• 대한치과의사협회지
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• 제54권2호
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• pp.155-162
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• 2016

Radiographs can help in the diagnosis and treatment planning, but the exposure to ionizing radiation may elevate the risk of developing cancer in a person's lifetime. The objective of this review is to briefly summarize 1) radiation risk, especially cancer risks associated with diagnostic imaging, 2) linear, non-threshold (LNT) hypothesis, 3) the risks of radiation exposure to a fetus, and 4) the campaign of Image Gently. The individual risk of radiation-related cancer from any single medical imaging procedure is extremely small and it is not likely to be cancer risk at doses lower than 100 mGy, but patients may be harmed by avoiding diagnostic imaging due to fear of radiation hazard. Dentists need to understand the radiation doses delivered by various radiographic techniques and the acceptable exposure thresholds to effectively advise the patient and to reduce the unnecessary radiation

• Genomics & Informatics
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• 제5권2호
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• pp.41-45
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• 2007

Pharmacogenomics is the study that examines how genetic variations affect the ways in which people respond to drugs. The ways people respond to drugs are complex traits that are influenced by many different genes. Pharmacogenomics intends to develop rational means of optimizing drug therapy, with respect to the patients' genotype, to maximize efficacy with minimal adverse drug reactions. Pharmacogenomics has the potential to revolutionize the practice of medicine, and promises to usher in an area of personalized medicine, in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Indeed, pharmacogenomics is exploited as an essential step for target discovery and drug development in the pharmaceutical industry. The goal of the personalized medicine is to get the right dose of the right drug to the right patient at the right time. In this article, we will review the use of pharmacogenomics in drug discovery and development.

• The Journal of Korean Physical Therapy
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• 제14권3호
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• pp.116-128
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• 2002

Physical therapy record what the therapist dose to manage the individual patients case. The rights of the therapist and patients are protected should any question occur in the future regarding the care provided to the patient. Physical therapy note is a method of communicating with the patient's physician, other health care professionals and including other therapists. Abbreviations and symbols are used as a time and space saver while writing physical therapy Progress note. In order to ensure that everyone in the hospital need understand what has been written in the chart by others. Therefore, we need a enactment of physical therapy abbreviations and symbols in Korea. There are 468 abbreviations and symbols. It will be change with development of medical science, physical therapy and culture.

• The Journal of Korean Physical Therapy
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• 제14권4호
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• pp.234-259
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• 2002

Physical therapy record what the therapist dose to manage the individual patients case. The rights of the therapist and patients are protected should any question occur in the future regarding the care provided to the patient. Physical therapy note is a method of communicating with the patient's physician, other health care professionals and including other therapists. Abbreviations and symbols are used as a time and space saver while writing physical therapy progress note. In order to ensure that everyone in the hospital need understand what has been written in the chart by others. Therefore, we need a enactment of physical therapy abbreviations and symbols in Korea. There are 468 abbreviations and symbols. It will be change with development of medical science, physical therapy and culture.

• Molecules and Cells
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• 제26권3호
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• pp.299-307
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• 2008

To characterize gene expression that is dependent on the strength of calorie restriction (CR), we obtained transcriptome at different levels of glucose, which is a major energy and carbon source for budding yeast. To faithfully mimic mammalian CR in yeast culture, we reconstituted and grew seeding yeast cells in fresh 2% YPD media before inoculating into 2%, 1%, 0.5% and 0.25% YPD media to reflect different CR strengths. We collected and characterized 160 genes that responded to CR strength based on the rigorous statistical analyses of multiple test corrected ANOVA (adjusted p value < 0.1 or raw p value < 0.0031) and Pearson correlation (|r| > 0.7). Based on the individual gene studies and the GO Term Finder analysis of 160 genes, we found that CR dose-dependently and gradually increased mitochondrial function at the transcriptional level. Therefore, we suggest these 160 genes are markers that respond to CR strength and that might be useful in elucidating CR mechanisms, especially how stronger CR extends life span more.

