• 대한약침학회지
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• 제11권2호
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• pp.13-19
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• 2008

Objectives To investigate the therapeutic effects of intravenous cultivated wild ginseng(Panax ginseng C.A. Meyer) pharmacopuncture(CWGP) in treating patients with non-small cell lung cancer(NSCLC). Design Prospective case series. Setting This study was conducted at the East-West Cancer Center of Dunsan Oriental Hospital, Daejeon University. Patients Two non-small cell lung cancer patients. Intervention Two non-small cell lung cancer patients were injected CWGP(20mL/day) mixed with 0.9% normal saline(100mL) intravenously. Each patient received a total of 16 and 9 cycles, respectively. One cycle is composed of 14 days. Outcome Measures The effect of intravenous CWGP was measured by scanning with computed tomography(CT) after every 2 cycle and Positron emission tomography- computed tomography(PET/CT) after every 6 cycles. Response and progression was evaluated using the Response Evaluation Criteria in Solid Tumors(RECIST) Committee classification of complete response(CR), partial response(PR), progressive disease(PD) and stable disease(SD). Results They were treated with intravenous CWGP for 8 and 5 months respectively. time later, each tumor remains stable disease(SD). Conclusion These cases may give us a possibility that intravenous CWGP offers potential benefits for non-small cell lung cancer patients.

• Child Health Nursing Research
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• 제18권3호
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• pp.135-142
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• 2012

Purpose: The purpose of this study was to examine the effects of structured nursing intervention for caregivers on maintenance of intravenous (IV) infusions in infants. Methods: The structured nursing intervention was developed through the processes of interviews with nurses from pediatric wards. To identify the effects of the developed nursing intervention, a non-synchronized non-equivalent control group pretest-posttest design study was conducted with caregivers from the pediatric ward from a hospital in Seoul. Of 100 admitted infants, 50 caregivers were assigned to the intervention group and received the structured nursing intervention for maintenance of intravenous infusions in infants. The others were assigned control group and received routine care. Data were collected on patient factors, IV insertion factors, treatments, and IV related complications. The form developed for the structured nursing intervention was used by staff nurses. Results: Compared to the control group, IV insertion frequency in experimental group infants was significantly lower and IV related complications decreased (p<.05). Conclusion: These results suggest that the structured nursing intervention for caregivers on maintenance of intravenous infusions may have effects on maintenance of intravenous infusions in infants, and decreasing IV related complications. This nursing intervention can be used to improve IV related problems of admitted infants.

• 대한수의학회지
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• 제28권1호
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• pp.29-36
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• 1988

To examine the selectivity of verapamil, used in the cardiovascular diseases, on alpha-1 and alpha-2 adrenoceptor-induced pressor rsponses, effects of verapamil on alpha-adrenoceptor agonist-induced pressor responses were investigated in urethane-anesthetized rabbits, spinal rabbits, rats and pithed rats. To evaluate the effects of verapamil on each pressor response induced by norepinephrine, phenylephrine and clonidine, these agonists were previously injected into a ear vein, and then same procedures were performed 1~2 min after treatment with intravenous verapamil. The results are summarized as follows: 1. Intravenous verapamil produced dose-dependent depressor response in rabbits and rats. 2. Pressor responses to intravenous norepinephrine($10{\mu}g/kg$) and phenylphrine($30{\mu}g/kg$) were inhibited by pretreatment with intravenous verapamil in rabbits and no difference was noted between the degree of both inhibitions of the pressor response by verapamil. 3. Pressor responses to intravenous norepinephrine($3{\mu}g/kg$), phenylephrine($20{\mu}g/kg$) and clonidine ($300{\mu}g/kg$) were inhibited by pretreatment with intravenous verapamil in spinal rabbits. No difference was noted between the inhibition of norepinephrine-induced pressor response and that of phenylephrine-induced pressor response by verapamil. The inhibition of clonidine-induced pressor response by verapamil was more prominent than that of norepinephrine- or phenylephrine-induced pressor response. 4. Pressor responses to intravenous norepinephrine($3{\mu}g/kg$) and phenylephrine($10{\mu}g/kg$) were inhibited by pretreatment with intravenous verapairlil in rats and no difference was noted between the degree of both inhibitions of the pressor response by verapamil. 5. Pressor responses to intravenous norepinephrine ($3{\mu}g/kg$), phenylephrine($30{\mu}g/kg$) and clonidine($100{\mu}g/kg$) were inhibited by pretreatment with intravenous verapamil in pithed rats. No difference was noted between the inhibition of norepinephrine-induced pressor response and that of phenylephrine-induced pressor response by verapamil. The inhibition of clonidine-induced pressor response by verapamil was more prominent than that of norepinephrine- or phenylephrine-induced pressor response. These results suggest that verapamil significantly inhibits both pressor responses mediated by alpha-1 and alpha-2 adrenoceptors and the inhibition is greater in alpha-2 adrenoceptor-induced response than in alpha-1 adrenoceptor-induced one, and calcium channel takes part in the process of the pressor response mediated by alpha-1 adrenoceptors as well as alpha-2 adrenoceptors.

