• Nuclear Engineering and Technology
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• 제42권1호
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• pp.109-114
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• 2010

Bioassay data analysis software (BiDAS-2007) has been developed by KAERI, which adds several new functions to its previous version. New functions of the BiDAS-2007 computer code enable the user not only to do a simultaneous analysis by using two or more types of bioassay for the best internal dose evaluation, but also to do a continual internal dose evaluation from a change of the internal exposure conditions such as an intake type (acute, chronic), an intake pathway (inhalation, ingestion), an absorption type (Type F, M, S), and a particle size (AMAD, activity median aerodynamic diameter), and also to estimate the intakes in various conditions of an internal exposure at a time. The values calculated by the BiDAS-2007 code are consistent and in good agreement with those values by IMIE-2004 code by Berkovski and IMBA code by Birchall. The BiDAS-2007 computer code is very useful and user-friendly to estimate the radionuclide intakes and committed effective doses of a radiation worker.

• Environmental Analysis Health and Toxicology
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• 제31권
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• pp.1.1-1.13
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• 2016

Objectives To investigate the accuracy and scientific validity of the current very low risk factor for hereditary diseases in humans following exposures to ionizing radiation adopted by the United Nations Scientific Committee on the Effects of Atomic Radiation and the International Commission on Radiological Protection. The value is based on experiments on mice due to reportedly absent effects in the Japanese atomic bomb (A-bomb) survivors. Methods To review the published evidence for heritable effects after ionising radiation exposures particularly, but not restricted to, populations exposed to contamination from the Chernobyl accident and from atmospheric nuclear test fallout. To make a compilation of findings about early deaths, congenital malformations, Down's syndrome, cancer and other genetic effects observed in humans after the exposure of the parents. To also examine more closely the evidence from the Japanese A-bomb epidemiology and discuss its scientific validity. Results Nearly all types of hereditary defects were found at doses as low as one to 10 mSv. We discuss the clash between the current risk model and these observations on the basis of biological mechanism and assumptions about linear relationships between dose and effect in neonatal and foetal epidemiology. The evidence supports a dose response relationship which is non-linear and is either biphasic or supralinear (hogs-back) and largely either saturates or falls above 10 mSv. Conclusions We conclude that the current risk model for heritable effects of radiation is unsafe. The dose response relationship is non-linear with the greatest effects at the lowest doses. Using Chernobyl data we derive an excess relative risk for all malformations of 1.0 per 10 mSv cumulative dose. The safety of the Japanese A-bomb epidemiology is argued to be both scientifically and philosophically questionable owing to errors in the choice of control groups, omission of internal exposure effects and assumptions about linear dose response.

• Journal of Radiation Protection and Research
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• 제34권1호
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• pp.37-42
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• 2009

국내 원전에서는 원전종사자의 내부피폭 방사능을 측정하기위해 전신계측기를 이용하고 있다. 이 전신계측기는 Sodium Iodide를 이용한 섬광검출기로서 짧은 시간에 종사자가 보유한 방사성핵종과 방사능을 측정하는 기능을 가지고 있다. 그런데 종사자의 신체표면에 부착된 오염과 내부에 침적된 오염을 구분하지 못하기 때문에 방사선계측 과정에서 종종 오류를 범할 가능성이 있으며, 이 경우 내부피폭선량은 매우 보수적으로 과대평가된다. 이러한 문제점을 개선하고자 종사자의 인체 내부와 외부 표면오염을 구분하고, 보다 체계적으로 오염부위를 확인할 수 있도록 전신계측기와 인체모형 팬텀을 이용한 방사능 계측실험을 수행하였다. 또한 원전에서 발생하는 주요 핵종의 신체내 침적위치를 고려하여 전신계측기의 최적 방사능 측정모드를 결정하는 실험을 수행하였다. 이러한 방사능 측정 실험결과를 근거로 원전종사자의 내부방사능 측정과 선량평가 절차를 개선하였다. 이에따라 보다 정확한 전신계측프로그램의 적용으로 내부피폭선량의 보수적 평가를 방지할 수 있을 것으로 기대된다.

