• Title/Summary/Keyword: index compound

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Comparison of Index Compound Content and Anti-inflammatory Activity of Eucommiae Cortex by Various Drying Methods (두충의 건조법별 지표성분 및 항염증 활성 비교)

  • Do, Ho-Jeong;Lee, Jin-Ho;Ha, In-Hyuk;Chung, Hwa-Jin;Lee, Jae-Woong;Kim, Min-Jeong;Kim, Eun-Jee;Lee, In-Hee
    • Journal of Korean Medicine Rehabilitation
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    • v.27 no.1
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    • pp.19-25
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    • 2017
  • Objectives Eucommiae cortex is one of the frequently used herbs for musculoskeletal disorders, with well-known anti-inflammatory effect. Meanwhile, powdered form of herbal drugs is more advantageous than decoction form, in that storing and taking is more convenient. Thus, the authors aimed to investigate whether the drying method affects the index compound level and anti-inflammatory effect of eucommiae cortex water extract. Methods Eucommiae cortex was extracted in distilled water at $100^{\circ}C$ for 3 hours, filtered, and then evaporated under vacuum. One half of the sample was freeze-dried at $-80^{\circ}C$. Another half of the sample was added with dextrin and then spray-dried at $180^{\circ}C$. To assess the possible change in index compound content, pinoresinol diglucoside was selected as the index marker. The content level of the index compound in various extract sample was quantified through high performance liquid chromatography. In addition, iNOS assay in LPS-induced RAW 264.7 cells was adopted to determine the anti-inflammatory effect of various extract samples. Furthermore, MTT assay was performed to confirm that the result of iNOS assay was not due to cytotoxicity. Results There was no significance difference in index compound content between extract samples obtained through two different drying methods. Anti-inflammatory activity of extract samples were similar at the matching concentration, regardless of the drying methods. Extract samples did not show any significant cytotoxicity. Conclusions Extract samples of eucommiae cortex were obtained through freeze-drying and spray-drying. Neither change in index compound content nor difference in anti-inflammatory activity was observed between drying methods.

Brain-to-blood efflux transport of taurine at the blood-brain barrier in rats

  • Lee, Na-Young;Kang, Young-Sook
    • Proceedings of the PSK Conference
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    • 2003.04a
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    • pp.200.1-200.1
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    • 2003
  • The purpose of this study is to examine whether an brain to blood efflux system for taurine is present on the blood-brain barrier (BBB) or not and this efflux transport system is regulated by CNS cell damage with oxidative stress agent such as diethyl maleate (DEM) or tumor necrosis factor-a (TNF-${\alpha}$), by using the brain efflux index (BEI) method. The brain efflux index value is defined as the relative amount of test compound efflux from cerebrum compared with that of a reference compound, [$\^$14/C] carboxyinulin, which has limited BBB permeability. (omitted)

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Anti-Flammability for EEA-VLDPE compound using $Mg(OH)_2$ (EEA-VLDPE compound의 $Mg(OH)_2$ 혼합에 의한 난연성)

  • 이상석;김경태;원성호;김장규;김남기
    • Journal of the Korean Society of Safety
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    • v.13 no.3
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    • pp.96-101
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    • 1998
  • In order to study the change in mechanical properties and anti-flammablilty of ethylene-ethylacrylate copolymer(EEA) very low density polyethylene(VLDPE) compound that could be used as communication cable sheath using $Mg(OH)_2$ as a non-toxic flame retardant, 100, 125, and 150phr $Mg(OH)_2$ were added to 100 parts of EEA-VLDPE compound, 100 EEA : 0 VLDPE, 50 EEA : 50 VLDPE, and 0 EEA : 100 VLDPE, respectively. $Mg(OH)_2$ was a good non-toxic flame retardant for communication cable sheath and anti-flammability increased with the amount of $Mg(OH)_2$ in compound. The mechanical properties-MI, Ts, and Eb-decreased with increasing in the mixing ratio of EEA but oxygen index(OI) increased with increasing in the amount of EEA. The best composition of $Mg(OH)_2$ in this study was 150phr to 50 EEA : 50 VLDPE compound for the anti-flammability.