• 대한간호학회지
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• 제28권2호
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• pp.303-318
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• 1998

Cutaneous stimulation and distraction are independent nursing interventions used in various painful conditions, which is explained by gate control theory. This study was aimed at identifying the effect of cutaneous stimulation, distraction and combination of cutaneous stimulation and distraction on the reduction of intravenous injection pain levels of chemotherapy patients. Repeated measurement post test research design was used for one group. Fifty-three cancer patients who received intravenous chemotherapy regulary in outpatient injection rooms of D medical center and Y medical center in Taegu were studied from June 23, 1997 to July 12, 1997. First the intravenous injection pain level of the control period was measured. Second, the intravenous injection pain level of the experimental period using cutaneous stimulation was measured. Third, the intravenous injection pain level of the experimental period using distraction was messured. Fourth, the intravenous injection pain level of the experimental period using a combination of cutaneous stimulation and distraction was measured. The instruments used for this study were a visual analogue pain scale as subjective pain measurement and an objective pain behavior checklist. Analysis of data was done by use of repeated measure ANOVA, bonferni, t-test, and F-test. The results of this study were summerized as follows : 1) The first hypothesis that the subjective pain score of intraveneous injection pain in the experimental period with cutaneous stimulation will be lower than in the control period was rejected. 2) The second hypothesis that the objective pain behavior score of intravenous injection pain in the experimental period with cutaneous stimulation will be lower than in the control period was accepted(F=24.23, p=0.0001, Bornferni p<.05). 3) The third hypothesis that the subjective pain score of intraveneous injection pain in the experimental period with distraction will be lower than in the control period was rejected. 4) The fourth hypothesis that the objective pain score of intravenous injection pain in the experimental period with distraction will be lower than in the control period was accepted(F=24.23, p=0.0001, Bornferni p<.05). 5) The fifth hypothesis that the subjective pain score of intravenous injection pain in the experimental period with combination of cutaneous stimulation and distraction will be lower than in the control period was accepted(F=3.04, p=0.031, Bonferni p<.05). 6) The sixth hypothesis that the objective pain score of intravenous injection pain in the experimental period with combination of cutaneous stimulation and distraction will be lower than in the control period was accepted(F=24.23, p=0.0001, Bonferni p<.05).

• 한국정보전자통신기술학회논문지
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• 제15권6호
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• pp.506-514
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• 2022

본 논문은 정맥주사 시 발생할 수 있는 불안정 요소들을 보완하기 위해 간호사들에게 환자의 정맥주사 관련 정보를 실시간으로 제공할 수 있는 정맥주사 관리 시스템을 개발하는 것에 관한 논문이다. 정맥주사 관리시스템은 App기반의 사용자 S/W와 Web 기반의 관리자 S/W로 구성되어 있다. 사용자 S/W는 사용자가 스마트 폰, 태블릿 PC, 간호용 PDA 등의 스마트 장치를 통해 정맥주사가 필요한 환자에 대한 환자의 정보확인과 환자에게 부여된 정보 코드를 인식하여 환자를 구분하는 기능, 정맥주사 처치 이후 처치 내용과 처치 물품울 입력하고 이를 업로드 및 공유하는 기능을 제공하도록 구현했다. 관리자 S/W는 사용자 App을 통해 업로드된 정맥주사 처치 결과, 정맥주사 처치 물품에 대한 기록을 확인할 수 있고 사용자 관리 기능, 긴급공지 등록 및 관리 기능, 데이터 업로드 기능을 수행할 수 있다. 구현된 시스템은 아직 실제 병원에서 사용하고 있는 EMR 시스템에 테스트를 진행하지 않은 상태이다. 이에 추가 연구를 통해 S/W를 최적화하고 병원과의 협력을 통해 실제 환경 적용 테스트를 진행할 예정이다.

• 임상간호연구
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• 제23권3호
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• pp.361-375
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• 2017

Purpose: This study was conducted to update the existing nursing practice guideline for intravenous infusion guidelines according to the evidence-based practice guideline in South Korea. Methods: Guideline update process was performed using 22 steps according to the manuals developed by NICE and SIGN. Results: Updated nursing practice guidelines for the intravenous infusion were consisted of 23 domains and 322 recommendations. The number of recommendations in each domain were 4 for general instruction, 12 for vascular access device selection, 20 for site selection, 9 for insertion, 54 for stabilization, 21 for maintaining patency, 4 for blood sampling, 33 for exchange and removal, 28 for add-on device selection, 28, 72 for infusion related complications, 56 for infusion therapies, 7 for education, and 2 for documentation and report. There were 15.9% of A, 30.2% of B, 53.9% of C in terms of grade recommendations. A total of 178 (51.6%) recommendations were newly developed and 24 previous recommendations have been deleted. Conclusion: Updated nursing practice guideline for intravenous infusion was expected to be an evidence-based practice guideline for intravenous infusion in South Korea. This guideline is suggested to be disseminated to clinical nursing settings nationwide to improve the efficiency of intravenous infusion practice.

