticaria and anaphylaxis after occupational exposure to cefotiam antibiotics.

• Parasites, Hosts and Diseases
• /
• v.48 no.4
• /
• pp.313-317
• /
• 2010

A case of tick bite was found in the inguinal region of a 74-year-old Korean woman. She was attacked by the tick while working in her vegetable garden in the vicinity of mountain located in Suncheon City, the southern coastal area of the Korean Peninsula. On admission she complained of mild discomfort and itching around the bite area. The causative tick was 23 mm long and had slender pedipalps. The scutum was quite ornate and had eyes at the edge. The genital aperture was located anterior to the level of the coxa II. The spiracular plate was comma-shaped and the anus was surrounded posteriorly by the anal groove. The coxa I had subequal 2 spurs; the external one slightly larger. The spur of coxa IV was slightly longer than those of coxae II and III. The tarsus IV had 2 distinct subapical ventral spurs. It was identified as the fully engorged adult female of Amblyomma testudinarium. This is the first human case of Amblyomma bite in Korea.

• Korean Journal of Adult Nursing
• /
• v.26 no.2
• /
• pp.214-222
• /
• 2014

Purpose: This study was to identify factors predicting the occurrence of depression among patients with hepatitis C treated with Peg-interferon. Methods: The subjects were 134 patients treated with Peg-interferon after the diagnosis with hepatitis C at the D University Hospital and 3 hospitals located in Busan, South Korea. The predictors of depression were identified by measuring the general characteristics of the subjects and their disease-related characteristics, social support, sleep disorders, and degree of side effects by interferon. The data were analyzed with a t-test, ANOVA, and logistic regression using the SPSS/WIN 18.0 program. Results: Sixty-six point four percent of the subjects suffered from mild to more severe depression. Fatigue, hair loss, itching, and sleep disorders turned out to be significant predictors. In addition, the explanatory power of these variables for the occurrence of depression was 70%. Conclusion: Sleep disorders and drug side effects were determined to have significant influence on the development of depression in hepatitis C patients treated with Peg-interferon. Therefore, the development of nursing intervention programs aimed to prevent depression by effectively managing sleep disorders and side effects is mandated in future to help the given population.

• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.13
• /
• pp.5521-5524
• /
• 2015

Purpose: This analysis was conducted to evaluate the efficacy and safety of icotinib based regimens in treating patients with non-small cell lung cancer (NSCLC). Methods: Clinical studies evaluating the efficacy and safety of icotinib-based regimens with regard to response and safety for patients with NSCLC were identified using a predefined search strategy. Pooled response rates of treatment were calculated. Results: With icotinib-based regimens, 7 clinical studies which including 5,985 Chinese patients with NSCLC were considered eligible for inclusion. The pooled analysis suggested that, in all patients, the positive reponse rate was 30.1% (1,803/5,985) with icotinib-based regimens. Mild skin itching, rashes and diarrhea were the main side effects. No grade III or IV renal or liver toxicity was observed. No treatment-related death occurred in patients treated with icotinib-based regimens. Conclusions: This evidence based analysis suggests that icotinib based regimens are associated with mild response rate and acceptable toxicity for treating Chinese patients with NSCLC.

• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.12
• /
• pp.4997-4999
• /
• 2015

Advanced oral squamous cell carcinoma (SCC) is a possible risk factor for myiasis, a parasitic infestation of vital tissue of humans or other mammals by dipterous larvae (maggots). Oral myiasis is a rare entity, and is mostly associated with various medical and anatomical conditions, such as neglected mandibular fracture, lip incompetence, cerebral palsy, poor oral hygiene, suppurative lesions, and cancerous wounds. Larvae cause itching and irritation due to their crawling movements and can destroy vital tissues, inducing serious or even life-threating hemorrhage. The aim of the present article was to highlight the occurrence of oral myiasis in association with squamous cell carcinoma and also to highlight the treatment and preventive approaches for such cases. A literature search was performed using MEDLINE for articles published in English relating to the occurrence of oral myiasis in oral SCC. Our search revealed 6 reports on myiasis associated with oral SCC. The surgical debridement of infected tissue with the removal of maggots is the treatment of choice in most cases of oral myiasis.