• 한국자기학회:학술대회 개요집
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• 한국자기학회 2003년도 하계학술연구발표회 및 한.일 공동심포지엄
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• pp.44-45
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• 2003

• 대한두경부종양학회지
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• 제23권1호
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• pp.21-25
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• 2007

Background：Squamous cell carcinoma(SCC)of the palatine tonsils represents approximately 15-23% of all intraoral SCC. The most frequently reported risk factors for oropharyngeal cancer are smoking and alcohol. In a recent overview of HPV and tonsillar squamous cell carcinoma(TC), 51% contained HPV DNA, and HPV-16 being the most frequent type. We aimed to clarify whether HPV directly effects on the oncogenesis and biologic behavior of TC by comparison with infection prevalence, and physical status of virus. Material and Method：We used HPV genotyping DNA chip(Biocore, Korea, Seoul) arrayed by multiple oligonucleotide probes of L1 sequence of 26 types of HPV and HPV genotypes are identified by fluorescence scanner. The copy numbers of HPV E2 and E6 open reading frames(ORF) were assessed using a TaqMan-based 5'-exonuclease quantitative real-time PCR assay. The ratio of E2 to E6 copy numbers was calculated to determine the physical status of HPV-16 viral gene. Results：We observed a significant difference in HPV prevalence between 52 TCs and 69 CFTs(73.1% vs. 11.6%), and most of the HPVs were type 16(87.2%)and non-episomal(94.1%) state. Conclusions：This study regarding HPV infection prevalence and mechanism in the largest population of palatine tonsillar squamous cell carcinoma with chronic follicular tonsillitis revealed significant difference pf HPV prevalence between TC and CFT. Most of HPV were 16 type and integrated or mixed, HPV-16 integration could be directly related to tonsillar carcinogenesis.

• ETRI Journal
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• 제34권1호
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• pp.138-141
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• 2012

This letter proposes a real-time digital image stabilization system for cell phone cameras without the need for frame memory. The system post-processes an image captured with a safe shutter speed using an adaptive denoising filter and a global color correction algorithm. This system can transfer the normal brightness of an image previewed under long exposure to the captured image making it bright and crisp with low noise. It is even possible to take photos in low-light conditions. By not needing frame memory, the approach is feasible for integration into the size-constrained image sensors of cell phone cameras.

• 전자공학회논문지S
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• 제35S권3호
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• pp.9-18
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• 1998

For constructionof the next generation satellite B-ISDN/ATM networks considering integration with terrestrial information infrastructure networks, various high speed and wideband satellites with be launched and they will make used of frequency reue techniques for efficient management of limited frequency resource. Therefore, CCI(Co-Channel Interference) inherent in frequency reuse will be a dominant factor in performance degradation of satellite networks. This paper alanyzes the ATM cell transmission performance degradation caused by CCI. The satellite link, including up-link and down-link thermal noise, CCI, and nonlinear satellite transponder, is modeled and interleaving technique is used for compensating the ATM cell transmission performance degradation caused by burst error of satellite link. First, each satellite link subsystem is analyzed in detail and then end-to-end ATM cell transmission performance is evaluated with BER and CLR. Specifically, ATMcell transmission performance degradation caused by CCI is evaluated in detail.

• 한국진공학회지
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• 제12권S1호
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• pp.33-35
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• 2003

The electrooptic properties of the reflected light in a reflective mode, $45^{\circ}C$twisted nematic liquid crystal (TNLC) cell were investigated in the voltage regions near and away from the Freedericksz transition threshold. The measured reflectivity away from the threshold voltage ($V_th$) could not be described by the model which assurnes a constant tilt angle as well as a linearized distribution of twist angle across the cell, although the data are well fitted near $V_th$. We found that in the voltage region away from $V_th$, the model considering the distributions of the tilt angle and the twist angle should be applied for the calculation of the reflectivity. The director-axis distributions were obtained from the numerical integration of the Euler-Lagrange equation.

• 한국전산구조공학회논문집
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• 제13권4호
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• pp.485-500
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• 2000

본 논문에서는 element-free Galerkin(EFG) 방법에 기반한 적응적 정적균열진전해석기법을 제시하였다. 균열진전 매단계마다 적응적해석을 수행함으로써 전체 해석의 일관성과 정밀성을 동시에 확보할 수 있었다. 균열진전과정에 있어서의 적응적해석은 산정된 오차지표에 따라 적분을 위한 격자구조에 따라 절점을 추가하고 소거하는 과정을 통해 구현되었다. 이 때 사용된 오차지표는 원 EFG해석결과 얻어진 응력과 절점응력을 다시 투영한 응력의 차에 의해 얻어졌다. 제안된 해석기법의 타당성과 효용성을 수치예제에 의해 검증하였다. 그 결과 제안된 해석기법이 균열진전해석시 효율적으로 적용될 수 있음을 보였다.

