• 제목/요약/키워드: indeterminate

검색결과 302건 처리시간 0.025초

Application of Immunophenotyping and Heteroduplex Polymerase Chain Reaction (hPARR) for Diagnosis of Canine Lymphomas

  • Sirivisoot, Sirintra;Techangamsuwan, Somporn;Tangkawattana, Sirikachorn;Rungsipipat, Anudep
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권6호
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    • pp.2909-2916
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    • 2016
  • Background: Canine malignant lymphoma is classified into B- or T-cell origin, as in the human case. Due to differences in prognosis, a suitable method needs to be developed for lineage identification. Aims: To determine the accuracy of immunophenotypic and molecular information between three methods: immunocytochemistry (ICC), immunohistochemistry (IHC) and heteroduplex polymerase chain reaction for antigen receptor rearrangements (hPARR) in spontaneous canine lymphomas. Materials and Methods: Peripheral blood, fine needle aspiration and tissue biopsies from enlarged peripheral lymph nodes prior to treatment of 28 multicentric lymphoma patients were collected. Cytopathology and histopathology were examined and classified using the updated Kiel and WHO classifications, respectively. Anti-Pax5 and anti-CD3 antibodies as B- and T-cell markers were applied for immunophenotyping by ICC and IHC. Neoplastic lymphocytes from lymph node and white blood cell pellets from peripheral blood were evaluated by hPARR. Results: In this study, low grade B-cell lymphoma accounted for 25% (7/28), high grade B-cell lymphoma for 64.3% (18/28) and high grade T-cell lymphoma for 10.7% (3/28). According to the WHO classification, 50% of all cases were classified as diffuse large B-cell lymphoma. In addition, ICC showed concordant results with IHC; all B-cell lymphomas showed Pax5+/CD3, and all T-cell lymphomas exhibited Pax5-/CD3+. In contrast to hPARR, 12 B-cell lymphomas featured the IgH gene; seven presented the $TCR{\gamma}$ gene; five cases showed both IgH and $TCR{\gamma}$ genes, and one case were indeterminate. Three T-cell lymphomas showed the $TCR{\gamma}$ gene. The percentage agreement between hPARR and ICC/IHC was 60%. Conclusions: Immunophenotyping should not rely on a single method. ICC or IHC with hPARR should be used concurrently for immunophenotypic diagnosis in canine lymphomas.

마르크스 가치론의 이시적 단일체계 해석에 대한 몇 가지 비판적 논점 (Some Notes on the Temporal Single-System Interpretation of Marxian Value Theory)

  • 박현웅
    • 사회경제평론
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    • 제31권2호
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    • pp.105-126
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    • 2018
  • 본 논문은 마르크스 가치론의 이시적 단일체계 해석(TSSI)에 대한 두 가지 비판적 논점을 제시한다. 첫째, 일반적인 조건 하에서 마르크스주의 근본정리가 성립함을 보일 수 있는 것은 TSSI가 유일하다라는 TSSI 논자들의 주장과는 달리, 명목이윤 뿐만 아니라 실질이윤에 대한 두 개의 서로 다른 정의를 모두 고려할 경우, 마르크스주의 근본정리가 TSSI 내에서 성립하는지 여부는 결정되지 않는다. 둘째, 오키시오 정리 비판으로 제시된 클리만 (1996)의 수리모형에 대해, 오키시오 정리에서 중요한 요소인 기술변화의 비용절감 여부를 고려하지 않는다는 점이 기존 문헌에서 지적된 바 있는데, 본 논문에선 이를 수리적으로 확인하는 작업을 통해 클리만 모형의 기술변화는 비용절감적이지 않고 따라서 오키시오 정리에 대한 내재적 비판이라고 할 수 없다는 점을 보인다.

