• Clinical and Experimental Pediatrics
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• 제59권11호
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• pp.432-439
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• 2016

Asthma is recognized as a complex disease resulting from interactions between multiple genetic and environmental factors. Accumulating evidence suggests that respiratory viral infections in early life constitute a major environmental risk factor for the development of childhood asthma. Respiratory viral infections have also been recognized as the most common cause of asthma exacerbation. The advent of molecular diagnostics to detect respiratory viruses has provided new insights into the role of human rhinovirus (HRV) infections in the pathogenesis of asthma. However, it is still unclear whether HRV infections cause asthma or if wheezing with HRV infection is simply a predictor of childhood asthma. Recent clinical and experimental studies have identified plausible pathways by which HRV infection could cause asthma, particularly in a susceptible host, and exacerbate disease. Airway epithelial cells, the primary site of infection and replication of HRV, play a key role in these processes. Details regarding the role of genetic factors, including ORMDL3, are beginning to emerge. This review discusses recent clinical and experimental evidence for the role of HRV infection in the development and exacerbation of childhood asthma and the potential underlying mechanisms that have been proposed.

• 한국응용과학기술학회지
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• 제41권2호
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• pp.188-198
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• 2024

본 연구는 코로나19 대유행을 경험한 대학생의 호흡기감염 예방 이행 수준과 영향요인을 파악하고자 시행하였다. 2023년 12월 15일부터 2024년 1월 5일까지 대학생 200명을 대상으로 온라인 설문조사를 시행하였으며, 이 중 성실히 응답한 199명의 자료를 SPSS 18.0 program을 이용하여 기술통계량, t-test, ANOVA, multiple regression으로 분석하였다. 연구결과 호흡기감염 예방 이행 수준은 48점 만점 중 평균 32.95±6.05점이었다. 호흡기감염 예방 이행 수준에 차이를 보인 일반적 특성과 호흡기감염 관련 특성은 학과(t=-2.59, p=.010), 호흡기감염 예방 교육(t=1.99, p=.048), 금년 독감예방접종(t=-2.10, p=.037), 금년 코로나19 예방접종(t=3.56, p<.001), 외출 시 사람이 모여 있는 곳에서 마스크 착용(t=4.96, p<.001)이었다. 호흡기감염 예방 이행에 영향을 미치는 요인으로 학과(β=0.31, p<.001), 금년 독감예방접종(β=-0.15, p=.046), 외출 시 사람이 모여 있는 곳에서 마스크 착용(β=-0.31, p<.001)이 다중회귀분석에서 유의한 변수로 확인되었다. 결론적으로 코로나19 유행이 종식된 이후에도 호흡기감염이 지속적으로 발생하므로 호흡기감염 예방행위 이행 증진을 위한 노력이 필요하며, 대학생을 대상으로 한 호흡기감염 예방 프로그램 개발 시 본 연구에서 확인된 요인들을 기초자료로 활용할 수 있을 것으로 기대한다.

• 한국식물병리학회지
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• 제10권2호
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• pp.78-82
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• 1994

Unusually severe rice blast epidemic sweeped over the rice growing area in Gyeongnam Province and elsewhere in 1993. Leaf blast infection was reached to 33,133 ha, which is about 24.5% of total paddy area and neck blast infection was apparent throughout 4,421 ha. Major factors affecting such an unusual epidemic appeared to be as follow: Firstly, low temperature, frequent rainfall and coincidentally insufficient duration of sunshine through July and August; Secondly, most cultivars possessing low levels of field resistance were cultivated in wide areas: Thirdly, blast fungus population was enough for successive infection under optimum weather condition and most races distributed in field were able to infect most cultivars.

• 한국치위생학회지
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• 제15권3호
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• pp.363-369
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• 2015

Objectives: The purpose of this study is to investigate the cognition and practice of infection control in the dental hygienists. Methods: A self-reported questionnaire was completed by 220 dental hygienists in Busan and Gyeongnam from August 1 to 31, 2014. The questionnaire was adapted from Nam. The questionnaire consisted of four questions of the general characteristics of the subjects, two questions of infection control factors, four questions of clinic environment, 50 questions of awareness of infection control, and 50 questions of infection control practice. Cronbach's alpha in the awareness of infection control was 0.958 and that in infection control practice was 0.950. Results: The dental hygienists in the large scale hospitals tended to have higher score of cognition and practice of infection control thatn those in the small scale hospitals(p<0.001). Small scale hospitals tended to have lower infection rate than the large scale hospitals. The education for the infection control guideline reduced the infection prevalence rate. Conclusions: In order to reduce the infection prevalence rate, it is necessary to educate the dental hygienists continuously and to provide the infection control guideline to the dental clinics.

