• The Korean Journal of Nuclear Medicine Technology
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• v.26 no.2
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• pp.43-47
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• 2022

Purpose Radioimmunoassay implement quality control by systematizing the internal quality control system for quality assurance of test results. This study aims to contribute to the quality assurance of radioimmunoassay results and to implement systematic quality control by measuring the average CV of internal quality control and external quality control by plenty of institutions for reference when setting the laboratory's own acceptable range. Materials and Methods We measured the average CV of internal quality control and the bounce rate of more than 10.0% for a total of 42 items from October 2020 to December 2021. According to the CV result, we classified and compared the upper group (5.0% or less), the middle group (5.0~10.0%) and the lower group (10.0% or more). The bounce rate of 10.0% or more was compared by classifying the item of five or more institutions into tumor markers, thyroid hormones and other hormones. The average CV was measured by the overall average and standard deviation of the external quality control results for 28 items from the first quarter to the fourth quarter of 2021. In addition, the average CV was measured by the overall average and standard deviation of the proficiency results between institutions for 13 items in the first half and the second half of 2021. The average CV of internal quality control and external quality control was compared by item so we compared and analyzed the items that implement well to quality control and the items that require attention to quality control. Results As a result of measuring the precision average of internal quality control for 42 items of six institutions, the top group (5.0% or less) are Ferritin, HGH, SHBG, and 25-OH-VitD, while the bottom group (≤10.0%) are cortisol, ATA, AMA, renin, and estradiol. When comparing more than 10.0% bounce rate of CV for tumor markers, CA-125 (6.7%), CA-19-9 (9.8%) implemented well, while SCC-Ag (24.3%), CA-15-3 (26.7%) were among the items that require attention to control. As a result of comparing the bounce rate of more than 10.0% of CV for thyroid hormones examination, free T4 (2.1%), T3 (9.3%) showed excellent performance and AMA (39.6%), ATA (51.6%) required attention to control. When comparing the bounce rate of 10.0% or more of CV for other hormones, IGF-1 (8.8%), FSH (9.1%), prolactin (9.2%) showed excellent performance, however estradiol (37.3%), testosterone (37.7%), cortisol (44.4%) required attention to control. As a result of measuring the average CV of the whole institutions participating at external quality control for 28 items, HGH and SCC-Ag were included in the top group (≤10.0%), however ATA, estradiol, TSI, and thyroglobulin included in bottom group (≥30.0%). Conclusion As a result of evaluating 42 items of six institutions, the average CV was 3.7~12.2% showing a 3.3 times difference between the upper group and the lower group. Cortisol, ATA, AMA, Renin and estradiol tests with high CV will require continuous improvement activities to improve precision. In addition, we measured and compared the overall average CV of the internal quality control, the external quality control and the proficiency between institutions participating of six institutions for 41 items excluding HBs-Ab. As a result, ATA, AMA, Renin and estradiol belong to the same subgroup so we require attention to control and consider setting a higher acceptable range. It is recommended to set and control the acceptable range standard of internal quality control CV in consideration of many things in the laboratory due to the different reagents and instruments, and the results vary depending on the test's proficiency and quality control materials. It is thought that the accuracy and reliability of radioimmunoassay results can be improved if systematic quality control is implemented based on the set acceptable range.

• Journal of Korean Society for Quality Management
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• v.32 no.3
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• pp.109-125
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• 2004

This paper deals with an optimal process control problem in production of hull structural steel plate with high defective rate. The main quality characteristic(dependent variable) is the internal quality(defect) of plates and is dependent on process parameters(independent variables). The dependent variable(quality characteristics) has three categorical ordinal data and there are 35 independent variables(29 continuous variables and 6 categorical variables). In this paper, we determine the main factors and to develop the mathematical model between internal quality predicted probabilities and the main factors. Secondly, we find out the optimal process condition of main factors through analysis of variance(ANOVA) using simulation. We consider three models to obtain the main factors and the optimal process condition: linear, quadratic, error models.

