• 전자공학회논문지SC
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• 제44권1호
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• pp.74-84
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• 2007

본 논문에서는 기존의 DLL 지연 시간 잠금 범위를 확장하기 위해 새로운 이중 루프 DLL을 제안하였다. 제안한 DLL은 Coarse_loop와 Fine_loop를 포함하고 있으며, 와부 클럭과 2개의 내부 클럭 사이의 초기 시간차를 비교하여 하나의 루프를 선택하여 동작하게 된다. 2개의 내부 클럭은 VCDL의 중간 출력 클럭과 최종 출력 클럭이며 두 클럭의 위상차는 $180^{\circ}$이다. 제안한 DLL은 일반적인 잠금 범위 밖에 있을 경우 Coarse_loop를 선택하여 잠금 범위 안으로 이전 시킨 후 Fine_loop에 의하여 잠금 상태가 일어난다. 따라서 제안한 DLL은 harmonic lock이 일어나지 않는 한 항상 안정적으로 잠금 과정이 일어날 수 있게 된다. 제안한 DLL이 사용하는 VCDL은 두 개의 제어 전압을 받아 지연 시간을 조절함으로 일반적인 다 적층 currentstarved 형태의 인버터 대신에 TG 트랜지스터를 이용하는 인버터를 사용하여 지연 셀을 구성하였다. 새로운 VCDL은 종래의 VCDL에 비하여 지연시간 범위가 더욱 확장되었으며, 따라서 제안한 DLL의 잠금 범위는 기존의 DLL의 잠금 범위보다 2배 이상 확장되었다. 본 논문에서 제안한 DLL 회로는 0.18um, 1.8V TSMC CMOS 라이브러리를 기본으로 하여 설계, 시뮬레이션 및 검증하였으며 동작 주파수 범위가 100MHz${\sim}$1GHz이다. 또한, 1GHz에서 제안한 DLL의 잠금 상태에서의 최대 위상 오차는 11.2ps로 높은 해상도를 가졌으며, 이때 소비 전력은 11.5mW로 측정되었다.

• 한국가스학회지
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• 제19권1호
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• pp.28-37
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• 2015

본 연구에서는 고속의 연산이 가능한 인공신경망 시뮬레이터와 SA 알고리즘을 결합하여 지능형 생산정 위치 최적화 전산 모델을 개발하였다. 기존의 사용하는 상용시뮬레이터의 경우 현장 규모의 저류 전산 시뮬레이션을 수행시 시간이 많이 소모되므로 이를 해결하기 위하여 이 모델에서는 인공신경망을 사용하여 짧은 시간내에 시뮬레이션을 수행할 수 있도록 하였다. 이렇게 얻은 결과를 주관적인 경험에 의거하지 않고 자동으로 최적의 생산정 위치를 선정할 수 있도록 최적화기법인 SA 알고리즘을 적용하였다. 개발된 모델을 사용하여 얻은 결과를 기존 사용 시뮬레이터와 비교하여 예측성능이 양호함을 검증할 수 있었으며, 연산속도 또한 향상됨을 확인하였다. 특히 SA 최적화 알고리즘의 제어변수인 초기온도와 냉각률에 대한 민감도분석을 실시하여 각각에 대한 최적값을 산출하였으며, 이를 통해 개발한 모델의 연산성능을 향상시킬 수 있었다. 마지막으로 개발된 모델을 사용하여 생산정 위치 최적화를 수행한 결과, 생산성이 우수한 지역을 선정하여 최적의 생산정 위치를 도출하였다.

• 한국지반환경공학회 논문집
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• 제10권5호
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• pp.19-26
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• 2009

짧은 쇄석다짐말뚝 공법(RAP)은 깊은 기초와 얕은 기초의 중간개념으로 1989년 미국에서 시작하여 세계적으로 활용성을 넓혀가고 있다. 국내의 경우, 체계적인 조사 및 연구가 이루어지지 않아 실제 현장에 적용하기 위한 설계시방이나 지지력 산정방법 등의 확보가 시급한 실정이다. 본 연구는 RAP공법의 구조물 기초로서의 배치형태에 따른 지지력 측정을 통해 사용성 확보를 위한 기초연구로써, 지지력 측면에서 최적의 배치에 대한 적용방안을 검증하기 위해서 이루어졌다. RAP공법이 적용된 지반의 지지력을 실내모형토조시험을 통하여 검토하였다. 연구방법은 사질토로 조성된 모형지반에 RAP의 배치형태별(정방형, 육각형, 십자형, 마름모형), 직경별(20mm, 30mm, 40mm)로 변위제어시험을 수행하여 RAP의 지지력을 검토하였다. 실험결과, 중심간 간격이 좁아짐에 따라 인접한 말뚝에 의한 구속효과 및 변형억제 등의 상호작용 효과가 증대되어 지지력이 증가하였으며, 직경이 커질수록 강성이 커져서 지지력이 증가하였다. 또한, 말뚝의 중심간격이 좁아짐에 따라 주변지반이 조밀해지면서 침하량도 감소하였다. 향후 다양한 현장계측자료의 축적을 통한 지속적인 검증작업과 침하량 및 지지력 측면에서 RAP의 최적 배치형태에 대한 연구가 요망된다.

