• Journal of Chest Surgery
• /
• 제39권7호
• /
• pp.549-552
• /
• 2006

심각한 허혈성 심근병증(ischernic cardiomyopathy, ICMP)에 동반된 승모판 폐쇄부전증에 있어서 심장이식이 여의치 않은 상황에서의 수술적 치료로는 경색이 아닌 부위의 심근(viable myocardium)에 대한 관상동맥 우회술(coronary revascularization)과 좌심실 용적 축소술(LV reduction), 승모판 재건술(mitral reconstruction)이 그 중심으로 자리잡고 있다. 허혈성 심근병증에 있어서 승모판 폐쇄 부전은 다양한 병인으로 나타나며, 그 중 판막륜의확장 외에도 유두근의 전위가 중요한 원인으로 지적되고 있다. 본원에서는 승모판 폐쇄 부전증을 동반한 좌 주 관상동맥을 포함한 심한 관상동맥질환과 허혈성 심근병증 환자에 대한 관상동맥 우회술과 함께, 좌심실 절개를 통한 승모판 뒤판엽 성형술(posterior mitral annuloplasty), 유두근 단축술(Papillary muscle plication)의 수술적 치험을 보고하고자 한다.

• Journal of Chest Surgery
• /
• 제44권3호
• /
• pp.236-239
• /
• 2011

Indication for extracorporeal membrane oxygenation (ECMO) has been extended as the experience of ECMO in various clinical settings accumulates and the outcome after ECMO installation improves. We report two cases of successful mitral valve surgery for severe ischemic mitral regurgitation in patients on ECMO support for cardiogenic shock which developed upon coronary angiography.

• Journal of Korean Biological Nursing Science
• /
• 제23권4호
• /
• pp.308-317
• /
• 2021

Purpose: The purpose of this study was to elucidate the relationship between readiness to quit smoking and smoking cessation, and identify factors associated with smoking cessation in smokers with ischemic heart disease post-coronary angiography (CAG). Methods: This descriptive study was conducted between December 1, 2020 and May 14, 2021 at a P hospital, Busan. A total of 164 subjects completed the questionnaire including general characteristics, coronary artery disease characteristics, readiness to quit smoking, and smoking cession behavior during hospitalization and 4 weeks after discharge. Results: The success rate of smoking cessation after coronary angiography in patients with ischemic heart disease was 49.4% (n = 81). In addition, 48.2% of smokers (n = 83) attempted smoking cessation after CAG, while 39.8% showed changes in smoking behavior. The readiness to quit smoking was significantly associated with smoking cessation (OR= 2.23, p< .005). Conclusion: Readiness to quit smoking was identified as an important factor associated with smoking cessation in patients with cardiovascular disease in this study. In order to increase the smoking cessation rate, it is necessary to strengthen the readiness to quit smoking, followed by a tailored program for smoking cessation in patients with ischemic heart disease.

• Journal of Cardiovascular Imaging
• /
• 제26권4호
• /
• pp.226-228
• /
• 2018

• 대한핵의학회지
• /
• 제39권2호
• /
• pp.146-149
• /
• 2005

Various stem cells or progenitor cells are being used to treat cardiovascular disease in ischemic heart disease, stem ceil therapy is expected to regenerate damaged myocardium. To evaluate effects of stem cell treatment, the method to image stem cell location, distribution and differentiation is necessary. Optical imaging, MRI, nuclear imaging methods have been used for tracking stem cells. The methods and proglems of each imaging technique are reviewed.

• Nuclear Medicine and Molecular Imaging
• /
• 제41권2호
• /
• pp.91-96
• /
• 2007

The measurement of pathologically low levels of tissue $pO_2$ is an important diagnostic goal for determining the prognosis of many clinically important diseases including cardiovascular insufficiency, stroke and cancer. The target tissues nowaday have mostly been tumors or the myocardium, with less attention centered on the brain. Radiolabelled nitroimidazole or derivatives may be useful in identifying the hypoxic cells in cerebrovascular disease or traumatic brain injury, and hypoxic-ischemic encephalopathy. In acute stroke, the target of therapy is the severely hypoxic but salvageable tissue. $^{18}F-MISO$ PET and $^{99}mTc-EC-metronidazole$ SPECT in patients with acute ischemic stroke identified hypoxic tissues and ischemic penumbra, and predicted its outcome. A study using $^{123}I-IAZA$ in patient with closed head injury detected the hypoxic tissues after head injury. Up till now these radiopharmaceuticals have drawbacks due to its relatively low concentration with hypoxic tissues associated with/without low blood-brain barrier permeability and the necessity to wait a long time to achieve acceptable target to background ratios for imaging in acute ischemic stroke. It is needed to develop new hypoxic marker exhibiting more rapid localization in the hypoxic region in the brain. And then, the hypoxic brain imaging with imidazoles or non-imidazoles may be very useful in detecting the hypoxic tissues, determining therapeutic strategies and developing therapeutic drugs in several neurological disease, especially, in acute ischemic stroke.

