• Asian Pacific Journal of Cancer Prevention
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• 제15권15호
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• pp.6177-6180
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• 2014

Background: Our study objectives were to evaluate the medical economics of cervical cancer prevention and thereby contribute to cancer care policy decisions in Japan. Methods: Model creation: we created presence-absence models for prevention by designating human papillomavirus (HPV) vaccination for primary prevention of cervical cancer. Cost classification and cost estimates: we divided the costs of cancer care into seven categories (prevention, mass-screening, curative treatment, palliative care, indirect, non-medical, and psychosocial cost) and estimated costs for each model. Cost-benefit analyses: we performed cost-benefit analyses for Japan as a whole. Results: HPV vaccination was estimated to cost $291.5 million, cervical cancer screening $76.0 million and curative treatment $12.0 million. The loss due to death was $251.0 million and the net benefit was -$128.5 million (negative). Conclusion: Cervical cancer prevention was not found to be cost-effective in Japan. While few cost-benefit analyses have been reported in the field of cancer care, these would be essential for Japanese policy determination.

• Safety and Health at Work
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• 제9권4호
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• pp.434-440
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• 2018

Background: In industrial countries, home care of community dwelling elderly people is rapidly growing. Frequent injuries in home caregivers result from slips, trips, and falls (STFs). The current study tests attentional cognitive failure to mediate the association between work stressors and STFs. Methods: A sample of 125 home caregivers participated in a questionnaire study and reported work interruptions, unreasonable tasks, quality-threatening time pressure, conscientiousness, attentional cognitive failures, and STFs. Results: In structural equation modeling, the mediation model was shown to fit empirical data. Indirect paths with attentional cognitive failures as the link between work stressors and STF were all significant in bootstrapping tests. An alternative accident-prone person model, that suggests individual differences in conscientiousness to predict attentional cognitive failures that predict more frequent work stressors and STFs, showed no significant paths between work conditions and STFs. Conclusion: To prevent occupational injury, work should be redesigned to reduce work interruptions, unreasonable tasks, and quality-threatening time pressure in home care.

• Tuberculosis and Respiratory Diseases
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• 제67권2호
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• pp.95-104
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• 2009

Background: The pathophysiologic mechanisms of early acute lung injury (ALI) differ according to the type of primary insult. It is important to differentiate between direct and indirect pathophysiologic pathways, and this may influence the approach to treatment strategies. NF-$\kappa$B decoy oligodeoxynucleotide (ODN) is a useful tool for the blockade of the expression of NF-$\kappa$B-dependent proinflammatory mediators and has been reported to be effective in indirect ALI. The purpose of this study was to investigate the effect of NF-$\kappa$B decoy ODN in the lipopolysaccharide (LPS)-induced direct ALI model. Methods: Five-week-old specific pathogen-free male BALB/c mice were used for the experiment. In the preliminary studies, tumor necrosis factor (TNF)-$\alpha$, interleukine (IL)-6 and NF-$\kappa$B activity peaked at 6 hours after LPS administration. Myeloperoxidase (MPO) activity and ALI score were highest at 36 and 48 hours, respectively. Therefore, it was decided to measure each parameter at the time of its highest level. The study mice were randomly divided into three experimental groups: (1) control group which was administered 50 ${\mu}L$ of saline and treated with intratracheal administration of 200 ${\mu}L$ DW containing only hemagglutinating virus of Japan (HVJ) vector (n=24); (2) LPS group in which LPS-induced ALI mice were treated with intratracheal administration of 200 ${\mu}L$ DW containing only HVJ vector (n=24); (3) LPS+ODN group in which LPS-induced ALI mice were treated with intratracheal administration of 200 ${\mu}L$ DW containing 160 ${\mu}g$ of NF-$\kappa$B decoy ODN and HVJ vector (n=24). Each group was subdivided into four experimental subgroups: (1) tissue subgroup for histopathological examination for ALI at 48 hours (n=6); (2) 6-hour bronchoalveolar lavage (BAL) subgroup for measurement of TNF-$\alpha$ and IL-6 in BAL fluid (BALF) (n=6); (3) 36-hour BAL subgroup for MPO activity assays in BALF (n=6); and (4) tissue homogenate subgroup for measurement of NF-$\kappa$B activity in lung tissue homogenates at 6 hours (n=6). Results: NF-$\kappa$B decoy ODN treatment significantly decreased NF-$\kappa$B activity in lung tissues. However, it failed to improve the parameters of LPS-induced direct ALI, including the concentrations of tumor necrosis factor-$\alpha$ and interleukin-6 in BALF, myeloperoxidase activity in BALF and histopathologic changes measured by the ALI score. Conclusion: NF-$\kappa$B decoy ODN, which has been proven to be effective in indirect models, had no effect in the direct ALI model.

