• International Journal of Naval Architecture and Ocean Engineering
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• v.4 no.1
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• pp.57-70
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• 2012

This article presents a numerical investigation concerning the effect of two kinds of axially progressing internal flows (namely, upward and downward) on fluid.structure interaction (FSI) dynamics about a marine riser model which is subject to external shear current. The CAE technology behind the current research is a proposed FSI solution, which combines structural analysis software with CFD technology together. Efficiency validation for the CFD software was carried out first. It has been proved that the result from numerical simulations agrees well with the observation from relating model test cases in which the fluidity of internal flow is ignorable. After verifying the numerical code accuracy, simulations are conducted to study the vibration response that attributes to the internal progressive flow. It is found that the existence of internal flow does play an important role in determining the vibration mode (/dominant frequency) and the magnitude of instantaneous vibration amplitude. Since asymmetric curvature along the riser span emerges in the case of external shear current, the centrifugal and Coriolis accelerations owing to up- and downward internal progressive flows play different roles in determining the fluid.structure interaction response. The discrepancy between them becomes distinct, when the velocity ratio of internal flow against external shear current is relatively high.

• Genomics & Informatics
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• v.18 no.4
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• pp.38.1-38.9
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• 2020

Chronotype is an important moderator of psychiatric illnesses, which seems to be controlled in some part by genetic factors. Clock genes are the most relevant genes for chronotype. In addition to the roles of individual genes, gene-gene interactions of clock genes substantially contribute to chronotype. We investigated genetic associations and gene-gene interactions of the clock genes BHLHB2, CLOCK, CSNK1E, NR1D1, PER1, PER2, PER3, and TIMELESS for chronotype in 1,293 healthy Korean individuals. Regression analysis was conducted to find associations between single nucleotide polymorphism (SNP) and chronotype. For gene-gene interaction analyses, the quantitative multifactor dimensionality reduction (QMDR) method, a nonparametric model-free method for quantitative phenotypes, were performed. No individual SNP or haplotype showed a significant association with chronotype by both regression analysis and single-locus model of QMDR. QMDR analysis identified NR1D1 rs2314339 and TIMELESS rs4630333 as the best SNP pairs among two-locus interaction models associated with chronotype (cross-validation consistency [CVC] = 8/10, p = 0.041). For the three-locus interaction model, the SNP combination of NR1D1 rs2314339, TIMELESS rs4630333, and PER3 rs228669 showed the best results (CVC = 4/10, p < 0.001). However, because the mean differences between genotype combinations were minor, the clinical roles of clock gene interactions are unlikely to be critical.

• Tunnel and Underground Space
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• v.20 no.1
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• pp.58-64
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• 2010

GLI model was verified to consider the interaction between a ground and a tunnel lining and to rationally reduce the ground load acting on the secondary lining(concrete lining) of a tunnel. In this study, the economy and the construction condition of tunnel concrete linings designed by a conventional frame model at Lot O of OO line were highly enhanced through a field design change using GLI model. For a few safe considerations, not only about 50% saving of reinforcing steel could reduce the material cost but also the wide space between bars could make it easy to pour concrete mix without voids. There was large saving effect of reinforcing steel for poor ground conditions because Terzaghi's load used in the conventional frame model produces too much high loads for those conditions.

• Journal of Engineering Education Research
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• v.1 no.1
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• pp.57-79
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• 1998

In this paper, I advocate interactive model which treats science and technology as distinguishable subcultures each with their own bodies of lore and competence against the traditonal hierachical model which treats technology as applied science. For engineering science which is a component in technology as knowledge, I count design as the core part of engineering and discuss the characteristic of engineering design. I also critically assess the models of technological knowledge change, Khunian model and variation-selection model to understand the relation between science and technology. I propose a model that science and technology interaction is mediated interaction. I only outline the plausibility of this model. Industrial research is a modern form of the interaction between science and technology. I discuss Reich who focused on the broad background of industrial research and MeyerThurow who has microperspective in industrial research. The conclusion I draw from the discussion, is that through industiral research, the science-technology interaction become more structured and autonomous, and the scientists and engineers become simply patrs of the structure of industrial research rather than the personal subject.

• The Journal of Society for e-Business Studies
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• v.21 no.4
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• pp.119-136
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• 2016

Precedent studies revealed that success of IT project strongly depends on the competency of PMO(project management offices), however, there are only few studies which show the importance of PMO competency. In this study, we will suggest an evaluation model of IT PMO competency using the Pentagon Model which is a tool to assess the performance of project organization, and the Analytic Hierarchy Process. We classified effect factor of PMO competency into 25 items in 5 fields such as Structure, Technology, Culture, Interaction, Social Relations and Networks based on pentagon model, also analysis of criticality between the effect factors was conducted by AHP. The study result shows 3 factors of Structure were included in the top 10, while 2 factors of Technology, Culture, Interaction were included separately. In terms of Social Relations and Networks, only 1 factor was included in the top 10. Therefore Structure of PMO should be aggressively considered for the successful IT project.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.37 no.12
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• pp.1559-1565
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• 2013

This study aims to investigate the dynamic interaction characteristics between Maglev vehicles and an elevated guideway. A more detailed model for the dynamic interaction of the vehicle/guideway is proposed. The proposed model incorporates a 3D full vehicle model based on prototyping, flexible guideway by a modal superposition method, and levitation electromagnets including the feedback controller into an integrated model. The proposed model was applied to an urban transit Maglev developed for a commercial application to analyze the dynamic response of the vehicle and guideway, and the effect of the surface roughness of the rail, mid-span guideway deflections, and air gap variations are then investigated from the numerical simulation.

