• Journal of Information Display
• /
• 제4권1호
• /
• pp.34-37
• /
• 2003

We investigate the solid phase crystallization of amorphous Si films on glass substrates under alternating magnetic field induction. The kinetics of crystallization are found to be greatly enhanced by alternating magnetic field. While complete crystallization takes heat treatment of more than 14 hours at 570$^{\circ}C$, it can be reduced by applying the megnetic field to 20 minutes. It is assumed that the enhancement of crystallization is associated with an electromotive force voltage generated by alternating magnetic field. This electric field applied in the amorphous Si may possibly be the reason for acceleration of the atomic mobility of crystallization through the modification of atomic potentials

• 대한전기학회:학술대회논문집
• /
• 대한전기학회 2002년도 학술대회 논문집 전문대학교육위원
• /
• pp.153-157
• /
• 2002

Electricity living body formation operation appliance is using most imports until present. And, because electricity living body formation operation appliance is too expensive, it becomes burden to buy in small scale hospital. Also, problem that economical damage by income is added follows, Therefore, this treatise developed electricity living body formation operation appliance by home production, Ultra high frequency eruption circuit used LC circuit, and output frequency is possible to 8 [MHz], and output voltage amplified maximum 800 [V]. This operation appliance could display size of fixed current. This developed product could microscopic operation fewer than 1 [mm]. This development technology is considered by do metallic surface heat treatment, melting, welding, induction heating device and that can apply to domestic animals surgical operation and so on.

• 한국전기전자재료학회:학술대회논문집
• /
• 한국전기전자재료학회 2002년도 춘계합동학술대회 논문집
• /
• pp.127-132
• /
• 2002

Electricity living body formation operation appliance is using most imports until present. And, because electricity living body formation operation appliance is too expensive, it becomes burden to buy in small scale hospital. Also, problem that economical damage by income is added follows. Therefore, this treatise developed electricity living body formation operation appliance by home production. Ultra high frequency eruption circuit used LC circuit. and output frequency is possible to 8 [MHz], and output voltage amplified maximum 800 [V]. This operation appliance could display size of fixed current. This developed product could microscopic operation fewer than 1 [mm]. This development technology is considered by do metallic surface heat treatment, melting, welding, induction heating device and that can apply to domestic animals surgical operation and so on.

• 한국식품위생안전성학회지
• /
• 제13권2호
• /
• pp.171-187
• /
• 1998

Garlic occupies a special position among the many foods of vegetable origin because it is the sole food for Koreans during the their lives. And vitamin A has been ingested by forms of food or additives. Cadmium has been described as one of the most dangerous trace elements in the food and environment of man and livestocks. Since the de novo synthesis of stress proteins can be detected early after exposure to some agents, analysis of cadmium-induced changes in gene expression , ie. alterations in patterns of protein synthesis, may be useful to develop as biomarkers of exposure and damage for food hygiene. He acute and chronic combine effects of cadmium (Cd, CdCl2 20mg/kg), garlic oil(Dds: diallyl disulfide 50mg/kg, 3 times a week) and vitamin A(Ra: retinol acetate 50,000 IU/kg, 3 times a week) on Wistar male rats were evaluated concerning cadmium contents, tissues enzyme activity, HSP expression histopathological and electron microscopical examinations. The results of the study are as follows ; 1. Less cadmium was absorbed through the digestive tracts, but the ratio of contents in tissue were not changed by the simultaneous adminstration of diallyl disufide or retinol acetate. 2. ALT(alanine aminotransferase) , AST(aspartate aminotransferase), glucose, BUN (blood urea nitrogen), creatinine, the key indices of the clinical changes in hepatic and renal function were significantly hanged by the cadmium treatment after 1 week in liver, after 4 weeks in kidney. 3. Histopathological changes in cadmium treated rats were appeared at 8 weeks age treatment in kidneys. Homogenous eosinophilic material was accumulated in cortical and collecting tubular lumens at 16 weeks. Degenerated or necrotized tubular cells were observed in cortex and medulla. Degenerated seminiferous tubules and homogeneous eosinophilic material was seen in interstitial tissue of rat treated with cadmium for 16 weeks. Calcium deposits were seen in degenerated seminiferous tubules and the tubules showed severe calcification of rat treated with cadmium for 16 weeks. Electron microscope changes in kidney were observed in rats treated with CdCl2 20 mg/kg. Proximal convoluted tubule cells showed selling of cytoplasm and narrow lumen. Capillary endothelial cells showed cytoplasmic vacuoles and swelling. Degenerated epithelial cells were accumulated in tubular lumen of kidney. 4. Enhanced synthesis of 70 KDa relateve molecular mass proteins were detected in 2 hours after cadmium, exposure, with maximum activity occurring at 8~48 hours. Induction of HSP 70 was evident at proximal tubules and glomeruli in kidney. Testicular cells produced enough HSP to be detected normally. From the above results, it could be concluded that HSP70 induction by the cadmium treatment was a rapid reaction to indicated the exposure of xenobiotics, and retinol acetate reduced the cadmium induced nephrotoxicity.

