• Communications for Statistical Applications and Methods
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• v.19 no.1
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• pp.33-45
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• 2012

The primary interest of drug development studies is to estimate the smallest dose that shows a significant difference from the zero-dose control. The smallest dose is called the Minimum Effective dose(MED). In this paper, we suggest a nonparametric procedure to simultaneously find the MED of each group based on placements. The Monte Carlo simulation is adapted to estimate the power and the family-wise error rate(FWE) of the new procedures with those of discussed nonparametric tests to find MED.

• The Korean Journal of Nuclear Medicine
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• v.39 no.4
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• pp.215-223
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• 2005

Current interest in the regioselective N-functionalization of tetraazacycloalkanes (cyclen and cyclam) stems mainly from their complexes with radioactive metals for applications in diagnostic ($^{64}Cu,\;^{111}In,\;^{67}Ga$) and therapeutic ($^{90}Y$) medicine, and with paramagnetic ions for magnetic resonance imaging ($Gd^{+3}$). Selective methods for the N-substitution of cyclen and cyclam is a crucial step in most syntheses of cyclen and cyclam-based radiometal complexes and bifunctional chelating agents. In addition, mixing different pendent groups to give hetero-substituted cyclen derivatives would be advantageous in many applications for fine-tuning the compound's physical properties. So far, numerous approaches for the regioselective N-substitution of tetraazacycloalkanes and more specifically cyclen and cyclam are reported. Unfortunately, none of them are general and every strategy has its own strong points and drawbacks. Herein, we categorize numerous regioselective N-alkylation methods into three strategies, such as 1) direct substitution of the macrocycle, 2) introductiou of the functional groups prior to cyclization, and 3) protection/iunclionallrationideproteclion. Our discussion is also split into the methods of mono- and tri-functionalization and di-functionalizataion based on number of substituents. At the end, we describe new trials for the new macrocycles which iorm more stable metal complexes with various radiometals, and briefly mention the commercially available tetraazacycloalkanes which are used for the biconjugation of biomolecules.

• Journal of the Korea Safety Management & Science
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• v.6 no.2
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• pp.211-229
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• 2004

The basis of cyber trading has been sufficiently developed with innovative advancement of Internet Technology and the tendency of stock market investment has changed from long-term investment, which estimates the value of enterprises, to short-term investment, which focuses on getting short-term stock trading margin. Hence, this research shows a Short-term Stock Price Forecasting System on Learning Agent System using DTA(Decision Tree Algorithm) ; it collects real-time information of interest and favorite issues using Agent Technology through the Internet, and forms a decision tree, and creates a Rule-Base Database. Through this procedure the Short-term Stock Price Forecasting System provides customers with the prediction of the fluctuation of stock prices for each issue in near future and a point of sales and purchases. A Human being has the limitation of analytic ability and so through taking a look into and analyzing the fluctuation of stock prices, the Agent enables man to trace out the external factors of fluctuation of stock market on real-time. Therefore, we can check out the ups and downs of several issues at the same time and figure out the relationship and interrelation among many issues using the Agent. The SPFA (Stock Price Forecasting System) has such basic four phases as Data Collection, Data Processing, Learning, and Forecasting and Feedback.

• Journal of the Korea Furniture Society
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• v.18 no.4
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• pp.296-306
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• 2007

As life style changes, the demand for stacking chairs are increasing as the use of event halls or outside furniture where people gather in crowd is increasing. Early stacking chairs were mainly made to pile up a great amount and store, but in modern days it also has a decorative purpose. Besides, the development of various new materials and applied technology of furniture manufacture, the structure and design of stacking chair is becoming more interesting. Basically, according to the structure of the leg, the form and method of piling up is decided. The structure of the leg means the location of the leg connected to the seat, and according to the location, it can be piled up as upper, front, or rotational type. Such is the way how stacking chairs are classified according to the location of the leg, with its basis; the structure of stacking chair is reviewed. Now, chair for piling up is overcoming its simple function, which aesthetic beauty or arrangement of color after piling up is being considered. Also, according to storing, moving, and the place of use, various designs are demanded. As people's interest in stacking chair is increasing, various research regarding design should continue.