• Tuberculosis and Respiratory Diseases
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• v.86 no.2
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• pp.111-119
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• 2023

Background: The objective of this study was to investigate whether alcohol consumption might affect the quality of life (QOL), depressive mood, and metabolic syndrome in patients with obstructive lung disease (OLD). Methods: Data were obtained from the Korean National Health and Nutrition Examination Survey from 2014 and 2016. OLD was defined as spirometry of forced expiratory volume in 1 second/forced vital capacity <0.7 in those aged more than 40 years. QOL was evaluated using the European Quality of Life Questionnaire-5D (EQ-5D) index. Patient Health Questionnaire-9 (PHQ-9) was used to assess the severity of depressive mood. Alcohol consumption was based on a history of alcohol ingestion during the previous month. Results: A total of 984 participants with OLD (695 males, 289 females, age 65.8±9.7 years) were enrolled. The EQ-5D index was significantly higher in alcohol drinkers (n=525) than in non-alcohol drinkers (n=459) (0.94±0.11 vs. 0.91±0.13, p=0.002). PHQ9 scores were considerably lower in alcohol drinkers than in non-alcohol drinkers (2.15±3.57 vs. 2.78±4.13, p=0.013). However, multiple logistic regression analysis showed that alcohol consumption was not associated with EQ-5D index or PHQ-9 score. Body mass index ≥25 kg/m², triglyceride ≥150 mg/dL, high-density lipoprotein <40 mg/dL in men and <50 mg/dL in women, and blood pressure ≥130/85 mm Hg were significantly more common in alcohol drinkers than in non-alcohol drinkers (all p<0.05). Conclusion: Alcohol consumption did not change the QOL or depressive mood of OLD patients. However, metabolic syndrome-related factors were more common in alcohol drinkers than in non-alcohol drinkers.

• Journal of Animal Science and Technology
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• v.54 no.1
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• pp.43-49
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• 2012

This study was carried out to investigate the effects of age of laying hens and grade of shell abnormality on internal egg quality. At each week, 1,000 eggs were randomly selected from 21,000 eggs laid by Hy-Line hens (100,000 birds) aged from 56 to 62 wk. The samples were divided into normal and externally abnormal eggs by an official egg grader. Then, egg quality including egg weight, egg white height, Haugh unit and yolk color was evaluated from each normal and abnormal eggs. The production rate of externally normal and abnormal eggs was 81.22 and 18.78%, respectively. No difference found in the production rate by the increase of hen's age, but Haugh unit of eggs from hens of 60-wk-old was higher (p<0.05) than that of 56-wk-old. When the same age groups were compared, egg white height and Haugh unit were lower in eggs which were externally abnormal. When the grade of abnormality increased, egg white height and Haugh unit were decreased further (p<0.05). Among the externally abnormal eggs, malformation showed the lowest Haugh unit. In conclusion, the shell abnormality of eggs laid by hens aged 56 to 62 wk was closely related with internal egg quality. Therefore, the grading external egg quality in the present egg grading system is directly related with the internal egg freshness.

• Tuberculosis and Respiratory Diseases
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• v.45 no.3
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• pp.630-635
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• 1998

Lung volume reduction surgery, resecting the most severely affected regions of emphysema, was designed to improve quality of life for selected patients with severe emphysema We report a case of a 72 year old severe emphysema patient who received bilateral lung volume reduction surgery and showed marked improvement of quality of life and lung function.

• Herbal Formula Science
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• v.21 no.2
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• pp.173-180
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• 2013

Objectives : A 55-year-old male patient whose symptoms were not improved by western drugs(including steroids) was hospitalized in Korean medical hospital for 22 days. Methods : This patient was diagnosed as Han-po-yeol(寒包熱) and treated with herbal decoctions, acupuncture, and moxibustion. And he answered the quality of life questionnaire for adult Korean asthmatics (QLQAKA) at 1st, 15th, and 22th day of hospitalization. Results : After 2 weeks herbal medical treatment, score of QLQAKA was increased by 0.53 point. Conclusion : This result suggest that Korean medical treatment has the potential for asthma patients who did not responded to western drugs.

