• BMB Reports
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• v.42 no.11
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• pp.697-704
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• 2009

Membrane proteins play important roles in the biology of the cell, including intercellular communication and molecular transport. Their well-established importance notwithstanding, the high-resolution structures of membrane proteins remain elusive due to difficulties in protein expression, purification and crystallization. Thus, accurate prediction of membrane protein topology can increase the understanding of membrane protein function. Here, we provide a brief review of the diverse computational methods for predicting membrane protein structure and function, including recent progress and essential bioinformatics tools. Our hope is that this review will be instructive to users studying membrane protein biology in their choice of appropriate bioinformatics methods.

• Korean System Dynamics Review
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• v.16 no.3
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• pp.49-75
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• 2015

A company is a core of free market capitalism. It needs to be sustainable to make capitalism better. In this reason, a company has to be ethical to be longer, because unethical company can not be survival. It means that we should understand what is the ethical company and how to be. Because interdisciplinary exchanges give a hint to understand what and how from, so it was studied to find the academic theories which have a relationship with ethics or morality not only in the area of Business management, but also Psychology, Pedagogy, Ethics, Philosophy, and etc.. Making a visible structure by System Dynamics with results through interdisciplinary exchanges to understand the reason why unethical accidences are rising and damages are growing although companies pay "Ethics Pays" more and more to reduce immoral cases is the goal of this study. On the theory of "Social Ethics", 5 ways explain the reason why unethical behavior has not been demolished make a complex structure, which was founded from studying interdisciplinary exchanges such as "Ethics Pays", "Moral Reasoning", "Social Cost", and "Fallacy of Compositions". Finding the controllers and Factors of this model to control to be better, then the market could be more effective with lesser social cost.

• 한국생물공학회:학술대회논문집
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• 2005.04a
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• pp.470-470
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• 2005

• Journal of Institute of Control, Robotics and Systems
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• v.19 no.9
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• pp.834-838
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• 2013

This paper proposes a new ball robot which has a four axis structure and four motors that directly actuate the ball to move or to maintain the balance of the robot. For the Balancing control, it is possible to use non-model-based controller to control simply without complex formula. All the gains of the controller are heuristically adjusted during the experiments. The tilt angle is measured by IMU sensors, which is used to generate the control input of the roll and pitch controller to make the tilt angle zero. The performance of the designed control system has been verified through the real experiments with the developed ball robot.

• Journal of the Korean Magnetics Society
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• v.5 no.5
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• pp.690-694
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• 1995

Reducing media noise is a key to realizing high areal recording density. However, perpendicularly oriented Co-Cr films, stong candidates for high density recording media, have received little attention in terms of recording noise. We studied the noise characteristics of Co-Cr based alloy films by varying the compositionally separated structure. Co-Cr films with fine compositionally separated microstructure were observed to have low noise, which recording density dependence were negative or week. Studies on control of the microstructure and magnetic properties in combination with noise analysis are important to realize high density recording media.

• The Journal of Korean Medicine
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• v.32 no.1
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• pp.56-66
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• 2011

Background: This was a study to analyze Sanghanron through network theory, as the first attempt to construct network models for systems biomedicine in traditional Korean medicine. For this purpose, we investigated the network structure with priority given to two-node connections between symptoms and herbs of Taeyangbyung compilation in Sanghanron. Purpose: We had three goals in carrying out this study. First, to establish the minimum clinical grouping data sets for symptoms and herbs of Taeyangbyung compilation in Sanghanron. Second, to make index files for the obtained data sets. Third, to generate a network structure for systems biomedicine in this part, and analyze its relationship. Methods: Using MS office Excel and Netminer software, we constructed the minimum clinical grouping data sets and the network for systems biomedicine about symptoms and herbs of Taeyangbyung compilation in Sanghanron, and analyzed its relationship. Results: We established the minimum clinical grouping data sets for symptoms and herbs of Taeyangbyung compilation in Sanghanron, using MS Excel. We constructed a network to structurize our database through two-node connections of Netminer program, and analyzed its relationships. Conclusions: Further research on network model for systems biomedicine between symptoms and herbs for three Yang and three Um(Taeyang, Soyang, Yangmyung, Taeum, Soum, Gualum) disease compilation is necessary.