• Journal of Yeungnam Medical Science
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• 제8권2호
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• pp.35-44
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• 1991

저자들은 1990년 3월부터 1991년 2월까지 영남대학교 의과대학 부속병원 신경외과학교실에서 뇌정위적 수술을 시행하여 뇌실질내 출혈부위와 뇌실내에 모두 도관을 삽입한 자발성 뇌실질내 출혈 환자 30례에서 뇌압변화와 임상증상의 변화를 분석하였다. 자발성 뇌실질내 출혈은 40-60대에 주로 발생하였고, 여자가 2.3배로 많았으며, 출혈위치는 피각부, 시상부, 소뇌부 등의 순으로 많았다. 그리고 고혈압의 기왕력을 가진 사람이 많았으며, 고혈압과 연관된 심전도 소견을 보인 경우가 많았다. 평균 동맥혈 이산화탄소분압이 높은 환자에서 뇌압이 높았으며, 뇌압과 재출혈 및 퇴원시 ADL과는 유의한 관계는 없었다. 수술후 72시간경에 뇌압이 가장 높았으며, 뇌실질내 출혈 부위에 6000 IU 유로키나제 세척을 시행한 결과 유로키나제 세척후는 전에 비하여 평균 63.2%의 감압이 있었다. 뇌압이 높은 경우 Natural drainage를 많이 시행 했으나, Natural drainage 횟수와 퇴원시 ADL과는 유의한 상관 관계를 보이지 않았다. 처음 GCS이 높을수록 수술후에 GCS이 높았으며, 평균 뇌압이 높을수록 평균 GCS이 낮아 환자 상태가 나쁜 경우가 많았다.

• Asian-Australasian Journal of Animal Sciences
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• 제11권6호
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• pp.692-696
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• 1998

An experiment was conducted with eight growing sheep (average initial weight 20.6 kg and average final weight 23.7 kg) in a $4{\times}4$ Latin square design to study the effect of type of forage supplementation to a basal diet of rice straw (ad libitum) and cassava (Manihot esculanta, approximately 9 g of dry matter $(DM).kg^{-0.75}{\cdot}day^{-1}$) on voluntary intake, digestion, rumen microbial protein synthesis and daily weight gain. Forages used were Leucaena (L, Leucaena leucocephala), Gliricidia (G, Gliricidia maculata) and Tithonia (T, Tithonia diversifolia, wild sunflower) at a DM supplementation level of approximately $13g.kg^{-0.75}.day^{-1}$. Organic matter intake was 40.4, 55.5, 55.0 and $54.9g{\cdot}kg.^{-0.75}{\cdot}day^{-1}$ for control (C, ad libitum straw and cassava), L, G and T. respectively, significantly lower for C than for the supplemented diets. Intake of supplementary forage had also a significantly positive effect on voluntary rice straw intake. All forage supplemented diets showed a significantly higher whole diet organic matter digestion than C ($488g{\cdot}kg^{-1}$), while T ($557g{\cdot}kg^{-1}$) differed significantly from L ($516g{\cdot}kg^{-1}$) but not from G ($526g{\cdot}kg^{-1}$). Daily weight gain was -1.7, 5.2, 5.4 and $4.7g{\cdot}kg^{-0.75}$, for C, L, G and T. respectively, significantly lower for C than for the forage-supplemented diets. Efficiency of microbial protein synthesis estimated from urinary excretion of purine derivatives was lower for C (3.8 g microbial N. (kg digestible organic matter intake $(DOMI))^{-1}$ than for the forage supplemented diets (11.3, 9.0 and 9.4 g microbial $N.(kg\;DOMI)^{-1}$ for L, G and T. respectively).