• 한국원자력학회:학술대회논문집
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• 한국원자력학회 1995년도 추계학술발표회논문집(2)
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• pp.879-884
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• 1995

The results of performance assessment analyses have shown that the long-lived radionuclides such as I-129 control the potential individual dose impact to the public. I-129 is difficult-to-measure(DTM) in low-level waste because it is non-gamma emitting radionuclides and exists at extremely low concentrations in radioactive waste generated by nuclear reactors. In this study, computer modeling technique to predict release rate of I-129 is developed to provide another tools far performance assessment of land disposal facilities and characteristics of radwaste. Model suggested in this study will give conservative values of I-129 release rate far determination of radwaste characteristics. More detailed approach is implemented to account for release conditions of fuel source-nuclides. 1-131 concentration measured from reactor coolant and released fraction from tramp fuel have dominant roles in calculating release rate of I-129 with fuel defect conditions.

• Radiation Oncology Journal
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• 제36권2호
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• pp.85-94
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• 2018

Radiation-induced second malignancies (RISM) is one of the important late side effects of radiation therapy and has an impact on optimal treatment decision-making. Many factors contribute to the development of RISM such as age at radiation, dose and volume of irradiated area, type of irradiated organ and tissue, radiation technique and individual and family history of cancer. Exact mechanism of RISM is unknown. But nowadays, it is a growing concern in oncology because of the increased number of cancer survivors and efforts are being made to prevent or decrease the incidence of RISM. The primary search for articles was carried via Google Scholar and PubMed with keywords included 'radiation induced malignancies, second malignancies, and chemotherapy induced malignancies'. Additional papers were found through references from relevant articles. In this review article, we have discussed about the pathogenesis, factors contributing to RISM, screening and prevention strategies of RISM.

• Nuclear Engineering and Technology
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• 제37권2호
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• pp.185-190
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• 2005

The Korea Institute of Radiological and Medical Sciences (KIRAMS) electron microbeam system has been built with its prototype components. The system is composed of an electron gun, a beam transport chamber, and a cell image acquisition and positioning stage. Each component has been upgraded through repetitive performance tests for various parametric arrangements. This paper presents the preliminary results of the performance test on the beam control and detection parts of the system.

• Plant Resources
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• 제8권2호
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• pp.103-109
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• 2005

Lettuce (Lactuca sativa L.) is known to contain water-soluble substances that improve antioxidant status due to the richness in antioxidants. Greenhouse experiment was carried out under different shading conditions during spring lettuce growing season. Shade significantly reduced shoot weight, number of leaves and chlorophyll content, while it increased shoot length of lettuce plants. The antioxidant potential of the individual fraction was in order of n-butanol > ethyl acetate > water > n-hexane fraction, although was less than that of commonly used antioxidants, BHT and ascorbic acid. Fractions from lettuce plants dose-dependently increased DPPH free radical scavenging activity, in vitro test. By means of HPLC analysis, BuOH fraction of cultivar 'Hwahyang' (57.93 mg $100g^{-1}$) had the highest amount of antioxidant chi orogenic acid. Shading treatment increased average amount of chlorogenic acid of all cultivars in BuoH, EtOAc, hexane and water fractions by 33, 120, 144, and $58\%$, respectively. These results suggest that lettuce plants had potent antioxidant activity, and their activities were differently exhibited depending on cultivar and fraction.

• KDI Journal of Economic Policy
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• 제24권2호
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• pp.83-119
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• 2002

In this paper, we study the relationship between the U.S. daily stock returns and the corresponding Korean returns. More specifically, we examine whether the previously realized U.S. stock returns would help predict the current Korean returns. We find that for dose-to-close daily stock returns, the U.S. returns would help predict the Korean returns. However, for open-to-close stock returns, the U.S. intraday stock returns would not help predict the corresponding Korean returns. After distinguishing investors by their nationality and types, we then examine whether there is a relationship between investors' net purchase of Korean stocks and the previous days' U.S. stock returns. We find that the amount of international investors' net purchase of Korean stocks today would vary significantly with the previous days' U.S. stock returns. The Korean individual investors and the Korean investment trust companies, however, would follow the opposite investment pattern.