• Parasites, Hosts and Diseases
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• 제52권4호
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• pp.391-397
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• 2014

We evaluated the status of Clonorchis sinensis infection and potential risk factors among residents of riverside areas (Geumgang) in Muju-gun, Jeollabuk-do (Province), Korea. From January to February 2010, a total of 349 (171 males, 178 females) stool samples were collected and examined by the formalin-ether concentration technique. Also, village residents were interviewed using questionnaires to obtain information about C. sinensis infection-related risk factors. Overall egg-positive rate of C. sinensis was 13.2%. Egg-positive rates were significantly higher in males, farmers, and residents who had lived there more than 20 years, and in residents who had eaten raw freshwater fish than in opposite groups, respectively. However, there was no significant difference between age groups, education levels, cigarette smoking, alcohol drinking, health status, past history of infection, and experience of clonorchiasis medication and examination. Logistic regression analysis was performed to determine risk factors for clonorchiasis. On univariate analysis, the odds ratios for males, farmers, those who had lived there more than 20 years, and who had eaten raw freshwater fish were 2.41, 4.44, 3.16, and 4.88 times higher than those of the opposites, respectively. On multivariate analysis, the odds ratio of residents who had eaten raw freshwater fish was 3.2-fold higher than that of those who had not. These results indicate that residents living in Muju-gun, along the Geum River, Korea, have relatively high C. sinensis egg-positive rates, and the habit of eating raw freshwater fish was the major factor for the maintenance of clonorchiasis.

• 대한수의학회지
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• 제39권6호
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• pp.1126-1140
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• 1999

Renal failure is one of the main causes of economic impacts in the poultry industry and complex syndrome with different severity of clinical signs caused by multiple nephropathogenic factors such as infectious bronchitis viral infection and excess salt and calcium in diet. To evaluate the correlation between severity of renal failure and the causative nephropathogenic factors, one-day-old specific pathogen free chicks were treated with either single causative factor or multiple causative factors described as above. Each group was designed as control for non-treated control, IB for infectious bronchitis virus (IB virus) infection, IBHNa for IB virus infection with high diet salt, IBHCa for IB virus infection with high diet calcium, IBHNC for IB virus infection with high diet salt and calcium, HNa for high diet salt, HCa for high diet calcium and HNC for high diet salt and calcium. Chickens were inoculated with IB virus at 1-day-old and remained on their respective diets until 21 day of age. The high dietary salt feeding groups such as IBHNa, IBHNC, HNa, HNC increased water intake, watery diarrhea, general subcutaneous edema and the high dietary calcium feeding groups such as IBHCa and IBHNC showed severe visceral gout. Two more than treated groups caused high mortality in comparison with the single treated groups. IB virus exposure significantly increased urate deposition and lymphocytic interstitial nephritis. Especially urate deposition dramatically increased when excess diet calcium was combined together. In excess diet salt treated groups enlarged edematous kidneys were observed and hypertrophy of glomeruli were showed. These results suggest that IB virus enhanced the incidence and severity on chicken renal failure clearly related to the quantity of salt and calcium.

• 대한수의학회지
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• 제39권6호
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• pp.1141-1150
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• 1999

Renal failure is one of the main causes of economic impacts in the poultry industry and complex syndrome with different severity of clinical signs caused by multiple nephropathogenic factors such as infectious bronchitis viral infection and excess salt and calcium in diet. To evaluate the correlation between severity of renal failure and the causative nephropathogenic factors, one-day-old specific pathogen free chickens were treated with either single causative factor or multiple causative factors described as above. Each group was designed as control for non-treated control, IB for infectious bronchitis virus (IB virus) infection, IBHNa for IB virus infection with high diet salt, IBHCa for IB virus infection with high diet calcium, IBHNC for IB virus infection with high diet salt and calcium, HNa for high diet salt, HCa for high diet calcium and HNC for high diet salt and calcium. Chickens were inoculated with IB virus at 1-day-old and remained on their respective diets until 21 day of age. Plasma $Na^+$, $Cl^-$, BUN, creatinine, calcium and uric acid values were examined. The results obtained were as follows ; IB virus and high dietary calcium combined treatment showed elevated plasma uric acid. BUN and creatinine values were not characteristic on chicken renal failure. But plasma uric acid values were increased according to renal lesion. Hypercalcemia and hyperuricemia did not induce urate deposition and mineralization in the kidney.