• Asian-Australasian Journal of Animal Sciences
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• 제23권10호
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• pp.1308-1318
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• 2010

The purpose of this study was to evaluate the effect of replacing soybean meal with treated castor meal with (CMT) or without lime (CMNT) on the nutrient intake, performance, carcass characteristics, and yield of commercial cuts of beef cattle from a feedlot. Thirty male, castrated, crossbreed zebu cattle were used in the study, with an average initial weight of $360{\pm}30.27\;kg$. Five animals were used as a control group and were slaughtered at the beginning of the experiment; the remaining animals (n = 25) were distributed in random blocks (repetitions), with body weight as the criterion for block assignment. The animals were fed a diet containing 65% corn silage and 35% of concentrate on dry matter (DM) basis. Five diets consisted of four levels of soybean meal (SM) substituted with CMT (0, 33, 67 and 100%) on a DM basis and a diet with 100% of SM replaced with CMNT. At the end of the experiment, all animals were slaughtered, and their gastrointestinal tracts were emptied to determine their empty body weights (EBW). No significant effects were observed (p>0.05) for the substitution of soybean meal with CMT on intake of dietary nutrients, the average daily body weight gain (ADG) or EBW gain (EBWG). In spite of greater (p<0.05) ricin intake for the diet containing CMNT (3.06 mg/kg BW) compared to the CMT diet (0.10 mg/kg BW/d), there were no effects (p>0.05) on intake of dietary nutrients, ADG or EBWG. The average intake of DM and the ADG were 10,664.63 and 1,353.04 g/d, respectively. Regarding carcass characteristics, only carcass yield in relation to body weight was linearly reduced (p<0.05) upon substitution of SM by CMT. There was no effect (p>0.05) of the substitution of SM by CMT or CMNT on the yield of carcass basic cuts. CMT prices that are higher than 85% of the SM price do not economically justify the use of CMT. For CMT prices between 20 and 80% of the SM price, the optimal level was 67% substitution, while for prices below 15% of the SM price, the optimal level was 100% substitution with CMT. It can be concluded that treated castor meal with 6% lime can totally replace soybean meal in beef cattle diets.

• Asian-Australasian Journal of Animal Sciences
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• 제26권6호
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• pp.820-826
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• 2013

The objective of this study was to determine the effect of rain tree pod meal with palm oil supplementation on feed intake, digestibility, microbial protein synthesis and microbial populations in dairy cows. Four, multiparous early-lactation Holstein-Friesian crossbred (75%) lactating dairy cows with an initial body weight (BW) of $405{\pm}40$ kg and $36{\pm}8$ DIM were randomly assigned to receive dietary treatments according to a $4{\times}4$ Latin square design. The four dietary treatments were un-supplementation (control), supplementation with rain tree pod meal (RPM) at 60 g/kg, supplementation with palm oil (PO) at 20 g/kg, and supplementation with RPM at 60 g/kg and PO at 20 g/kg (RPO), of total dry matter intake. The cows were offered concentrates, at a ratio of concentrate to milk production of 1:2, and chopped 30 g/kg of urea treated rice straw was fed ad libitum. The RPM contained condensed tannins and crude saponins at 88 and 141 g/kg of DM, respectively. It was found that supplementation with RPM and/or PO to dairy cows diets did not show negative effects on feed intake and ruminal pH and BUN at any times of sampling (p>0.05). However, RPM supplementation resulted in lower crude protein digestibility, $NH_3$-N concentration and number of proteolytic bacteria. It resulted in greater allantoin absorption and microbial crude protein (p<0.05). In addition, dairy cows showed a higher efficiency of microbial N supply (EMNS) in both RPM and RPO treatments. Moreover, NDF digestibility and cellulolytic bacteria numbers were highest in RPO supplementation (p<0.05) while, supplementation with RPM and/or PO decreased the protozoa population in dairy cows. Based on this study, supplementation with RPM and/or PO in diets could improve fiber digestibility, microbial protein synthesis in terms of quantity and efficiency and microbial populations in dairy cows.

• Asian Pacific Journal of Cancer Prevention
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• 제17권1호
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• pp.419-424
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• 2016

Background: The aim of this systematic review was to study the relationship between exposure to nitrogen dioxide ($NO_2$) in the ambient air and breast cancer incidence. Materials and Methods: A systematic review was performed based on the MOOSE guideline for review of observational studies. We searched five online databases (PubMed, Science Direct, Google Scholar, EBSCO, and Scopus) from their conception to June 2014. A pooled estimate of the correlation between $NO_2$ exposure and breast cancer incidence was calculated using Pearson's correlation coefficient. Results: A total of 654 titles were retrieved in the initial search of the databases. Further refinement and screening of the retrieved studies produced a total of five studies from four countries. The studies included three ecological studies (aggregate level) and two individual based studies (one prospective cohort and the other one a case-control study). The ecological studies were pooled and the meta-analysis of correlation coefficient without z transformation showed a pooled estimate of r = 0.89 with 95% CI of 0.84 to 0.95. Using z transformation, the pooled r was 1.38 with 95%CI of 1.11 to 1.59. No significant heterogeneity between studies was observed. Following a sensitivity analysis and the removal of each study from pooled analysis we did not see any significant change in the pooled estimate. Conclusions: It was concluded that there is a tendency toward a weak association between exposure to $NO_2$ in ambient air and breast cancer at the individual level and a significant association at the aggregate level.

