• 지역연구
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• 제31권2호
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• pp.3-28
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• 2015

산업생태론과 생태론적 정책적 접근이 지역경제에 상당한 영향을 미치고 있지만, 지역 벤처생태계의 역동성과 제약점은 아직 제대로 검토되지 못하고 있다. 특히, 지역 벤처생태계의 내외적 상호작용과 협력적 메커니즘의 형성 내지 확보와 관련하여 전략적 중개활동에 대한 부가적인 연구가 필요한 상태에 있다. 본 연구는, 대구 경북지역의 벤처실태 분석을 토대로, 지역 벤처생태계의 내재적 제약으로서의 네트워크 현황, 산업기술상의 외재적 변화흐름과 지역적 현황으로서의 혁신 방향 방식 결과, 그리고 관련 지역적 수요 측면 등에서 지역 벤처생태계에서 전략적 중개활동의 필요성을 밝힌다. 특히, 지역 벤처생태계에서 네트워크 인프라 취약성 보완측면, 산업기술의 외재적 변화흐름과의 미스매치 현상 대처측면, 그리고 내생적 역량강화 추세 부응측면 등에서 전략적 중개활동의 역할 내용 및 범위 등을 탐색한다.

• 대한불안의학회지
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• 제10권1호
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• pp.44-51
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• 2014

Objective : The amygdala has been considered to be a critical region in the pathophysiology of social anxiety disorder, but subregional connectivity pattern has not been examined yet despite lots of previous functional neuroimaging studies. Methods : Resting-state functional magnetic resonance imaging data was obtained in 19 patients with social anxiety disorder and 20 normal controls, and default mode functional connectivity with each of basolateral, centromedial and superficial areas of the amygdala was measured and compared between the two groups. Results : Differential amygdala-based networks between the two groups were distributed to all over the brain. In particular, however, a bias on the amygdala-cingulate pathway was observed in the superficial amygdala only. Connectivity strengths between the superficial amygdala and perigenual anterior cingulate cortex were correlated with scores of social interaction and avoidance. Conclusion : Our findings provide new insights into understanding of the intrinsic cognitive bias model of social anxiety disorder. An abnormality in superficial amygdala-anterior cingulate connectivity may influence on cognitive processing of socially-relevant information in social anxiety disorder.

• 융합정보논문지
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• 제10권12호
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• pp.75-81
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• 2020

본 연구의 목적은 간호대학생의 COVID-19로 인한 감정, 직업가치관 및 취업준비행동과 관련이 있는지 알아보고 간호대학생의 교과 및 교과 외 활동에 대한 방안을 마련하고자 시도되었다. 연구대상은 일개 지역의 졸업학년인 간호학과 4학년 130명을 대상으로 설문지를 이용하였다. 자료분석은 SPSS Win 19.0 program으로 분석하였고, 상관관계는 Pearson's correlation 분석을 실시하였다.. 연구결과 COVID-19로 인한 감정의 평균점수는 3.61±0.62이었다. COVID-19로 인한 감정과 외재적 직업가치관는 유의한 상관관계가 있었다. 내재적 직업가치관과 취업준비행동는 유의한 상관관계가 있었다. 본 연구를 바탕으로 COVID-19 등과 관련된 교육 프로그램 제공 및 취업준비를 효과적으로 할 수 있는 취업프로그램 개발을 위한 기초자료로 제공하는데 의의가 있다.

• Journal of Oral Medicine and Pain
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• 제40권3호
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• pp.89-95
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• 2015

All living organisms have a biological clock that orchestrates every biological process and function, and this internal clock operates following a circadian rhythm. This biological clock is known to influence various clinical indicators such as blood pressure and body temperature. Also, the fluctuation of signs and symptoms of diseases including pain disorders are affected by circadian rhythm. It has been reported that the pain intensity of various somatic and neuropathic pain disorders show unique pain patterns that depend on the passage of time. The generation of pain patterns could be explained by extrinsic (e.g., physical activity, tactile stimulation, ambient temperature) and also intrinsic factors (neural and neuroendocrine modulation) that are related to the circadian rhythm. It is important to recognize and identify the individual pain pattern in pain therapy to approve treatment outcome. Moreover, chronotherapeutics which considers pain patterns and pharmacokinetics in context of the circadian rhythm could produce greater analgesia in response to medication. However, only a limited number of studies handle the issue of pain patterns according to circadian rhythm and chronotherapeutics in the orofacial region. The present review intends to reflect on the most recent and relevant data concerning the bidirectional relation between pain disorders of the orofacial region and circadian patterns.