• Journal of the Korean BIBLIA Society for library and Information Science
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• v.30 no.2
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• pp.145-166
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• 2019

While a significant number of user-related models have been presented in Human Information Behavior (HIB) research community, the basic assumption of the present study is most of those models including information interaction models are multi-domain models associated with comprehensive research components. Based on such an assumption, this study discusses the shortcomings of multi-domain models and proposes the need to present a new type of model. Accordingly, the study elaborates four essential models of HIB reach community and presents a new type of model based on Specific Domain Focus Modeling (SDFM). As an example of such modeling, this study presents the present author's information retrieval interaction model based on the degree of connections between systems and information resources.

• Coupled systems mechanics
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• v.7 no.6
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• pp.649-668
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• 2018

In this paper, we present a numerical model for fluid-structure interaction between structure built of porous media and acoustic fluid, which provides both pore pressure inside porous media and hydrodynamic pressures and hydrodynamic forces exerted on the upstream face of the structure in an unified manner and simplifies fluid-structure interaction problems. The first original feature of the proposed model concerns the structure built of saturated porous medium whose response is obtained with coupled discrete beam lattice model, which is based on Voronoi cell representation with cohesive links as linear elastic Timoshenko beam finite elements. The motion of the pore fluid is governed by Darcy's law, and the coupling between the solid phase and the pore fluid is introduced in the model through Biot's porous media theory. The pore pressure field is discretized with CST (Constant Strain Triangle) finite elements, which coincide with Delaunay triangles. By exploiting Hammer quadrature rule for numerical integration on CST elements, and duality property between Voronoi diagram and Delaunay triangulation, the numerical implementation of the coupling results with an additional pore pressure degree of freedom placed at each node of a Timoshenko beam finite element. The second original point of the model concerns the motion of the outside fluid which is modeled with mixed displacement/pressure based formulation. The chosen finite element representations of the structure response and the outside fluid motion ensures for the structure and fluid finite elements to be connected directly at the common nodes at the fluid-structure interface, because they share both the displacement and the pressure degrees of freedom. Numerical simulations presented in this paper show an excellent agreement between the numerically obtained results and the analytical solutions.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.26 no.5B
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• pp.481-488
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• 2006

This paper suggests a novel approach of integrating the quasi-distributed watershed model SWAT with the fully-distributed groundwater model MODFLOW. Since the SWAT model has semi distributed features, its groundwater components hardly considers distributed parameters such as hydraulic conductivity and storage coefficient. Generating a detailed representation of groundwater recharge, head distribution and pumping rate is equally difficult. To solve these problems, the method of exchanging the characteristics of the hydrologic response units (HRUs) in SWAT with cells in MODFLOW by fully combined manner is proposed. The linkage is completed by considering the interaction between the stream network and the aquifer to reflect boundary flow. This approach is provisionally applied to Gyungancheon basin in Korea. The application demonstrates a combined model which enables an interaction between saturated zones and channel reaches. This interaction plays an essential role in the runoff generation in the Gyungancheon basin. The comprehensive results show a wide applicability of the model which represents the temporal-spatial groundwater head distribution and recharge.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.5
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• pp.1803-1808
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• 2012

This study aimed to investigate the effects of Ser/Cys polymorphism in hOGG1 gene, Arg/Pro polymorphism in p53 gene, smoking and their interactions on the development of lung cancer. Ser/Cys polymorphism in hOGG1 and Arg/Pro polymorphism in p53 among 124 patients with lung cancer and 128 normal people were detected using PCR-RFLP. At the same time, smoking status was investigated between the two groups. Logistic regression was used to estimate the effects of Ser/Cys polymorphism and Arg/Pro polymorphisms, smoking and their interactions on the development of lung cancer. ORs (95% CI) of smoking, hOGG1 Cys/Cys and p53 Pro/Pro genotypes were 2.34 (1.41-3.88), 2.12 (1.03-4.39), and 2.12 (1.15-3.94), respectively. The interaction model of smoking and Cys/Cys was super-multiplicative or multiplicative, and the OR (95% CI) for their interaction item was 1.67 (0.36 -7.78). The interaction model of smoking and Pro/Pro was super-multiplicative with an OR (95%CI) of their interaction item of 5.03 (1.26-20.1). The interaction model of Pro/Pro and Cys/Cys was multiplicative and the OR (95%CI) of their interaction item was 0.99 (0.19-5.28). Smoking, hOGG1 Cys/Cys, p53 Pro/Pro and their interactions may be the important factors leading to the development of lung cancer.