• 한국보육지원학회지
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• 제13권1호
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• pp.107-124
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• 2017

Objectives: The purpose of this study was to investigate the effects of children's pride and shame on their interactive peer play, mediated by their daily stress. Methods: The participants of this study were 172 five-year-old children (80 boys and 92 girls) attending kindergartens or child-care centers in Chungbuk, Korea. The data were analyzed by descriptive and correlational analyses, and structural equation modeling using SPSS 19.0 and AMOS 21.0. Results: Children's shame had a significant indirect effect on their interactive peer play, including play-disruption, play-disconnection and play-interactions, mediated by daily stress; children's shame had a significant direct effect on play interaction. However, children's pride did not have a direct effect on daily stress and an indirect effect on their interactive peer play. In other words, high levels of shame among children led to high perceived daily stress. In turn, perceived daily stress increased play-disconnection and play-disruption, while it decreased play-interactions. Meanwhile children's shame led to a low level of play-interaction among young children. Conclusion/Implications: The results imply that children's perceived shame would influence their behaviors in social contexts as well as their psychological wellbeing such as the level of daily stress.

• Asian Pacific Journal of Cancer Prevention
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• 제14권9호
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• pp.5049-5054
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• 2013

Background: To assess the treatment pattern and expenditure incurred by cancer patients undergoing treatment at government tertiary hospitals in India. Materials and Methods: A cross-sectional study of 508 cancer patients randomly selected from tertiary cancer hospitals funded by central/state governments located in major cities of five states in India, namely Kerala, Maharashtra, Rajasthan, West Bengal and Mizoram, during March - May 2011 was conducted. Information related to direct costs, indirect costs and opportunity costs incurred on investigations and treatment, major source of payment and difficulties faced by patients during the course of treatment was collected. Results: About 45% of the patients used private health facilities as the first point of contact for cancer related diseases as against 32% in public hospitals. About 47% sought private health facilities for cancer investigations, 21% at district/sub-district hospitals, and about 4% contacted primary health care facilities. A majority of the patients (76%) faced financial problems while undergoing treatment. Conclusions: The results highlight the importance of involving the primary health care system in the cancer prevention activities.

• 한국보육지원학회지
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• 제18권1호
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• pp.51-70
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• 2022

Objective: In order to promote the rights of childcare teachers, there is a need to identify problems and demands about the rights of childcare teachers. Therefore, this study sought to examine the perception of childcare teachers' rights in order to identify the concepts of teacher rights. Methods: This study used the concept mapping method to identify the concepts of childcare teachers' teacher rights and interpreted these concepts utilizing the multi-dimension analysis method. Results: As a result of interviews from eight childcare teachers, 37 statements were derived. The result of similarities evaluated by 28 childcare teachers showed that 37 statements about teachers' rights consisted of two dimensions and four clusters (direct-indirect and indoor-outdoor of day-care center). Conclusion/Implications: This study suggested that direct and indirect efforts are needed to enhance the rights of childcare teachers and that change is necessary not only within daycare centers such as the principal but that change is also necessary outside daycare centers such as at government agencies in relation to daycare teachers's rights.