• Molecules and Cells
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• 제21권3호
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• pp.428-435
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• 2006

Specific interaction of the epsin N-terminal homology(ENTH) domain with the plasma membrane appears to bridge other related proteins to the specific regions of the membrane that are invaginated to form endocytic vesicles. An additional $\alpha$-helix, referred to as helix 0 (H0), is formed in the presence of the soluble ligand inositol-1,4,5-trisphosphate [$Ins(1,4,5)P_3$] at the N terminus of the ENTH domain (amino acid residues 3-15). The ENTH domain alone and full-length epsin cause tubulation of liposomes made of brain lipids. Thus, it is believed that H0 is membrane-inserted when it is coordinated with the phospholipid phosphatidylinositol-4,5-bisphosphate [$PtdIns(4,5)P_2$], resulting in membrane deformation as well as recruitment of accessory factors to the membrane. However, formation of H0 in a real biological membrane has not been demonstrated. In the present study, the membrane structure of H0 was determined by measurement of electron paramagnetic resonance (EPR) nitroxide accessibility. H0 was located at the phosphate head-group region of the membrane. Moreover, EPR line-shape analysis indicated that no pre-formed H0-like structure were present on normal acidic membranes. $PtdIns(4,5)P_2$ was necessary and sufficient for interaction of the H0 region with the membrane. H0 was stable only in the membrane. In conclusion, the H0 region of the ENTH domain has an intrinsic ability to form H0 in a $PtdIns(4,5)P_2$-containing membrane, perhaps functioning as a sensor of membrane patches enriched with $PtdIns(4,5)P_2$ that will initiate curvature to form endocytic vesicles.

• 한국농공학회:학술대회논문집
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• 한국농공학회 1999년도 Proceedings of the 1999 Annual Conference The Korean Society of Agricutural Engineers
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• pp.169-174
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• 1999

The reclamation area of Saemangeum (Kunsan) located between 126$^{\circ}$10' -126$^{\circ}$50'E and and 35$^{\circ}$35'N -36$^{\circ}$05'N at the western coast of Korea. The construction of the 33km sea dike is building in the Saemangeum area. When the construction of the sea dike in the coastal region takes plase, there exists a certain amount of soil which is diffused by the tidal current. Behavior of the soil diffusion usually depends on its intrinsic characteristics, bathymetry, construction method and used mchinery. The amount of soil at the construction acts as a pollutant which is the cause of changing the marine environment. When the soil material is diffused , it may form a layer which obstructs the light passing into the sea and causes the extinction or alteration of the living beings on the sea bottom. The settlement of soil material could change the sea bottom deposit. The purpose of MITIGATION is to harmonize the development and the conservation of environment, to restrict environmental destruction and to reproduce the enviroment damaged by the construction in the coastal region. The purpose of this study is to find the method by which we minimize the anti-function of development in the coastal region. Tide and tidal current are calculated using a two-dimensional numerical model before the construction of sea dike in Saemangeum Bay. The numerical results are compared well with field observations. On the basis of these results, we caculated the tide and tidal current after the construction of the sea dike in order to investigate the change of the tide and tidal current after the construction of the sea dike. Moreover, we calculated the tide and tidal current after the construction of submerged breakwater in order to preserve the enviornmental condition of creature habitat . We compared the tide and tidal current before and after the construction of submerbed breakwater, to investigate the possbility of MITIGATION in the fisheries.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2008년도 추계학술대회 논문집 Vol.21
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• pp.50-50
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• 2008

