• Title/Summary/Keyword: injecting technology

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A Study on Radio-Protection Mechanism of Platelet Cells After Injection of Alliin (알리인 투여 후 혈소판의 방사선 방어기전 연구)

  • Ji, Tae-Jeong
    • Journal of radiological science and technology
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    • v.33 no.3
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    • pp.185-192
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    • 2010
  • Platelets originating from Megakaryocyte are sensitive to radiation along with white blood cells, and thus these platelets are used as an index of radiation hazard as they decrease in advance. Thus, when there is a scarcity of platelets, dot hemorrhage occurs and it leads to decrease of blood corpuscle and a decline in immunity. In particular, when 4~6 Gy whole body irradiation is received, after three weeks, the platelets will decrease to the lowest level, which can be a cause of death by bleeding and anemia. Therefore, this study tried to identify the mechanism of platelet damage and protection effect. The protection substance used in the experiment is Alliin, which is a component of garlic, and it was observed by an Transmission Electron Microscope(TEM) after its injection to the rat's tail vein. In the study, it was found that the cell membrane was severely damaged in a 10-day progressed platelet organ after receiving 5 Gy irradiation. It billowed as balloon-like figure and the glycocalyx became hyperplasia. The minute organ was damaged to the point that it was beyond recognition in a 20-day progressed platelet organ after receiving irradiation, and the cytoplasmic contents were exposed to epilepsy parts and outrageously damaged. Furthermore, the form of granules could also not be observed. A hole was formed in the middle, and the damaged organ was found in a 30-day progressed platelet. However, the form of granules was consistently maintained in the experiment group injecting Alliin, as with the control group, and there was no damage to the cell membrane recognized. Thus, it was possible to verify the effectiveness of radiation protection of the platelet when Alliin was injected to the blood vessel.

Protocol Optimization of Coronary CT Angiography (심혈관 CT 조영술의 프로토콜 최적화)

  • Lee, Hae-Kag;Yoo, Heung-Joon;Lee, Sun-Yeob;Goo, Eun-Hoe;Seok, Jong-Min;Han, Man-Seok;Lee, Kwang-Sung;Cho, Jae-Hwan;Kim, Bo-Hui;Park, Cheol-Soo
    • Journal of the Korean Society of Radiology
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    • v.5 no.2
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    • pp.51-58
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    • 2011
  • This research compared and analyzed the heart rate of the patient in which the LVEF value is 40% less than and normal patient. When as for LVEF 40% or less becomes to each heart rate and LVEF in a relation, we can know that the time to reach 100HU hangs long. Therefore, in patients, that is 40% less than, when setting up the Premonitoring delay, we could know to could give 5 primary solid phrases. It is seen that subsequently an addition injected 40cc as to Saline, to all patients by 4cc/sec speeds after injecting the capacity of Scan time ${\times}$ 4cc + 30cc with 4cc/sec speeds. And HR excludes 80 or greater in 40% less than, the contrast agent shows the large-scale difference. In addition, in 40% less than, it could predict that the time difference was big and the contrast agent was already out in the Left ventricle Wash- when the contrast agent reached 100HU and Scan was started There is a wide difference between under 40% LVEF and normal. when starting scan from low LVEF patients. So, Injection contrast media protocol Should be determined to CCTA. And then In case of low LVEF is recommended to more low Pitch than routine Pitch because we should reduce scan failed in accordance with low LVEF.

