• Restorative Dentistry and Endodontics
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• 제40권1호
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• pp.79-84
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• 2015

This case report presents surgical endodontic management outcomes of maxillary incisors that were infected via the lateral canals. Two cases are presented in which endodontically-treated maxillary central incisors had sustained lateral canal infections. A surgical endodontic treatment was performed on both teeth. Flap elevation revealed vertical bone destruction along the root surface and infected lateral canals, and microscopy revealed that the lateral canals were the origin of the lesions. After the infected lateral canals were surgically managed, both teeth were asymptomatic and labial fistulas were resolved. There were no clinical or radiographic signs of surgical endodontic management failure at follow-up visits. This case report highlights the clinical significance and surgical endodontic management of infected lateral canal of maxillary incisor. It is important to be aware of root canal anatomy variability in maxillary incisors. Maxillary central incisors infected via the lateral canal can be successfully managed by surgical endodontic treatment.

• 한국보건간호학회지
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• 제37권1호
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• pp.136-146
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• 2023

This cross-sectional design study was undertaken to determine the factors associated with suicidal ideation in human immunodeficiency virus (HIV)-infected older adults. Data from a city-wide representative sample collected by the Seoul Metropolitan Government were used. The cross-sectional survey was conducted between February and March 2013. Participants selected and included in the analysis were HIV-infected adults living in Seoul, and aged 50 years and older. The overall adjusted model showed that being unemployed (adjusted odds ratio [aOR], 3.34; 95% confidence interval [CI], 1.16-9.57), a history of depression treatment (aOR, 4.61; 95% CI, 1.02-20.66), perceived belongingness (aOR, 0.63; 95% CI, 0.41-0.99), and psychological functioning (aOR, 0.85; 95% CI, 0.73-0.99) were significantly related to suicidal ideation. Psychosocial features were found to be strongly associated with suicidal ideation among HIV-infected older adults. The findings could be useful for HIV nursing consultants to identify HIV-infected older adults who are vulnerable to suicidal ideation. Comprehensive mental health services should be provided as coping resources for HIV-infected older adults who have suicidal ideation.

• 보건교육건강증진학회지
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• 제19권2호
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• pp.115-125
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• 2002

This study is a investigation research to examine total 123 children's thought, perception and coping method about measles, with 62 children who had experienced the measles and 61 good health children in the school, which had spread to a primary school in kyoungsang-bukdo province. The data collection was done from December 6 to December 8. The analysis of data was SPSS(10.0) for descriptive statistics. The data were collected from total 123 children, 62 of them who had diagnosed measles on October, 2000, when the measles had ended, were used a purposive sampling, the others who had a good health were used a convenience sampling. From three to six grade students made out directly the questionaire in the way of self-questionaire, and from one to two grade students, made out answering the question which the researcher had read the items. The researchers call back the students to complement the contents about the items inadequate answers, so they raised the reliability. The results were as follows. 1. The results of observe carefully the measles infection degree by a sex, the boys(27.4%) were sick severely compared with girls(9.7%)were sick weakly compared with the boys(27.4%)(p〈0.01). 2. The 62.9 percents of infected children by measles thought that they were infected at school, regarded the doctors as a first judge, and had caught the measles because of their fault. The results of observe carefully, 33.8 percents children of infected by measles had have a secondary vaccination. To the question whether they go to institute or not while suffering from the measles, 35.5% children didn't go there since they had heard the fact they infected the measles. 3. To a question of asking if close mend caught the measles, what will they do, 65.1% children of caught the measles answer ‘I can't meet my friend'(p〈0.001). It was significant that infected children have more interests than didn't infected children. The 22% children of didn't catch the measles take great interested in health compare with the 12.2% children of infected the measles(p〈0.05). To the question if they listen the preservation of health broadcasting, 63.4% children answer ‘I listen well’. It was significant between the infected group and didn't infect group(p〈0.05). To the question if they delivery to the written information at home, it was significant between the infected group and didn't infect group(p〈0.05). 4. The infected group of 69.1% children think the health is most important in their life school than any other they like study.

