• 대한한방내과학회지
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• 제34권4호
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• pp.438-446
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• 2013

The purpose of this study is to report the clinical effects of modified Seogakjihwang-tang on a patient who had headache and memory disorder after traumatic brain injury, which were considered as the result of blood stasis. The patient had headache and memory disorder after traumatic brain injury and treated with modified Seogakjihwang-tang three times a day for 60days. As a result, the numerical rating scale and pain rating score of headache decreased and the scores of mini-mental state examination-Korea, the Korean version of Montreal cognitive assessment and the mini-memory test increased during treatment with modified Seogakjihwang-tang. Therefore, this case supports a possibility that modified Seogakjihwang-tang might be an effective treatment to patients with headache and memory disorder after traumatic brain injury.

• 방송공학회논문지
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• 제16권2호
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• pp.339-349
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• 2011

고해상도 비디오에 대한 압축 성능 향상을 위해 내부 연산 비트 깊이를 증가시키는 IBDI (Internal Bit Depth Increase) 기법은 괄목할 만한 부호화 효율 증가 이득을 얻을 수 있었지만, 참조 영상을 저장하기 위해 소요되는 내부 메모리가 증가하는 문제가 발생한다. 따라서 IBDI 기법의 부호화 효율은 유지하면서 내부 메모리 증가 문제를 해결하기 위해 메모리 압축 기법이 제안되었다. 기존 메모리 압축 기법은 영상의 각 수행블록마다 일정량의 부가정보를 이용하여 메모리 압축을 수행함으로써, 부호화 효율은 유지하면서 내부 메모리를 성공적으로 줄일 수 있었다. 하지만 각각의 수행블록마다 발생하는 부가정보에 의해 메모리 압축 성능이 제한되는 한계가 존재한다. 따라서 본 논문에서는 기존 메모리 압축 방법의 한계를 극복하기 위해, 발생하는 부가정보량을 크게 줄일 수 있도록 선택적 수행블록 병합을 이용한 메모리 압축 방법을 제안하였다. 제안 방법을 통해 부호화 효율을 기존 메모리 압축 방법과 동일하게 유지하면서 메모리 압축에 의해 발생하는 부가정보량은 크게 감소하는 이득을 얻을 수 있었다.

• 한국콘텐츠학회논문지
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• 제8권5호
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• pp.72-81
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• 2008

고성능 DSP는 보통 캐쉬와 내부 메모리를 지원한다. 이러한 고성능 DSP에 멀티미디어 스트림 응용을 최적화하여 구현하고자 하는 경우에는, DSP 가 지원하는 캐쉬와 내부 메모리를 효율적으로 잘 활용하여야 한다. 본 논문에서는 2단계 레벨 캐쉬 구조 및 내부 메모리 구성을 지원하는 고성능 DSP인 TMS320C6000 시리즈에 대해 동영상 인코더와 같은 멀티미디어 스트림 처리 응용을 최적으로 구현하기 위해서 필요한 캐쉬 성능 분석, 내부 메모리 구성 및 배치에 따른 성능 분석과 개선 방안에 대해 연구하였다. 분석 및 실험 결과, L2 메모리의 경우, 이중 집합연관 캐쉬로 구성하고, 남은 메모리는 내부 메모리로 구성하는 것이 수행 시간 성능 개선에 효과적임을 확인하였다. 또한, L1P 캐쉬의 경우는 자주 호출되고 시간이 많이 소요되는 루틴들을 연속적으로 내부 메모리에 배치하는 것이 L1P 캐쉬의 히트 율을 개선하며, L1D 캐쉬의 경우는 사용하는 데이터의 크기를 조절하므로 써 쉽게 히트 율을 개선할 수 있다는 것을 밝혔다. 본 논문의 연구 결과는 고성능 DSP 에 멀티미디어 스트림 처리 응용을 최적화로 구현하는데 도움을 줄 것으로 기대한다.

• 동의생리병리학회지
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• 제22권6호
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• pp.1487-1494
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• 2008

This study was conducted to determine the effect of Gagamjeongji-hwan (JJH)(Jiajiandingzhi-wan) and Evoidae Fructus (EF) on learning and memory disturbance and neuronal damage induced by focal ischemia in the rat. Rats were used for testing in the following three. Morris Water Maze, Cholineacetyltransferase (ChAT) immunohistochemistry, acetylcholine esterase (AchE) histochemistry. JJH+ISCH group (ischemia-induced rats pretreated with JJH) and EF+ISCH group (ischemia-induced rats pretreated with EF) significantly reduced the latency of swimming time, compared with those of ISCH group (ischemia-induced rats) in morris water maze acquisition test. JJH+ISCH group attenuated ischemia.induced learning and memory damage in morris water maze retention test. The density of ChAT neurons of the JJH+ISCH and EF+ISCH group in the hippocampal CA1 area was increased, compared to that of SAL+ISCH group (ischemia-induced rats pretreated with SAL). The density of AchE neurons of the JJH+ISCH and EF+ISCH group in the hippocampal CA1 and CA3 area was increased, compared to that of SAL+ISCH group. These results suggest that Gagamjeongji-hwan (JJH) and Evodiae Fructus (EF) may have significant protective effects on ischemia-induced brain damage and memory impairments.