ZnO has been extensively studied for optoelectronic applications such as blue and ultraviolet (UV) light emitters and detectors, because it has a wide band gap (3.37 eV) anda large exciton binding energy of ~60 meV over GaN (~26 meV). However, the fabrication of the light emitting devices using ZnO homojunctions is suffered from the lack of reproducibility of the p-type ZnO with high hall concentration and mobility. Thus, the ZnO-based p-n heterojunction light emitting diode (LED) using p-Si and p-GaN would be expected to exhibit stable device performance compared to the homojunction LED. The n-ZnO/p-GaN heterostructure is a good candidate for ZnO-based heterojunction LEDs because of their similar physical properties and the reproducibleavailability of p-type GaN. Especially, the reduced lattice mismatch (~1.8 %) and similar crystal structure result in the advantage of acquiring high performance LED devices with low defect density. However, the electroluminescence (EL) of the device using n-ZnO/p-GaN heterojunctions shows the blue and greenish emissions, which are attributed to the emission from the p-GaN and deep-level defects. In this work, the n-ZnO:Ga/p-GaN:Mg heterojunction light emitting diodes (LEDs) were fabricated at different growth temperatures and carrier concentrations in the n-type region. The effects of the growth temperature and carrier concentration on the electrical and emission properties were investigated. The I-V and the EL results showed that the device performance of the heterostructure LEDs, such as turn-on voltage and true ultraviolet emission, developed through the insertion of a thin intrinsic layer between n-ZnO:Ga and p-GaN:Mg. This observation was attributed to a lowering of the energy barriers for the supply of electrons and holes into intrinsic ZnO, and recombination in the intrinsic ZnO with the absence of deep level emission.

• Animal Bioscience
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• 제36권2호
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• pp.256-263
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• 2023

Objective: Feed molecular structures can affect its availability to gastrointestinal enzymes which impact its digestibility and absorption. The molecular spectroscopy-attenuated total reflectance Fourier transform infrared vibrational spectroscopy (ATR-FTIR) is an advanced technique that measures the absorbance of chemical functional groups on the infrared region so that we can identify and quantify molecules and functional groups in a feed. The program aimed to reveal the association of intrinsic molecular structure with nutrient supply to animals from canola feedstocks and co-products from bio-oil processing. The objective of this study was to characterize special intrinsic carbohydrate and protein-related molecular structure spectral profiles of feedstock and co-products (meal and pellets) from bio-oil processing from two source origins: Canada (CA) and China (CH). Methods: The samples of feedstock and co-products were obtained from five different companies in each country arranged by the Canola Council of Canada (CCC). The molecular structure spectral features were analyzed using advanced vibrational molecular spectroscopy-ATR-FTIR. The spectral features that accessed included: i) protein-related spectral features (Amide I, Amide II, α-helix, β-sheet, and their spectral intensity ratios), ii) carbohydrate-related spectral features (TC1, TC2, TC3, TC4, CEC, STC1, STC2, STC3, STC4, TC, and their spectral intensity ratios). Results: The results showed that significant differences were observed on all vibrationally spectral features related to total carbohydrates, structural carbohydrates, and cellulosic compounds (p<0.05), except spectral features of TC2 and STC1 (p>0.05) of co-products, where CH meals presented higher peaks of these structures than CA. Similarly, it was for the carbohydrate-related molecular structure of canola seeds where the difference between CA and CH occurred except for STC3 height, CEC and STC areas (p>0.05). The protein-related molecular structures were similar for the canola seeds from both countries. However, CH meals presented higher peaks of amide I, α-helix, and β-sheet heights, α-helix:β-sheet ratio, total amide and amide I areas (p<0.05). Conclusion: The principal component analysis was able to explain over 90% of the variabilities in the carbohydrate and protein structures although it was not able to separate the samples from the two countries, indicating feedstock and coproducts interrelationship between CH and CA.

• 대한지하수환경학회지
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• 제1권2호
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• pp.105-112
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• 1994

수리지질계에서 지질매체에 따른 오염물질들의 분산 거동을 알아보기 위하여, 흡착 오염물질로서 Sr과 비흡착 오염물질로서 Cr-EDTA를 대상으로 화강암질암에 대한 흡착 및 확산실험을 수행하였다. 분리된 광물 및 파쇄된 암석에 대한 Sr 흡착은 pH가 증가함에 따라 더불어 증가됨을 보여준다. 또한, 용액내의 NaCl의 농도가 증가하면서 이온세기가 높아지게 되면, 시료에 흡착되는 Sr의 양은 급격히 감소하였다. 분리된 광물 시료 중에서는 흑운모와 견운모가 석영, 사장석 및 칼리장석과 같은 다른 조암광물에 비하여 Sr을 훨씬 많이 흡착하였는데, 이는 일반적으로 층상 규산염광물들이 다른 조암광물들보다 비표면적과 양이온 교환능력이 훨씬 크기 때문인 것으로 판단된다. 동일한 암석인 경우, 비흡착 물질과 흡착 물질간의 고유확산계수 값에는 거의 차이가 없었다. 이는 암석의 고유확산계수가 암석과 유체 상호간의 화학반응에 거의 영향을 받지 않음을 암시한다. 또한 암석의 고유확산계수는 공극률이 커질수록 큰 값을 보여준다. 암석의 두께가 두터워질수록 전정상정류구간(pre-steady state region)에서의 실험자료와 이론적으로 계산된 곡선 사이와의 불일치 정도는 감소하는 경향을 보여주는데, 이는 사공극 확산효과(dead-end pore diffusion effect)가 암석의 두께가 두꺼워질수록 줄어듦을 의미한다.

