• 제목/요약/키워드: interest-based P2P

검색결과 259건 처리시간 0.033초

Efficacy of cannabis-based medications compared to placebo for the treatment of chronic neuropathic pain: a systematic review with meta-analysis

  • Sainsbury, Bradley;Bloxham, Jared;Pour, Masoumeh Hassan;Padilla, Mariela;Enciso, Reyes
    • Journal of Dental Anesthesia and Pain Medicine
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    • 제21권6호
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    • pp.479-506
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    • 2021
  • Background: Chronic neuropathic pain (NP) presents therapeutic challenges. Interest in the use of cannabis-based medications has outpaced the knowledge of its efficacy and safety in treating NP. The objective of this review was to evaluate the effectiveness of cannabis-based medications in individuals with chronic NP. Methods: Randomized placebo-controlled trials using tetrahydrocannabinol (THC), cannabidiol (CBD), cannabidivarin (CBDV), or synthetic cannabinoids for NP treatment were included. The MEDLINE, Cochrane Library, EMBASE, and Web of Science databases were examined. The primary outcome was the NP intensity. The risk of bias analysis was based on the Cochrane handbook. Results: The search of databases up to 2/1/2021 yielded 379 records with 17 RCTs included (861 patients with NP). Meta-analysis showed that there was a significant reduction in pain intensity for THC/CBD by -6.624 units (P < .001), THC by -8.681 units (P < .001), and dronabinol by -6.0 units (P = .008) compared to placebo on a 0-100 scale. CBD, CBDV, and CT-3 showed no significant differences. Patients taking THC/CBD were 1.756 times more likely to achieve a 30% reduction in pain (P = .008) and 1.422 times more likely to achieve a 50% reduction (P = .37) than placebo. Patients receiving THC had a 21% higher improvement in pain intensity (P = .005) and were 1.855 times more likely to achieve a 30% reduction in pain than placebo (P < .001). Conclusion: Although THC and THC/CBD interventions provided a significant improvement in pain intensity and were more likely to provide a 30% reduction in pain, the evidence was of moderate-to-low quality. Further research is needed for CBD, dronabinol, CT-3, and CBDV.

CT를 이용한 혈복강의 등급: 비장 손상의 정도 및 회복의 객관화 (CT Based Hemoperitoneum Scoring for Clinicians: Objectifying the Severity of Splenic Injury and Recovery)

  • 신홍경;송라영;한호성;윤유석;조재영;황대욱;정규환;김영기;이우형
    • Journal of Trauma and Injury
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    • 제26권4호
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    • pp.273-279
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    • 2013
  • Purpose: In patients with splenic trauma, Computed Tomography (CT) scan is helpful in selecting treatment options and evaluating resolution after NOM (Non-Operative Management). The purpose of this study was to suggest a CT based hemoperitoneum (HP) scoring system that can easily be used by clinicians to evaluate the severity of injury and recovery. Methods: A retrospective review of patients with splenic trauma admitted to our hospital between May 2003 and January 2013 was conducted. Patients diagnosed with isolated spleen injury who had a CT scan on admission were included. 1 or 2 points were given according to location and amount of hematoma in the CT image. Using the existing ultrasonography (US) based HP scoring system, the same method was applied to obtain our CT based HP scoring (CBHS) system, which ranges from 0 to 8 points. The CBHS system can be easily used by clinicians for a quick assessment of splenic injury. Results: Of the 39 patients meeting the inclusion criteria, 6 patients were managed operatively and 33 nonoperatively. There was a significant difference in CBHS between the OM (operative management) group and the NOM group.(p=0.03) CBHS showed correlation with Hb (hemoglobin), Hct (hematocrit), spleen injury grade(AAST), and Hounsfield unit of ROI (Region of interest). (p=0.17, p=0.18, p<0.000, p=0.02, respectively) After successful NOM with stabilized Hb level, the amount of hemoperitoneum was scored in the follow-up CT. CBHS demonstrated correlation with decreased spleen injury grade, decreased Hounsfield unit of ROI (Region of interest) (p=0.039, p=0.049, respectively), and also objectively reflected patient recovery. Conclusion: CBHS can be used as an objective and intuitive tool for clinicians in grading the severity of splenic injury by scoring the amount of hemoperitoneum, and in assessing recovery.

