• Annals of Clinical Neurophysiology
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• v.19 no.2
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• pp.125-130
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• 2017

Background: Routine nerve conduction study (NCS) can only be used to evaluate the function of large fibers, and the results of NCS are often normal in patients with distal sensory polyneuropathy. The measurement of the current perception threshold (CPT) has been reported to represent a variety of peripheral nerve fiber functions. This study was performed to investigate the value of measuring CPT in patients with diabetic sensory polyneuropathy who have no abnormalities in routine NCS. Methods: Twenty-seven diabetic patients with sensory polyneuropathy and normal routine NCS and 18 age-matched control subjects participated in this study. The CPT was measured on the unilateral index finger and great toe of each subject at frequencies of 5 Hz, 250 Hz, and 2,000 Hz. Results: CPT values were significantly higher in the patient group than in the control group, especially with stimuli at the lowest frequency of 5 Hz (p < 0.05). There were significant correlations between the CPT values obtained at three different frequencies in the patient group, whereas the correlation was only significant in the pair of 250 Hz/5 Hz (both in the hands and feet), and in the pair of 2,000 Hz/250 Hz (in the feet) for the control group. Conclusions: Our data suggest that the CPT test, especially at a stimuli frequency of 5 Hz, may be a useful screening tool for diabetic polyneuropathy in patients who show no abnormalities in routine NCS.

• Korean Journal of Medicinal Crop Science
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• v.11 no.5
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• pp.402-407
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• 2003

Karyotype analysis and chromosomal localization of 5S and 45S rDNAs using multi-color fluorescence in situ hybridization (McFISH) technique were carried out in Bupleurum longeradiatum. Somatic metaphase chromosome number was 2n=12. Karyotype was composed of three pairs of metacentrics (No.3, 4 and 6) and three pairs of submetacentrics (No. 1, 2 and 5). The length of somatic prometaphase chromosomes ranges from 2.55 to $5.05{\mu}m$ with total length of $18.15\;{\mu}m$. In FISH experiment, one pair of 5S rDNA signals was detected on the pericentromeric region of chromosome 4 and one pair of 45S rDNA signals was detected on the telomeric region of chromosome 2.

• Journal of KIISE:Databases
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• v.32 no.3
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• pp.334-343
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• 2005

Complex queries such as path alld twig patterns have been the focus of much research on processing XML data. Structural join algorithms use a form of encoded structural information for elements in an XML document to facilitate join processing. Recently, structural join algorithms such as Twigstack and TSGeneric- have been developed to process such complex queries, and they have been shown that the processing costs of the algorithms are linearly proportional to the sum of input data. However, the algorithms have a shortcoming that their processing costs increase with the length of a queery. To overcome the shortcoming, we propose the segment join technique to augment the structural join with structural indexes such as the 1-Index. The SegmentTwig algorithm based on the segment join technique performs joins between a pair of segments, which is a series of query nodes, rather than joins between a pair of query nodes. Consequently, the query can be processed by reading only a query node per segment. Our experimental study shorts that segment join algorithms outperform the structural join methods consistently and considerably for various data sets.

• Archives of Pharmacal Research
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• v.22 no.4
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• pp.335-339
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• 1999

The oxidation-reduction potentials of cosmetic raw materials, showing tyrosinase inhibitory action, and phenolic compounds structurally similar to L-tyrosine were determined by cylcic voltammetry. The voltammograms obtained could be classified ito 4 patterns (patterns 1-4). Patterns 1, characterized by oxidation and reduction peaks as a pair, was observed with catechol, hydroquinone or phenol, and pattern 2 exhibiting another oxidation peak in addition to oxidation and reduction peaks as a pair was found with arbutin, kojic acid, resorcinol, methyl p-hydroxybenzoate and L-tyrosine as the substrate of tyrosinase. Pattern 3 with an independent oxidation peak only was expressed by L-ascorbic acid, and pattern 4 with a reduction peak only at high potentials, by hinokitiol. The tyrosinase inhibitory activity of these compounds was also evaluated using the 50% inhibitory concentration ($IC_{50}$) and the inhibition constant (Ki) as parameters. Hinokitiol, classified as patterns 4, showed the highest inhibitory activity (lowest $IC_{50}$ and Ki). Hydroquinone showing the second highest activity belonged to pattern 1, which also included compounds exhibiting pattern 2 was relatively low with Ki values being in the order of 10-4 M. Although there was no consistent relationship between oxidation-reduction potentials and tyrosinase inhibitory action, the voltammetry data can be used as an additional index to establish the relationship between the structure and the tyrosine inhibitory activity.

• Journal of the Ergonomics Society of Korea
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• v.29 no.6
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• pp.889-895
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• 2010

This study compared the effects of craniocervical flexion exercise with conservative cervical flexion exercise in workers with chronic neck pain. Subjects were randomly allocated to two groups: control (n=20) and experimental group (n=20), respectively. The conservative exercise for the control group consisted of cervical flexion exercise, whereas the experimental group performed a craniocervical flexion exercise. To compare the two groups, the visual analogue scale (VAS) for a pain, neck disability index (NDI) for a neck disability scale, and cross sectional area (CSA) of longus colli muscle using ultrasound image were assessed on pre-intervention, post-intervention, and 2 weeks follow-up. 2-way repeated ANOVA was used with Bonferroni post-hoc test. (1) There were significant main effects (within and between groups) (p<0.05) and interaction effect (p<0.05) in VAS. Post-hoc test revealed that there were significant differences in all pair-wise comparisons. (2) There were significant main effects (within and between groups) (p<0.05) and interaction effect (p<0.05) in NDI. Post-hoc test revealed that there were significant differences between pre-intervention and post-intervention, pre-intervention and 2 weeks follow-up. (3) There were significant main effects (within and between groups) (p<0.05) and interaction effect (p<0.05) in CSA of longus colli muscle. Post-hoc test revealed that there were significant differences in all pair-wise comparisons. The findings indicate that craniocervical flexion exercise are more effective for improving pain, neck disability, and CSA of longus colli muscle than cervical flexion exercise in workers with chronic neck pain.

