• IMMUNE NETWORK
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• v.4 no.3
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• pp.176-183
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• 2004

Background: Human seminal plasma (HSP)-induced hypersensitivity is one of the serious complications with sexual intercourse. The clinical manifestations of HSP-induced hypersensitivity may be related to the release of vasoactive mediators from mast cell induced by HSP. It has recently been reported that HSP modulates immune systems and induces mast cell degranulation and histamine release from rat peritoneal mast cells (RPMC). Ketotifen and disodium cromoglycate (DSCG), anti-asthmatic and anti-allergic drugs, have a role of mast cell stabilization and inhibit mast cell-induced leukocyte rolling and adhesion. But the inhibitory agents of HSP-induced mast cell activation are unknown. This study was performed to investigate the effects of DSCG and ketotifen on the HSP-induced mast cell activation. Methods: For this, influences of DSCG and ketotifen on the human seminal plasma-induced degranulation, histamine release and morphological changes of RPMC were observed. Results: The mast cell degranulation and histamine release of RPMC by HSP were induced in a dose-dependent fashion. The HSP-induced cytomorphological changes such as swelling, intracellular vacoules, and interrupted cell boundary were significantly inhibited by pretreatment with DSCG or ketotifen. DSCG and Ketotifen inhibited the HSP-induced degranulation and histamine release from RPMC. Conclusion: From the above results, it is suggested that DSCG and ketotifen have a inhibitory effect of the HSP-induced mast cell activation. DSCG and ketotifen may be used for treatment of HSP-induced hypersensitivity.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.67 no.4
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• pp.595-599
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• 2018

Interruption system with the transformer type superconducting fault current limiter(TSFCL) is proposed in this paper. The interruption system with a TSFCL is a technology that it maximizes the interruption function of a mechanical DC circuit breaker using a transformer and a superconducting fault current limiter. By a TSFCL, the system limits the fault current till the breakable current range in the fault state. Therefore, the fault current could be cut off by a mechanical DC circuit breaker. The Interruption system with a TSFCL were designed using PSCAD/EMTDC. In addition, the Interruption system with a TSFCL was applied to the DC test circuit to analyze characteristics of a current-limiting and a interruption operation. The simulation results showed that the Interruption system with a TSFCL interrupted the fault current in a stable when a fault occurred. Also, The current-limiting rate of the Interruption system with a TSFCL was approximately 69.55%, and the interruption time was less than 8 ms.

• KEPCO Journal on Electric Power and Energy
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• v.2 no.3
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• pp.425-431
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• 2016

Supply Capability of the generator, if the maximum demand occurs, refers to the maximum power that can be stably supplied and it is possible to maintain stable power supply to be greater than actual load. However, unexpected power demand and reduction in supply Capability due to stop of unexpected generator in operation can temporarily make a big chaos in power system. In fact, due to a lack of power supply Capability in the country, enforced emergency load adjustment to the September 15, 2011, the circulation power outage has occurred in several cities. As the result, interrupted operation of the elevator and stopped hospital medical equipment led to a great deal of trouble to people's lives, causing a social problem. At that time, it was found that a failed frequency control because of smaller actual supply Capability than that of predicted. The difference was about 1,170 MW with Gas turbine power plant. By accurately calculating the generator supply capability, we can not only grasp the power reserve rate, but also correspond to the time of power supply instability.

• International Journal of Highway Engineering
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• v.17 no.4
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• pp.117-126
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• 2015

PURPOSES : This study aims to investigate the direct and indirect influence areas from incidents on urban interrupted roadways and to develop traffic management strategies for each influence area. METHODS : Based on a literature review, various traffic management strategies for certain incidents were collected. In addition, the relationship between the measure of effectiveness and the characteristics of incidents was explored using an extensive simulation study. RESULTS : From the simulation studies, traffic delays increased as the number of lane closures increased, and the impact of lane closures was reduced to the direction upstream from the incident site. However, the magnitude of the delay change depended on the degree of saturation. Using these characteristics, the direct and indirect influence areas resulting from incidents were defined, and traffic management strategies were established for each direct and indirect influence area and for each level of incident. CONCLUSIONS: The results of this study will contribute to the improvement of national traffic safety by preventing secondary incidents and by effective adaptation to incident events.

• International Journal of Knowledge Content Development & Technology
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• v.7 no.4
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• pp.51-69
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• 2017

Availability, awareness and use of electronic resources provide access to authoritative, reliable, accurate and timely access to information. The use of electronic information resources (EIRs) can enable innovation in teaching and increase timeliness in research of postgraduate students which will eventual result into encouragement of the expected research-led enquiry in this digital age. The study adopted a descriptive survey design. Samples of 300 of postgraduate students within seven out 13 Faculties were randomly selected. Data were collected using questionnaire designed to elicit response from respondents and data were analyzed using descriptive statistics methods percentages, mean, and standard deviation. Results indicated that internet was ranked most available and used in the university. Low level of usage of electronic resources, in particular, full texts data bases is linked to a number of constraints: Interrupted power supply was ranked highest among other factors as speed and capacity of computers, retrieval of records with high recall and low precision, retrieving records relevant to information need, lack of knowledge of search techniques to retrieve information effectively, non possession of requisite IT skills and problems accessing the internet. The study recommended that usage of electronic resources be made compulsory, intensifying awareness campaigns concerning the availability, training on use of electronic resources and the problem of power outage be addressed.

