• Title/Summary/Keyword: ion detector

Search Result 187, Processing Time 0.022 seconds

Reconstruction of In-beam PET for Carbon therapy with prior-knowledge of carbon beam-track

  • Kim, Kwangdon;Bae, Seungbin;Lee, Kisung;Chung, Yonghyun;An, Sujung;Joung, Jinhun
    • IEIE Transactions on Smart Processing and Computing
    • /
    • v.4 no.6
    • /
    • pp.384-390
    • /
    • 2015
  • There are two main artifacts in reconstructed images from in-beam positron emission tomography (PET). Unlike generic PET, in-beam PET uses the annihilation photons that occur during heavy ion therapy. Therefore, the geometry of in-beam PET is not a full ring, but a partial ring that has one or two openings around the rings in order for the hadrons to arrive at the tumor without prevention of detector blocks. This causes truncation in the projection data due to an absence of detector modules in the openings. The other is a ring artifact caused by the gaps between detector modules also found in generic PET. To sum up, in-beam PET has two kinds of gap: openings for hadrons, and gaps between the modules. We acquired three types of simulation results from a PET system: full-ring, C-ring and dual head. In this study, we aim to compensate for the artifacts that come from the two types of gap. In the case of truncation, we propose a method that uses prior knowledge of the location where annihilations occur, and we applied the discrete-cosine transform (DCT) gap-filling method proposed by Tuna et al. for inter-detector gap.

Gas-Liquid Chromatographic Determination of Amino Acids in Some Korean Foods (Gas-liquid chromatography에 의한 한국(韓國) 주요식품(主要食品)의 아미노산(酸) 함량측정(含量測定))

  • Park, Yaung-Ja
    • Applied Biological Chemistry
    • /
    • v.12
    • /
    • pp.43-51
    • /
    • 1969
  • The purpose of this study was to determine protein amino acid contents of some Korean foods by gas-liquid chromatography, and to evaluate this technique as a procedure for the quantitative determination of amino acids in foods. The crude protein content of foods was also estimated from the nitrogen content. 1. Nitrogen content of each food sample was determined previously to adjust the amount of sample for GLC analysis 2. In the analysis of 17 known amino acids, a linear relationship was found between the weight of 13 amino acids of 17 amino acids, the internal standard as well as the injection volume of a mixture and the detector responses for the derivatives of the amino acids. No response for arginine, cystein, histidine, and tyrosine was observed. 3. The relative molar response (RMR) values for the 13 amino acids of standard solution relative to glutamic acid as '1.00' were obtained under normal operating conditions with a hydrogen flame ionization detector. 4. The recovery of amino acids from their mixtures with natural food materials was carried out. The recoveries were essentially quantitative except threonine and serine. An overall mean recovery of 11 amino acids was $101.4{\pm}8.4$ per cent before hydrolysis and $98.1{\pm}8.7$ per cent after hydrolysis of samples. 5. The comparative analysis of the acid hydrolysates of two food samples by gas-liquid and ion-exchange chromatographic analysis were carried out. In white-bait pemmican, only threonine and asparagine amounts by GLC analysis had similar values to those obtained by ion-exchange chromatography. The other seven amino acids gave higher values as measured by GLC than by ion-exchange. With the food sample, soybean, alanine, valine, asparagine, and glutamic acid were in good agreement in two analysis, while leucine, proline, threonine, phenylalanine, and lysine were found in slightly higher concentrations in the GLC analysis. 6. Grant variations of amino acid content were found among samples analyzed. The amino acid contents of each sample were compared with the values found in the literature.

  • PDF

Monte Carlo Calculation for Production Cross-Sections of Projectile's Isotopes from Therapeutic Carbon and Helium Ion Beams in Different Materials

  • Quazi Muhammad Rashed Nizam;Asif Ahmed;Iftekhar Ahmed
    • Journal of Radiation Protection and Research
    • /
    • v.48 no.4
    • /
    • pp.204-212
    • /
    • 2023
  • Background: Isotopes of the projectile may be produced along the beam path during the irradiation of a target by a heavy ion due to inelastic interactions with the media. This study analyzed the production cross-section of carbon (C) and Helium (He) projectile's isotopes resulting from the interactions of these beams with different materials along the beam path. Materials and Methods: In this study, we transport C and He ion beams through different materials. This transportation was made by the Monte Carlo simulation. Particle and Heavy Ion Transport code System (PHITS) has been used for this calculation. Results and Discussion: It has been found that 10C, 11C, and 13C from the 12C ion beam and 3He from the 4He ion beam are significant projectile's isotopes that have higher flux than other isotopes of these projectiles. The 4He ion beam has a higher projectile's isotope production cross-section along the beam path, which adds more impurities to the beam than the 12C ion beam. These projectile's isotopes from both the 12C and 4He ion beams have higher production cross-sections in hydrogenous materials like water or polyethylene. Conclusion: It is important to distinguish these projectile's isotopes from the primary beam particles to obtain a precise and accurate cross-section result by minimizing the error during measurement with a nuclear track detector. This study will show the trend of the production probability of projectile's isotopes for these ion beams.