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A Study on Perpendicular Flame Retardant Characteristic Improvement of Halogen-free Flame Retardant Compounds by Nanoclay Addition (나노클레이 첨가에 따른 할로겐프리 난연컴파운드의 수직난연 특성 향상에 관한 연구)

  • Hwang, Chan-Yun;Yang, Jong-Seok;Seong, Baeg-Yong;Kim, Ji-Yeon;Park, Dae-Hee
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.28 no.1
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    • pp.51-56
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    • 2015
  • The object of this study is to obtain the optimum mix proportion of halogen free compound with flame resistance and, for the purpose, thermal/electrical characteristics test are conducted using compatibilizing agents, flame resistance agents, hydroxide aluminum, sunscreen, antioxidant and silicon oil on the base resin of linear low density polyethylene (LLDPE), Ethylene vinyl acetate copolymer (EVA). Existing compound method accompanies many requirements to be satisfied including a lot of addition of flame resistance agents, prohibition of impact on mixing capability with base and property and etc. In this study, different from the existing method, the optimum mix proportion is determined and experimented by adding nano clay. Oxygen index test shows no difference between specimens while T-6, T-9 shows oxygen index of 29[%] and 26[%], respectively. This is concluded that hydroxide aluminum, which is a flame resistance agent, leads low oxygen index. From UL94-V vertical flame resistance test, the combustion behavior is determined as V-0, Fail based on UL94-V decision criteria. Viscometry shows low measurements in specimens with separate addition of compatibilizing agents or nano clay. Volume resistivity test shows low measurement mainly in specimens without compatibilizing agents. Therefore, with the flame resistance compound shows better performance for thermal/electrical property and the optimum mix proportion are achieved among many existing materials.

Integrated Indexing Method using Compound Noun Segmentation and Noun Phrase Synthesis (복합명사 분할과 명사구 합성을 이용한 통합 색인 기법)

  • Won, Hyung-Suk;Park, Mi-Hwa;Lee, Geun-Bae
    • Journal of KIISE:Software and Applications
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    • v.27 no.1
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    • pp.84-95
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    • 2000
  • In this paper, we propose an integrated indexing method with compound noun segmentation and noun phrase synthesis. Statistical information is used in the compound noun segmentation and natural language processing techniques are carefully utilized in the noun phrase synthesis. Firstly, we choose index terms from simple words through morphological analysis and part-of-speech tagging results. Secondly, noun phrases are automatically synthesized from the syntactic analysis results. If syntactic analysis fails, only morphological analysis and tagging results are applied. Thirdly, we select compound nouns from the tagging results and then segment and re-synthesize them using statistical information. In this way, segmented and synthesized terms are used together as index terms to supplement the single terms. We demonstrate the effectiveness of the proposed integrated indexing method for Korean compound noun processing using KTSET2.0 and KRIST SET which are a standard test collection for Korean information retrieval.

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Effects of 4-t-octylphenol and Nonylphenol on the Reproduction of the Striped Field Mouse (4-t-octylphenol과 nonylphenol이 등줄쥐의 번식에 미치는 영향)

  • Kim, Ji-Hye;Yoon, Myung-Hee
    • Journal of Environmental Science International
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    • v.23 no.2
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    • pp.313-322
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    • 2014
  • To investigate the effects of octylphenol and nonylphenol on the reproduction of the striped field mouse, the mice were subcutaneousely injected with 4-t-octylphenol 800 mg/kg (OP800), nonylphenol 900 mg/kg (NP900) or OP800 + NP900 (OPNP), respectively, in two times a week for 2 months. As the results, there were no differences between the control and the compound-treated groups in the body weight in both sexes, and the GSI (gonadosomatic index) and SVI (seminal vesicles index) in the adult males. But histological abnormalities of the reproductive organs in the mice seems to be related to the compound. This suggestion is supported by the facts that most mice treated with the compounds had only a small number of spermatozoa in the shrunken epididymal tubules. In addition, the shrunken reproductive organ in one mouse treated with the NP, suggests that the abnormalities in the wild striped field mice might be induced by the compound. Furthermore, it is indicated that the compounds must be toxicants to inhibit pregnancy, judging from the fact that all the mice treated with the compounds had failed to deliver.