• Current Industrial and Technological Trends in Aerospace
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• v.7 no.1
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• pp.56-67
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• 2009

From 1990s, the lunar exploration programs, suspended over 20 years after the project Apollo's first successful human landing on the Moon in 1969, have been restarted according to a revived interest in Moon. In recent, several nations progress their own lunar exploration program successfully. In this report, to investigate the technical trends of the onboard propulsion system for the lunar orbiter, technical features related to the performance of the propulsion system of the lunar orbiters developed since 1990 are surveyed. In the future, it is expected that this technical report can provide a fundamental guideline for selecting a proper type of the onboard propulsion system for the domestic lunar orbiter.

• Current Industrial and Technological Trends in Aerospace
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• v.7 no.2
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• pp.106-114
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• 2009

Until now, The Market of aviation parts had led by OEM(Original Equipment Manufacturer) parts because of aviation industry's nature required higher reliability and safety. But recently, The interest about PMA parts in aviation market is increasing continuously with various environmental changes, such as economic stagnation, oil price rise, development of the manufacture technique and newly rising market of Asia-Pacific region. Actually, after 2006, FAA PMA approval parts are increasing at a rate of around 40,000 parts per year and 2.5% of PMA parts penetration, in 2007, in Asia-Pacific market is forecast to enlarge up to 8% in 2017. So, this paper introduces the process requirements of FAA PMA / EASA EPA and the status of PMA market in order to enhance understanding for certification for aviation parts and to review a new PMA market.

• Journal of Korea Game Society
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• v.10 no.5
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• pp.75-85
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• 2010

In addition to the quantitative growth of the games industry as a game addiction and social problems have also been increased. Addiction adoption of the resolution was presented to the fatigue system. In this study, flow and addiction affects 6 factors(self-control, positive expectations, interest, competition, positive self-efficacy, negative self-efficacy), depending on whether the adoption lag Flow to affect in any empirical analysis. This fatigue system effect on the game development and to enhance users' flow to do what strategies for theoretical and practical implications are to provide.

• Journal of Korean Elementary Science Education
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• v.28 no.1
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• pp.1-8
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• 2009

This study was to analyze the effect of 'mobile science-lab' through the survey of students' perception. 'Mobile science-lab' is the one of the most distinguished public science programs and has been made in order to promote the students' understanding of science by providing students an opportunity to be engaged in several activities of science and high-technology. To fulfill the purpose of this study, we analyzed the opinions of 3,643 students who participated in 'mobile science-lab'. As the results, 'mobile science-lab' is very effective on improving the students' interest and concern of science. Most students recognized that the best advantage of 'mobile science-lab' is the participation in experiments. To overcome the mobile science-lab's some limits, more researches including development of the training program of science show coordinators should be done.

• Journal of Global Scholars of Marketing Science
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• v.8
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• pp.269-290
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• 2001

Customer relationship management is getting more and more important due to the recent development in Internet. Internet allows businesses to collect customers' information, to contact on individual base, and to communicate bilaterally. Much increased interest has many researchers make effort to verify effectiveness and efficiency of relationship marketing. Despite the importance of characteristics of relationship, there has been no systematic study of the uncoupling of internet shopping mall-customer. The purpose of this study is to develop a model that depicts the key variables of relationship in shopping mall-customer situation. The findings of Qualitative research indicate that on-line shopping mall customers do form a long-term orientation toward shopping malls as they do in off-line.

• Journal of Korean Public Health Nursing
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• v.28 no.1
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• pp.5-21
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• 2014

Purpose: The purpose of this study was to examine perceived needs for exercise programs among adults in the workforce based on sociodemographic characteristics and health-related behaviors. Methods: The sample consisted of 182 office workers, sales workers, and service workers recruited at a worksite in Seoul (97 males and 85 females, Mean age=34.6, SD=7.71). Study participants completed a structured questionnaire on health-related behaviors and areas of needs for exercise programs. Analysis of data was performed using descriptive statistics and chi-square tests. Results: Workers with greater interest in exercise reported to engage in exercise. Significant differences were observed in goals of exercise, preferred exercise, preferred methods for delivery of exercise, preferred exercise monitoring, and social support for exercise maintenance according to age, sex, marital status, education, commuting time, occupation, alcohol use, smoking, and current participation in exercise. There were no differences in areas of exercise program needs by consumption of high calorie foods. Conclusion: Public health nurses can use these findings for development and implementation of tailored exercise programs to promote health for workers whose physical activity is insufficient.