• International Journal of High-Rise Buildings
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• v.1 no.2
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• pp.107-116
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• 2012

The overarching objective of this study is to predict the convective heat transfer around a human body under forced strong airflow conditions assuming a strong wind blowing through high-rise buildings or an air shower system in an enclosed space. In this study, computational fluid dynamics (CFD) analyses of the flow field and temperature distributions around a human body were carried out to estimate the convective heat transfer coefficient for a whole human body assuming adult male geometry under forced convective airflow conditions between 15 m/s and 25 m/s. A total of 45 CFD analyses were analyzed with boundary conditions that included differences in the air velocity, wind direction and turbulence intensity. In the case of approach air velocity $U_{in}=25m/s$ and turbulent intensity TI = 10%, average convective heat transfer coefficient was estimated at approximately $100W/m^2/K$ for the whole body, and strong dependence on air velocity and turbulence intensity was confirmed. Finally, the formula for the mean convective heat transfer coefficient as a function of approaching average velocity and turbulence intensity was approximated by using the concept of equivalent steady wind speed ($U_{eq}$).

• Genomics & Informatics
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• v.3 no.3
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• pp.53-62
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• 2005

MicroRNAs play an important role in regulating gene expression, but their target identification is a difficult task due to their short length and imperfect complementarity. Burge and coworkers developed a program called TargetScan that allowed imperfect complementarity and established a procedure favoring targets with multiple binding sites conserved in multiple organisms. We improved their algorithm in two major aspects - (i) using well-defined UTR (untranslated region) database, (ii) examining the extent of conservation inside the 3' UTR specifically. Average length in our UTR database, based on the ECgene annotation, is more than twice longer than the Ensembl. Then, TargetScan was used to identify putative binding sites. The extent of conservation varies significantly inside the 3' UTR. We used the 'tight' tracks in the UCSC genome browser to select the conserved binding sites in multiple species. By combining the longer 3' UTR data, TargetScan, and tightly conserved blocks of genomic DNA, we identified 107 putative target genes with multiple binding sites conserved in multiple species, of which 85 putative targets are novel.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.67 no.9
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• pp.1224-1231
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• 2018

Automatic age estimation has been used in many social network applications, practical commercial applications, and human-computer interaction visual-surveillance biometrics. However, it has rarely been explored. In this paper, we propose an automatic age estimation system, which includes face detection and convolutional deep learning based on an inception module. The latter is a 22-layer-deep network that serves as the particular category of the inception design. To evaluate the proposed approach, we use 4,000 images of eight different age groups from the Adience age dataset. k-fold cross-validation (k = 5) is applied. A comparison of the performance of the proposed work and recent related methods is presented. The results show that the proposed method significantly outperforms existing methods in terms of the exact accuracy and off-by-one accuracy. The off-by-one accuracy is when the result is off by one adjacent age label to the above or below. For the exact accuracy, the age label of "60+" is classified with the highest accuracy of 76%.

• Proceedings of the Korean Society of Crop Science Conference
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• 2023.04a
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• pp.156-156
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• 2023

Salinity is a major abiotic stress that limits rice productivity in many regions of the world. In order to develop salt stress tolerant rice plants, genetic engineering is a promising approach. We characterized the molecular function of rice C3H2C3 as a really interesting new gene (RING). Oryza sativa RING finger protein H2-3 (OsRFPH2-3) was highly expressed in 100 mM NaCl. To identify the localization of OsRFPH2-3, we fused vectors that include C-terminal GFP protein (35S;;OsRFPH2-3-GFP). OsRFPH2-3 was expressed in the nucleus in rice protoplasts. An in vitro ubiquitin assay demonstrated that OsRFPH2-3 possessed E3-ubiquitin ligase activity. However, the mutated OsRFPH2-3 were not possessed any E3-ubiquitin ligase activity. Under salinity conditions, OsRFPH2-3-overexpressing plants exhibited higher chlorophyll, proline, SOD, POD, CAT, and soluble sugar contents and lower H₂O₂ accumulation than wild-type plants, supporting transgenic plants with enhanced salinity tolerance phenotypes. OsRFPH2-3-overexpressing plants exhibited low Na+ accumulation and Na+/K+ ratios in their roots. Theses results suggest that overexpression of OsRFPH2-3 can make plant insensitivity about salinity conditions.