• Asian Pacific Journal of Cancer Prevention
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• 제16권14호
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• pp.6033-6038
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• 2015

Background: Experience of lung cancer includes negative impacts on both physical and psychological health. Pain is one of the negative experiences of lung cancer. Cognitive behavioral therapy techniques are often recommended as treatments for lung cancer pain. The objective of this review was to synthesize the evidence on the effectiveness of cognitive behavioral therapy techniques in treating lung cancer pain. This review considered studies that included lung cancer patients who were required to 1) be at least 18 years old; 2) speak and read English or Thai; 3) have a life expectancy of at least two months; 4) experience daily cancer pain requiring an opioid medication; 5) have a positive response to opioid medication; 6) have "average or usual" pain between 4 and 7 on a scale of 0-10 for the day before the clinic visit or for a typical day; and 7) able to participate in a pain evaluation and treatment program. This review considered studies to examine interventions for use in treatment of pain in lung cancer patients, including: biofeedback, cognitive/attentional distraction, imagery, hypnosis, and meditation. Any randomized controlled trials (RCTs) that examined cognitive behavioral therapy techniques for pain specifically in lung cancer patients were included. In the absence of RCTs, quasi-experimental designs were reviewed for possible conclusion in a narrative summary. Outcome measures were pain intensity before and after cognitive behavioural therapy techniques. The search strategy aimed to find both published and unpublished literature. A three-step search was utilised by using identified keywords and text term. An initial limited search of MEDLINE and CINAHL was undertaken followed by analysis of the text words contained in the title and abstract, and of the index terms used to describe the article. A second search using all the identified keywords and index terms was then undertaken across all included databases. Thirdly, the reference list of all identified reports and articles were searched for additional studies. Searches were conducted during January 1991- March 2014 limited to English and Thai languages with no date restriction. Materials and Methods: All studies that met the inclusion criteria were assessed for methodological quality by three reviewers using a standardized critical appraisal tool from the Joanna Briggs Institute (JBI). Three reviewers extracted data independently, using a standardized data extraction tool from the Joanna Briggs Institute (JBI). Ideally for quantitative data meta-analysis was to be conducted where all results were subject to double data entry. Odds ratios (for categorical data) and weighted mean differences (for continuous data) and their 95% confidence intervals were to be calculated for analysis and heterogeneity was to be assessed using the standard Chi-square. Where statistical pooling was not possible the finding were be presented in narrative form. Results: There were no studies located that met the inclusion requirements of this review. There were also no text and opinion pieces that were specific to cognitive behavioral therapy techniques pain and lung cancer patients.Conclusions: There is currently no evidence available to determine the effectiveness of cognitive behavioural therapy techniques for pain in lung cancer patients.

• Asian-Australasian Journal of Animal Sciences
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• 제33권12호
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• pp.1985-1990
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• 2020

Objective: The objective of this experiment was to investigate the effects of fat-soluble vitamin injection on plasma and tissue vitamin status in nursery pigs. Methods: A total of 16 pigs (initial body weight: 7.15±1.1 kg) were allotted to 2 treatments at d 7 post-weaning. Pigs were fed a corn-soybean meal-based basal diet with no supplemental vitamin A and i.m. injected with 300,000 IU of retinyl palmitate, 900 IU of d-α-tocopherol and 30,000 IU of vitamin D₃ with control pigs having no vitamin injection. Blood (d 0, 3, 7, and 14 post-injection) and tissue samples (liver, brain, heart, lung, and muscle; d 7 and 14 post-injection) were collected from pigs. Retinyl palmitate, retinol, and α-tocopherol concentrations were analyzed in plasma and tissues, while plasma was assayed for 25-hydroxycholecalciferol (25-OHD₃). Results: Plasma retinol and 25-OHD₃ concentrations increased by the vitamin injection from d 3 to 14 post-injection (p<0.05) whereas plasma retinyl palmitate was detected only in the vitamin treatment at d 3 and 7 post-injection (115.51 and 4.97 ㎍/mL, respectively). Liver retinol, retinyl palmitate, and retinol+retinyl palmitate concentrations increased by retinyl palmitate injection at d 7 and 14 post-injection (p<0.05) whereas those were not detected in the other tissues. The d-α-tocopherol injection increased α-tocopherol concentrations in plasma at d 3 and 7 post-injection (p<0.05) and in liver, heart (p<0.10), and muscle (p<0.05) at d 7 post-injection. Conclusion: Fat-soluble vitamin injection increased plasma status of α-tocopherol, retinol, retinyl palmitate and 25-OHD₃. As plasma levels decreased post-injection, vitamin A level in liver and vitamin E level in muscle, heart and liver increased. The α-tocopherol found in plasma after injection was distributed to various tissues but retinyl palmitate only to the liver.