• 대한한의학회지
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• 제28권2호통권70호
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• pp.1-12
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• 2007

Objective : Gagamchongmyung-tang is clinically one of the most popular prescriptions as an herbal medicine for the treatment of amnesia. In order to evaluate its neuroprotective effects on the ischemia-induced cognitive deficits caused by middle cerebral artery occlusion (MCAO), we examined its ability to reduce impairments of learning and memory of rats in the Morris water maze. Method and Result : Focal cerebral ischemia produced a decrease in acetylcholine transmission in the hippocampus, and deficits of learning and memory in the Morris water maze task. Treatment with two types of Gagamchongmyung-tang, methanol and water extracts, produced a substantial increase in acquisition in the Morris water maze. Treatment with methanol extract of Gagamchongmyung-tang increased the performance of the retention test in the Morris water maze. Consistent with behavioral data, immunohistochemical data showed that treatment with methanol extract, but not water extract, of Gagamchongmyung-tang significantly recovered reduction of AchE and ChAT reactivity in the hippocampal CAl area. Conclusion : These results demonstrated that methanol extract of Gagamchongmyung-tang has protective effects against ischemia-induced learning and memory impairments, and provided evidence of methanol extract of Gagamchongmyung-tang as a putative treatment for amnesia, vascular dementia, and longer memory.

• 대한한방내과학회지
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• 제27권1호
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• pp.253-264
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• 2006

Object: This research investigated effects of Jujadokseo-hwan on mice with Alzheimer's Disease induced by $amyloid-{\beta}$. According to Dongyibogam, Jujadokseo-hwan can cure amnesia. Amyloid-B is believed to induce oxidative stress and inflammation in the brain, postulated to play important roles in the pathogenesis of Alzheimer's disease. In this way $Amyloid-{\beta}$ induces Alzheimer's Disease. Methods : In order to make an efficient prescription and cope with dementia, learning and memory functions of mice were tested on passive avoidance test and V-maze task. $NF-{\kappa}B$ were measured from protein derived from the brain. RT-PCR was done for !gene analysis. Primers were protein kinase Band $NGF-{\alpha}$. Results : 1. Jujadokseo-hwan was effective for memory capacity on passive avoidance test. but noneffective for spatial memory capacity and locomotor activity on Y -maze task. 2. The measurement of $NF-{\kappa}B$ showed upward tendancies and the result of RT-PCR showed up-regulation when given Jujadokseo-hwan by mouth. Conclusion: Results suggest that Jujadokseo-hwan is effective on mice with Alzheimer's Disease induced by $amyloid-{\beta}$.

• 대한한방내과학회지
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• 제41권2호
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• pp.159-165
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• 2020

Introduction: We report a rare case in which the symptoms of hypersomnia were caused by cerebral infarction that occurred in the hypothalamus and hypothalamus. Case Presentation: The patient underwent Korean medicine treatments using Gami-seonghyangjeonggi-san, acupuncture, electroacupuncture, and physical therapy for 37 days. We evaluated the degree of improvement in hypersomnolence based on the amount of sleeping time and the degree of memory impairment with the patient's suggestive conditions as observed by the patient's guardian, and one-sided facial palsy using the Yanagihara Scale. As treatment was applied, sleeping time was decreased from 22 to 9 hours a day. Memory impairment did not show clear improvements as the patient could not recognize others when they visited during the period in which the patient underwent treatment. One-sided facial palsy showed no improvements and there were no changes in the Yanagihara Scale results. Conclusion: This case showed that Korean medicine treatment could be effective to relieve some of the symptoms of thalamus and hypothalamus infarction. Further research is needed to confirm the effectiveness of Korean medicine treatment.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2003년도 하계종합학술대회 논문집 Ⅲ
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• pp.1335-1338
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• 2003

Fixed-size memory allocation is one of the most promising way to avoid external fragmentation in dynamic memory allocation problem. This paper presents an experimental result of applying the fixed- size memory allocation strategy to Java virtual machine for embedded system. The result says that although this strategy induces another memory utilization problem caused by internal fragmentation, the effect is not very considerable and this strategy is well-suited for embedded Java system. The experiment has been performed in a real embedded Java system called the simpleRTJ.

• Tuberculosis and Respiratory Diseases
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• 제62권6호
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• pp.549-553
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• 2007

유육종증은 다발성 비건락성 육아종 형성을 특징으로 하는 원인 미상의 전신 질환으로 주로 폐, 피부, 림프절 등의 장기를 침범하며, 신경계 침범은 상대적으로 드문 것으로 알려져 있다. 저자들은 다른 신경학적 증상 없이 단기 기억장애만을 특징으로 하는 신경유육종증이 병발한 폐유육종증 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

• Smart Structures and Systems
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• 제8권1호
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• pp.69-92
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• 2011

This paper presents an emergent pattern recognition approach based on the immune network theory and hierarchical clustering algorithms. The immune network allows its components to change and learn patterns by changing the strength of connections between individual components. The presented immune-network-based approach achieves emergent pattern recognition by dynamically generating an internal image for the input data patterns. The members (feature vectors for each data pattern) of the internal image are produced by an immune network model to form a network of antibody memory cells. To classify antibody memory cells to different data patterns, hierarchical clustering algorithms are used to create an antibody memory cell clustering. In addition, evaluation graphs and L method are used to determine the best number of clusters for the antibody memory cell clustering. The presented immune-network-based emergent pattern recognition (INEPR) algorithm can automatically generate an internal image mapping to the input data patterns without the need of specifying the number of patterns in advance. The INEPR algorithm has been tested using a benchmark civil structure. The test results show that the INEPR algorithm is able to recognize new structural damage patterns.