• Journal of Chest Surgery
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• v.20 no.3
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• pp.578-581
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• 1987

A very rare form of intrapulmonary cyst is an enterogenous cyst two examples of which were described by Ward and Krahl [1942]. Microscopically, the cyst wall is lined by gastric or intestinal type of mucous membrane which may include islets of pancreatic tissue; their walls contain muscle but no cartilage. We recently experienced a case of intrapulmonary enterogenous cyst. The patient was 30-year-old-male who showed chest pain and tightness after chest trauma. Chest X-ray revealed pneumothorax in both lung field with giant bullae in left upper lung field, right 6th and 7th rib fracture. Left lower lobectomy including cyst was done and the postoperative course was uneventful.

• Proceedings of the Korean Society of Fisheries Technology Conference
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• 2003.05a
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• pp.396-396
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• 2003

Jeju Island, because of its location off the south coast of the Korean peninsula, has a varied marine mollusk fauna, As part of a continuing effort to enumerate and study the mollusks of the island, extensive SCUBA diving surveys have been done in the Sogwipo area, particularly around the islets of Munsom, Pomsum, and Supsum. (omitted)

• Polymer Science and Technology
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• v.22 no.5
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• pp.439-446
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• 2011

• Journal of Species Research
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• v.3 no.1
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• pp.79-94
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• 2014

It was found that a total of 94 species of marine algae, 13 green algae, 24 brown algae, and 57 red algae, are living at the seashore of Oho-ri in this study. 739 voucher specimens for 94 species were made based on plants from March to September 2010 at the 3 islets, including Heukdo, Goraebawi, and Juckdo. Voucher specimens were catalogued and deposited in the herbarium of the National Institute of Biological Resources (KB) of Korea.

• Development and Reproduction
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• v.11 no.2
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• pp.67-77
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• 2007

Replacement of insulin-producing cells represents an almost ideal treatment for patients with diabetes mellitus type 1. Transplantation of pancreatic islets of Langerhans is limited by the lack of donor organs. Therefore, generation of insulin-producing cells from human embryonic stem cells represents an attractive alternative. The present review summarizes the current knowledge on the differentiation of insulin-producing cells from human embryonic stem cells and their application to the cell therapy for treating diabetes mellitus.

• Korean Journal of Veterinary Research
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• v.32 no.3
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• pp.321-331
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• 1992

The regional distribution and relative frequency of gastrointestinal endocrine cells were studied immunohistochemically in the gastrointestinal mucosa and pancreas of the fresh water turtle. Ten kinds of endocrine cells were identified in the gastrointestinal tract. Cholecystokinin-8-, bovine pancreatic polypetide-and glucagon-immunoreactive cells were seen throughout the gastrointestinal tract, also among them cholecystokinin-8-immunoreactive cells were most predominant in segment III. Although gastrin- and gastrin/cholecystokinin-immunoreactive cells were found from segment III to VI and X, respectively, they were numerous in segment III. Somatostatin-immunoreactive cells were observed from segment I to VII. 5-hydroxytryptamine- immunoreactive cells were detected in segment I, III, VIII, IX and X. Human pancreatic polypeptide-immunoreactive cells were demonstrated in segment V, VI, VIII, IX and X. Insulin-immunoreactive cells were found from segment III to X except for segment VIII, but rare in segment VII. Neurotensin-immunoreactive cells were found to be restricted to segment VIII, IX and X. No porcine chromogranin-, substance P- and bombesin-immunoreactive cells were detected throughout the gastrointestinal tract of the fresh water turtle. Although typical mammalian pancreatic islets encapsulated by connective tissue were not present in this species, five kinds of endocrine cells-glucagon, insulin, somatostatin, bovine pancreatic polypeptide and 5-hydroxytryptamine-were found in forming small or large groups and scattered in the exocrine gland region. However porcine chromogranin- and motilin-immunoreactive cells could not be demonstrated in the pancreas.

• Journal of the Korean Society of Food Science and Nutrition
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• v.33 no.7
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• pp.1133-1138
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• 2004

This study has been carried out to investigate the effect of the administration of Rhemanniae Radix extract (5.0 mL/kg/day, RR group) on the hyperglycemic mice (HM group) induced with streptozotocin (STZ). In blood glucose level, RR group showed a significant decrease compared with HM group. The result of glucose tolerance test was more favorable in RR than HM group. A lot of insulin-positive cells and insulin-like growth factor-II positive materials were observed in RR group. A number of apoptotic particles were observed in the HM group, but several apoptotic nuclei were found in RR group. Pancreatic islets of HM group were destructed by the administration of STZ, but islets were recovered from damage in the RR group. These results suggest that administration of Rhemanniae Radix extract to the hyperglycemic mice prevent from the damage induced by STZ.