Phytoremediation of diesel-contaminated soils using alfalfa (Alfalfa를 이용한 디젤오염토양의 phytoremediation)

  • 심지현;이준규;심상규;황경엽;장윤영
    • Journal of Korea Soil Environment Society
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    • v.4 no.2
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    • pp.127-136
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    • 1999
  • In the past several years phytoremediation, defined as the use of plants for removing contaminants from media such as soils or water, has attracted a great deal of interest as a potentially useful remediation technology We attempted to assess the effectiveness of phytoremediation of diesel-contaminated soils in a green house. Screening test for selecting an appropriate plant was performed by observing the harmful effects of diesel dosage on the growth of 4 plants. Alfalfa was selected as a potentially useful plant among corn and barnyard grasses due to its high tolerance to the toxicity of diesel in growth. Bioremediation of the artificial diesel-contaminated soil packed in the PVC columns(0.3m in diameter $\times$ 1m in length) with air supplied, alfalfa planted, and alfalfa and air supplied was investigated for 100 days. The results of the column test showed plant effects on enhancing the biodegradation of diesel in the contaminated soils compared to the control column which had no plant. Injecting air to the columns during phytoremediation also showed additional effects on the removal rate of diesel. Comparison of microbial activity in each test column showed a beneficial effect of plants in the soil remediation processes. This results can be explained microbial activity in rhizosphere is a crucial factor for removing diesel.

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Improvement Method of Sand Ground Using an Environmental Friendly Bio-grouting Material (친환경 바이오그라우팅을 이용한 모래지반 개량 공법)

  • Kim, Dae-Hyeon;Sagong, Myung;Park, Kyung-Ho
    • Journal of the Korean Society for Railway
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    • v.16 no.6
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    • pp.473-481
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    • 2013
  • The purpose of this research is to evaluate the improvements in the strength and injection range of loose ground after injecting $CaCO_3$(created by microorganism reaction). For this purpose, three cases of single-layer (Sand, SP, SW) specimens were made in a 150mm D ${\times}$ 200mm H space and two cases of multi-layer specimens (SW/SP, SP/SW) were made in a 150mm D ${\times}$ 300mm H space. The specimens were made with a relative density of 30% of soft ground and an injection was given over a time of one day. The uniaxial compression strength was measured with a cone penetrometer and the injection range was observed by checking the bulb formation around the injection nozzle. Also, the compositions of the specimens were assessed through XRD analyses. Based on the test results, a compressive strength of 500kPa and 15cm thick cementation were noted due to the cementation of the soil. This implies that there are significant effects of the pore condition and size on bio-grouting technology.

A Role for the Carbohydrate Portion of Ginsenoside Rg3 in Na+ Channel Inhibition

  • Kim, Jong-Hoon;Hong, Yoon-Hee;Lee, Jun-Ho;Kim, Dong-Hyun;Nam, Ghilsoo;Jeong, Sang Min;Lee, Byung-Hwan;Lee, Sang-Mok;Nah, Seung-Yeol
    • Molecules and Cells
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    • v.19 no.1
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    • pp.137-142
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    • 2005
  • We showed recently that ginsenosides inhibit the activity of various types of ion channel. Here we have investigated the role of the carbohydrate component of ginsenoside $Rg_3$ in the inhibition of $Na^+$ channels. The channels were expressed in Xenopus oocytes by injecting cRNAs encoding rat brain Nav1.2 ${\alpha}$ and ${\beta}1$ subunits, and analyzed by the two-electrode voltage clamp technique. Treatment with $Rg_3$ reversibly inhibited the inward $Na^+$ peak current ($I_{Na}$) with an $IC_{50}$ of $32.2{\pm}4.5{\mu}M$, and the inhibition was voltage-dependent. To examine the role of the sugar moiety, we prepared a straight chain form of the second glucose and a conjugate of this glucose with 3-(4-hydroxyphenyl) propionic acid hydrazide (HPPH). Neither derivative inhibited $I_{Na}$. Treatment with the carbohydrate portion of ginsenoside $Rg_3$, sophorose [${\beta}-D-glucopyranosyl$ ($1{\rightarrow}2$)-${\beta}-glucopyranoside$], or the aglycone (protopanaxadiol), on their own or in combination had no effect on $I_{Na}$. These observations indicate that the carbohydrate portion of ginsenoside $Rg_3$ plays an important role in its effect on the $Na^+$ channel.

