Asia-Pacific Journal of Business Venturing and Entrepreneurship
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v.14
no.3
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pp.169-183
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2019
Should a startup file for a patent subject to imitation in its quest to attract venture capital(VC) investors? Considering the US pharmaceutical biotechnology industry context, this paper attempts to answer this question by investigating the relations between the number of applied patents of startups, patent imitability, and the total amount of money the startups received as their first VC funding round. Data of 157 US-based pharmaceutical biotechnology startups founded in between 1995 and 2005 are analyzed. Empirical results from this study show that the number of applied patents is positively related to the total amount of money received at the time of the first funding round, and patent imitability is negatively related to the total amount of money received as first VC funding round. Nonetheless, the interaction term between the number of applied patents of startups and patent imitability came out as positive, raising interesting questions and implications for innovation-oriented startup entrepreneurs. The current study's empirical findings suggest that, in the pharmaceutical biotechnology sector, VC investors pay attention to the quantity and quality of the patents possessed by startups when they decide the level of funding. In particular, imitability of applied patents may not be a one-sided concept related to negative features such as the weak protectability of an invention. Rather, patent imitability may be a multi-facet element which also contains positive attractiveness of the startup's invention. Furthermore, it seems that the positive side of imitability can be augmented by the number of applied patents.
The purpose of this study was to analyze the change of body temperature and pain by application of Gaussian magnetic for the elderly delayed muscle pain. For the purpose, we selected 15 elderly women(age;$69.47{\pm}1.60$) and conducted repeated experiments. The Gaussian magnetic field area was divided into three areas (1000G, 1500G, 2000G). The applying arbitrarily manufactured magnetic field wristbands changes of body heat and pain before and after wearing Gaussian magnetic were measured and collected data were analyzed using SPSS 19.0. To examine the pre-and post-treatment differences by treatment areas, we conducted paired t-test. Group differences and interaction effects were analyzed using two-way ANOVA and Duncan post hoc tests. The significance level was set to ${\alpha}=.05$. The results are as follows. The change of body heat by the Gaussian magnetic field area showed significant differences in all three groups(P<.05). There were also significant differences in the results of group interactions and in the delayed muscle pain scale between groups(P<.05). The area with the largest difference appeared in the area of 1500G field. The 1000G-1500G Gauss field is considered to be the most ideal magnetic field for body heat and muscle pain changes. In conclusion, the Gaussian magnetic field of 1000G-1500G may affect body temperature and muscle pain in the elderly, and may have a significant impact on the quality of life in old age.
This study aimed to investigate the effects of participating in an aerobic exercise program three days a week and 50 minutes a day on dementia related factors and cognitive function in elderly women with mild dementia. For this, among 17 elderly women aged 65 and above, 10 elderly women were randomly assigned to the experimental group and 7 elderly wonmen to the control group. As a result of comparative analysis, conclusions were drawn as follows: There was a significant difference (p<.05) in the DHEA-s change between the two groups according to whether or not the aerobic exercise program was performed. Changes in cognitive function did not show any significant difference in the interaction effects of group, period, period${\times}$group. These results suggest that the aerobic exercise program did not show statistically significant effects on the dementia related factors and cognitive function changes of the elderly women with mild dementia. The reason for this is that the followings should be analyzed in more detail, but the lack of control on the daily life (diet) of the study subjects, which was considered as a limitation in this study, seems to be the biggest cause. Based on the results of this study, we hope that this study will be used as a basic data for improving the quality of dementia.
