• Journal of the Korean Society for Aeronautical & Space Sciences
• /
• v.33 no.11
• /
• pp.74-79
• /
• 2005

Computational studies on the hydrodynamic behavior of the forward-sweep inducers for the rocket-engine turbopump are presented in comparison with the conventional backward- sweep inducers. In the present study, two kinds of forward-sweep inducers are designed and numerically investigated. Forward-sweep inducers have bigger tip solidity compared to backward-sweep inducers even with shorter axial length due to their forward-sweep leading edge profiles. It is shown that back flows at the inlet decreases dramatically for forward- sweep inducers. And the low pressure region at the back flow are also decreased, which is assumed to promote the suction performance of the inducers. It seems that the hub located upstream of the tip at the leading edge induces pre whirl at the inlet blade tip for the backward sweep inducer. And this pre whirl leads to the big back flow.

• Proceedings of the KSME Conference
• /
• 2001.06e
• /
• pp.625-630
• /
• 2001

The inducers in liquid-rocket engines are to increase the inlet pressure of the pump to avoid any malfunction due to cavitation. Inducers are typically designed to be operated with some amount of cavitation for the compactness of the turbopump system. Also, inducers are designed to produce low headrise to prevent the decrease of the overall pump efficiency due to the low efficiency of inducers. In the present paper, a computational study on the hydrodynamic behavior of the inducer for the rocket-engine turbopump are presented including the effect of the mass flow rate under the constant rotational speed. As the mass flow rate is decreased, the inducer showed better performance with strong back flows which may have deleterious effects upon the anti-cavitation ability. But the adopted inducer showed very low headrise with high volume flow rates, which may be caused by the small passage area near the trailing edge. The modified version of the present inducer is proposed and numerically evaluated, which in turn showed better results.

• Biotechnology and Bioprocess Engineering:BBE
• /
• v.11 no.2
• /
• pp.96-99
• /
• 2006

In this study, we have attempted to determine the optimum concentration of inducers responsible for efficient laccase production by the white-rot fungus, Trametes sp. Variations in laccase activity were investigated with changing concentrations of 2,5-xylidine, syringaldazine, ABTS, and guaiacol. Enhancement of peak laccase activity was achieved via the combination of 2,5-xylidine with ABTS, syringaldazine, or guaiacol, resulting in increases of up to 359, 313, and 340%, respectively, as compared to control values. Among the tested inducers, the addition of 0.1mM of ABTS coupled with 1.0mM of 2,5-xylidine in the medium after 24 h of cultivation proved optimal with regard to laccase enzyme production.

• Proceedings of the Korean Society of Soil and Groundwater Environment Conference
• /
• 2003.04a
• /
• pp.340-343
• /
• 2003

Soils contaminated by hazardous hydrophobic organic compounds, such as polycyclic aromatic hydrocarbons (PAHs), have become a major environmental issue due to toxic and carcinogenic properties of those compounds. In this work, we investigated effects of various metabolic inducers on phenanthrene biodegradation. Biodegradation tests were peformed with two different Pseudomonads: Pseudononrdia hydrocarboxydans (Gram positive) and Pseudomonas putida (Gram negative). Intermediates of phenanthrene metabolism (1-hydroxy-2-naphthoate, salicylate, catechol, phthalate and protocatechuate) were selected as inducers. The tests indicated that 1-hydroxy-2-naphthoate was the most effective inducer and enhanced the phenanthrene degradation rate up to 5.7 times, even though all the others also had induction ability to some extent. The effective induction could be achieved even at a low concentration of 1-hydroxy-2-naphthoate. Addition of metabolic inducers would be an attractive trick for the successful bioremediation of PAH-contaminated soil.