• 임상간호연구
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• 제22권1호
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• pp.88-98
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• 2016

Purpose: The purpose of this study was to construct and test a structural equation model of burnout of the critical care nurses based on the job demand-resource model. Methods: A structured questionnaire was completed by 414 critical care nurses. The relationships between concepts of job stress, empathic ability, resilience, job satisfaction, compassion fatigue and burnout were analyzed. Using SPSS WIN 22.0 and AMOS 22.0 programs, the direct and indirect effects of factors affecting burnout among critical care nurses were calculated and modelled. Results: The modified model was yielded as follows: Chi-square= 216.59, GFI= .93, AGFI= .89, NFI= .90, CFI= .93, RMSEA= .07, SRMR= .06 and showed good fit indices. Job satisfaction and compassion fatigue had mediation effects between other three exogenous variables and burnout. Conclusion: The major findings of this study indicate that it is important to develop a support program for critical care nurse in order to improve their job satisfaction and ameliorate their compassion fatigue.

• 한국응급구조학회지
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• 제9권1호
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• pp.101-109
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• 2005

The purpose of this study which was done by 250 Prehospital Care Reports(PCRs) survey of some squads in Seoul Metropolitan Fire & Disaster Management Department was to improve prehospital emergency care by means of quality management. The data were collected in 3 squads from Jun. 21 to Jul. 18, 2004 and analyzed by using SPSS Win 12.0 Version. The conclusions from this study were summarized as follows. The mean time of Event to treatment interval was $4.6{\pm}4.3$ minutes and 49.2% arrived at patient within 4 minutes. Platinum minute was observed 61.1% of verbal response, 73.3% of painful response, 77.8% of unresponsive. The great majority of patients couldn't receive advanced life support on account of limited scope of practice and strict direct medical control in the Emergency Medical Services Act. Data from quality improvement activity will be useful to expand indirect medical control which is able to activate prehospital care. To utilize PCR for quality improvement. It has to have data elements, run data, patient data, check boxes, narrative including US DOT's minimum data set.

• 노인간호학회지
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• 제20권sup1호
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• pp.144-153
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• 2018

Purpose: The purpose of this study was to review the influence of robot systems on nursing and robotics technology. Methods: The research design was a review article. The literature was done to help understand the current status and effects of robotic technology in the healthcare field, both domestic and overseas. The keywords searched were 'Nursing', 'Robot', and 'Patient safety' in Pubmed, CINAHL etc, and 'Nursing Activity', 'Nursing Care Integration Service' in RISS and KISS. Results: In healthcare, robotics is used in five areas; personal care robots, mobility and transfer robots, cognitive and emotional robots, nursing assist robots and care robots in palliative home care settings. Nurses' demands for utilization of robotic systems are high. Especially, if robotics is used for indirect and non-value-added nursing activities, efficiency may increase. Therefore, robotics should be used to help nurses focus on bedside care and perform better nursing care. Conclusion: Future robots and technology can help nurse to provide optimal nursing to patients, and will improve the quality life of patients. It is suggested that nursing research should be actively pursued in the future. Especially, it is an urgent field to improve nursing quality and reduce the burden of nurses.

• 중환자간호학회지
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• 제15권3호
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• pp.12-22
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• 2022

Purpose : This study aimed to examine the relationships of burnout and compassion competency with job satisfaction among nurses working in the intensive care units and emergency rooms. Methods : A correlational survey was conducted from August 1 to August 14, 2018 and involved in 102 nurses working at four university hospitals for more than 1 year. A structured questionnaire was used to measure burnout, compassion competency, and job satisfaction, and data were analyzed using hierarchical multiple regression and mediation effect analysis. Results : The mean scores of burnout, compassion competency, and job satisfaction were 2.58, 4.35, and 2.95, respectively. Burnout and compassion competency along with working night shifts and a wish to transfer explained 35.3% of variance in job satisfaction. Compassion competency showed a small but significant mediating effect in the relationship between burnout and job satisfaction (indirect effect -.0446, 95% CI -.1133, -.0075). Conclusion : Burnout and compassion competency were the significant influencing factors of job satisfaction among nurses working in intensive care units and emergency rooms. Since compassion competency showed a significant mediating effect, further studies should focus on intervention strategies for compassion competency to improve job satisfaction in this population.