Lee, Jun Yeop;Lee, Myung Ho;Song, Yong Han;Lee, Jong In;Ohh, Sang Jip
Korean Journal of Poultry Science
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v.45
no.4
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pp.273-283
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2018
Two diet energy levels (high or low) and two bedding material (rice husk or saw dust) treatments were designed for either male or female slow-growing Korean meat-type chicken (Hanhyop 3) to make totally eight treatments for 11~75 d feeding trial. Body weight gain (BWG) were influenced by energy levels, sex of bird and bedding material type. There were interaction effect among those three factors. Feed intakes (FI) by male bird during each and overall periods were higher than those by female. Diet energy levels and bedding material affected the FI only during final 56~75 d period, of which FI of high energy diet was higher in male whereas that of low energy diet was higher in female. Although feed conversion ratio (FCR) was improved by high energy diet, the better FCR has dissipated during 41~75 d, when the most of overall BWG were achieved. Apparent total tract retention (ATTR) of nutrients were higher in male than those in female birds with exception on fat ATTR. Fat ATTR was improved when fed low energy diet regardless of the sex of birds. Both energy levels and sex of bird influenced the color of breast. Thiobarbituric acid reactive substances (TBARS) value of female thigh was higher than that of male. Levels of moisture and P in female thigh were lower although level of fat in female breast was higher than those in male, respectively. This study showed that diet energy levels for Hanhyop 3 chicken, especially during 41~75 d, should be differently formulated between male and female bird.
Pericarp thickness of vegetable corns such as sweet and waxy corn is one of the crucial traits, contributing to their edible quality. This study was carried out to compare the pericarp thickness of super sweet and waxy corn hybrids measured with kernel samples prepared using different methods at different grain filling periods. The samples comprised excised pericarp from dried, frozen (at $-4^{\circ}C$), and fresh kernels. Analysis of variance performed separately on super sweet and waxy corn hybrids indicated a significant three-way interaction among cultivars, kernel sample preparation methods, and days after pollination (DAP). Dried samples of super sweet corn hybrids presented reasonably stable pericarp thickness measurements during grain filling, while all the sample preparation methods fluctuated less as grains of waxy corn hybrids matured. Waxy corn is best consumed at around 24 days after pollination. Pericarp thickness of waxy kernel samples regardless of preparation methods investigated was the same at 24 DAP with a few exceptions. Overall, the common method of drying kernel samples before pericarp excision can provide reliable data for estimating the tenderness of vegetable corn hybrids.
Objective: The aim of the study was to find a possible association between the ${\beta}-$ and ${\kappa}-casein$ and ${\beta}-lactoglobulin$ genotypes and important milk physiochemical and technological characteristics such as acidity, alcohol stability, the contents of some minerals and the parameters of acid fermentation ability (FEA) in Czech Fleckvieh Cattle. Methods: Milk and blood samples were collected from 338 primiparous Czech Fleckvieh cows at the same stage of lactation. The genotypes of individual cows for ${\kappa}-casein$ (alleles A, B, and E) and ${\beta}-lactoglobulin$ (alleles A and B) were ascertained by polymerase chain reaction-restriction fragment length polymorphism, while their ${\beta}-casein$ (alleles $A^1$, $A^2$, $A^3$, and B) genotype was determined using melting curve genotyping analysis. The data collected were i) milk traits including active acidity (pH), titratable acidity (TA), alcohol stability (AS); calcium (Ca), phosphorus (P), sodium (Na), magnesium (Mg), and potassium (K) contents; and ii) yoghurt traits including active acidity (Y-pH), titratable acidity (Y-TA), and the counts of both Lactobacilli and Streptococci in 1 mL of yoghurt. A linear model was assumed with fixed effects of herd, year, and season of calving, an effect of the age of the cow at first calving and effects of the casein and lactoglobulin genotypes of ${\beta}-CN$ (${\beta}-casein$, CSN2), ${\kappa}-CN$ (${\kappa}-casein$, CSN3), and ${\beta}-LG$ (${\beta}-lactoglobulin$, LGB), or the three-way interaction between those genes. Results: The genetic polymorphisms were related to the milk TA, AS, content of P and Ca, Y-pH and Lactobacilli number in the fresh yoghurt. The CSN3 genotype was significantly associated with milk AS (p<0.05). The effect of the composite CSN2-CSN3-LGB genotype on the investigated traits mostly reflected the effects of the individual genes. It significantly influenced TA (p<0.01), Y-pH (p<0.05) and the log of the Lactobacilli count (p<0.05). Conclusion: Our findings indicate that the yoghurt fermentation test together with milk proteins genotyping could contribute to milk quality control and highlight new perspectives in dairy cattle selection.