고무풍선 중 니트로스아민류의 효과적 위해성 소통 전략에 관한 연구 (Effective Risk Communication Strategies for N-Nitrosamines in Rubber Balloons)

  • 김현경;이기영
    • 한국환경보건학회지
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    • 제49권4호
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    • pp.228-235
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    • 2023
  • Background: As the public interest in chemical substances found in daily life has increased, environmental health education content has been developed and related studies have been conducted. However, there is still insufficient research on methodologies for environmental health education. Objectives: This study aimed to explore risk communication strategies by focusing on N-nitrosamines in rubber balloons. Methods: In this study, two different health messages were composed: a gain-framed message emphasizing the advantages of practicing the health behavior and a loss-framed message emphasizing the negative consequences of not practicing the health behavior. The effect of the message containing risk information was evaluated by measuring the health beliefs and health behavior potential for female caregivers. As the Environmental Health Act defines a child as "a person under the age of 13," a total of 131 women with children under the age of 13 were studied. Results: The age, awareness, and interest of the participants in the gain frame group and these in the loss frame group were similar. In terms of message framing effect, the gain-framed message was more effective in terms of health belief and potential health behavior than was the loss-framed message. As a result of an independent t-test, among the six variables of health belief model the message effect was statistically significant at the level of p<0.05 in three variables: perceived severity (t=2.287, df=129, p=0.024), self-efficacy (t=2.123, df=129, p=0.036), and health behavior potential (t=2.094, df=129, p=0.038). Conclusions: This study presented a direction for effective environmental health education by studying the effects of risk communication messages based on scientific evidence. It is necessary to extend the scope of environmental health education research by expanding research into various household products.

학령전기 아동의 사고위험 지각 정도 (The Degree of Injury Risk Perception in Preschool Children)

  • 김신정;강경아;김성희;이정은
    • Child Health Nursing Research
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    • 제18권2호
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    • pp.68-75
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    • 2012
  • Purpose: The purpose of this study was to measure (the degree of) injury risk perception in preschool children. Methods: The data were collected from child day care centers and kindergartens located in Seoul, and Gyeonggi and Kwangwon Province. A questionnaire consisted of 28 pictures was administered to 186 preschool children. Results: The mean score for the injury risk perception was 21.83 (${\pm}3.89$), and 77.98 converted into a 100-point scale. According to sub-categories, 'burn prevention' ($.96{\pm}.13$) was the highest, 'interpersonal safety' ($.44{\pm}.31$) was the lowest. There were significant differences in injury risk perception according to gender (t=-2.358, $p$=.019), age (t=-2.101, p=.037), experience of safety education (t=-3.719, $p$ <.001), area of residence (t=-3.445, $p$=.001), injury experience (t=3.212, $p$=.002), and mother's occupation (t=-4.858, $p$ <.001). The highest item in the percentage of correct answer item was 'making jump on the desk', the lowest item in the percentage of correct answer item was 'not wearing safety equipment when rollerblading'. Conclusion: Based on this study, studies should be continued to standardize the instrument. In addition, it is recommended that an injury prevention education program should be developed based on the results of this study to stimulate demand and interest.

초등학생의 또래 칭찬활동 프로그램이 자아존중감 및 대인관계에 미치는 효과 (A Study on the effect of Friend-praise activity program of Elementary students for Self-esteem and Personal Relationship)

