• Title/Summary/Keyword: integrity assessment

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Management of Multiple Ligament Injured Knee (슬관절 다발성 인대 손상의 치료)

  • Sim, Jae-Ang;Lee, Beom-Koo
    • Journal of Korean Orthopaedic Sports Medicine
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    • v.12 no.1
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    • pp.16-23
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    • 2013
  • Multiple ligament knee injury is defined as rupture to at least two of the four major knee ligament structures. Three or four knee ligament injury results in knee dislocation as complete disruption of the integrity of the tibiofemoral articulation. In multiple ligament knee injury, vascular and neurologic assessment should be performed meticulously and systematically. Emergency surgery should be needed if arterial injury is suspected. Surgical treatment rather than conservative management should be done and early surgery might be better than delayed surgery. Reconstruction of ACL and PCL, repair or reconstruction of MCL, and reconstruction of posterolateral corner are recommended, although many debates have occurred. Multiple ligament knee injury requires more aggressive management than single ligament knee injury.

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Functional Assessment of Frequency of a Commercial Shampoo for Normal Canine Skin (개에서 피부세정제 적용빈도가 정상피부에 미치는 영향)

  • Yu, Jong-Won;Shin, Hee-Ju;Bae, Seulgi;Choi, Sungwon;Oh, Tae-Ho
    • Journal of Veterinary Clinics
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    • v.30 no.4
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    • pp.283-287
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    • 2013
  • Canine skin is a highly dynamic organ that is constantly adapted to changes in its environment. It provides structural, sensory, immunologic, and physiologic functions and contributes an essential barrier function against potential environmental insults. We assessed the changes of canine skin hydration, pH, and protein contents by noninvasive method according to the frequency of application with canine commercial shampoo. Canine commercial shampoo was applied topically every other day, 5 days, and 8 days on different sites, respectively in 8 dogs. Saline-applied site was as a control. Skin hydration was increased and skin surface pH was decreased significantly in canine commercial shampoo-applied site every other day (p < 0.05). Also, skin protein concentration measured by D-squame$^{(R)}$ tape stripping method was increased significantly in canine commercial shampoo-applied site every other day (p < 0.05). There were alterations on every 5 days and 8 days, but not significantly. These results may be recognized that the frequent use of canine commercial shampoo cause abnormalities of the skin barrier function and alteration of stratum corneum integrity/cohesion. Consequently it was suggested that bathing the dog with canine commercial shampoo was appropriate every 5 or 8 days.

A Study on the Effects on Low Cycle Fatigue Life of a High Pressure Turbine Nozzle due to the Perturbation of Crystal Orientation of Grain of DS Materials (일방향 응고 재료의 결정립 성장 방향 섭동이 고압터빈 노즐 저주기 피로 수명에 미치는 영향에 대한 연구)

  • Huh, Jae Sung;Kang, Young Seok;Rhee, Dong Ho
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.40 no.7
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    • pp.653-658
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    • 2016
  • High pressure components of a gas turbine engine are generally made of nickel-base superalloys, using precision casting process due to complicated geometries with intricate channels and cooling holes. Turbine components manufactured from directionally solidified and single crystal materials have columnar grains; however, it is found that the crystals do not grow in its preferred direction, although the orientation can be controlled. This anisotropy can lead to the variations of elastic and Hill's parameters in constitutive equations, and they alter stress distributions and the low cycle fatigue life. We aims to evaluate the effects of perturbed crystal orientations on the structural integrity of a directionally solidified nozzle using low cycle fatigue life. We also attempt to show the necessity for the control of allowed manufacturing errors and stochastic analysis. Our approaches included conjugate heat transfer and structural analysis, along with low cycle fatigue life assessment.

FIV Analysis of SG Tubes for Various TSP Locations (튜브 지지판 재배치에 따른 유체유발진동 특성 해석)

  • Kim, Hyung-Jin;Park, Chi-Yong;Park, Myoung-Ho;Ryu, Ki-Whan
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.15 no.9 s.102
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    • pp.1009-1015
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    • 2005
  • Fluid-elastic instability and turbulence excitation for an under developing steam generator are investigated numerically. The stability ratio and the amplitude of turbulence excitation are obtained by using the $PIAT^{(R)}$ (program for integrity assessment of steam generator tube) code from the information on the thermal-hydraulic data of the steam generator. The aspect ratio, the ratio between the height of U-tube from the upper most tube support Plate (h) and the width of two vertical portion of U-tube (w), is defined for geometric parameter study. Several aspect ratios with relocation of tube support plates are adopted to study the effects on the mode shapes and characteristics of flow-induced vibration. When the aspect ratio exceeds value of 1, most of the mode shapes at low frequency are generated at the top of U-tube. It makes very high value of the stability ratio and the amplitude of turbulent excitation as well. We can consider that the local mode shape at the upper side of U-tube will develop the wear phenomena between the tube and the anti-nitration bars such as vortical, horizontal, and diagonal strips. It turns out that the aspect ratio reveals very important parameter for the design stage of the steam generator. The appropriate value of the aspect ratio should be specified and applied.