• Journal of Korean Ophthalmic Optics Society
• /
• v.8 no.1
• /
• pp.65-71
• /
• 2003

The corneal epithelium is constantly being shed. The mechanism of corneal desquamation is not fully understood. Apoptosis, programmed cell death, may play a role. Apoptosis can be induced by a number of factors and different mechanisms. The study was performed to examine the apoptotic index induced in human corneal epithelial cells maintained in tissue culture by various apoptotic inducers. Various inducers, recombinant human cytokines($INF{\gamma}$, $TNF{\alpha}$, FASAb), actinomycin D. camptothecin, cycloheximide, dexamethasone and etoposide, were purchased from commercial suppliers. Inducers at manufacturer-recommended concentration were added to the corneal epithelial cells for 48 hours. Cell viability was measured using MTT assay. The cells were then assessed for the level of apoptosis. Morphologic changes and quantification of apoptotic cells were determined and counted under fluorescence microscope after inducers-treated human corneal epithelial (HCE) cells for 48 hours with Hoechst 33342 staining. Annexin V-FITC/PI staining and DePsipher assay. The expression of Fas protein was studied by immunocytochemistry. All inducers induced apoptosis in HCE cells in a dose dependent manner. Actinomycin D. camptothecin and etoposide induced apoptosis at lower than manufacturer-recommended concentration, while cytokines, cycloheximide and dexamethasone induced apoptosis at higher concentrations at the end of 48 hours. All inducers elicited typical apoptotic morphologic changes (chromatin condensation, nucleus fragmentations non-orange-red colored mitochondria) and expresses Fas protein highly. Apoptotic index of HCE cells by these inducers was different from the other cell lines. RNA synthesis inhibitor and topoisomerase inhibitors induced apoptosis at lower concentration than manufacturer-recommended concentration. Cytokines, cycloheximide and dexamethasone were able to produce apoptosis at 10 times higher concentrations. RNA synthesis inhibitor and topoisomerase inhibitors are more sensitive than intracellular receptor-activators in apoptotic induction of HCE cells.

• The KSFM Journal of Fluid Machinery
• /
• v.8 no.1 s.28
• /
• pp.23-29
• /
• 2005

Steady and unsteady cavitation characteristics of turbopump inducer were investigated in this paper. To investigate the effect of blade angle on the inducer performance, three inducers with inlet tip blade angle of $7.8^{\circ},\;7.0^{\circ},\;6.1^{\circ}$, respectively, were tested. For $7.8^{\circ},\;7.0^{\circ}$ inducers in the non-cavitating condition, head decreased linearly with flow rate, but head-flow rate curve had a dip at the flow coefficient ${\psi}=0.065$ for $6.1^{\circ}$ inducer. Attached cavitation and cavitation surge were found in the $7.8^{\circ},\;7.0^{\circ}$ inducers in the cavitation tests. During the attached cavitation one cell rotated at the same rotational speed as that of the inducer. The cavitation surge did not rotate and the oscillating frequency was $7{\sim}20\;Hz$. From the curve of the critical cavitation number versus flow rate, it was found that the steady cavitation performance of $6.1^{\circ}$ inducer was much lower than that of $7.8^{\circ},\;7.0^{\circ}$ inducers.

• 유체기계공업학회:학술대회논문집
• /
• 2003.12a
• /
• pp.333-339
• /
• 2003

Steady and unsteady cavitation characteristics of turbopump inducer were investigated in this paper. To see the effect of blade angle on the inducer performance, three inducers with inlet tip blade angle of $7.8^{\circ},\;7.0^{\circ},\;6.1^{\circ}$, respectively, were tested. For $7.8^{\circ},\;7.0^{\circ}$ inducers in the non-cavitating condition, head decreased linearly with flow rate, but head-flow rate curve had a dip at the flow coefficient ${\Phi}=0.065\;for\;6.1^{\circ}$ inducer. Rotating cavitation and cavitation surge were found in the $7.8^{\circ},\;7.0^{\circ}$ inducers in the cavitation tests. During the rotating cavitation one cell rotated at the same rotational speed as that of the inducer. The cavitation surge did not rotate and the oscillating frequency was $7{\sim}20\;Hz$. From the curve of the critical cavitation number versus flow rate, it was found that the steady cavitation performance of $6.1^{\circ}$ inducer was much lower than that of $7.8^{\circ},\;7.0^{\circ}$ inducers.