• 한국결정성장학회:학술대회논문집
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• 한국결정성장학회 1996년도 The 9th KACG Technical Annual Meeting and the 3rd Korea-Japan EMGS (Electronic Materials Growth Symposium)
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• pp.179-200
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• 1996

The intrinsic instabilities of fluid flow occurred in the melt of the Czochralski crystal growth system Czochralski method, asymmetric flow patterns and temperature profiles in the melt have been studied by many researchers. The idea that the non-symmetric structure of the growing equipment is responsible for the asymmetric profiles is usually accepted at the first time. However further researches revealed that some intrinsic instabilities not related to the non-symmetric equipment structure in the melt could also appear. Ristorcelli had pointed out that there are many possible causes of instabilities in the melt. The instabilities appears because of the coupling effects of fluid flow and temperature profiles in the melt. Among the instabilities, the B nard type instabilities with no or low crucible rotation rates are analyzed by the visualizing experiments using X-ray radiography and the 3-D numerical simulation in this study. The velocity profiles in the Silicon melt at different crucible rotation rates were measured using X-ray radiography method using tungsten tracers in the melt. The results showed that there exits two types of fluid flow mode. One is axisymmetric flow, the other is asymmetric flow. In the axisymmetric flow, the trajectory of the tracers show torus pattern. However, more exact measurement of the axisymmetrc case shows that this flow field has small non-axisymmetric components of the velocity. When fluid flow is asymmetric, the tracers show random motion from the fixed view point. On the other hand, when the observer rotates to the same velocity of the crucible, the trajectory of the tracer show a rotating motion, the center of the motion is not same the center of the melt. The temperature of a point in the melt were measured using thermocouples with different rotating rates. Measured temperatures oscillated. Such kind of oscillations are also measured by the other researchers. The behavior of temperature oscillations were quite different between at low rotations and at high rotations. Above experimental results means that the fluid flow and temperature profiles in the melt is not symmetric, and then the mode of the asymmetric is changed when rotation rates are changed. To compare with these experimental results, the fluid flow and temperature profiles at no rotation and 8 rpm of crucible rotation rates on the same size of crucible is calculated using a 3-dimensional numerical simulation. A finite different method is adopted for this simulation. 50×30×30 grids are used. The numerical simulation also showed that the velocity and flow profiles are changed when rotation rates change. Futhermore, the flow patterns and temperature profiles of both cases are not axisymmetric even though axisymmetric boundary conditions are used. Several cells appear at no rotation. The cells are formed by the unstable vertical temperature profiles (upper region is colder than lower part) beneath the free surface of the melt. When the temperature profile is combined with density difference (Rayleigh-B nard instability) or surface tension difference (Marangoni-B nard instability) on temperature, cell structures are naturally formed. Both sources of instabilities are coupled to the cell structures in the melt of the Czochralski process. With high rotation rates, the shape of the fluid field is changed to another type of asymmetric profile. Because of the velocity profile, isothermal lines on the plane vertical to the centerline change to elliptic. When the velocity profiles are plotted at the rotating view point, two vortices appear at the both sides of centerline. These vortices seem to be the main reason of the tracer behavior shown in the asymmetric velocity experiment. This profile is quite similar to the profiles created by the baroclinic instability on the rotating annulus. The temperature profiles obtained from the numerical calculations and Fourier transforms of it are quite similar to the results of the experiment. bove esults intend that at least two types of intrinsic instabilities can occur in the melt of Czochralski growing systems. Because the instabilities cause temperature fluctuations in the melt and near the crystal-melt interface, some defects may be generated by them. When the crucible size becomes large, the intensity of the instabilities should increase. Therefore, to produce large single crystals with good quality, the behavior of the intrinsic instabilities in the melt as well as the effects of the instabilities on the defects in the ingot should be studied. As one of the cause of the defects in the large diameter Silicon single crystal grown by the