• The Journal of Internal Korean Medicine
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• v.37 no.5
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• pp.822-830
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• 2016

Objective: To report the effect of Gamiguibi-tang (加味歸脾湯) as a treatment for insomnia. Methods: An insomnia patient who scored 27 points for her insomnia severity index was enrolled in this study. She received oriental treatment with herbal medication (Gamiguibi-tang), acupuncture, and moxibustion for 1 month. Results: After treatment, sleep duration and sleep quality were improved. After the patient had taken Gamiguibi-tang, her score for the Pittsburgh Sleep Quality Index (PSQI) decreased from 21 to 9, and associated symptoms were also improved without taking sleeping pills. Conclusions: Gamiguibi-tang is effective for the treatment of insomnia. More clinical data and studies are required in patients suffering from insomnia.

• Educational Technology International
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• v.13 no.1
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• pp.145-173
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• 2012

The purpose of this study is to develop collaboration scripts as an instructional means to facilitate argumentation in computer-supported collaborative learning, and to analyze their effects. To develop collaboration scripts for argumentation, researchers used activity theory as a conceptual framework and refined the design principles by design-based research. Using LAMS, collaboration scripts for argumentation were developed based on the ArgueGraph. To examine their effects, 72 participants were divided into two groups by internal scripts and randomly allocated to one of three external scripts. Applying mixed methods, researchers analyzed argumentation competence related to the cognitive aspect, examined self-efficacy related to the motivational aspect, and identified the factors influencing collaborative learning processes and outcomes. Researchers found that the internal script is a critical factor to determine the dimensions, degrees, and duration of improvement in argumentation competence. That is, learners with higher internal scripts improved highly in the quality of single arguments, while learners with lower internal scripts improved continuously in the quality of argumentation sequences. The effects of the external scripts varied with the internal script levels and supporting periods. Besides, collaboration scripts for argumentation had positive effects on learners' self-efficacy, and learners with higher internal scripts had better self-efficacy. The factors influencing collaborative learning processes and outcomes showed different results depending on the learning context. Therefore, when scripting learner's interaction in CSCL, researchers should design the scripts adaptable to a natural context of activities.

• Journal of Technology Innovation
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• v.5 no.2
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• pp.178-206
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• 1997

This study is concerned with the importance of TQM factors, and their characteristics on quality management. Key aspects of management commitment and ploicy, quality department and communication, equipment and material management, training, and employee relations etc. in TQM measurement, their theoretical background and employee perception about their importance intensively are investigated. In the importance of TQM, quality department and communication, quality and reporting, and rpoduction process management appeared to have a low rating while management commitment and quality policy, internal customer and supplier have a comparatively high value. And some perception for these factor showed difference between production and non-production department; internal customer and supplier, production process management, and employee relation.

• Journal of Korea Port Economic Association
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• v.26 no.4
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• pp.122-146
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• 2010

This purpose of this study is to analyze the causal relation among constituent concepts and verify the relation among internal marketing, service quality and customer satisfaction in shipping companies. To achieve the goal of this study, the author studied literatures on internal marketing, service quality and customer satisfaction, and carried out a survey targeting people working for shipping companies and international logistics freight forwarders to make an empirical analysis. The results are as follows. It was confirmed that education and training, reward system, empowerment among internal marketing elements of a shipping company have a positive effect on the service quality and customer satisfaction of the shipping company, and the service quality of a shipping company also has a positive effect on customer satisfaction. As it can be known from these results, it would be necessary to concentrate on internal marketing of a shipping company in order to increase service quality and customer satisfaction.