• 임상간호연구
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• 제27권1호
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• pp.45-53
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• 2021

Purpose: This study was conducted to assess the factors affecting turnover intention of the nurses working in neonatal intensive care units, including the extent of fatigue, work stresses, and work overload related to infection control. Methods: This was a descriptive correlational study to test factors affecting the turnover intention of the nurses working in neonatal intensive care units. Data was analyzed utilizing descriptive statistics, t-test, One-way ANOVA, Pearsons' Correlation Coefficient, and multiple regressions by using the IBM SPSS Statistics 23.0 Program(IBM Corp., Armonk, NY). Results: The turnover intention of nurses had a positive correlation with the extent of fatigue (r=.54, p<.001), work stress (r=.40, p<.001), and with the work overload (r=.43, p<.001) related to infection control. In addition, factors affecting the turnover intention of nurses included the extent of fatigue (β=.52, p<.001) related to infection control and the number of pediatric patients assigned to each nurse (β=.26, p=.001) and the variances explained by the regression model was 37.0%. Conclusion: It is necessary to establish and implement strategies to lower the extent of fatigue related to infection control by reducing the nurses' workload. Securing additional nurses to ensure an appropriate number of pediatric patients assigned to each nurse, and providing efficient management and available resources to reduce the turnover intention of nurses working in neonatal intensive care units are suggested.

• 산업융합연구
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• 제21권3호
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• pp.129-138
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• 2023

본 연구는 코로나19 감염 경험 여부에 따른 여성암 생존자의 건강관련 삶의 질에 영향을 미치는 요인을 파악하고자 시도되었다. 연구는 여성암 생존자 137명을 대상으로 2022년 11월 1일부터 2023년 1월 24일 까지 자료를 수집하였으며, 자료 분석은 SPSS 25.0 program을 이용하여 기술통계, 독립표본 t검정, 상관분석 및 다중회귀분석을 실시하였다. 건강관련 삶의 질에 영향을 미치는 요인을 확인한 결과 코로나19에 감염경험이 있는 군은 나이(𝛽=.20, p<.05), 우울(𝛽=-.29, p<.01), 불안(𝛽=-.39, p<.001)과 사회적 지지(𝛽=.35, p<.001)가 유의한 영향요인으로 확인되었다(F=26.932, p<.001). 반면 코로나 19 감염경험이 없는 군에서는 나이(𝛽=.22, p<.001), 불안(𝛽=-.54, p<.001)과 코로나19 예방행위(𝛽=.25, p<.001)가 유의한 것으로 드러났다(F=64.937, p<.001). 코로나19 고위험군인 여성암 생존자의 건강관련 삶의 질을 향상시키기 위해 관련요인을 고려한 맞춤형 접근이 필요하다.

• Asian-Australasian Journal of Animal Sciences
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• 제29권4호
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• pp.580-585
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• 2016

The objective of this study was to determine cow characteristics and farm management factors during the dry period associated with early postparturient intramammary infection (IMI) and subsequent clinical mastitis (CM). Data were collected three times: before drying off (P1), during the dry period (P2), and 5 to 14 days after calving (P3), using questionnaires and farm investigation. Milk samples were aseptically collected for bacterial identification at P1 and P3. Factors associated with IMI and CM were analyzed using multiple logistic regression models. The final model showed that IMI in early postpartum was significantly associated with full insertion of dry cow antibiotic, dry cows in barns with a combination of tie and free stalls, body condition score (BCS) in dry period and after calving, and milk yield before drying off. For IMI cows, factors significantly associated with clinical expression of mastitis were having daily barn cleaning, teat disinfected with alcohol before administration of dry cow therapy, BCS before drying off, milk yield before drying off, and days in milk at drying off. In conclusion, both cow and farm management factors are associated with the IMI rate and subsequent expression of clinical signs of mastitis in early postpartum cows.