• The Korean Journal of Gastroenterology
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• v.72 no.5
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• pp.252-257
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• 2018

This guidance is an updated version of the irritable bowel syndrome (IBS) guidelines based on evidence-based medicine. IBS is a common chronic gastrointestinal syndrome that occurs in approximately 10% of the population and causes chronic abdominal pain as well as bowel habit changes, such as stool frequency or consistency. The final diagnosis of IBS is based on the exclusion of organic diseases that would explain the symptoms and the absence of endoscopic abnormalities. IBS can reduce the quality of life and cause a major disease burden, such as repeated examinations and continuous drug use, by mistaking organic diseases including malignancy. The major changes are as follows: 1) when to perform a colonoscopy under the impression of IBS; 2) effect of a low-fermentable oligosaccharides, disaccharides, monosaccharides, and polyol diet; 3) impact of probiotics in IBS; and 4) role of antibiotics in IBS. The Korean Society of Neurogastroenterology and Motility recently updated these guidelines to support physicians for qualified medical services and reduce the socioeconomic burden of IBS.

• Herbal Formula Science
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• v.14 no.2
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• pp.9-20
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• 2006

Objective & Methods : Irritable Bowel Syndrome is occurred frequently in daily life. Nevertheless. medical treatment of the Irritable Bowel Syndrome is almost dependent on western cure, but that cure is not effective enough. So we chose the oriental medicine textbook that were dealing with the oriental concept and the treatment of Irritable Bowel Syndrome. we got these results. Results were as follows : 1. Irritable Bowel Syndrome is characterised by recurrent or chronic abdominal pain, with distension, disturbed defecation and psychic problems without organic lesions. 2. The etiology of Irritable Bowel Syndrome include stress. disharmony of liver and spleen, the coldness of spleen and kidney and the lack of qi or yin, etc. 3. The oriental treatments of Irritable Bowel Syndrome are warming spleen and kidney, easing liver and stopping diarrhea. 4. The internal medication of Irritable Bowel Syndrome was the most used 11 times Tongsayobang(痛瀉要方) and 10 times Yijungtang(理中湯). 5. The most many used herb were Atractylodjs macrocephalae rhjzoma(白朮), Gjnseng Radix (人蔘), Cjnnamomj Cortex(肉桂), Polyporus(猪笭), etc.

• Journal of Neurogastroenterology and Motility
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• v.24 no.4
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• pp.544-558
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• 2018

Because of the sex-gender differences that are shown in a diversity of physiological and psychological factors, it can be speculated that the clinical presentation of symptoms as well as treatment strategies in women and men with irritable bowel syndrome (IBS) may differ. Studies have revealed that IBS is more common in women than men. As for the IBS subtype, IBS with constipation is significantly more prevalent among women than men. Sex hormones and gender differences may play important roles in the pathophysiology of IBS. However, its pathophysiologic mechanisms still remain largely unknown, and therapeutic implications are limited. Moreover, women IBS patients have been reported to feel more fatigue, depression, anxiety, and lower quality of life than men IBS patients. Furthermore, there has been evidence of differences in the appropriate treatment efficacy to IBS in men and women, although relatively few men are enrolled in most relevant clinical trials. A more sex-gender-oriented approach in the medical care setting could improve understanding of heterogeneous patients suffering from IBS. An individualized and multicomponent approach including sex and gender issues might help improve the treatment of IBS.

• Journal of Sasang Constitutional Medicine
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• v.13 no.3
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• pp.134-139
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• 2001

The irritable bowel syndrome(IBS) is the most common gastrointestinal disorder in clinical practice and is characterized by abdominal pain associated with a chronic disturbance of defecation. It is important to discriminate IBS from organic bowel disease. Based on clinical and epidemiologic studies, specific symptom criteria for IBS have been developed. The subject is a 29 year old man who has abdominal pain, chronic diarrhea, general weakness, dizziness, insomnia and has been diagnosed as irritable bowel syndrome. We classified this as Shaoyangin Mangyin(少陽人 亡陰證) and prescribed Hyeongbangjiwhangtang(荊防地黃湯) in accordance with the principle of pyoeumganggi(表陰降氣). In the result, we had the improvement of his symptoms.

• The Journal of Internal Korean Medicine
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• v.40 no.5
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• pp.948-956
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• 2019

Objectives: The purpose of this study was to describe the effectiveness of Jeoreongchajeonja-tang as a treatment for patients with diarrhea-predominant irritable bowel syndrome (IBS-D). Methods: Two irritable bowel syndrome patients who had visited Semyung University Korean Medical Hospital were enrolled. The patients were diagnosed according to the Rome III criteria, and the treatment effect was assessed using the Gastrointestinal Symptom Rating Scale (GSRS) and the colon transit time. Results: After treatment with Jeoreongchajeonja-tang for 4 weeks, the GSRS score was improved and colon transit time was delayed. Conclusions: This study suggests that Jeoreongchajeonja-tang is effective for improving diarrhea-predominant irritable bowel syndrome. More extensive study is needed in the future.