Effect of nonlinear elastic foundations on dynamic behavior of FG plates using four-unknown plate theory

  • Nebab, Mokhtar;Atmane, Hassen Ait;Bennai, Riadh;Tahar, Benabdallah
    • Earthquakes and Structures
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    • 제17권5호
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    • pp.447-462
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    • 2019
  • This present paper concerned with the analytic modelling for vibration of the functionally graded (FG) plates resting on non-variable and variable two parameter elastic foundation, based on two-dimensional elasticity using higher shear deformation theory. Our present theory has four unknown, which mean that have less than other higher order and lower theory, and we denote do not require the factor of correction like the first shear deformation theory. The indeterminate integral are introduced in the fields of displacement, it is allowed to reduce the number from five unknown to only four variables. The elastic foundations are assumed a classical model of Winkler-Pasternak with uniform distribution stiffness of the Winkler coefficient (kw), or it is with variables distribution coefficient (kw). The variable's stiffness of elastic foundation is supposed linear, parabolic and trigonometry along the length of functionally plate. The properties of the FG plates vary according to the thickness, following a simple distribution of the power law in terms of volume fractions of the constituents of the material. The equations of motions for natural frequency of the functionally graded plates resting on variables elastic foundation are derived using Hamilton principal. The government equations are resolved, with respect boundary condition for simply supported FG plate, employing Navier series solution. The extensive validation with other works found in the literature and our results are present in this work to demonstrate the efficient and accuracy of this analytic model to predict free vibration of FG plates, with and without the effect of variables elastic foundations.

한·중 서비스 무역의 수출경쟁력 비교분석 (the Comparative Analysis on Export Competitiveness for Trade in Service between Korea and China)

  • 유일선;김영환
    • 국제지역연구
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    • 제13권2호
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    • pp.643-666
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    • 2009
  • 한국과 중국 모두 세계시장에서 재화무역에서는 수출경쟁력이 있고 서비스무역에서는 경쟁력이 없으나 양국은 서비스무역 비중이 확대되고 있고 FTA논의를 통해 양국간 서비스무역은 더욱더 확대될 전망이다. 이런 배경 하에서 본 논문은 한 중간 서비스산업의 부문별 수출경쟁력을 측정하는데 그 목적이 있다. IMF의 BOP 통계수치를 이용하여 한 중 양국의 서비스 무역에 대한 수출경쟁력을 측정하기 위해 무역특화지수(TSI), 수정현시비교우위(RSCA)지수와 국제시장점유율(IMS) 및 수출증가율을 사용해서 서비스무역의 국제경쟁력을 부문별로 비교분석하였다. 그 결과 한국은 운송서비스, 금융서비스, 특허권 등 사용료, 개인 문화 오락 부문 등 4개 부문에서, 중국은 여행서비스, 통신서비스, 보험, 컴퓨터 및 정보, 기타 사업서비스 부문 등 5개 부문에서 국제경쟁력을 가지는 것으로 평가되었다. 건설부문은 비교우위를 판정할 수 없었다. 그러나 중국이 비교우위를 가지고 있는 통신서비스와 컴퓨터 및 정보서비스부문은 비교우위격차가 축소되어 서비스무역의 국제경쟁력 강화노력이 이루어지면 중국보다 경쟁력에서 우위에 설 수 있다.

Buckling behaviors of FG porous sandwich plates with metallic foam cores resting on elastic foundation

  • Abdelkader, Tamrabet;Belgacem, Mamen;Abderrahmane, Menasria;Abdelhakim, Bouhadra;Abdelouahed, Tounsi;Mofareh Hassan, Ghazwani;Ali, Alnujaie;S.R., Mahmoud
    • Structural Engineering and Mechanics
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    • 제85권3호
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    • pp.289-304
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    • 2023
  • The main objective of this paper is to study the effect of porosity on the buckling behavior of thick functionally graded sandwich plate resting on various boundary conditions under different in-plane loads. The formulation is made for a newly developed sandwich plate using a functional gradient material based on a modified power law function of symmetric and asymmetric configuration. Four different porosity distribution are considered and varied in accordance with material propriety variation in the thickness direction of the face sheets of sandwich plate, metal foam also is considered in this study on the second model of sandwich which containing metal foam core and FGM face sheets. New quasi-3D high shear deformation theory is used here for this investigate; the present kinematic model introduces only six variables with stretching effect by adopting a new indeterminate integral variable in the displacement field. The stability equations are obtained by Hamilton's principle then solved by generalized solution. The effect of Pasternak and Winkler elastic foundations also including here. the present model validated with those found in the open literature, then the impact of different parameters: porosities index, foam cells distribution, boundary conditions, elastic foundation, power law index, ratio aspect, side-to-thickness ratio and different in-plane axial loads on the variation of the buckling behavior are demonstrated.