• 대한전기학회논문지:전기기기및에너지변환시스템부문B
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• 제51권5호
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• pp.242-248
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• 2002

It is important to develop new effective technologies to increase the interruption capacity and to reduce the size of a UB(Gas Circuit Breakers). Major design parameters such as nozzle geometries and interrupting chamber dimensions affect the cooling of the arc and the breaking performance. But it is not easy to test real GCB model in practice as in theory. Therefore, a simulation tool based on a computational fluid dynamics(CFD) algorithm has been developed to facilitate an optimization of the interrupter. Special attention has been paid to the supersonic flow phenomena between contacts and the observation of hat-gas flow for estimating the breaking performance. However, there are many difficult problems in calculating the flow characteristics in a GCB such as shock wave and complex geometries, which may be either static or in relative motion. Although a number of mesh generation techniques are now available, the generation of meshes around complicated, multi-component geometries like a GCB is still a tedious and difficult task for the computational fluid dynamics. This paper presents the CFD program using CFB-CAD integration technique based on Cartesian cut-cell method, which could reduce researcher's efforts to generate the mesh and achieve the accurate representation of the geometry designed by a CAD tools.

• 한국미생물·생명공학회지
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• 제29권1호
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• pp.1-11
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• 2001

Lactic acid bacteria (LAB) are widely used for various food fermentation. With the recent advances in modern biotechnology, a variety of bio-products with the high economic values have been produced using microorganisms. For molecular cloning and expression studies on the gene of interest, E. coli has been widely used mainly because vector systems are fully developed. Most plasmid vectors currently used for E, coli carry antibiotic-resistant markers. As it is generally believed that the antibiotic resistance markers are potentially transferred to other bacteria, application of the plasmid vectors carrying antibiotic resistance genes as selection markers should be avoided, especially for human consump-tion. By contrast, as LAB have some desirable traits such that the they are GRAS(generally recognized as safe), able to secrete gene products out of cell, and their low protease activities, they are regarded as an ideal organism for the genetic manipulation, including cloning and expression of homologous and heterologous genes. However, the vec-tor systems established for LAB are stil insufficient to over-produce gene products, stably, limiting the use of these organisms for industrial applications. For a past decade, the two popular plasmid vectors, pAM$\beta$1 of Streptococcus faecalis and pGK12 theB. subtilis-E. coli shuttle vector derived from pWV01 of Lactococcus lactis ssp. cremoris wg 2, were most widely used to construct efficient chimeric vectors to be stably maintained in many industrial strains of LAB. Currently, non-antibiotic markers such as nisin resistance($Nis^{r}$ ) are explored for selecting recombi-nant clone. In addition, a gene encoding S-layer protein, slp/A, on bacterial cell wall was successfully recombined with the proper LAB vectors LAB vectors for excretion of the heterologous gene product from LAB Many food-grade host vec-tor systems were successfully developed, which allowed stable integration of multiple plasmid copies in the vec-mosome of LAB. More recently, an integration vector system based on the site-specific integration apparatus of temperate lactococcal bacteriophage, containing the integrase gene(int) and phage attachment site(attP), was pub-lished. In conclusion, when various vector system, which are maintain stably and expressed strongly in LAB, are developed, lost of such food products as enzymes, pharmaceuticals, bioactive food ingredients for human consump-tion would be produced at a full scale in LAB.

• Journal of Power Electronics
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• 제11권2호
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• pp.202-210
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• 2011

Polymer electrolyte membrane (PEM) fuel cell is one of the popular renewable energy sources and widely used in commercial medium power areas from portable electronic devices to electric vehicles. In addition, the increased integration of the PEM fuel cell with power electronics, dynamic loads, and control systems requires accurate electrical models and simulation methods to emulate their electrical behaviors. Advancement in parallel computation techniques, various real-time simulation tools, and smart power hardware have allowed the prototyping of novel apparatus to be investigated in a virtual system under a wide range of realistic conditions repeatedly, safely, and economically. This paper builds up advancements of optimized model constructions for a fuel cell stack system on a real-time simulator in the view points of improving dynamic model accuracy and boosting computation speed. In addition, several considerations for a power hardware-in-the-loop (PHIL) simulation are provided to electrically emulate the PEM fuel cell stack system with power facilities. The effectiveness of the proposed PHIL simulation method developed on Opal RT's RT-Lab Matlab/Simulink based real-time engineering simulator and a programmable power supply is verified using experimental results of the proposed PHIL simulation system with a Ballard Nexa fuel cell stack.

• Journal of information and communication convergence engineering
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• 제14권1호
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• pp.26-34
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• 2016

The alignment of DNA sequences is one of the important processes in the field of bioinformatics. The Smith-Waterman algorithm (SWA) performs optimally for aligning sequences but is computationally expensive. Field programmable gate array (FPGA) performs the best on parameters such as cost, speed-up, and ease of re-configurability to implement SWA. The performance of FPGA-based SWA is dependent on efficient cell-basic implementation-unit design. In this paper, we present an optimized systolic cell design while avoiding oversimplification, very large-scale integration (VLSI)-level design, and direct mapping of iterative equations such as previous cell designs. The proposed design makes efficient use of hardware resources and provides portability as the proposed design is not based on gate-level details. Our cell design implementing a linear gap penalty resulted in a performance improvement of 32× over a GPP platform and surpassed the hardware utilization of another implementation by a factor of 4.23.