• Journal of the Korea Computer Graphics Society
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• v.17 no.3
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• pp.9-19
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• 2011

Computing triangle-triangle intersections has been a fundamental task required for many 3D geometric problems. We propose a novel robust GPU algorithm to efficiently compute intersections in a large triangle set. The algorithm has three stages:k-d tree construction, triangle pair generation, and exact intersection computation. All three stages are executed on GPU except, for unsafe triangle pairs. Unsafe triangle pairs are robustly handled by CLP(controlled linear perturbation) on a CPU thread. They are identified by floating-point filtering while exact intersection is computed on GPU. Many triangles crossing a split plane are duplicated in k-d tree construction, which form a lot of redundant triangle pairs later. To eliminate them efficiently, we use a split index which can determine redundancy of a pair by a simple bitwise operation. We applied the proposed algorithm to computing 3D Minkowski sum boundaries to verify its efficiency and robustness.

• Journal of Aquaculture
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• v.16 no.3
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• pp.179-186
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• 2003

Reproductive cycle, gonadal development and the spawning period of the Korean anchovy Coilia nasus were investigated by histologhical observations. Samples were collected at the coastal area of Geumgang dyke which is connected to Gunsan and Janghang, Korea, from February 2002 to January 2003. C. nasus is dioecious; the ovary consists of a pair of saccular structure with many ovarian lobules, and the testis consists of a pair of lobular structure with many testicular lobules and connected to the posterior seminal vesicle. Monthly changes in the gonadosomatic index (GSI) began to increase in April when seawater temperature increased and reached the maximum in June when the ovary was getting mature, the summer season of longer day length with higher water temperature. The reproductive cycle can be classified into five successive stage in females: early growing stage (February to March), late growing stage (March to April), mature stage (May to June), ripe and spent stage (June to July), and recovery and resting stage (July to January): in males, the cycle can be divided into four successive stages; growing stage (February to April), mature stage (May to July), ripe and spent (June to July), and recovery and resting stages (July to January). According to the frequency distributions of egg diameters in the spawning season. C. nasus is presumed to be summer spawning species and polycyclic species to spawn 2 times or more during the spawning season.

• Journal of the Korean Vacuum Society
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• v.15 no.2
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• pp.152-161
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• 2006

In order to test the capacity of Si(5 5 12) as a potential template for nanowire fabrication, Bi/Si(5 5 12) system has been studied by STM. With Bi deposition, Si(5 5 12) has been transformed to Si(3 3 7) terrace. Initially Bi atoms selectively replace Si-dimers and Si-adatoms with Bi-dimers and Bi-adatoms, respectively. With extended Bi adsorption, Bi-dimers adsorb on the pre-adsorbed Bi-dimers and Bi-atoms. These dimers in the second layer form Bi-dimer pairs having relatively stable $p^3$ bonding, Finally, the Bi-dimer adsorbs on the Bi-dimers in the second layer and saturates. It can be deduced that both surface transformation to (3 3 7) and site-selective Bi adsorption are possible due to substrate-strain relaxation through inserting Bi atoms into subsurface of Si substrate.

• Journal of the Institute of Electronics and Information Engineers
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• v.52 no.7
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• pp.63-73
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• 2015

In the end to end data transfer protocols, it is very important to correctly estimate available bandwidth. In UDT (UDP based Data Transfer), receiver estimates the MTR (Maximum Transfer Rate) of the current link using pair packets transmitted periodically from sender and, then sender finally decides the MTR through EWMA (Exponential Weighted Moving Average) algorithm. Here, MTR has to be exactly estimated because available bandwidth is calculated with difference of MTR and current transfer rate. However, when network is congested due to traffic load and where competing flows are coexisted, it bring about a severe fairness problem. This paper proposes a congestion degree based MTR estimation algorithm. Here, the congestion degree stands a relative index for current congestion status on bottleneck link, which is calculated with arriving intervals of a pair packets. The algorithm try to more classify depending on the congestion degree to estimate more actual available bandwidth. With the network simulation results, our proposed method showed that the fairness problem among the competing flows is significantly resolved in comparison with that of UDT.

• Genomics & Informatics
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• v.14 no.4
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• pp.181-186
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• 2016

Glucose tolerance tests have been devised to determine the speed of blood glucose clearance. Diabetes is often tested with the standard oral glucose tolerance test (OGTT), along with fasting glucose level. However, no single test may be sufficient for the diagnosis, and the World Health Organization (WHO)/International Diabetes Federation (IDF) has suggested composite criteria. Accordingly, a single multi-class trait was constructed with three of the fasting phenotypes and 1- and 2-hour OGTT phenotypes from the Korean Association Resource (KARE) project, and the genetic association was investigated. All of the 18 possible combinations made out of the 3 sets of classification for the individual phenotypes were taken into our analysis. These were possible due to a method that was recently developed by us for estimating genomic associations using a generalized index of dissimilarity. Eight single-nucleotide polymorphisms (SNPs) that were found to have the strongest main effect are reported with the corresponding genes. Four of them conform to previous reports, located in the CDKAL1 gene, while the other 4 SNPs are new findings. Two-order interacting SNP pairs of are also presented. One pair (rs2328549 and rs6486740) has a prominent association, where the two single-nucleotide polymorphism locations are CDKAL1 and GLT1D1. The latter has not been found to have a strong main effect. New findings may result from the proper construction and analysis of a composite trait.