• 문화기술의 융합
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• 제7권2호
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• pp.443-451
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• 2021

이 연구는 재선충 감염 소나무와 비 감염 소나무의 수분함유율에 따른 연소열 실험을 통해 열적특성을 비교 분석하였다. 실험 결과는 다음과 같다. 수분 함유율 분석 결과는 재선충 감염 소나무의 경우 평균 19.92%, 비 감염 소나무는 26.27%로 화재 시 전도, 대류, 복사열 크기가 커질수록 수분 함유량이 감소한다. 수분 함유량의 기화가 가속되면 평형 수분 함유율에 도달하고 수분 함유율이 15%이하에서는 열원에 의하여 착화되지 않는다는 목재의 열적 특성에 상반되는 결과이다. 연소열 분석 결과는 재선충 감염 소나무와 비 감염 소나무는 연소열은 약 3%로 큰 차이를 보이지 않았다. 하지만 연소열이 다른 수종에 비해서는 높은 수치를 나타낸다는 것을 알 수 있다. 결론적으로 전도, 대류, 복사열의 증가에 따른 수분 함유율의 감소가 착화에 직접적인 원인 중 하나이며 수분 함유량이 감소할 수록 화재 확산 속도도 빨라진다는 것을 알 수 있었다.

• Parasites, Hosts and Diseases
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• 제42권4호
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• pp.175-183
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• 2004

To evaluate the role of nitric oxide (NO) in $IFN-{\gamma}$ production and apoptosis of splenocytes in genetically different strains of mice with toxoplasmosis, BALB/c (a toxoplasmosis resistant strain) and C57BL/6 (a toxoplasmosis susceptible strain) mice were infected with Toxoplasma gondii cysts orally and subsequently injected intraperitoneally with aminoguanidine, an iNOS inhibitor (AG; 35 mg/kg per mouse daily for 14 days). When BALB/c or C57BL/6 mice were infected with T. gondii without AG treatment, number of brain cysts, NO and IFN-y production by splenocytes, and percentages of apoptotic splenocytes were increased compared to uninfected control mice without AG treatment. AG treatment increased the number of brain cysts, and reduced NO and $IFN-{\gamma}$ production in T. gondii-infected C57BL/6 mice. In contrast, in T. gondii-infected BABL/c mice, the number of brain cysts, and NO and $IFN-{\gamma}$ production of splenocytes was not altered by treatment with AG. However, the percentages of apoptotic splenocytes in T. gondii-infected BALB/c or C57BL/6 mice were not affected by AG treatment. These results suggest that NO modulates $IFN-{\gamma}$ production in T. gondii-infected C57BL/6 mice, and that NO is involved in mediating a protective response in toxoplasmosis susceptible, but not resistant, mice strain during acute infection.

• Asian Pacific Journal of Cancer Prevention
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• 제17권10호
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• pp.4643-4646
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• 2016

The CC chemokine receptor 5 (CCR5) delta 32 allele results in a nonfunctional form of the chemokine receptor and has been implicated in a variety of immune-mediated diseases. $CCR5{\Delta}32$ may also predispose one to chronic liver disease or be linked with resistance to HBV infection. This study was undertaken to investigate any association between CCR5 polymorphism with resistance to hepatitis B or susceptibility to HBV infection. A total of 812 Iranian individuals were enrolled into two groups: HBV infected cases (n=357), who were HBsAg-positive, and healthy controls (n=455). We assessed polymorphisms in the CCR5 gene using specific CCR5 oligonucleotide primers surrounding the breakpoint deletion. Genotype distributions of the HBV infected cases and healthy controls were determined and compared. The CCR5/CCR5 (WW) and $CCR5/CCR5{\Delta}32$ (W/D) genotypes were found in (98%) and (2%) of HBV infected cases, respectively. The $CCR5{\Delta}32/{\Delta}32$genotype was not found in HBV infected cases. Genotype distributions of CCR5 in healthy controls were W/W genotype in (87.3%), W/D genotype in (11.2%) and D/D genotype in (1.5%). Heterozygosity for $CCR5/CCR5{\Delta}32$ (W/D) in healthy controls was greater than in HBV infected cases (11.2% vs 2%, p < 0.001). W/D and D/D genotypes were more prominent in healthy controls than in HBV infected cases. This study provides evidence that the $CCR5{\Delta}32$ polymorphism may have a protective effect in resistance to HBV infection at least in the Iranian population.