• Progress in Superconductivity and Cryogenics
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• v.19 no.4
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• pp.40-44
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• 2017

This paper analyzed the fault current limiting characteristics of the previously proposed transformer superconducting fault current limiter (TSFCL) interruption system according to its transformer type. The TSFCL interruption system is an interruption technology that combines a TSFCL, which uses a transformer and a superconductor, and a mechanical DC circuit breaker. This technology first limits the fault current using the inductance of the transformer winding and the quench characteristics of the superconductor. The limited fault current is then interrupted by a mechanical DC circuit breaker. The magnitude of the limited fault current can be controlled by the quench resistance of the superconductor in the TSFCL and the turns ratio of the transformer. When the fault current is controlled using a superconductor, additional costs are incurred due to the cooling vessel and the length of the superconductor. When the fault current is controlled using step-up and step-down transformers, however, it is possible to control the fault current more economically than using the superconductor. The TSFCL interruption system was designed using PSCAD/EMTDC-based analysis software, and the fault current limiting characteristics according to the type of the transformer were analyzed. The turns ratios of the step-up and step-down transformers were set to 1:2 and 2:1. The results were compared with those of a transformer with a 1:1 turns ratio.

• Journal of Life Science
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• v.8 no.3
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• pp.285-293
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• 1998

We have cloned an internal fragment of the putative transoisase gene of MLE in the silkworm, Bombyx mori, using PCR method with degenerative oligonucleotide primers designed to represent regions of amino acids encoding transposase. The resulting PCR clone, designed as BmoMAR, cords a partial ORF(152 a.a.) of MLE in which interrupted by five stop codons, and the sequence of its deduced amino acids showed 37% homology with Mos1, an active mariner, from Drosophila mauritiana. Furthermore, the BmoMAR exhibits nucleotide and amino acid homology with 59% and 37% from Apis mellifera and D. mauritiana 7.9 clone, respectively. This result strongly that a MLE is present in the genome of B. mori.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.36 no.2
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• pp.139-146
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• 2000

Cavitation can occur in pipes when liquid is moving at high velocity, especially at pittings where the smooth bore of the pipe is interrupted. The effect is usually to produce pitting on the downstream side of the turbulence. However, stress corrosion cracking behavior under cavitation erosion-corrosion was neatly unknown. In this study, therefore, some were investigated of stress corrosion cracking behavior, others were stress corrosion cracking behavior under cavitation erosion-corrosion of water injection. And datas obtained as the results of experiment were compared between the two. Mainresult obtained are as follows: 1) Stress corrosion cracking growth rate of heat affected zone under cavitation erosion-corrosion becomes most rapid, and stress intensity factor $K_1$becomes most high. 2) Stress corrosion cracking growth mechanism by cavitation erosion-corrosion is judgement on the strength of the film rupture model and the tunnel model. 3) The range of potential as passivation of heat affected zone is less noble than that of base metal, and that value is smaller. 4) Corrosion potential under cavitation erosion-corrosion in loaded stress is less noble than that of stress corrosion, and corrosion current density is higher.

• BMB Reports
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• v.44 no.10
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• pp.653-658
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• 2011

Sclerotinia sclerotiorum fungus has three endoxylanases induced by wheat bran. In the first part, a partial xylanase sequence gene (90 bp) was isolated by PCR corresponding to catalytic domains (${\beta}5$ and ${\beta}6$ strands of this protein). The high homology of this sequence with xylanase of Botryotinia fuckeliana has permitted in the second part to amplify the XYN1 gene. Sequence analysis of DNA and cDNA revealed an ORF of 746 bp interrupted by a 65 bp intron, thus encoding a predicted protein of 226 amino acids. The mature enzyme (20.06 kDa), is coded by 188 amino acid (pI 9.26). XYN1 belongs to G/11 glycosyl hydrolases family with a conserved catalytic domain containing $E_{86}$ and $E_{178}$ residues. Bioinformatics analysis revealed that there was no Asn-X-Ser/Thr motif required for N-linked glycosylation in the deduced sequence however, five O-glycosylation sites could intervene in the different folding of xylanses isoforms and in their secretary pathway.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.26 no.11
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• pp.2336-2341
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• 2002

When WC and group IV elements are added to Ti(C,N)-Ni cermet, microstructures of the cermet is changed. The change effects directly on the property of the material. In this study, the amount of WC and group IV elements of Ti(C,N) cermet tool was investigated. The composition of WC was changed from 5 to 20wt% to determine the effect of WC on the cutting performance of cermet tool. The more WC was added, the longer the tool life of the cermet tool was. The cermet with lwt% ZrC and l4wt% WC showed the best cutting performance among the investigated cermet tools. The cutting performance of cermet cutting tools suggests the possibility in interrupted cutting for reliability test experimentation was performed repeatedly with $Ti(C_{0.7},N_{0.3})- l4WC-1ZrC-20Ni$ cermet tool machining SCM440. The flank wear of cermet cutting tool at given time condition is suitable for Normal distribution and Log normal distribution by Chi squared test.