• Radiation Oncology Journal
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• v.27 no.1
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• pp.1-9
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• 2009

There has been recent interest in radiation-induced bone injury in clinical conditions, especially for pelvic insufficiency fracture (PIF). A PIF is caused by the effect of normal or physiological stress on bone with demineralization and decreased elastic resistance. Pelvic radiotherapy (RT) can also contribute to the development of a PIF. A PIF has been regarded as a rare complication with the use of megavoltage equipment. However, recent studies have reported the incidence of PIFs as $8.2{\sim}20%$ after pelvic RT in gynecological patients, an incidence that was higher than previously believed. The importance of understanding a PIF lies in the potential for misdiagnosis as a bony metastasis. If patients complain of pelvic pain after whole-pelvis radiation therapy, the presence of a PIF must be considered in the differential diagnosis. The use of multibeam arrangements and conformal RT to reduce the volume and dose of irradiated pelvic bone can be helpful to minimize the risk of fracture. In addition to a PIF, osteonecrosis and avascular necrosis of the femoral head can develop after radiation therapy. Osteoradionecrosis of the pelvic bone is a clinical diagnostic challenge that must be differentiated from an osseous metastasis. A post-radiation bone sarcoma can result as a long-term sequela of pelvic irradiation for uterine cervical cancer.

• 제어로봇시스템학회:학술대회논문집
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• 2005.06a
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• pp.700-705
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• 2005

The purpose of this project is the derivation and development of techniques for the new estimation of robustness for the systems having uncertainties. The basic ideas to analyze the system which is the originally nonlinear is Lyapunov direct theorems. The nonlinear systems have various forms of terms inside the system equations and this investigation is confined in the form of bounded uncertainties. Bounded means the uncertainties are with same positive/negative range. The number of uncertainties will be the degree of freedoms in the calculation of the stability region. This is so called the robustness bounds. This proposition adopts the theoretical analysis of the Lyapunov direct methods, that is, the sign properties of the Lyapunov function derivative integrated along finite intervals of time, in place of the original method of the sign properties of the time derivative of the Lyapunov function itself. This is the new sufficient criteria to relax the stability condition and is used to generate techniques for the robust design of control systems with structured perturbations. Using this relaxing stability conditions, the selection of Lyapunov candidate function is of various forms. In this paper, the quadratic form is selected. this generated techniques has been demonstrated by recent research interest in the area of robust control design and confirms that estimation of robustness bounds will be improved upon those obtained by results of the original Lyapunov method. In this paper, the symbolic algebraic procedures are utilized and the calculating errors are reduced in the numerical procedures. The application of numerical procedures can prove the improvements in estimations of robustness for one-and more structured perturbations. The applicable systems is assumed to be linear with time-varying with nonlinear bounded perturbations. This new techniques will be extended to other nonlinear systems with various forms of uncertainties, especially in the nonlinear case of the unstructured perturbations and also with various control method.

• Journal of Korean Academy of Nursing
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• v.36 no.5
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• pp.782-791
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• 2006

Purpose: The purpose of this study was to conceptualize and clarify a concept of "preparatory grief" in terminal cancer patients. Method: A hybrid model of concept development was applied to develop a concept of preparatory grief, which included a field study carried out in Busan, Korea. Participants of this study were 8 cancer patients. Results: On the basis of our literature, research and clinical experience, the concept of preparatory grief emerged as a complex phenomenon playing an important role in five areas; physical, emotional, interpersonal, religious, and transcendental dimensions. Two new attributes were defined through a field phase; trust of the post-mortal world and a serene state of mind. Indicators reflected attitudes of sadness, worry, regret, capability to adapt and hope. The results of preparatory grief were loss of energy and interest, emotional chaos, contemplation, taciturnity and restoration. Conclusions : Differentiating among preparatory grief and other symptoms in cancer patients is essential because of therapeutic implications. Understanding preparatory grief is necessary in order to manage cancer patients for promoting quality of life so that its application may have a positive impact on the patient's life.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.8
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• pp.3711-3719
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• 2016

Drawbacks of conventional cancer treatments, with lack of specificity and cytotoxicity using current approaches, underlies the necessity for development of a novel approach, gene-directed cancer therapy. This has provided novel technological opportunities in vitro and in vivo. This review focuses on a member of an apoptosis inhibitor family, survivin, as a valuable target. Not only the gene but also its promoter are applicable in this context. This article is based on a literature survey, with especial attention to RNA interference as well as tumor-specific promoter action. The search engine and databases utilized were Science direct, PubMed, MEDLINE and Google. In addition to cell-cycle modulation, apoptosis inhibition, interaction in cell-signaling pathways, cancer-selective expression, survivin also may be considered as specific target through its promoter as a novel treatment for cancer. Our purpose in writing this article was to create awareness in researchers, emphasizing relation of survivin gene expression to potential cancer treatment. The principal result and major conclusion of this manuscript are that survivin structure, biological functions and applications of RNA interference systems as well as tumor-specific promoter activity are of major interest for cancer gene therapy.