• 한국방사선학회논문지
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• 제10권7호
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• pp.489-494
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• 2016

사이클로트론에서 발생되는 핵반응은 불필요한 중성자를 발생시키며, 이로 인해 주변 물질들이 방사화되게 된다. 방사화된 물질은 방사선피폭의 원인으로, 공기가 방사화 되었을 경우 인체에 흡입되어 내부피폭을 발생 시킨다. 이에 본 연구에서는 16.5 MeV의 초소형 사이클로트론의 운영에 따른 내부 공기의 방사화를 분석하고자 하였다. 실험결과 초소형 사이클로트론의 핵반응으로 발생되는 방사화는 종사자에게 매우 낮은 내부피폭을 발생시키는 것을 확인할 수 있었으며, 방사화로 인하여 발생된 방사능을 법적 기준치와 비교하여 보았을 때 기준치 이하로 법적 관리의 대상에서 제외 될 수 있음을 알 수 있었다. 하지만, 사이클로트론의 에너지가 높아짐에 따라 내부피폭의 위험성은 더욱 높아질 우려가 있으며, 이에 따라 국내에 정립 되어 있지 않는 방사선 관련 시설의 환기설비에 대한 기준이 필요할 것으로 사료되었다.

• 한국산업보건학회지
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• 제29권2호
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• pp.167-175
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• 2019

Objectives: The purpose of this study was to evaluate airborne radon and thoron levels and estimate the effective doses of workers who made household goods and mattresses using monazite. Methods: Airborne radon and thoron concentrations were measured using continuous monitors (Rad7, Durridge Company Inc., USA). Radon and thoron concentrations in the air were converted to radon doses using the dose conversion factor recommended by the Nuclear Safety and Security Commission in Korea. External exposure to gamma rays was measured at the chest height of a worker from the source using real-time radiation instruments, a survey meter (RadiagemTM 2000, Canberra Industries, Inc., USA), and an ion chamber (OD-01 Hx, STEP Co., Germany). Results: When using monazite, the average concentration range of radon was $13.1-97.8Bq/m^3$ and thoron was $210.1-841.4Bq/m^3$. When monazite was not used, the average concentration range of radon was $2.6-10.8Bq/m^3$ and the maximum was $1.7-66.2Bq/m^3$. Since monazite has a higher content of thorium than uranium, the effects of thoron should be considered. The effective doses of radon and thoron as calculated by the dose conversion factor based on ICRP 115 were 0.26 mSv/yr and 0.76 mSv/yr, respectively, at their maximum values. The external radiation dose rate was $6.7{\mu}Sv/hr$ at chest height and the effective dose was 4.3 mSv/yr at the maximum. Conclusions: Regardless of the use of monazite, the total annual effective doses due to internal and external exposure were 0.03-4.42 mSv/yr. Exposures to levels higher than this value are indicated if dose conversion factors based on the recently published ICRP 137 are applied.

• Journal of Radiation Protection and Research
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• 제39권1호
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• pp.1-6
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• 2014

원전에서는 방사성핵종의 체내 섭취에 따른 작업종사자의 내부 방사능을 측정하기 위하여 전신계측기(WBC)를 이용하고 있다. 이 계측기는 인체 내 방사성핵종의 침적위치를 고려하여 다양한 측정 모드를 선택하여 측정할 수 있으나, 대부분 전신 모드를 적용하고 있다. 그런데 전신 모드를 적용한 내부방사능 측정값은 WBC 측정 모드 중에서 가장 보수적인 값을 나타내는 특성이 있고, 따라서 내부피폭 방사선량이 과대평가되는 문제점이 있다. 이러한 문제점을 해결하기 위해 WBC, 팬텀, 표준 방사선원을 이용하여 WBC의 측정 모드별 방사능측정 실험을 수행하였다. 이 결과에 대해 통계적 분석방법을 적용하여 WBC의 상부 및 하부 검출기 계측비율에 따라 WBC의 측정 모드를 선정할 수 있는 정량적인 기준을 제시하였다.