  • 오은주
    • 초등상담연구
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    • 제5권1호
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    • pp.159-184
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    • 2006
  • Lately, the rapid social and family system change, the entrance examination-centered circumstance in education have a negative influence not only on making up the affirmative self-esteem but also on building up the personal relationship through mutual communication with friends of the same age. Making children adapt well to school life and develop a good relationship in the class is an important subject in educational field. Thus, various school activities should offer lots of opportunities to increase their affirmative self-esteem and more specified performance-centered programs are required toform a harmonious relationship among parties of students. The purpose of this study is to improve an affirmative self-esteern and a desirable personal relationship of children through developing friend-praise program and adapting it to children. Based on the above purpose, the following subjects for this study 'are suggested. Firstly, is the friend-praise program effective in forming an affirmative self-esteem of elementary students? Secondly, is the friend-praise program successful in improving a desirable personal relationship in an elementary school? In addition, two hypotheses of study are decided on the basis of theoretical background and the former study. Hypothesis 1. The friend-praise program will have a meaningful effect on improving an affirmative self-esteem. Hypothesis 2. The friend-praise program will have a meaningful effect on improving a desirable personal relationship. In order to improve the above hypotheses, the experiment was carried out with two classes on the fourth grade in M elementary school in Wonju with being divided into one experimental group and the other comparative group. The friend-praise program which was adapted to the experimental group was composed with four steps as 'introduction', 'preparation', 'operation' and 'closing'. This program which has twelve categories was executed once or twice in a week and each class was continued for forty or sixty minutes. Contrastively, comparative group had no application of the main program. For the purpose of proving the hypotheses after adapting the program to students, I have executed both self-esteem test and personal relationship test. The tests were performed with using SPSS/Windows V10.0 and the statistic was conducted through independant sample t-test for the difference between groups and contrastive sample t-test for the individual difference in each group. The results of this study can be summarized like the followings: Firstly, from the result of previous and after tests, there was no meaningful change in the comparative group, but the experimental group showed meaningful difference in all categories of self-esteem(t=-4.496, p=.000). Especially, the general self-esteem(t=-3.216, p=.003), social self-esteem(t=-2.680, p=.012), homely self-esteem(t=-3.732, p=.001), and school self-esteem(t=-3.902, p=.000) showed a meaningful difference. At the same time, the experimental group also showed meaningful difference with the comparative group in self-esteem(t=-4.758, p=.000). Especially, the general self-esteem(t=2.581, p=.017), social self-esteem(t=3.160, p=.003), homely self-esteem(t=4.283, p=.000), and school self-esteem(t=4.110, p=.000) showed a meaningful difference. As a result of this experiment, the friend-praise program will have a meaningful effect on improving an affirmative self-esteem was proved. Secondly, there was no meaningful change in the comparative group, but the experimental group showed meaningful difference in all categories of personal relationship(t=-4.131, p=.000). Specifically, satisfaction(t=-2.113, p=.045), communication(t=-3.381, p=.002), confidence(t=-3.517, p=.001), intimacy(t=-3.958, p=.000), sensibility(t=-2.955, p=.006), openness(t=-4.318, p=.000) and interest(t=-2.941, p=.000) showed a meaningful difference. In the same instant, the experimental group also showed meaningful difference with the comparative group in all categories of personal relationship(t=3.897, p=.000). Especially, satisfaction(t=2.257, p=.003), communication(t=3.527, p=.001), confidence(t=3.704, p=.001), intimacy(t=3.904, p=.000), sensibility (t=4.382, p=.000), openness(t=2.648, p=.013) and interest(t=2.944, p=.006) showed a meaningful difference. Accordingly, the friend-praise program will have a meaningful effect on improving a desirable personal relationship was proved. Judging from all these results, we should provide primary students with various opportunities to take part in active programs which help them to set up their righteous sense of value, to solve their own problems and to develop their potentials. Consequently, many kinds of practice-centered program like the friend-praise program should be developed more systematically and teachers should apply all those programs to students according to their individual level and developmental stage.

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Kinematic analysis of POSTECH Hand I with new symbolic notation

  • Choi, H.-R.;Chung, W.-K.;Youm, Y.
    • 제어로봇시스템학회:학술대회논문집
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    • 제어로봇시스템학회 1991년도 한국자동제어학술회의논문집(국제학술편); KOEX, Seoul; 22-24 Oct. 1991
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    • pp.1764-1769
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    • 1991
  • Recently, dexterous mechanical hands have become of interest in the field of robotics. In this paper, a new symbolic C-Y notation is proposed for the kinematic modeling, and we solve the kinematics of a simplified model of POSTECH Hand 1, which is a 5 fingered, 20 degrees of freedom anthropomorphic hand. POSTECH Hand I is designed to have distinctive kinematic structure and the kinematic analysis of the hand is carried out using C-Y notation. To prove the feasibility of C-Y notation, D-H notation is also applied to the POSTECH Hand 1. In the inverse kinematic analysis, we neglect the fingertip geometry and assume the point contact with 3 degrees of freedom constraints. The configurations which optimize manipulability index[2] was obtained based on the simulation experiments on the SUN-4 graphic workstation using SUNPhigs graphic software.