Journal of the Korean Institute of Landscape Architecture
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v.47
no.3
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pp.71-80
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2019
The Fourth Industrial Revolution, centered on intelligence and information, began to take hold in 2016. This study uses virtual reality technology, which is the most popular technology of the Fourth Industrial Revolution. The purpose of this study is to explore a Virtual Walk-through method, which can be easily applied to landscape architecture. At present, virtual reality technology is widely used in the fields of games, emergency training, and architectural design. However, in the field of landscape architecture, it is still in the development stage. In addition, most of the traditional ways to display virtual reality use 2D images, but such methods have some limitations. Therefore, this research addresses the three stages of "design-exhibition-experience" and puts forward a new simple method called 'Virtual Walk-through' that breaks from traditional landscape design exhibitions. The results show that compared with traditional methods, virtual reality has many advantages, such as the freedom of experience, a diversity of viewing angles, information supply, interaction, etc. It can show high quality images and effects, which are suitable for landscape design. It provides an evaluation method for garden design that can be utilized in the future. It is simple and has value as it can reflect the method and the expected effects. Virtual reality technology can bring an infinite number of prospects to the development of landscape architecture.
This study attempts to understand the context of shared learning in the trading zone formed by teachers from different backgrounds and the process in which this shared learning varies in the educational context, focusing on the case of 'Woodwork Science Education Study Group.' To do this, data was collected through in-depth interviews with eight teachers who participated in the 'Woodworking Science Education Research Group' and analyzed their responses based on grounded theory. As a result, the causal conditions of the teachers' research group were 'various contexts of entering the trading zone' and the central phenomenon was 'encounter with learning in the trading zone.' Contextual conditions affecting this phenomenon were 'woodwork as a boundary object and individual transfiguration experience,' and action/interaction strategy was 'various efforts and influences in the field.' The intervention condition was 'practical effort and experience in educational field.' Final result in this model is 'the new practice of learning shared in the trading zone.' In selective coating, it was found that the practice of the teacher's research group appears as four types of' 'Extracurricular creative experience type,' 'career education type,' 'curricula education type,' and 'school management type.' The results of this study suggest that the shared learning and antonymous practice among teachers in the teachers' research group as trading zone do not only meet their learning needs but also lead to various teaching practices in the individual teachers' context of education and improve the diversity and quality of education.
Journal of the Korea Academia-Industrial cooperation Society
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v.19
no.12
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pp.938-943
/
2018
Thin nano-sized fibres were prepared by an electrospinning method. The spinning appratus consisted of pump for polymer injection, nozzle and nozzle rotus, and an aluminum plate collected the polymer fibers. Its surface was chemically modified for selective improved adsorption of carbon monoxide at indoor level. The chemical activation enabled to form the fibres 250-350 nm in thickness with pore sizes distributed between 0.6 and 0.7 nm and an average specific surface area of $569m^2/g$. The adsorption capacities of pure (100%) and indoor (0.3%) $CO_2$, of which level frequently appears, at the ambient condition were improved from 1.08 and 0.013 to 2.2 and 0.144 mmol/g, respectively. It was found that the adsorption amount of $CO_2$ adsorbed by the chemically activated carbon nanofiber prepared through chemical activation would vary depending on the ratio of specific surface area and micropores. In particular, chemical interaction between adsorbent surface and gas molecules could enhance the selective capture of weak acidic $CO_2$.
It is no longer special for the gaming industry to provide a community to promote their games. Much prior research related to the community also focuses on the spread of community influence and its importance. In particular, the user community in the gaming industry is having a big impact on the company's revenue creation beyond the simple level of information provision and promotion of friendship. Therefore, providing a community at the same time as the game is released is becoming a common trend in the gaming industry This study attempted to explore factors influencing the design of more effective communities under the assumption that the user community will influence the loyalty of mobile games. The design elements of the community suggested in this study are the provision of interaction tools between users, the provision of information, and communication between the game maker and the users. This study aims to confirm that these design factors affect customer loyalty by reinforcing user empathy and trust in the game within the user community. After collecting data from 251 users active in the mobile game user community, the model presented in this study was empirically analyzed. As a result, the design elements of the game community suggested in this study were found to affect customer loyalty by strengthening the empathy for the game and the trust in the game developer.
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