Extended Neutral Particle Analyzer System for the KSTAR

  • Kim, Sun-Ho;Gu, Dong-Jin;Park, Min;Ahn, Chan-Yong;Wang, Son-Jong;Kim, Sung-Kyu
    • Proceedings of the Korean Vacuum Society Conference
    • /
    • 2012.08a
    • /
    • pp.272-272
    • /
    • 2012
  • Additional neutral particle analyzer has been installed to investigate the variation of fast ion tails with regard to the line of sight during 2012 KSTAR campaign. The system has the same photo-diode particle detector as previous system [1]. Both newly installed system and previous system modifield for 2012 campaign have two channels. One has a particle stopper transparent to hard X-ray, the other has no one. It will be used to separate the hard X-ray component from total hard X-ray and fast neutral counts. It is expected to measure fast ion tails more clearly through this extended system. A detailed system and calibration result will be presented in the conference.

  • PDF

Superconducting Strip Ion Detectors for Time-of-flight Mass Spectrometer

  • Zen, N.;Suzuki, K.;Shiki, S.;Ukibe, M.;Koike, M.;Casaburi, A.;Ejrnaes, M.;Cristiano, R.;Ohkubo, M.
    • Progress in Superconductivity
    • /
    • v.14 no.2
    • /
    • pp.92-95
    • /
    • 2012
  • Superconducting detectors are promising as ion detectors for time-of-flight mass spectrometers (TOF MS). They can achieve mass-independent detection efficiency even for macromolecular bombardments, because output signals are produced through the deposited kinetic energy at ion impact instead of secondary electron emission that is the ion detection mechanism of conventional microchannel plate (MCP) detectors or secondary electron multipliers (SEM). Among the superconducting detectors, the superconducting strip ion detectors (SSIDs), which consist of several hundreds of superconducting lines with a width of a few hundreds nm and a thickness of a few tens of nm, have a fast response time of less than 1 ns. Inherently, the response time of SSIDs is determined by kinetic inductance, so that it was difficult to realize a fast SSID with a large detection area. However, we succeeded in realizing the detector size up to $5{\times}5mm^2$ without response time degradation by using a parallel configuration.

Ion-Pair Chromatography of Organic and Inorganic Anions (유기 및 무기음이온에 대한 이온쌍크로마토그래피)

  • Sam Woo Kang
    • Journal of the Korean Chemical Society
    • /
    • v.29 no.4
    • /
    • pp.365-371
    • /
    • 1985
  • A cationic dye, methylene blue $(MTB^+)$ was examined as a counter ion in the separation of organic and inorganic anions by ion-pair chromatography. Nonabsorbing anions could be indirectly detected by photometric detector with the assistance of MTB^+ in visible range (665nm). A mixture of anions was able to be separated with good base line resolution and high sensitivity. The capacity factors were also determined in various experimental conditions to study retention mechanism. The retention followed the ion-interaction model where the $MTB^+$ occupies a primary layer at the stationary phase while the analyte anion and other anions in the system compete for forming the secondary layer.

  • PDF

The development of photo-diode dosimeter(PD-2000) for the diagnostic X-ray Energy (X선 진단영역 에너지 측정을 위한 Photo-Diode 선량계(PD-2000)의 개발)

  • Kim, Sung-Chul;Lee, Woo-Chul;Kim, Jung-Min
    • Journal of radiological science and technology
    • /
    • v.23 no.2
    • /
    • pp.27-32
    • /
    • 2000
  • It was produced radiation dosimeter used photo-diodes for which ionization by x-ray was applied and evaluated the value of utility in clinics as compared with ion-chamber. The result obtained were as follows : 1. Comparison of ion-chamber with photo-diode dosimeter's x-ray output by the change of x-ray tube voltage, and the ratio of ion-chamber to diode was $0.96{\sim}1.02$ which was not affected by x-ray beam quality. 2. The ratio of ion-chamber to diode was 0.96 by change of tube current and 0.97 by change of exposure time that is not affected by x-ray quantity. 3. The ratio of ion-chamber to diode was $0.97{\sim}1.04$ by thickness and $0.93{\sim}1.10$ by radiation field that is little affected by second ray quantity. 4. Reproducibility of photo-diode dosimeter was 0.011(CV) and it is a good result. 5. Photo-diode dosimeter was affected by the surface angle of detector over 30 degrees. Produced dosimeter was small, light, and meets good result compared with ionization chamber. It was expected come into wide use in clinic.