Generating Training Dataset of Machine Learning Model for Context-Awareness in a Health Status Notification Service (사용자 건강 상태알림 서비스의 상황인지를 위한 기계학습 모델의 학습 데이터 생성 방법)

  • Mun, Jong Hyeok;Choi, Jong Sun;Choi, Jae Young
    • KIPS Transactions on Software and Data Engineering
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    • v.9 no.1
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    • pp.25-32
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    • 2020
  • In the context-aware system, rule-based AI technology has been used in the abstraction process for getting context information. However, the rules are complicated by the diversification of user requirements for the service and also data usage is increased. Therefore, there are some technical limitations to maintain rule-based models and to process unstructured data. To overcome these limitations, many studies have applied machine learning techniques to Context-aware systems. In order to utilize this machine learning-based model in the context-aware system, a management process of periodically injecting training data is required. In the previous study on the machine learning based context awareness system, a series of management processes such as the generation and provision of learning data for operating several machine learning models were considered, but the method was limited to the applied system. In this paper, we propose a training data generating method of a machine learning model to extend the machine learning based context-aware system. The proposed method define the training data generating model that can reflect the requirements of the machine learning models and generate the training data for each machine learning model. In the experiment, the training data generating model is defined based on the training data generating schema of the cardiac status analysis model for older in health status notification service, and the training data is generated by applying the model defined in the real environment of the software. In addition, it shows the process of comparing the accuracy by learning the training data generated in the machine learning model, and applied to verify the validity of the generated learning data.

Characterization of an isolated reovirus from the paradise fish Macropodus opercularis imported from Southeast Asia (동남아시아로부터 수입된 paradise fish Macropodus opercularis로부터 분리한 reovirus의 특성)

  • Kim, Wi-Sik;Kim, Soo-Jin;Kim, Jeong-Ho;Jung, Sung-Ju;Kim, Do-Hyung;Oh, Myung-Joo
    • Journal of fish pathology
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    • v.23 no.3
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    • pp.335-342
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    • 2010
  • In 2008, mass mortality was observed in paradise fish Macropodus opercularis which was imported from Indonesia. PCR of these fish found positive for megalocytivirus and Mycobacterium sp., while an unidentified virus was culture-isolated using CHSE-214 cells. In the present study, we investigated characterization of the unidentified virus and its pathogenicity to determine whether the virus was the causative agent of the mass mortality of paradise fish. The unidentified virus induced cytopathic effect (CPE) with syncytia in CHSE-214 and other fish cells, BF-2, GF, SSN-1, FSP and FFN. The virus was resistant against treatments with IUdR, chloroform, acidity at pH 3, basicity at pH 11 and high temperature at $56^{\circ}C$ for 3h. By electron microscopy, the viral particles were spherical having a double capsid structure with approximately 65 nm in external diameter. Viral genome was composed of at least 10-segmented RNA with sizes ranging from 0.7 kb to 3.6 kb. Based on these characters, this virus can be classified into family Reoviridae. This reovirus did not cause any mortality in an artificial experiment conducted by injecting the virus to paradise fish. This indicates that the reovirus is not only responsible for the mass mortality of paradise fish in 2008.

Drainage system for leakage treatment of cement concrete structure in underground (콘크리트 지하구조물 누수 처리를 위한 유도배수시스템)

  • Kim, Dong-Gyou
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.21 no.4
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    • pp.573-585
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    • 2019
  • The objective of this study is to propose the drainage system that has been improved the workability, waterproofing and drainage performance to treat the leakage from the cement concrete structures in underground. It is improved that the pipe for conveying ground leak in the existing drainage system had the problem in workability and waterproof. The drainage systems with the improved pipe for conveying ground leak were constructed in conventional concrete lining tunnels to evaluate the workability, waterproofing and drainage. The waterproof and the drainage performance of the drainage system was evaluated by injecting 1,000 ml of red water in the back of the drainage system at 3 weeks, 6 weeks, 9 weeks, 11 weeks, 14 weeks, 17 weeks and 23 weeks. During 6 months of field performance test, the average daily temperature of the tunnel site was measured from $-12.4^{\circ}C$ to $19.7^{\circ}C$. The daily minimum temperature was $-17.2^{\circ}C$ and the daily maximum temperature was $26.7^{\circ}C$. There was no problem in waterproof and drainage performance on the pipe for conveying ground leak and the drainage system during 6 months for field performance test. It is concluded that the improved drainage system can be applied to various cement concrete underground structures where leakage occurs, and has little seasonal effect.