• International journal of advanced smart convergence
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• v.12 no.4
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• pp.142-146
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• 2023

We present a method for generating 3D structures and rendering objects by combining VAE (Variational Autoencoder) and GAN (Generative Adversarial Network). This approach focuses on generating and rendering 3D models with improved quality using residual learning as the learning method for the encoder. We deep stack the encoder layers to accurately reflect the features of the image and apply residual blocks to solve the problems of deep layers to improve the encoder performance. This solves the problems of gradient vanishing and exploding, which are problems when constructing a deep neural network, and creates a 3D model of improved quality. To accurately extract image features, we construct deep layers of the encoder model and apply the residual function to learning to model with more detailed information. The generated model has more detailed voxels for more accurate representation, is rendered by adding materials and lighting, and is finally converted into a mesh model. 3D models have excellent visual quality and accuracy, making them useful in various fields such as virtual reality, game development, and metaverse.

• Journal of the Korean institute of surface engineering
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• v.12 no.3
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• pp.207-216
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• 1979

Environmental pollution or contaminations caused by various kinds of pollutants have become one of most serious problems of our time. Environ mental pollution is the unfavoralble alteration of our surroundings, through direct or indirect effects of changes in energy patterns, rediation levels, chemical and physical constitution and abundances of organisms. These changes may affect humans directly or through their supplies of water and of agicultural and other biological products, their physical objects or possessions, or their opportunities for recreation and appreciation of nature. Pollutants that meet the criteria of this definition of environmental pollution are numerous: gases (such as sulfur dioxide and nitrogen oxides) and paniculate matter (such as smoke particles, lead aerosols, and asbestos) in the atmosphere; pesticides and radioactive isotopes in the atmosphee and in waterways; sewage, organic. chemicals, and phosphates in water; solid wastes on land; excessive heating (thermal pollution) of rivers and lakes; and many others. Some of these pollutants are introduced into the environment naturally, others by human actions, and most in both ways. Our major concer is with environmental pollution resulting wholly or largely as a by-product of human activities, because these can be controlled most readily. Environmental pollution cannot be solved by science and technology alone. It should be handled by an interdisciplinary approach with combined methods of science and technology as wen as social science disciplines for the better solution of this critical problem. In this respect, introducing "Environmental Science," a new scientific approach for the solution of environmental problems, which is now widely accepted by most developed countries of the world will be very helpful for systematization of theoretical basis for a new scientific approach to environmental pollution. Environmental science is "the study of all systems of air, land, water, energy, and life that surround Man. It includes all sciences directed to the system-level of understanding of the environment, drawing especially upon such disciplines as meteorology, geophysics, oceanography, and ecology, and utilizing to the fullest knowledge and techniques developed in such fields as physics, chemistry, biology, mathematics and engineering as well as many social science disciplines, such as economics, such as economics, law, political science and public administration." The components of this discipline are not new, for they are drawn from existing areas of science within biology chemistry, physics, and geoscience. What is really new about environmental science, however, is it siewpoint - its orientation to global problems, its conception of the earth as a set of interlocking, interacting systems, and its interest in Man as a part of these systems.