INHERENT SAFETY ANALYSIS OF THE KALIMER UNDER A LOFA WITH A REDUCED PRIMARY PUMP HALVING TIME

  • Chang, W.P.;Kwon, Y.M.;Jeong, H.Y.;Suk, S.D.;Lee, Y.B.
    • Nuclear Engineering and Technology
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    • v.43 no.1
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    • pp.63-74
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    • 2011
  • The 600 MWe, pool-type, sodium-cooled, metallic fuel loaded KALIMER-600 (Korea Advanced LiquId MEtal Reactor, 600 MWe) has been conceptually designed with an emphasis on safety by self-regulating (inherent/intrinsic) negative reactivity feedback in the core. Its inherent safety under the ATWS (Anticipated Transient Without Scram) events was demonstrated in an earlier study. Initiating events of an HCDA (Hypothetical Core Disruptive Accident), however, also need to be analyzed for assessment of the margins in the current design. In this study, a hypothetical triple-fault accident, ULOF (Unprotected Loss Of Flow) with a reduced pump halving time, is investigated as an initiator of a core disruptive accident. A ULOF with insufficient primary pump inertia may cause core sodium boiling due to a power-to-flow mismatch. If the positive sodium reactivity resulting from this boiling is not compensated for by other intrinsic negative reactivity feedbacks, the resulting core power burst would challenge the fuel integrity. The present study focuses on determination of the limit of the pump inertia for assuring inherent reactivity feedback and behavior of the core after sodium boiling as well. Transient analyses are performed with the safety analysis code SSC-K, which now incorporates a new sodium boiling model. The results show that a halving time of more than 6.0 s does not allow sodium boiling even with very conservative assumptions. Boiling takes place for a halving time of 1.8 s, and its behavior can be predicted reasonably by the SSC-K.

A Study on the Reliability/Safety assessment and improvement of USN Gateway for Train Control (열차제어를 위한 USN Gateway 신뢰성, 안전성 평가 및 향상에 관한 연구)

  • Sin, Duc-Ko;Jo, Hyun-Jeong;Shin, Kyeng-Ho;Song, Yong-Soo
    • Journal of the Korean Society for Railway
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    • v.14 no.5
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    • pp.416-424
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    • 2011
  • The recent development of USN (Ubiquitous Sensor Network) technology has broadened its applications to many fields of industry. The USN technology enables the system to monitor and control the status of distributed sensor nodes based on the low-powered communications. Applying the USN in the train control domain, the operational efficiency can be enhanced, where the reliability and the safety of the system are the key challenges. This paper suggests the system design for evaluating and improving the reliability and safety of the gateway, which is a USN component that manages the radio network among the sensors and collects the information from them. For this purpose, the reliability and the level of safety integrity of a general gateway have been predicted quantitatively and the supplementary design has been proposed for the selected week points. The verification on the reliability and the safety of the improved gateway according to the related standards has been followed. With the results of the study, the applicability of USN gateway for train control systems has been reviewed.

A Study on the Sloshing Impact Response Analysis for the Insulation System of Membrane Type LNG Cargo Containment System (LNG 탱크 방열구조의 슬로싱 충격 응답 해석법에 관한 연구)

  • Nho, In-Sik;Ki, Min-Seok;Lee, Jae-Man;Kim, Sung-Chan
    • Proceedings of the Computational Structural Engineering Institute Conference
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    • 2011.04a
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    • pp.531-538
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    • 2011
  • To ensure the structural integrity of membrane type LNG tank, the rational assessment of impact pressure and structural responses due to sloshing should be preceded. The sloshing impact pressures acting on the insulation system of LNG tank are typical irregular loads and the structural responses caused by them also very complex behaviors including fluid structure interaction. So it is not easy to estimate them accurately and huge time consuming process would be necessary. In this research, a simplified method to analyze the dynamic structural responses of LNG tank insulation system under pressure time histories obtained by sloshing model test or numerical analysis was proposed. This technique basically based on the concept of linear combination of the triangular response functions which are obtained by the transient response analysis under the unit triangular impact pressure acting on structures in time domain. The validity of suggested method was verified through the example calculations and applied to the structural analysis of real Mark III type insulation system using the sloshing impact pressure time histories obtained by model test.