• Nutrition Research and Practice
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• v.15 no.4
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• pp.411-430
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• 2021

Irritable bowel syndrome (IBS) is a frequently diagnosed gastrointestinal (GI) disorder characterized by recurrent abdominal pain, bloating, and changes in the stool form or frequency without any structural changes and overt inflammation. It is not a life-threatening condition but causes a considerable level of discomfort and distress. Among the many pathophysiologic factors, such as altered GI motility, visceral hypersensitivity, and low-grade mucosal inflammation, as well as other immunologic, psychologic, and genetic factors, gut microbiota imbalance (dysbiosis), which is frequently found in IBS, has been highlighted as an etiology of IBS. Dysbiosis may affect gut mucosal homeostasis, immune function, metabolic regulation, and even visceral motor function. As diet is shown to play a fundamental role in the gut microbiota profile, this review discusses the influence of diet on IBS occurring through the modulation of gut microbiota. Based on previous studies, it appears that dietary modulation of the gut microbiota may be effective for the alleviation of IBS symptoms and, also an effective IBS management strategy based on the underlying mechanism; especially because, IBS currently has no specific treatment owing to its uncertain etiology.

• The Journal of Pediatrics of Korean Medicine
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• v.31 no.3
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• pp.1-13
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• 2017

Objectives The purpose of this study is to investigate how irritable bowel syndrome (IBS) affects fatigue scales and eating habits in children and adolescents using Rome IV criteria. Methods Questionnaires and The $PedsQL^{TM}$ Multidimensional Fatigue Scale (MFS) have been given to 211 children and adolescents aged 8 to 18 years old who were admitted to ${\bigcirc}{\bigcirc}$ university Korean medicine hospital pediatric departments, from 29th, July, 2016 to 12th, August, 2016 to evaluate their eating habits and fatigue. Additionally, PASW statistics 18.0 were used to analyze influence of irritable bowel syndrome on eating habits and fatigue in children and adolescents by using chi-square test, independent t-test and linear regression. Results In total of 211 subjects, 29 (13.7%) were diagnosed with IBS according to the Rome IV criteria. 1. There was a statistically significant difference (p<0.05) between IBS group and non-IBS group on a specific question in the eating habit questionnaire: the amount of sugar intake and the prevalence of IBS. 2. There was a statistically significant difference in general fatigue and cognitive fatigue categories when comparing the MFS subscores according to the prevalence of IBS. Conclusions Considering patients eating habits and fatigue is a necessary process for the successful treatment of irritable bowel syndrome. Korean medicine that maximizes quality of life while minimizing the potential risks to the patients of gastrointestinal disease should also include administrative interventions that may be helpful in the daily life of IBS patients.

• Journal of Acupuncture Research
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• v.37 no.1
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• pp.59-63
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• 2020

The effects of complex Korean medicine treatment including acupotomy, on irritable bowel syndrome (IBS) are reported in this case study. A 54-year-old woman with diarrheal symptoms that alternatively improved and worsened for many years and worsening abdominal pain visited the emergency room and was diagnosed with IBS; she was admitted for approximately 2 weeks at the Acupuncture and Moxibustion Department of National Medical Center (NMC). Numerical rating scale (NRS), irritable bowel syndrome-quality of life (IBS-QOL), and gastrointestinal symptom rating scale (GSRS) scores were evaluated on the day of hospitalization, midway through the hospitalization period, and on the day of discharge. Abdominal pain was measured daily using NRS, and the score decreased from 8 at admission to 0 at discharge. The IBS-QOL percentile score improved from 42 points to 100 points. The total GSRS score also improved, from 30 points to 2 points. These results suggest that complex Korean medicine treatment with acupotomy, is useful for treating internal diseases, such as IBS, as well as musculoskeletal disorders.

• Biomedical Science Letters
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• v.26 no.4
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• pp.351-359
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• 2020

It is well known that irritable bowel syndrome (IBS) is related to psychological distress. However, only a few studies have investigated the relationship between IBS and various dimensions of psychological distress. This study aimed to evaluate the prevalence of IBS and its relationship with anxiety, depression, and stress in young female college students. A cross-sectional study was conducted using a self-report structured questionnaire with 673 female college students. IBS was diagnosed based on the Rome III criteria. For the evaluation of psychological distress on the IBS, we investigated Hospital Anxiety and Depression Scale (HADS) and Global Assessment of Recent Stress (GARS). The prevalence of IBS was 27.9%. In the univariate analysis, the anxiety, depression, and stress scores were significantly associated with IBS (P<0.001, P=0.001, and P<0.001, respectively). Multivariate analysis showed that anxiety (OR=1.07, 95% CI=1.01~1.15, P=0.032) and stress scores (OR=1.23, 95% CI=1.19~1.27, P<0.001) were independently correlated with the IBS. Among the subtypes of IBS, IBS with predominant constipation was the most common, and the anxiety, depression, and stress scores did not significantly differ between the subtypes. Our results suggest that anxiety and stress are closely related to IBS. Managing psychological distress should be considered in the treatment of IBS in young female college students.

• The Journal of Internal Korean Medicine
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• v.40 no.4
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• pp.629-636
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• 2019

Objective: This study was designed to assess the correlation between gastrointestinal symptoms, depression, and anxiety in patients with irritable bowel syndrome (IBS). Method: New patients who visited the ${\bigcirc}{\bigcirc}$ Oriental Hospital completed standardized questionnaires. These consisted of questionnaires for IBS based on Rome III criteria, the Gastrointestinal Symptom Rating Scale (GSRS), the Beck Depression Inventory (BDI), and the Beck Anxiety Inventory (BAI). Results: A total of 103 patients participated. Among them, IBS was observed in 42 patients. There was a weak correlation between GSRS and BDI, but it was not statistically significant. There was a statistically significant weak correlation between GSRS and BAI. The main symptom factors affecting BAI were borborygmus, increased flatus, sucking sensations in the epigastrium, and abdominal distension. Conclusion: There was a statistically significant correlation between gastrointestinal symptoms and anxiety in patients with irritable bowel syndrome.