Long-term performance of drainage system for leakage treatment of tunnel operating in cold region (한랭지역에서 운영 중인 터널의 누수처리를 위한 유도배수시스템의 장기 성능 평가)

  • Kim, Dong-Gyou
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.20 no.6
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    • pp.1177-1192
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    • 2018
  • The objective of this study is to develop the existing drainage system for catching the partial leakage of tunnel structures operating in cold region. The drainage system consists of drainage board, Hotty-gel as a waterproofing material, cover for preventing protrusion of Hotty-gel, air nailer, fixed nail, pipe for collecting ground leak, pipe for conveying ground leak, wire-mesh, and sprayed cement mortar. The drainage systems were installed in conventional concrete lining tunnels to evaluate the site applicability and constructability. The performances of waterproof and the drainage in the drainage system were evaluated by injecting 1,000 ml of red water in the back of the drainage system at 7 days, 14 days, 21 days, 28 days, 2 months, 3 months, 4 months, 5 months, 6 months, 7 months and 8 months. During 8 months of field test, the average daily temperature of the tunnel site was measured from $-16.0^{\circ}C$ to $25.6^{\circ}C$. The daily minimum temperature was $-21.3^{\circ}C$ and the daily maximum temperature was $30.8^{\circ}C$. There was no problem in waterproof and drainage performance of the drainage board in the drainage system. However, the pipe for conveying ground leak had the leakage problem from 14 days. It is considered that the leakage of the pipe for conveying ground leak was caused by the deformation of the pipe of the flexible plastic material having a thickness of 0.2 cm by using the high pressure air nailer and the fixing pin and the insufficient thickness and width of the hotty-gel for preventing the leakage.

A Study on Stability according to the Conservation Environment for Fixative of Korean Mural Painting Layers (한국 흙벽화 채색층 고착제의 보존환경에 따른 안정성 연구)

  • Jin, Byung-hyuk;Wi, Koang-chul
    • Korean Journal of Heritage: History & Science
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    • v.46 no.3
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    • pp.150-171
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    • 2013
  • The most important part of conservation treatment of murals is to preserve them against the risk of a damage by injecting fixative into them when the painting loses its cohesion or powderization of pigments occurred due to occurrence of cracks inside the painting layer. However, studies on the stability of fixative used for painting layers of murals are still insufficient. This study manufactured a mural as a specimen and colored it with four kinds of pigments including oyster shell white, cinnabar, malachite and red clay and applied four kinds of fixative, including, Paraloid $B-72^{(R)}$, Caparol-$binder^{(R)}$, glue and Hydoxypropyl $cellulose^{(R)}$. artificially generated environmental changes in temperature, humidity and ultraviolet rays which may occur after the completion of conservation treatment. Then the changes in physical properties were observed in multifaceted ways such as color stability, contact angle, brilliance, adhesive strength and surface. As a result, this study found that ultraviolet rays and hot?humid environment have a large impact on color stability causing changes in brightness and chroma of all painting layers where the fixative were applied, except for oyster shell white and are considered the main factors of decomposition by accelerating the aging process of fixatives applied. In comparison to the synthetic resins that were also tested in this study, the traditional glue showed satisfactory results in terms of color stability and influence preservation and the hydrophile property. As it showed exceptionally outstanding adhesive strength in all painting layers in the aspect of adhesive strength, it is considered to be highly stabile for the fixation treatment of painting layers of mural.