• 한국융합학회논문지
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• 제8권11호
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• pp.177-182
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• 2017

본 연구의 목적은 구급차의 주행조건에 따른 구급대원의 정맥로 확보 시도 횟수를 분석하여 신속한 정맥로 확보를 위한 주행 기준을 제시하고, 실험 전 후 자신감 변화를 비교해 구급대원의 정맥로 확보 자신감을 높이는데 있다. 연구기간은 2017년 5월 18일부터 27일까지이고, 연구 대상은 119 구급대원 30명(1급 응급구조사 20명, 간호사 10명)으로 구급차 주행 조건을 6가지(정차 구간, 평지 구간, 비포장 구간, 과속 방지턱 구간, 곡선 구간, 경사로 구간)로 설정하여 정맥로 확보 시도 횟수를 측정하였다. 연구결과 정차 구간과 평지 구간 주행조건에서는 시도 횟수차이가 없었고(p=.161) 비포장(p=.003), 과속 방지턱(p=.005), 곡선(p=.022), 경사로(p=.003)구간 주행조건에서는 모두 유의한 차이가 발생했다. 실험 전 후 자신감은 실험 후 자신감이 유의하게 상승(p=.000)한 것으로 나타났다. 결론적으로 주행 중 구급차 내에서의 신속한 정맥로 확보를 위해서는 차량을 정차시키거나 평지를 주행할 때 시도하는 것을 권장하며, 지속적인 훈련을 통해 정맥로 확보 자신감을 유지시켜야 할 것이다.

• 대한약침학회지
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• 제17권3호
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• pp.50-56
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• 2014

Objectives: Mountain ginseng pharmacopuncture (MGP) is an extract distilled from either mountain cultivated ginseng or mountain wild ginseng. This is the first intravenous injection of pharmacopuncture in Korea. The word intravenous does not discriminate between arteries, veins, and capillaries in Oriental Medicine, but only the vein is used for MGP. The aim of this study is to evaluate the intravenous injection toxicity of MGP through a single-dose test in Sprague-Dawley (SD) rats. Methods: Male and female 6-week-old SD rats were injected intravenously with MGP (high dosage of 20 mL/kg or low dosage of 10 mL/kg). Normal saline was injected into the rats in the control group by using the same method. After the rats has treated, we conducted clinical observations, body-weight measurements and histological observations. Results: In this study, no mortalities were observed in any of the experimental groups. Also, no significant changes by the intravenous injection of MGP were observed in the body weights, or the histological observations in any of the experimental groups compared to the control group. The lethal dose for intravenous injection of MGP was found to be over 20 mL/kg in SD rats. Conclusion: Considering that the dosage of MGP generally used each time in clinical practice is about 0.3 mL/kg, we concluded with confidence that MGP is safe pharmacopuncture.

• 대한소아치과학회지
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• 제40권1호
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• pp.28-39
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• 2013

전신마취 및 진정법은 소아 및 장애인에게 성공적 치과치료를 위해서 필수불가결하다. 이 연구의 목적은 충남장애인구강진료센터에 치과치료를 위해 시행된 전신마취와 진정법의 실태를 평가하기 위함이다. 2011년 1월부터 2012년 9월까지 전신마취, 세보플루란진정 및 정주진정을 받은 소아와 장애인 426명을 대상으로 조사분석하였으며 389명이 전신마취, 20명이 세보플루란진정 그리고 17명이 정주진정하에서 치과진료를 받았다. 전신마취의 비율이 두 진정법에 비해 높았다. 세보플루란진정은 소아환자의 외상처럼 짧고 간단한 치료에 유용하게 사용되었다. 정주진정은 공포와 불안을 가진 치과적장애환자에게 선택되었다. 세보플루란과 정주진정은 점차적으로 전신마취의 사용을 줄이고 치과적장애환자를 위한 유용한 방법이었다.

• 융합정보논문지
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• 제9권9호
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• pp.58-66
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• 2019

본 연구의 목적은 아동병원간호사의 말초정맥주입 관련 중요성 인식을 조사하고 중요성인식에 영향을 미치는 요인을 확인하기 위하여 128명의 아동병원간호사를 대상으로 시행된 서술적 조사연구로 수집된 자료를 SPSS 21.0으로 기술통계, T-test, ANOVA, Pearson's correlation 및 위계적 회귀분석을 시행하였다. 아동병원간호사의 말초정맥주입 관련 중요성 인식 중 교육이 가장 낮았고, 손위생이 가장 높았다. 결혼상태, 근무부서, 직위 및 최종학력에 따른 중요성 인식 하위영역에 부분적으로 유의한 차이가 있었고(p<.001~.046), 교육과 말초정맥주입 중요성인식 간 양의 상관관계가 있었다(p<.001). 중요성 인식에의 영향요인은 교육(${\beta}=.446$)과 근무부서(${\beta}=.247$)이었고, 변수들의 설명력은 31.0%이었다(p<.001). 본 연구결과는 반복 연구 후 아동병원간호사의 말초정맥주입 중요성 인식 관련 교육프로그램의 기초자료로 활용될 수 있다.