• Nuclear Engineering and Technology
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• 제53권1호
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• pp.351-356
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• 2021

Korean nuclear power plants (NPPs) have various radiation protection programs to attain radiation exposure as low as reasonably achievable (ALARA). In terms of ALARA, this paper provides a comprehensive overview of administrative dose control for occupationally-exposed workers in Korean NPPs. In addition to dose limits, administrative dose constraints are implemented to resolve an inequity of radiation exposure in which some individuals in NPPs receive relatively higher doses than others. Occupational dose constraints in Korean NPPs are presented in this paper with the background of how those values were determined. For pressurized water reactors, 80% and 90% of the annual average limit for an effective dose, 20 mSv/y, are set as the primary and secondary dose constraints, respectively. Pressurized heavy water reactors (PHWRs) have also established the primary and secondary dose constraints corresponding to 70% and 80% of the effective dose limit, and additional constraints for tritium concentration are provided to control internal exposure in PHWRs. Follow-up measures for exceeding these administrative dose constraints are also introduced compared to exceeding the dose limits. Finally, analysis results of dose distributions show how the implementation of administrative dose constraints impacted the occupational dose distributions in Korean NPPs during the years 2009-2018.

• 식품보건융합연구
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• 제4권3호
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• pp.1-5
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• 2018

In today's technological development of human society more and more influence on the lives of biological organisms different electromagnetic radiation. Therefore, the study and analysis of the mechanisms of their effects is an urgent task. The purpose of research - the study of the primary mechanisms of interaction of photons of optical radiation with the structures of biological objects, using the laws of quantum mechanics and biophysics. Photobiological basis of the mechanism of action of EMR optical range is the energy absorption of light quanta (photons) by atoms and molecules of biological structures (law Grotgus-Draper), which resulted in the formation of electronically excited states of these molecules with the transfer of photon energy (internal photoeffect). This is accompanied by electrolytic dissociation and ionization of biological molecules. The degree of manifestation of photobiological effects in the body depends on the intensity of the optical radiation, which is inversely proportional to the square of the distance from the source to the irradiated surface. Accordingly, in practice, determine not the intensity and irradiation dose at a certain distance from the source of exposure by the exposure time.

• 혜화의학회지
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• 제8권1호
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• pp.403-424
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• 1999

To evaluate the antitumor activity, antimetastatic and radioprotective effects of Kamisasammaekmundongtang(KSMT), studies were done experimentally. The results were obtained as follows: 1. In cytotoxicity against P388, A549 and B16-F10, KSMT was not showed satisfiable cytotoxicity as compared with control. 2. In Inhibitory effect on activity of DNA topoisomerase I, KSMT has strong inhibitory effect. 3. The inhibitory effect on adhesion of A549 to complex extracellular matrix was significantly increased at 0.5mg/ml, 1mg/ml of KSMT. 4. The T/C% was 122 in KSMT treated group in S-180 bearing ICR mice. 5. In antiangiogenetic effect on CAM assay, inhibitory rate was 33% in KSMT treated group. 6. In pulmonary colonization assay, a number of colonies in the lungs were decreased significantly in KSMT treated group as compared with control group. 7. By FACS analysis of splenic leukocyte after exposure to radiation by linear accelerator, T-helper cell, B cell and macrophage in KSMT treated group were significantly increased while splenocytes were decreased in control group. 8. In histological changes of jejunum of $Bald{\setminus}C$ mice after exposure to radiation by linear accelerator, exclusion and fusion of villi were decreased as compared with control group. But in duodenum and ileum, exclusion and fusion of villi were not decreased as compared with control group. 9. WBC, PLT were increased in KSMT treated group as compared with control group after exposure to radiation by linear accelerator, but the increasing effect was not significant. Above results suggest that KSMT may be useful in prevention of cancer metastasis and protection from damage by radiotherapy. But the further study of KSMT would be demanded.

• 방사선산업학회지
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• 제18권2호
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• pp.101-107
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• 2024

Rapid screening for internal contamination by alpha- and beta-emitting radionuclides is essential in situations involving radiation workers or radiation accidents. This study focused on the use of urine samples and liquid scintillation counting to quickly and accurately assess contamination. Calibration of the alpha and beta detection areas ensured precise measurement results. The major radionuclides recommended for surveillance during accidents were also considered. This study evaluated the effectiveness of the method by examining various parameters, including the limit of detection, linearity, sensitivity, selectivity, accuracy, ruggedness, and blind test sample analysis. The liquid scintillation counting method is an effective tool for screening urinary samples to detect alpha- and beta-emitting radionuclides, particularly during radiation emergencies, despite some limitations in precision.