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초등학교 4학년 『별자리를 찾아서』 단원 지도를 위한 놀이 과학 교실 활동 프로그램의 개발과 적용 (Development and Application of Play-Based Science Class Program for the Unit of 'Favorite Constellation' of 4th Grade Students)

  • 신영아;손정주;서은경
    • 과학교육연구지
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    • 제33권2호
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    • pp.248-257
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    • 2009
  • 본 연구는 초등학교 4학년 "별자리를 찾아서" 단원지도를 위한 놀이 과학 교실 활동 프로그램을 개발하여 실제 수업에 적용해 봄으로써 놀이 활동 적용수업이 초등학생의 학업성취도와 흥미도에 미치는 효과를 알아보기 위하여 시행되었다. 초등학교 4학년 1학기 중간고사 결과를 분석하여 평균이 유사한 4개 반을 선정하고 2개 반으로 구성된 비교집단에는 기존의 방법대로 교사용지도서를 분석하여 교사용지도서와 같은 방식과 흐름으로 수업을 진행하였고 나머지 2개 반의 실험집단에는 단원의 5차시의 수업 중 활동 일부를 놀이 과학 교실 활동 수업을 적용하여 시행하였다. 놀이 과학 교실 프로그램은 연구 단원의 학습목표 및 내용과 탐구요소를 분석하여 개발 하였고, 놀이 과학 교실 활동이 학업성취도에 미치는 효과를 알아보기 위해 학업성취도 검사문항을 선정, 개발하였다. 각각은 과학 교육 전문가 2인과 현직 교사 5인에 의해 수 회의 피드백 검토 과정을 거쳐 완성되어 각 집단에 2주간에 걸쳐 5차시 수업이 실시되었다. 사후 검사결과에서 두 집단은 독립표본 t-test 방법에 의해 유의수준 p=0.003으로 유의미하게 차별화 되었고, 실험 집단은 비교 집단에 비해 좋은 학업 성취도를 보였다. 설문 조사를 통한 실험집단의 흥미도 측정에서도 높은 흥미도 비율을 보였다. 결과적으로, '별자리 찾아서' 단원을 위한 놀이 과학 교실 활동 프로그램을 개발하여 초등학교 4학년 교실에 투입해 본 결과 학업성취도와 흥미도에서 뚜렷하게 긍정적 영향을 볼 수 있었다.

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인($^{31}$P) 자기공명분광법을 사용하여 사립체 근질병환자와 정상인과의 대사물질 비교조사 (Metabolic Abnormalities in Patients with Mitochondrial Myopathy Evaluated by In Vivo $^{31}$P Magnetic Resonance Spectroscopy)

  • Bo-Young Choe
    • Investigative Magnetic Resonance Imaging
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    • 제2권1호
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    • pp.89-95
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    • 1998
  • 목적 : 인($^{31}P$) 자기공명분광법을 사용하여 사립체 근병(mitochondria myopathy) 환자의 대퇴부 근조직의 대사물질의 변화를 정상인과 비교조사하였다. 대상 및 방법 : 사립체 근병환자 10명과 정상인 10명을 대상으로 1.5T MRI/MRS 장비를 사용하여 인($^{31}P$) 자기공명분광법을 적용하였다. 오른쪽 대퇴부위의 근조직에 $4{\;}{\times}{\;}4{\;}{\times}4{\;}cm^{3}$ 의 관심부위 (volume of interest ; VOI)를 선정하여 image selected in vivo spectroscopy (ISIS)를 저용하였다. 인대사불질의 정\ulcorner분석은 Marquart algorithm을 사용하였다. 결과 : 사립체 근병환자의 특징은 정상인과 비교하여 Pe/PCr 대사비율이 상당히 증가하고 (P=0.003), ATP/PCr 대사비율은 상당히 감소하였다(p=0.004). 특히 ATP 중 ${\beta}-ATP/PCr$ 비율의 변화가 가장 심하게 나타났다. 환자군과 정상군의 pH 차이는 통계학적으로 큰 의의는 없었다. 결론 : 인($^{31}P$) 자기 공명분광법은 사립체 근병환자의 대퇴부 근조직의 ATP/PCr 과 Pi/PCr 대사비율을 토대로 유용한 임상 평가 자료를 제공하고, 따라서 근대사물질의 질병을 이해하는데 도움을 줄 것으로 사료된다.