• The Korean Journal of Ecology
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• v.7 no.3
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• pp.132-157
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• 1983

This study was performed to investigated the flora and vegetation of Kokum-do island from July 1982 thru December 1983; and the findings hereof are summarized as follows: The flora investigated thereform comprises 737 species whih are classified into 128 families, 466 genera, 651 species, 79 varieties and 7 formae; and those which are worthy of close attention among the same include such endemic species of Korea as Celtis choseniana, Corylopsis coreana, Carpinus tschonoskii var. eximia and Tricyrtis dilatata, and a few plants, to be distributed in the north, such as Lilium distichum, Girardinia cuspidata and Orostachys sikokianus. Now that the said island belongs to the warm temperate zone, the distribution thereof consists of 120 species of evergreen plants including 74 species of evergreen broadleaf trees. The rich distribution of evergreen broadleaf trees in the island is thanks to the plantation thereof by the public organizations for scenic beauty. The destruction of flora in this island was caused by felling, fire nization and other human activities around 1940, and in particular, has been correlated with the population densiity of Yonhong-do, Sanghwa-do, and Hahwado islets; and that of top soil and ground vegetation in he quarry area of Ojon-ri town resulted from the collection of natural rocks an stones. It is evaluated as necessary that such evergreen broadleaf trees as Castanopsis cuspidata var. thunbergii, Machillus thunbergii and Ligustrum japonicum of Hyongje-do. Chun-do, Tok-do, Taech'wi-do, and Soch'wi-do islets, andPhyllostachys bambusoides, Caesalpinia japonica and Albizzia julibirssin of Kokum-do island, and Machillus thunbergii of Hongryon-ri town be under protection. The average DGN of the whole archipelago proves to be 5.84, which shows the tendency of the inverse proportion to the number of resident population per unit area. The pteridophyta distributed in this island comprises 39 species, and the coefficient of cryptogam as to the destruction of vegetation shows a high value of 1.4 which is regarded as indicating the diversified distribution of pteridophyta, forestbed shade plants under the forestbeds of some wellpreserved lots of this island. The naturalized plants, distributed in this island, were found out comprising a total of 23 species, and the Urbanization Index(UI) as to the destruction degree of natural vegetatioin shows a low value of 20.9.

• BMB Reports
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• v.44 no.11
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• pp.713-718
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• 2011

In this study, the effects of sitagliptin analogue (SITA) or pioglitazone (PIO) treatment on glucose homeostasis and ${\beta}$-cell dynamics in animal models of type 2 diabetes-Akita and db/db mice were evaluated. After 4-6 weeks of treatment, both SITA and PIO were shown to lower non-fasting glucose levels and reduced glycemic excursion in the intraperitoneal glucose tolerance test. In addition, both drugs preserved normal islet structure and the proportion of ${\beta}$-cells in the islets. Compared to the controls, SITA treatment induced a higher ${\beta}$-cell proliferation rate in Akita mice and a lower rate of apoptosis in db/db mice, whereas PIO treatment induced a lower rate of apoptosis in db/db mice and reduced proliferation rates in Akita mice. In conclusion, both SITA and PIO appear to exert some beneficial effects on the islet structure in addition to glycemic control via different mechanisms that involve ${\beta}$-cell dynamics in Akita and db/db mice.

• Journal of Physiology & Pathology in Korean Medicine
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• v.22 no.2
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• pp.422-426
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• 2008

In this study, the preventive effects of Radix Trichosanthis extracts (RTE) against cytokine-induced ${\beta}-cell$ death were assessed. Cytokines generated by immune cells infiltrating pancreatic islets are crucial mediators of ${\beta}-cell$ destruction in insulin-dependent diabetes mellitus. The treatment of RIN cells with $interleukin-1{\beta}$ ($IL-1{\beta}$) and $interferon-{\gamma}$ ($IFN-{\gamma}$) resulted in a reduction of cell viability. RTE protected $IL-1{\beta}$ and $IFN-{\gamma}$-mediated viability reduction in a concentration-dependent manner. Incubation with RTE also induced a significant suppression of $IL-1{\beta}$ and $IFN-{\gamma}$-induced inducible nitric oxide synthase (iNOS) protein expression. The molecular mechanism by which RTE inhibited iNOS protein expression appeared to involve the inhibition of $NF{-\kappa}B$ activation. The $IL-1{\beta}$ and $IFN-{\gamma}$-stimulated RIN cells showed increases in $NF{-\kappa}B$ binding activityand $I{\kappa}B{\alpha}$ degradation in cytosol compared to unstimulated cells. However, pretreatment with RTE inhibited cytokines-induced $I{\kappa}B{\alpha}$ degradation and $NF{-\kappa}B$ activation in RINm5F cells. Furthermore, the protective effects of RTE were verified via protection of impairment in glucose-stimulated insulin secretions in $IL-1{\beta}$ and $IFN-{\gamma}$-treated islets.