• 비파괴검사학회지
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• 제35권1호
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• pp.1-11
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• 2015

본 연구에서는 온라인 감염 씨감자 비파괴선별 시스템을 구축하고 감염 씨감자 선별을 위한 통계적 모델을 개발하여 적용함으로써 선별시스템의 성능을 평가하였다. 선별모델 개발을 위해 토양병 및 잠복 감염의 대표적인 병원성 세균인 pectobacteruim atrosepticum을 인위적으로 씨감자에 감염시켜 씨감자 내부에 병징이 발현되도록 하여 실험하였다. 구축된 선별시스템을 통해 감염 및 정상 씨감자의 투과스펙트럼을 획득한 후 최소자승판별법(partial least square-discriminant analysis)을 이용하여 감염 씨감자 검출모델을 개발하였다. 개발된 모델의 검정결정계수는($R^2$) 0.943이었고 분류의 정확도는 99%(n=80) 이상으로 우수한 선별성능을 보였다. 개발된 온라인 감염 씨감자 선별시스템은 씨감자 선별뿐만 아니라 다양한 농산물의 감염을 검출하는 기반기술로 응용이 가능할 것으로 판단된다.

• The Plant Pathology Journal
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• 제27권4호
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• pp.315-323
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• 2011

Soybean plants infected with Bean pod mottle virus (BPMV) develop acute symptoms that usually decrease in severity over time. In other plant-virus interactions, this type of symptom recovery has been associated with degradation of viral RNAs by RNA silencing, which is accompanied by the accumulation of virus-derived small interfering RNAs (siRNAs). In this study, changes in the accumulation of BPMV siRNAs were investigated in soybean plants infected with BPMV alone, or infected with both BPMV and Soybean mosaic virus (SMV) and in transgenic soybean plants expressing SMV helper component-protease (HC-Pro). In many potyviruses, HC-Pro is a potent suppressor of RNA silencing. In plants infected with BPMV alone, accumulation of siRNAs was positively correlated with symptom severity and accumulation of BPMV genomic RNAs. Plants infected with both BPMV and SMV and BPMV-infected transgenic soybean plants expressing SMV HC-Pro exhibited severe symptoms characteristic of BPMVSMV synergism, and showed enhanced accumulation of BPMV RNAs and siRNAs compared to plants infected with BPMV alone and nontransgenic plants. Likewise, SMV HC-Pro enhanced the accumulation of siRNAs produced from a silenced green fluorescent protein gene in transient expression assays, while the P19 silencing suppressor of Tomato bushy stunt virus did not. Consistent with the modes of action of HC-Pro in other systems, which have shown that HC-Pro suppresses RNA silencing by preventing the unwinding of duplex siRNAs and inhibiting siRNA methylation, these studies showed that SMV HC-Pro interfered with the activities of RNA-induced silencing complexes, but not the activities of Dicer-like enzymes in antiviral defenses.

• Journal of Chest Surgery
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• 제43권2호
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• pp.199-203
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• 2010

세균성 대동맥류는 드물지만 높은 사망률을 보인다. 세균성 동맥류의 표준적인 치료는 수술적인 방법이지만 그 결과는 실망스럽다. 높은 사망률에 관련된 위험인자로는 대동맥류의 파열과 대동맥류가 신동맥의 상방에 위치하는 경우를 들 수 있다. 세균성 대동맥류의 치료는 대동맥류 제거, 주변 조직의 제거, 감염 부위에서 떨어지게 동맥을 재건하는 수술적 치료와 항생제 치료이다. 신동맥 상방의 대동맥류의 경우는 신동맥 또는 주변 장기로 가는 혈관들의 재이식이 필요하며 인조혈관과 관련된 합병증의 위험성으로 인하여 치료 결과가 좋지 않다. 저자들은 55세 남자 환자에서 신동맥 상방의 감염성 대동맥류를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

• Asian-Australasian Journal of Animal Sciences
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• 제10권5호
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• pp.534-539
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• 1997

A uniform group of 12 upgrade grower goats of 6.0 -7.5 months old were used in this study. They were equally divided into three groups of $T_1$, $T_2$ and $T_3$ and were infected orally with three levels (0, 5,000 and 10,000 larvae) of infective Haemonchus contortus larvae. Before infection, all animals were housed in individual pens with concrete floor. They were provided with a uniform management. Comparison of body weight changes of infected and uninfected grower goats were done using weekly body weights. There was significant (p < 0.01) interaction between the effect of stomach worm infection and duration of infection on body weight. The infected groups (2 and 3) weighed significantly (p < 0.05) less than the control group from week 18 to 21. The animals of control group gained an average of 2.85 kg with 18.75 g average daily gain (ADG) in 152 days, which were significantly higher than those of animals in the infected groups. There was significant effect of H. contortus infection on the pres laughter weights of grower goats. The hot carcass weights of the infected goats were significantly lower than the uninfected group. No significant difference in dressing percentage of infected and uninfected groups was observed.