• Journal of Ginseng Research
• /
• 제4권2호
• /
• pp.165-174
• /
• 1980

The concentrated red ginseng extract (RGE) which was prepared from water extract of red ginseng tails was investigated for its changes in color intensity, sugar contents and during storage at various temperatures. In order to evaluate the color of RCE, a spectrophotometric measurement in ultraviolet and visible range was applied. The concentrated RGE was divided into three fractions of aqueous, butanol and benzene layers. It was found that : (1) Increase in RCE color during heat treatment was considered to be due to nonezymatic browning reaction. Water soluble layer showed approximately 100 times higher color intensity than those of organic solvent layers (2) The RCE stored at 8$0^{\circ}C$ showed an increase in fructose and glucose content while a rapid decrease was resulted at 10$0^{\circ}C$. (3) A rapid increase in absorbances at 400 and 460nm was shown at 90 and 10$0^{\circ}C$ after an initial induction period and slowed down after 50 hours . (4) A significant relationship was found between decrease in sugar content and increase in color intensity. (5) Absorbance ratio of 400nm/460nm indicated that benzene layer has about two times higher value in violet color than those of butanol and aqueous layers.

• 한국해양공학회지
• /
• 제23권3호
• /
• pp.30-34
• /
• 2009

Oil hydraulic piston pumps are being extensively used in the world, because of simple design, light weight and effective cost etc. An oil hydraulic pump is likely to have serious problems of high leakage, friction and low energy efficiency according to large time use. In the oil hydraulic piston pumps the clearance between the valve block and piston plays an important role for volumetric and overall efficiency. In this paper, the wear property of the SACM645 material used the hydraulic piston pump has been work out by experimentation with variable heat treatment. To investigate the effect according to the piston surface condition, seven different types specimen were prepared. From the wear test results, induction hardening and nitration were definitely superior to the others. On the whole, nitration was estimated for high strength material to wear resistance.

• 대한한방소아과학회지
• /
• 제32권3호
• /
• pp.90-99
• /
• 2018

Objectives Hwangnyeonhaedok-tang is a Korean herbal medical treatment that removes toxic heat, fever and inflammation. The purpose of this study was to investigate the effect of Hwangnyeonhaedok-tang treatment on the relief of atopic dermatitis (AD) through regeneration of skin lipid barrier. Methods Male NC/Nga mice (20 g, 6 week age) were used. Each 10 mice were allocated to the control group (Ctrl), the AD-induced with no treatment group (AE), and the group which induced AD after administering Hwangnyeonhaedok-tang extract (HT). To induce AD-like skin lesions, sodium dodecyl sulfate (SDS) (Sigma-Aldrich, USA) was rubbed on the back of each mouse to remove the lipid lamella of the stratum corneum, and Dermatophagoides (D.) farinae crude extract was applied. HT group was orally administered Hwangnyeonhaedok-tang after induction of AD. IL-4 IL-13, $p-I{\kappa}B$, iNOS, Sudan Black B (SB), loricrin, and filaggrin were observed to confirm the effect. Results In HT group, AD skin score was decreased by 46%. The cytokine IL-4 and IL-13, which can identify Th2 differentiation, was reduced by 73% and 58% each. Anti-inflammatory effects were observed in $p-I{\kappa}B$ and iNOS by 69% and 54%, respectively. Finally, SB showed that the regeneration of the lipid layer and the increase of the regeneration power of loricrin and filaggrin were increased by 437% and 464%, respectively. Conclusions From the study result, we observed that Hwangnyeonhaedok-tang treatment alleviates AD by decreasing skin score, reducing Th2 differentiation, inducing anti-inflammatory, and increasing skin lipid barrier regeneration. Thus, Hwangnyeonhaedok-tang treatment would be considered as an effective AD relieving treatment.