• The Journal of Society for e-Business Studies
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• v.14 no.2
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• pp.23-39
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• 2009

Increasing number of business and technology expansion has sparked a growing interest in IT service business evaluation. However, it is not an easy task to come up with a fair and objective evaluation of IT service business due to the difficulties involved in the definition performance assets (marketing, human resources etc.) and knowledge assets with respect to its industry. Several public organizations in Korea are developing a "standardized evaluation protocol" based on qualitative method. But the standard evaluation protocol does not provide suitable guidelines on how to construct and evaluate the key index of IT service business. The main objective of this study is in the development of a systematic approach for the evaluation of IT service business competitiveness by emphasizing the qualitative and quantitative index to be evaluated in the framework. Application of the developed framework and guideline format showed that the used of the framework in this study provided relatively more efficient evaluation results in IT service industry.

• Journal of the Korea Society of Computer and Information
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• v.19 no.4
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• pp.63-69
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• 2014

Third Person Action Game is a genre receiving continuous interest from many game enthusiasts. The most distinctive feature about third person action games is that the user can actually see the character as well as the various actions, which in turn increases user engagement. Many games are developed using game engines. However, this study designs a third person action game using only DirectX library instead of the specialized techniques in game engines. By doing so, the game development costs will be minimalized. The study also uses several basic algorithms in order to process the various events and to make the animation effects more efficiently managed in the graphic device. The performance superiority is demonstrated by the results of the study.

• Journal of Digital Convergence
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• v.12 no.6
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• pp.341-347
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• 2014

Among methods of the big data process, big data process under the cloud environment is becoming a main topic. As part of solving faced problem and strengthening industrial competitiveness in the medical and health industry, discussion on ways to activate big data is actively being conducted. Because the reason is a paradigm shift, saving pressure for increasing health care costs, and increased consumer interest for the level of service. In this paper, we find out the relationship between the cloud and big data. And we are to research and analysis a cloud-based big data case in the medical field. Finally we propose the efficient utilization and future outlook. For the smooth functioning of cloud-based medical big data, we have to solve the problems like infrastructure extension, analysis/application software development, and professional manpower training. In addition, we have to correct insufficient laws maintenance to the Cloud utilization, and improve the security and the recognition to personal information, and solve authority for data centralization.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.16 no.2
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• pp.23-35
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• 2017

Work zone traffic control is of keen interest because both traffic operations and safety performances are directly affected by traffic management methods. In particular, work zone traffic on two-lane roads needs to be managed in more efficient and safer manners due to its unique characteristics of alternative right-of-way assignment. This study developed a dynamic control algorithm that can be used for real-time operations of two-lane work zone traffic. The performance of the developed algorithm was evaluated by VISSIM microscopic traffic simulator. An applied programming interface (API) based program was developed to plug-in the control algorithm onto the simulator. The results demonstrated the feasibility of the proposed control algorithm for two-lane work zone.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.17 no.5
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• pp.151-159
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• 2018

Recently, stereoscopic technology has become a potential for blue ocean as a new growth power industry, and interest in it has been steadily increasing with the development of virtual and augmented reality technologies. Various methods such as binocular parallax and polarized glasses have been developed and used for stereoscopic image expression, but they have limitations such as eye damage, headache, crosstalk and resolution degradation. In this paper, we present a new method of stereoscopic image representation that can overcome the limitations and verify its applicability through basic experiments for object extraction and real - time image representation.

• Journal of Digital Contents Society
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• v.19 no.3
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• pp.425-433
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• 2018

Recently, the rate of openness of public data has increased and related development is also increasing. As recent government policies have also focused on opening public data, the Public Data Index among OECD member nations has been ranked first for two consecutive years. However, despite the government's interest and active support, the post-start-up survival rate was the lowest among the OECD countries. The lowest survival rate was found to be the biggest failure factor for consumers to exhibit unwanted products. In this study, we analyze the desired parts of the consumers that are lacking in the start-up and propose the service of location analysis. In this process, we utilize data related to entrepreneurship among various public data supported by the government.