A Study on Curing Methods for Concrete Pavement on Early Strength Development in Cool Weather Condition (저온 환경에서 콘크리트 포장의 강도발현 촉진을 위한 양생방법 연구)

  • Ryu, SungWoo;Kim, JinHwan;Hong, SeungHo;Park, JeJin
    • International Journal of Highway Engineering
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    • v.19 no.3
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    • pp.11-18
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    • 2017
  • PURPOSES : This study investigates the effect on concrete pavement accordance with the curing methods in cool weather and supports the best method in the field. METHODS : Two field tests evaluated the curing methods of concrete pavement in cool weather. Firstly, five curing methods were tested, including normal curing compound, black curing compound, bubble sheet, curing mat, and curing mat covered with vinyl. Concrete maturity was compared from temperature data. Secondly, normal curing compound and curing mat with vinyl, which showed the best performance, were compared in terms of maturity and join condition index. RESULTS:From the field tests, it is an evident that curing mat with vinyl accelerated the concrete strength. Therefore, it is possible to conduct saw-cut works in cool weather, which minimizes damage on concrete at joint. CONCLUSIONS : For concrete pavement in cool weather, using curing mat with vinyl as the curing method could overcome the strength delay. Therefore, strength and durability problems on concrete at joint due to cool weather would be fewer in the future.

The Printability and Flame Retardancy for DTP Media of Polyester Fabrics Treated with Phosphate Compound (인 화합물 처리한 폴리에스테르 DTP 매체의 날염성과 방염성)

  • Kim, Soo-Chang
    • Fashion & Textile Research Journal
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    • v.6 no.5
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    • pp.667-672
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    • 2004
  • Poly(ethylene terephthalate) (PET) fabrics were treated with a silica particle and phosphate flame retardant to determine the optimum process condition of the digital textile printing(DTP) media. The treating conditions for the study were 6 conditions, from F1 to F6, in which F3, F4 and F5 were treated with mixture of both silica particle and phosphate compound in process of pad, dry and cure fixation. F6 was treated with phosphate compound only and silica particle coating successively. Xanthan gum was used to control the migration of liquid phosphate compound onto PET fabrics. The change in surface morphology of fabrics treated with silica particle and phosphate compound was observed by SEM and flame retardance was evaluated by limiting oxygen index(LOI). It was observed that F6 was the excellent flame retardance and low bleeding in printing, Collectively, the printing characteristics of silica to cyan, magenta, yellow and black ink and flame retardance of fabrics finished with phosphate compound were identified in this study.

Photorealistic Ray-traced Visualization Approach for the Interactive Biomimetic Design of Insect Compound Eyes

  • Nguyen, Tung Lam;Trung, Hieu Tran Doan;Lee, Wooseok;Lee, Hocheol
    • Current Optics and Photonics
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    • v.5 no.6
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    • pp.699-710
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    • 2021
  • In this study, we propose a biomimetic optical structure design methodology for investigating micro-optical mechanisms associated with the compound eyes of insects. With these compound eyes, insects can respond fast while maintaining a wide field of view. Also, considerable research attention has been focused on the insect compound eyes to utilize these benefits. However, their nano micro-structures are complex and challenging to demonstrate in real applications. An effectively integrated design methodology is required considering the manufacturing difficulty. We show that photorealistic ray-traced visualization is an effective method for designing the biomimetic of a micro-compound eye of an insect. We analyze the image formation mechanism and create a three-dimensional computer-aided design model. Then, a ray-trace visualization is applied to observe the optical image formation. Finally, the segmented images are stitched together to generate an image with a wide-angle; the image is assessed for quality. The high structural similarity index (SSIM) value (approximately 0.84 to 0.89) of the stitched image proves that the proposed MATLAB-based image stitching algorithm performs effectively and comparably to the commercial software. The results may be employed for the understanding, researching, and design of advanced optical systems based on biological eyes and for other industrial applications.

Analgesic, Anti-inflammatory and Antiviral Effects of Melandrin Derivatives (Melandrin유도체의 진통 소염 및 항바이러스 효과)

  • Lim, Jung-Ki;Lee, Eun-Bang;Woo, Won-Sik;Lee, Kang-Ro;Lee, Yeong-Sun;Ma, Eun-Sook
    • YAKHAK HOEJI
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    • v.38 no.3
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    • pp.345-350
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    • 1994
  • Fourteen melandrin derivatives(I-XIV) were investigated on analgesic, anti-inflammatory and antiviral activities . Compound I [N-(p-hydroxybenzoyl)-5-hydroxyanthranilic acid methvl ester], Xll [N-(2-phenoxypropionyl)-5-hydroxy anthranilic acid propyl ester and XIV [N-(2-phenoxypropionyl)-5-hydroxyanthranilic acid exhibited analgesic activity in tail pressure and Randall-Selitto method. But no anti-inflammatory activity was shown. Compound I exhibited weak antiviral activity on Herpes simplex virus type I F strain by virus-induced cytopathic effect(CPE) assay and it's selectivity index(Sl) was 8.17.

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