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Gene Expression Profile of Zinc-Deficient, Homocysteine-Treated Endothelial Cells

  • Kwun, In-Sook;Beattie, John H.
    • Preventive Nutrition and Food Science
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    • v.8 no.4
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    • pp.390-394
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    • 2003
  • In the post-genome period, the technique for identifying gene expression has been progressed to high throughput screening. In the field of molecular nutrition, the use of screening techniques to clarify molecular function of specific nutrients would be very advantageous. In this study, we have evaluated Zn-regulated gene expression in Zn-deficient, homocystein-treated EA.hy926 cells, using cDNA microarray, which can be used to screen the expression of many genes simultaneously. The information obtained can be used for preliminary assessment of molecular and signaling events modulated by Zn under pro-atherogenic conditions. EA.hy926 cells derived from human umbilical vein endothelial cells were cultured in Zn-adequate (control, 15 $\mu$M Zn) or Zn-deficient (experimental, 0 $\mu$M Zn) Dulbecco's MEM media under high homocysteine level (100 $\mu$M) for 3 days of post-confluency. Cells were harvested and RNA was extracted. Total RNA was reverse-transcribed and the synthesized cDNA was labeled with Cy3 or Cy5. Fluorescent labeled cDNA probe was applied to microarray slides for hybridization, and the slide was then scanned using a fluorescence scanner. The expression of seven genes was found to be significantly decreased, and one significantly increased, in response to treatment of EA.hy926 cells with Zn-deficient medium, compared with Zn-supplemented medium. The upregulated genes were oncogenes and tumor suppressor genes, cell cycle-related genes and transporter genes. The down-regulated gene was RelB, a component of the NF-kappaB complex of transcription factors. The results of this study imply the effectiveness of cDNA microarray for expression profiling of a singly nutrient deficiency, namely Zn. Furthur study, using tailored-cDNA array and vascular endothelial cell lines, would be beneficial to clarify the molecular function of Zn in atherosclerosis, more in detail.

Study on Crisis Conflict Culture Communication : Focusing on Information Specificity in SNS (위기갈등문화에 대한 소통방식 연구 :SNS 메시지 구체성을 중심으로)

  • Li, Xiao-Fan;Kim, Jung Kyu
    • The Journal of the Convergence on Culture Technology
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    • v.6 no.2
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    • pp.251-256
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    • 2020
  • Based on the development of SNS in Mobile and Internet, crisis management is regarded as an important issue that determines the rise and fall of businesses. This study aims to contribute to more efficient implementation of crisis management messages by examining the relationship between the strategy of crisis management communication and the level of specificity of the message. The study found that consumers evaluated the crisis-hit company's acceptance communication strategy to show a higher level of integrity, reliability and appropriateness than the defensive strategy. However, this main effect is mediated by the specificity (high specificity vs. low). Specifically, consumers' assessment of crisis management messages and information-seeking behavior were found to be most favorable when used in a mixture of acceptance strategies and high specificity. Conversely, the lowest effect was the combination of defense strategy and high specificity. Based on these results, the theoretical discussions is described for crisis management practitioners of enterprises and organizations.

Design of Network-based AIS Reference Station System (네트워크 기반 AIS 기준국 시스템 설계)

  • Seo, Ki-Yeol;Park, Sang-Hyun;Jeong, Ho-Cheol;Cho, Deuk-Jae
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.14 no.4
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    • pp.824-830
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    • 2010
  • In order to prepare for increasing performance requirement for Differential Global Navigation Satellite System (DGNSS) services of International Maritime Organization (IMO) and International Association of Lighthouse Authorities (IALA), this paper focuses on design of network-based Automatic Identification System (AIS) reference station system that can perform the functionality of Differential Global Positioning System (DGPS) reference station in an AIS base station system. AIS base station receives the differential corrections from the DGPS reference station, and it is not a method for transmitting the received differential corrections to onboard AIS units, but it is a method for generating the optimized differential corrections for onboard AIS units in AIS coverage. Therefore this paper proposes an algorithm for generating the differential corrections at AIS reference station, and performs the performance assessment of the proposed algorithm based on DGPS correction data measured from a DGPS reference station. Finally this paper discusses the test results and efficiency of the proposed system.