• Journal of Marine Life Science
• /
• v.8 no.2
• /
• pp.186-189
• /
• 2023

Uncoupling protein 1 (UCP1) is a unique mitochondrial membranous protein expressed in brown adipose tissue (BAT) in mammals. While its expression in response to cold temperatures and adipogenic inducers is well-characterized in mammals and human infants, the molecular characterization and expression of UCP1 in fish remain unexplored. To address this gap, we analyzed UCP1 expression in response to adipogenic inducers in a fish cell line, rainbow trout gonadal cells (RTG-2), and compared it with UCP1 expression in three mammalian preadipocytes, 3T3-L1, T37i, and WT1 exposed to the Peroxisome proliferator-activated receptor gamma (PPARγ) agonists, rosiglitazone (Rosi). In mammalian preadipocytes, UCP1 protein was highly expressed by Rosi, with an induction of adipogenesis observed in a time-dependent manner. This suggests that UCP1 plays a significant role in adipogenesis in mammals. However, RTG-2 cells showed no response to adipogenic inducers and exhibited only marginal expressions of UCP1. These results imply that RTG-2 cells may lack crucial responsive mechanisms to adipogenic signals or that the adipogenic response is regulated by other mechanisms. Further studies are needed to confirm these phenomena in fish preadipocytes when an appropriate cell line is established in future research.

• Mycobiology
• /
• v.41 no.1
• /
• pp.47-55
• /
• 2013

Rhizoctonia solani, Fusarium solani, F. oxysporum, and Macrophomina phaseolina were found to be associated with root rott and wilt symptoms of faba bean plants collected from different fieldes in New Valley governorate, Egypt. All the obtained isolates were able to attack faba bean plants (cv. Giza 40) causing damping-off and root rot/wilt diseases. R. solani isolates 2 and 5, F. solani isolate 8, F. oxysporum isolate 12 and M. phaseolina isolate 14 were the more virulent ones in the pathogenicity tests. Biocontrol agents (Trichoderma viride and Bacillus megaterium) and chemical inducers (salicylic acid [SA] and hydrogen peroxide) individually or in combination were examined for biological control of damping-off and root rot/wilt and growth promoting of faba bean plants in vitro and in vivo. Both antagonistic biocontrol agents and chemical inducers either individually or in combination inhibited growth of the tested pathogenic fungi. Biocontrol agents combined with chemical inducers recorded the highest inhibited growth especially in case SA + T. viride and SA + B. megaterium. Under green house and field conditions, all treatments significantly reduced damping-off and root rot/wilt severity and increased of survival plants. Also, these treatments increased fresh and weights of the survival plants in pots compared with control. The combination between biocontrol agents and chemical inducers were more effective than used of them individually and SA + T. viride was the best treatment in this respect. Also, under field conditions, all these treatments significantly increased growth parameters (plant height and number of branches per plant) and yield components (number of pods per plant and number of seeds per plant, weight of 100 seeds and total yield per feddan) and protein content in both seasons (2010~2011 and 2011~2012). Faba bean seeds soaked in SA + T. viride and SA + B. megaterium were recorded the highest growth parameters and yield components. Generally, the combination between biocontrol agents and chemical inducers recorded the best results for controlling damping-off and root rot/wilt diseases in greenhouse and field with addition improved plant growth and increased yield components in field.

• Journal of Mechanical Science and Technology
• /
• v.18 no.3
• /
• pp.481-490
• /
• 2004

Steady state flow calculations are executed for turbo-pump inducers of modern design to validate the performance of Tascflow code. Hydrodynamic performance of inducers is evaluated and structure of the passage flow and leading edge recirculation are also investigated. Calculated results show good coincidence with experimental data of static pressure performance and velocity profiles over the leading edge. Upstream recirculation, tip leakage and vortex flow at the blade tip and near leading edge are main sources of pressure loss. Amount of pressure loss from the upstream to the leading edge corresponds to that of whole pressure loss through the blade passage. The viscous loss is considerably large due to the strong secondary flow. There appears more stronger leading edge recirculation for the backswept inducer, and this increases the pressure loss. However, blade loading near the leading edge is considerably reduced and cavitation inception delayed.