• 대한방사선기술학회지:방사선기술과학
• /
• 제32권1호
• /
• pp.69-78
• /
• 2009

연구배경 및 목적 : 심혈관 질환은 서구에서는 이미 오래전부터 가장 흔한 사망 원인으로 알려져 있고, 우리나라를 포함한 동양에서는 최근 식생활 습관의 변화와 함께 급격히 증가하는 추세에 있다. 특히 허혈성 심장질환은 통계청 curve : 곡선 $1996{\sim}2006$을 보면 향후 $5{\sim}10$년 사이 허혈성 심장질환이 1위로 올라 갈 것으로 전망할 수 있다. 이에 보다 정확하고 정밀한 선별검사가 필요함을 인식할 수 있겠다. 목적은 Calcium-scoring의 총 정량화수치에 영향을 주는 위험인자와의 연관성을 알아보고, Calciumscoring이 선별검사로의 타당성을 검증하며, 국민보건에 이바지 하고자 한다. 연구방법 및 결과 : 인천광역시에 위치한 G병원으로 2008년 2월 1일부터 6월 30일까지 가슴 흉통으로 내원한 환자 중 Calcium-scoring과 Coronary CT angiography를 동시에 시행한 환자 중 무작위 표본추출로 70명을 선정 하였으며, Calcium-scoring t value에 영향을 주는 것으로 알려진 위험인자를 각각의 연관성을 분석한 결과 고지혈증, 고혈압이 유의수준 $\alpha$ < 0.05하에서 Calcium-scoring t value를 높임을 알 수 있었고, Calcium-scoring t value를 Coronary CT angiography 결과와 비교분석 한 결과 관상동맥 석회화 수치는 관상동맥 내의 동맥경화와의 총량과 상관관계가 높다는 결과를 얻을 수 있었고, Coronary CT angiography result를 확진검사로 ROC curve를 분석한 결과 Area의 크기가 0.833으로 우수한 검사법이라 할 수 있고, Asymptotic 95% Confidence interval Low Bound와 Upper Bound가 모두 0.5 이상이며, Asymptotic Sig.(p)가 0.05보다 작으므로 유용한 검사법임을 알 수 있었다. 결 론 : Calcium-scoring검사가 허혈성 심혈관 질환의 다른 선별검사인 심전도와 운동부하검사 등과 더불어 선별검사로서 손색이 없으며, 운동부하검사의 제한점인 관절 질환을 앓고 있거나, 고령 등의 원인으로 운동이 어려운 경우에는 시행하기 어려운 점을 해결할 수 있는 우수한 선별검사라고 할 수 있겠다.

• Journal of Chest Surgery
• /
• 제26권4호
• /
• pp.271-275
• /
• 1993

In this country, the number of patients with coronary artery disease is progressively increasing with the change of life style and improvement of the diagnostic procedures. In addition, the medically invasive procedure for treating ischemic heart disease was rapidly developed and the surgical patients have more complex and multiple lesions and more surgical risks. Fifty three patients with ischemic heart disease underwent coronary bypass grafting [CABG] for recent 24 months. Twenty patients had three-vessel disease, 17 patients two-vessel disease, and 2 patients single-vessel disease. The average number of distal anastomoses was 3.3 per patient with the range of I to 6 grafts. Forty-one patients [77.4 %] had preoperative left ventricular ejection fraction of 50 % or more and 14 patients[26.4%] had a significant left main coronary lesion. Saphenous vein grafts were employed in 52/53 patients [98.1%] and internal mammary grafts, which were anastomosed to left anterior descending artery, in 38/53 patients[71.7%]. Two patients, whom percutaneous transluminal coronary angioplasty failed for, underwent emergency CABG with only saphenous vein grafts and both patients survived.The hospital mortality was 1.9 % and there was no late death. Perioperative myocardial infarction occurred in 1.9%. All survivors were asymptomatic[in 83% of the patients] and/or improved over their preoperative status. Twenty-nine patients were included in blood conservation group and 21 patients [72.4 %] underwent CABG without any homologous blood transfusion. Our early result of coronary bypass grafting was comparable to that which was reported in other coronary surgery units.

• 한국초전도학회:학술대회논문집
• /
• 한국초전도학회 2009년도 Korea Superconductivity Society Meeting 2009
• /
• pp.73-73
• /
• 2009

• 대한한의학회지
• /
• 제28권3호통권71호
• /
• pp.207-215
• /
• 2007

Objectives : The objective of this study was to assess whether there were sex differences in stroke types, risk factors, warning signs, and stroke complications among patients with first-ever stroke. Methods : Six-hundred seventy six patients with first-ever stroke were recruited at the Department Cardiovascular and Neurologic Diseases (Stroke center) of KyungHee University Oriental Hospital, DongGuk University International Hospital, and Kyungwon University In-cheon Oriental Medical Hospital from September 2005 to June 2007. Patients were hospitalized within 28 days after the onset of stroke. We investigated their stroke types, ischemic stroke subtypes by TOAST classification, risk factors, warning signs, stroke complications, general characteristics such as age, sex, etc. Results : Overall, 347 patients were male and 279 female. Compared with males, female patients were significantly older (mean age 67.3${\pm}$1.1 versus 62.4${\pm}$1.6 years) (P=0.000). We did not find significant sex differences in stroke types or ischemic stroke subtypes by TOAST classification. History of hypertension was significantly more frequent in female than male patients (P=0.000). Among stroke complications, urinary tract infection was significantly more frequent in female than male patients (P=0.003). Among warning signs, blepharospasm was significantly more frequent in female than male patients (P=0.006). Conclusions : Knowledge of sex differences of stroke patients can help us gain better insights on the characteristics of stroke patients. We need further and larger scale research to acquire more concrete conclusions on this theme.