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간호대학생의 자아존중감과 생활스트레스가 건강증진행위에 미치는 영향 (The Effects of Self-Esteem and Life Stress on Health Promotion Behavior in Nursing Students)

  • 김수올
    • 한국응용과학기술학회지
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    • 제39권3호
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    • pp.423-432
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    • 2022
  • 본 연구의 목적은 간호대학생의 자아존중감, 생활스트레스와 건강증진행위의 관계를 확인하고, 건강증진행위에 미치는 영향을 파악하기 위한 서술적 연구이다. 연구 대상자는 A시 소재 간호대학생 115명으로 자료수집은 2022년 5월 2일부터 5월 27일까지 진행되었다. 수집된 자료는 기술통계, t-test, ANOVA 및 Scheffe' test로 분석하였다. 연구 결과, 건강증진행위는 자아존중감과 양의 상관관계(r=.59, p<.001)가 있었으며, 생활스트레스와는 음의 상관관계(r=-.45, p<.001)가 있는 것으로 나타났다. 간호대학생의 건강증진행위에 영향을 미치는 요인은 건강상태(β=.507, p<.001), 생활스트레스(β=.249, p=.002), 흡연(β=.156, p=.028) 순으로 나타났으며, 57.0%를 설명하였다. 본 연구 결과를 토대로 간호대학생의 건강증진행위를 증진시키기 위해 건강상태에 관심을 가지고 생활스트레스를 조절할 수 있는 건강증진 프로그램을 개발하여 시행하는 것이 필요하다.

유아교육 관련 학과 학생의 구강보건교육 필요도에 관한 연구 (Necessity of oral health education for students major in early childhood education)

  • 구효진;이명주
    • 대한치위생과학회지
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    • 제1권1호
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    • pp.11-21
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    • 2018
  • This research is intended to develop oral health education program that can improve quality of oral health of infants by investigating the actual condition of oral health education provided to students major in early childhood education and contents and method of oral health education that they needed. A questionnaire survey was conducted for 427 students enrolled in related departments such as the Early Childhood Education Division and the Early Childhood Education Department at five universities in Gyeongsangnam-do. Questionnaires consisted of general characteristics, awareness of oral health, presence of experience in oral health education, necessity of oral health education, preference for oral health education method, oral health education contents. The collected data were analyzed by SPSS(Statistical Package for the Social Science) Ver 20.0. 1. Presence of experience in oral health education based on the general characteristics showed statistically significant differences only concerning the 'school system' and the 'school year' (p<0.05), and subjective awareness of oral health based on the presence of oral health education experiences showed statistically significant differences concerning the 'interest in oral health' and the 'importance of oral health' (p<0.05). 2. Necessity of oral health education based on the subjective awareness of oral health showed statistically significant differences concerning the 'interest in oral health' and the 'importance of oral health' (p<0.05). 3. Necessity of oral health education based on the preference for oral health education method showed statistically significant differences concerning the 'intention to participate in oral health education' and the 'oral health education cycle' (p<0.05). 4. The most necessary information for oral health education is proper toothbrushing method 4.24, cause of tooth decay and prevention method 4.13, helpful food and poor food for tooth 3.97, toothbrush selection and storage method 3.85. Fluoride application and fissure sealant were lowest 3.38. As a result of this research, necessity of oral health education was large regardless of general characteristics, experience in oral health education, subjective awareness of oral health, and preference for oral health education. Also the more the 'interest in oral health' in 'subjective awareness of oral health', the more the 'necessity of oral health education' and 'intention to participate in oral health education'. Therefore it is necessary to develop systematic and repetitive oral health education for students major in early childhood education.