• Journal of Microbiology and Biotechnology
• /
• 제26권9호
• /
• pp.1517-1526
• /
• 2016

Lactic acid bacteria (LAB) isolated from fermented foods have potential as a treatment for immune-related disorders and the use of LAB has been increasing worldwide. In this study, the differential cytokine regulatory effect was examined with three isolates of lactobacilli strains; namely, Lactobacillus plantarum K55-5 isolated from dairy product, and L. sakei K101 and L. plantarum K8 previously isolated from kimchi (a Korean traditional fermented vegetable). Production of cytokines such as IL-10, IL-12, IFN-γ, and TNF-α was significantly increased in L. sakei K101- and L. plantarum K55-5-treated splenocytes as compared with controls. The oral administration of L. sakei K101 and L. plantarum K55-5 increased cytokine production in the immunosuppressed mouse splenocytes and blood. NK cell cytotoxic activity was also increased in L. sakei K101- and L. plantarum K55-5-fed mice. On the other hand, L. plantarum K8 did not affect cytokine induction in all the experiments performed in this study. The cytokine-inducing effect of L. plantarum K55-5 was significantly increased by lysates of heat-killed bacteria as compared with live, heat-killed, or supernatant of cell lysates. TNF-α production by lipoteichoic acids (LTAs) isolated from the three isolates of lactobacilli was compared, and it was found that K55-5 LTA had a highest cytokine-inducing ability, which was mediated by TLR2-mediated NF-κB and ERK activation. Taken together, our study suggests that L. plantarum K55-5 and L. sakei K101 can be used for the treatment of immunosuppressed disorders.

• 열처리공학회지
• /
• 제28권5호
• /
• pp.239-249
• /
• 2015

Various amount of NbC carbide was intentionally formed in a matrix-type cold-work tool steel by controlled amount of Nb and C addition. And the effect of NbC addition on the mechanical properties was investigated. Four alloys with different Nb and C contents were cast by vacuum induction melting, then hot forging and spheroidizing annealing were conducted. The machinability of the annealed specimens was examined with 3 different cutting tools. And tensile tests at room temperature were conducted. After quenching and tempering, hardness and impact toughness were measured, while wear resistance was evaluated by disk-on-plate type wear test. The increasing amount of NbC addition resulted in degraded machinability with increased strength, whereas the absence of NbC also led to poor machinability due to high toughness. After quenching and tempering, the additional NbC improved wear resistance with increasing hardness, whereas it deteriorated impact toughness. Therefore, it could be found that a moderate addition of NbC was desirable for the balanced combination of mechanical properties.

• The Korean Journal of Physiology and Pharmacology
• /
• 제20권1호
• /
• pp.129-136
• /
• 2016

This study was performed to investigate whether an intra-articular injection of transient receptor potential vanilloid 1 (TRPV1) receptor agonist, resiniferatoxin (RTX) would alleviate behavioral signs of arthritic pain in a rat model of osteoarthritis (OA). We also sought to determine the effect of RTX treatment on calcitonin gene-related peptide (CGRP) expression in the spinal cord. Knee joint inflammation was induced by intra-articular injection of monosodium iodoacetate (MIA, $8mg/50{\mu}l$) and weight bearing percentage on right and left hindpaws during walking, paw withdrawal threshold to mechanical stimulation, and paw withdrawal latency to heat were measured to evaluate pain behavior. Intra-articular administration of RTX (0.03, 0.003 and 0.0003%) at 2 weeks after the induction of knee joint inflammation significantly improved reduction of weight bearing on the ipsilateral hindlimb and increased paw withdrawal sensitivity to mechanical and heat stimuli. The reduction of pain behavior persisted for 3~10 days according to each behavioral test. The MIA-induced increase in CGRP immunoreactivity in the spinal cord was decreased by RTX treatment in a dose-dependent manner. The present study demonstrated that a single intra-articular administration of RTX reduced pain behaviors for a relatively long time in an experimental model of OA and could normalize OA-associated changes in peptide expression in the spinal cord.