• Animal cells and systems
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• v.9 no.3
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• pp.139-144
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• 2005

The attractant (orange light) or repellent (white light) signal is transmitted from SRI (Sensory Rhodopsin I) via protein-protein interaction with its transducer Htrl (Halobacterial Transducer for Sensory Rhodopsin I) which in turn controls a cytoplasmic phospho-transfer pathway that modulates flagella motor switching in Halobacterium salinarum. Some mutations in both SRI and Htrl showed an unusual mutant phenotype called inverted signaling, in which the cell produces a repellent response to normally attractant light. Twelve mutations at the Glutamate 56 (E56) position in the second transmembrane helix of Htrl were introduced by site-specific random mutagenesis. Almost all E56 mutants showed orange-light inverted responses in pH and temperature-dependent manners except E56D and E56Y. Except for these two mutants, all mutants accelerated the $S_{373}$ decay compared to wild-type at $18^{\circ}C$. This supported that there is an interaction between SRI and the second transmembrane of Htrl. Also a structural model of Htrl based on the Tar crystal structure and the secondary structure prediction program proposed the E56 residue to be in the middle of the proton channel. The most important observation is that the E56 mutant provides the evidence that this residue is very sensitive for signal relay, which can be explained by the open and closed conformations of the channel (A and R conformations) in SRI, as was postulated by the unified conformational shuttling model for transport and signaling.

• Journal of Powder Materials
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• v.22 no.4
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• pp.278-282
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• 2015

The GaN-powder scrap generated in the manufacturing process of LED contains significant amounts of gallium. This waste can be an important resource for gallium through recycling of scraps. In the present study, the influence of annealing temperatures on the structural properties of GaN powder was investigated when the waste was recycled through the mechanochemical oxidation process. The annealing temperature varied from $200^{\circ}C$ to $1100^{\circ}C$ and the changes in crystal structure and microstructure were studied. The annealed powder was characterized using various analytical tools such as TGA, XRD, SEM, and XRF. The results indicate that GaN structure was fully changed to $Ga_2O_3$ structure when annealed above $900^{\circ}C$ for 2 h. And, as the annealing temperature increased, crystallinity and particle size were enhanced. The increase in particle size of gallium oxide was possibly promoted by powder-sintering which merged particles to larger than 50 nm.

• New & Renewable Energy
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• v.7 no.1
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• pp.36-44
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• 2011

Technology is developed from the efficient interaction with other technology files while building up its own research field. This study analyzes the structure of solar cell research area and describes its paths of the technology development in terms of interdisciplinary diversity using the Co-Classification method during 1979-2009. As a results, 1,380 studies are determined as the interdisciplinary among the 2,605 studies. It shows that 52.98% of the solar cell researches have interdisciplinary relationships with two or more research fields. In addition, we show that the research area of solar cell technology is composed by Material Science, Multidisciplinary and Energy & Fuel, Physics, Applied, Chemistry, Physical from the Co-Classification matrix and network analysis. It means the complexity of the technological knowledge production increased with the concept of interdisciplinary. The results can be used for the planning of the efficient solar cell technology development.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.15 no.1
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• pp.87-94
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• 2011

Objectives: The purpose of our study was to verify whether the Seven Emotions evaluated by Guibi-Tang questionnaire (GTQ) were predictive of self-awareness level of one's quality of life (QOL). Methods: Eighty volunteers participated in this study and completed the GTQ. In addition, the volunteers were asked to answer one's self-awareness of the QOL using numerical scale. Factor analysis was conducted for extraction of GTQ factors. Structural Equation Model (SEM) was conducted to verify path structure. Results: The estimates of the four factors on the level of one's QOL demonstrated that Chest Factor (=-0.330) showed the highest level of correlation followed by the seven emotions (=-0.213); Deficient fire (=0.141); and Qi Deficiency (=-0.023). Model fit is $X^2$=34.740 (df=36), GFI=0.931, AGFI=0.873, NFI=0.867, RFI=0.797, IFI=0.975, TLI=1.006, CFI=1.009, RMSEA=0.000. Therefore, considering these values, SEM could be accepted as a workable model. Conclusions: Our study results suggest that According to SEM, The Seven Emotions evaluated by GTQ are predictable for self-awareness of one's QOL.