  • PDF

Confirmation of carbamate pesticides by liquid chromatography coupled with electrospray ionization mass spectrometry (LC/MS를 이용한 카바메이트계 잔류농약 확인방법)

  • 박준조;금모래;고광춘;박병옥;이성식
    • Korean Journal of Veterinary Service
    • /
    • v.25 no.1
    • /
    • pp.23-29
    • /
    • 2002
  • A method was developed to separate, detect and qualify aldicarb, bendiocarb, carbaryl, carbofuran, ethiofencarb, methomyl, methiocarb, propoxur in meats and fruits. Experimental beef and fork samples were fortified with 0.05mg/kg of carbamate pesticides for analysis. Carbamate-detected pear by HPLC fluorescence detector(HPLC/FLS) are extracted with acetonitril and refined by solid phase extraction(SPE) filled with aminopropyl-bonded silca, In the following step, the injected materials into LC/MS are analyzed to result in the fact that bendiocarb, carbaryl, carbofuran, ethiofencarb, methomyl, methiocarb, propoxur presents several sorts of fraction ions following with; [M+H]$^{+}$, [M+Na]$^{+}$,[M-CONH$CH_3$]$^{+}$, [M-OCONH$CH_3$]$^{+}$. In addition, ethiofencarb presents [M-SCH$_2$$CH_3$]$^{+}$ ion distinctive and aldicarb presents [M+Na]$^{+}$ and [M-OCONH$CH_3$]$^{+}$ ion which is the most decisive fraction ion for pesticides such as bendiocarb, carbaryl, carbofuran, ethiofencarb, methiocarb, methomyl, propoxur excluding [M+H]$^{+}$ ion. However, [M-OCONH$CH_3$]$^{+}$ and [M-OCONH$CH_3$]$^{+}$ fraction ion charactering carbamate pesticides are detected most efficiently with fragment voltage 50ev. As a result, for rluantitative analysis, [M+Na]$^{+}$ ion is the most decisive ion for detection of aldicarb and [M+H]$^{+}$ ion is the most decisive fraction ion for Pesticides such as bendiocarb, carbaryl, carbofuran, ethiofencarb, methiocarb, methomyl, propoxur. Carbaryl-detected pear by HPLC/FLS are analyzed by L/MS and the result shows that [M+H]$^{+}$ and [M-CONH$CH_3$]$^{+}$ ions charactering carbaryl are detected.ering carbaryl are detected.

Feasibility Study of Parallel- Plate Detector Using Dielectric film for 6 MV X-ray (6MV X-선 검출특성 조사를 위하여 유전체 필름을 이용하여 제작한 평행판 검출기의 유용성)

  • 조문준;김용은;이병용;김정기;임상욱;김현수;김기환
    • Progress in Medical Physics
    • /
    • v.15 no.2
    • /
    • pp.105-111
    • /
    • 2004
  • The parallel plate detector with dielectric film for dosimetry was designed to measure detection characteristic of 6 MV X-ray with medical linear accelerator. PTFE film was inserted into FEP films that are made by two one-side metal coated materials for ion source. The thicknesses of PTFE dielectric film was 100 ${\mu}{\textrm}{m}$ and the thickness of FEP dielectric film was 100 ${\mu}{\textrm}{m}$, respectively. This detector was fixed by two acrylic plate for physical hardness ad geometrical consistency. The geometrical condition for measurement with parallel-plate for detector was below; SSD=100 cm and the 5 cm depth between detector and phantom surface The major parameter of detector characteristics such as zero drift current, leakage current, charge response by applied voltage, reproducibility, linearity, TMR measurement, dose rate effect were measured. The zero drift currents are 8.3 pA and leakage currents are 10 pA. The charge response of applied voltage is showing linearity in 414 voltage. The measurement deviation of reproducibility in this detector is within 1% for dose and the linearity of applied dose shows in this detector. The TMR curves in phantom between this parallel plate detector and reference detector are matched within 3% deviation from maximum dose depth to 7.5 cm depth. It is considered that this dosimetric system is satisfactory for the purpose of the constancy check of the 6 MV x-ray from medical linear accelerator.

  • PDF

Development of Hard-wired Instrumentation and Control for the Neutral Beam Test Facility at KAERI

  • Jung Ki-Sok;Yoon Byung-Joo;Yoon Jae-Sung;Seo Min-Seok
    • Journal of Electrical Engineering and Technology
    • /
    • v.1 no.3
    • /
    • pp.359-365
    • /
    • 2006
  • Since the start of the KSTAR (Korea Superconducting Tokamak Advanced Research) project, Instrumentation and Control (I&C) of the Neutral Beam Test Facility (NB-TF) has been striving to answer diverse requests arising from various facets during the project's development and construction phases. Hard-wired electrical circuits have been designed, tested, fabricated, and finally installed to the relevant parts of the system. In relation to the vacuum system I&C, controlling functions for the rotary pumps, a Roots pump, two turbomolecular pumps, and four cryosorption pumps have been constructed. I&C for the ion source operation are the temperature and flow rate signal monitoring, Langmuir probe signal measurements, gradient grid current measurements, and arc detector circuit. For the huge power system to be monitored or safely operated, many temperature measurement functions have also been implemented for the beam line components like the neutralizer, bending magnet, ion dump, and calorimeter. Nearly all of the control and probe signals between the NB test stand and the control room were made to be transmitted through the optical cables. Failures of coolant flow or beam line vacuum pressure were made to be safely blocked from influencing the system by an appropriate interlock circuit that will shut down the extraction voltage application to the system or prevent damages to the vacuum components. Preliminary estimation of the beam power through the calorimetric measurement shows that 87.9% of the total power of the 60kV/18A beam with 200 seconds duration is absorbed by the calorimeter surface. Most of these I&C results would be highly appropriate for the construction of the main NBI facility for the KSTAR national fusion research project.