• Korean Journal of Biological Psychiatry
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• v.19 no.2
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• pp.71-76
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• 2012

Objectives : Novelty seeking (NS) represents a dopaminergically modulated tendency toward frequent exploratory activity. Considering the reports showing the relationship between exploratory activity and amygdalar function and structure, and the fact that amygdala is one of the key structures that constitute the dopaminergic pathway in the brain, amygdala might be closely related to NS tendencies. Amygdalar subregional analysis method, which has the enhanced sensitivity compared to the volumteric approach would be appropriate in investigating the subtle differences of amygdalar structures among healthy individuals. The aim of the current study was to examine whether amygdalar subregional morphometric characteristics are associated with the NS tendencies in healthy adults using the amygdalar subregional analysis method. Methods : Twenty-six healthy adults (12 males, 14 females ; mean age $29.8{\pm}6.2$ years) were screened for eligibility. All subjects completed the Korean version of the Temperament and Character Inventory (TCI) and underwent high-resolution brain magnetic resonance imaging. Individuals were divided into 2 groups according to NS scores of the TCI. Results : Individuals of the high NS group had significantly larger laterobasal subregions in right amygdala, after adjustment with the brain parenchymal volumes. Sensitivity analyses for each potential confounding factor such as age, education years and Hamilton Depression Rating Scale (HDRS) scores demonstrated consistent results. Conclusions : This study suggests that NS differences are associated with the laterobasal subregion of the amygdala.

• Interdisciplinary Bio Central
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• v.3 no.1
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• pp.5.1-5.5
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• 2011

Introduction: Many signal transduction pathways mediate cell's behavior by regulating expression level of involved genes. Abnormal behavior indicates loss of regulatory potential of pathways, and this can be attributed to loss of expression regulation of downstream genes. Therefore, function of pathways should be assessed by activity of a pathway itself and relative activity between a pathway and downstream genes, simultaneously. Results and Discussion: In this study, we suggested a new method to assess pathway's function by introducing concept of 'responsiveness'. The responsiveness was defined as a relative activity between a pathway itself and its downstream genes. The expression level of a downstream gene as a function of an upstream pathway activation characterizes disease status. In this aspect, by using the responsiveness we predicted potential progress in cancer development. We applied our method to predict primary and metastatic status of melanoma cancer. The result shows that the responsiveness-based approach achieves better performance than using gene or pathway information alone. The mean of ROC scores in the responsiveness-based approach was 0.90 for GSE7553 data set, increased more than 40% compared to a gene-based method. Moreover, identifying the abnormal regulatory patterns between pathway and its downstream genes provided more biologically interpretable information compared to gene or pathway based approaches.

• Journal of Science and Technology Studies
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• v.16 no.1
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• pp.5-22
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• 2016

MERS(Middle East Respiratory Syndrome), an acute and infectious viral disease with high fatality sneaked in South Korea in May 2016. Although MERS is officially declared to be exterminated in Korea by the date of December 24, it aroused a great panic throughout the country and remained many tasks requiring sincere deliberations and innovative actions. This study starts to summarize all that had been happening during first 7 months since last May, reconsider the whole process in light of disaster paradigm, analyze the causes and tasks of such turmoil under the framework of social medicine. It is wrapped up with the visions and prospect of the social medicine, an interdisciplinary approach that takes into account the expert knowledge of academia, administrative knowledge of government, media knowledge from traditional/new media and lay knowledge of civil society.

• Journal of Families and Better Life
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• v.27 no.5
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• pp.43-57
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• 2009

This study analyzes the tendency for studies of children's manners in Korea. This research provides basic information for future research on the study of children's manners. I reviewed previous research during Mar.10~Apr. 30., 2009, and published articles that used terms such as 'ye-jul', 'yua ye-jul', 'jun-tong ye-jul', and 'yua-dare kyo yuk' as key-words provided by the National Assembly Library and Academic Information Center, and the terms were used for contents analysis. In the past, parents usually taught manners to their children at home, but now, most children learn etiquette at kindergarten and day care centers. A greater portion of the studies dealing with children's manners has been published since 2001. The experimental method was used for most of this research. Based on the results, I have made suggestion regarding the direction of future studies of children's manners. Research should investigate the value of children's manners and philosophy in future research. Based on the personal characteristics of each child and their understanding of the ecological environment, studies of children's manners require an interdisciplinary research approach or ecological research approach. These studies should continue to research in cooperation with kindergartens and day care centers. In addition, further research should focus on an effective teaching method or instructional media research of children's manners.