THE IDEAL CLASS GROUP OF POLYNOMIAL OVERRINGS OF THE RING OF INTEGERS

  • Chang, Gyu Whan
    • 대한수학회지
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    • 제59권3호
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    • pp.571-594
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    • 2022
  • Let D be an integral domain with quotient field K, Pic(D) be the ideal class group of D, and X be an indeterminate. A polynomial overring of D means a subring of K[X] containing D[X]. In this paper, we study almost Dedekind domains which are polynomial overrings of a principal ideal domain D, defined by the intersection of K[X] and rank-one discrete valuation rings with quotient field K(X), and their ideal class groups. Next, let ℤ be the ring of integers, ℚ be the field of rational numbers, and 𝔊f be the set of finitely generated abelian groups (up to isomorphism). As an application, among other things, we show that there exists an overring R of ℤ[X] such that (i) R is a Bezout domain, (ii) R∩ℚ[X] is an almost Dedekind domain, (iii) Pic(R∩ℚ[X]) = $\oplus_{G{\in}G_{f}}$ G, (iv) for each G ∈ 𝔊f, there is a multiplicative subset S of ℤ such that RS ∩ ℚ[X] is a Dedekind domain with Pic(RS ∩ ℚ[X]) = G, and (v) every invertible integral ideal I of R ∩ ℚ[X] can be written uniquely as I = XnQe11···Qekk for some integer n ≥ 0, maximal ideals Qi of R∩ℚ[X], and integers ei ≠ 0. We also completely characterize the almost Dedekind polynomial overrings of ℤ containing Int(ℤ).

Visco-elastic foundation effect on buckling response of exponentially graded sandwich plates under various boundary conditions

  • Mimoun Bennedjadi;Salem Mohammed Aldosari;Abdelbaki Chikh;Abdelhakim Kaci;Abdelmoumen Anis Bousahla;Fouad Bourada;Abdeldjebbar Tounsi;Kouider Halim Benrahou;Abdelouahed Tounsi
    • Geomechanics and Engineering
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    • 제32권2호
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    • pp.159-177
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    • 2023
  • In the present work, a simple and refined shear deformation theory is used to analyze the effect of visco-elastic foundation on the buckling response of exponentially-gradient sandwich plates under various boundary conditions. The proposed theory includes indeterminate integral variables kinematic with only four generalized parameters, in which no shear correction factor is used. The visco-Pasternak's foundation is taken into account by adding the influence of damping to the usual foundation model which characterized by the linear Winkler's modulus and Pasternak's foundation modulus. The four governing equations for FGM sandwich plates are derived by employing principle of virtual work. To solve the buckling problem, Galerkin's approach is utilized for FGM sandwich plates for various boundary conditions. The analytical solutions for critical buckling loads of several types of powerly graded sandwich plates resting on visco-Pasternak foundations under various boundary conditions are presented. Some numerical results are presented to indicate the effects of inhomogeneity parameter, elastic foundation type, and damping coefficient of the foundation, on the critical buckling loads.

Theoretical buckling analysis of inhomogeneous plates under various thermal gradients and boundary conditions

  • Laid Lekouara;Belgacem Mamen;Abdelhakim Bouhadra;Abderahmane Menasria;Kouider Halim Benrahou;Abdelouahed Tounsi;Mohammed A. Al-Osta
    • Structural Engineering and Mechanics
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    • 제86권4호
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    • pp.443-459
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    • 2023
  • This study investigates the theoretical thermal buckling analyses of thick porous rectangular functionally graded (FG) plates with different geometrical boundary conditions resting on a Winkler-Pasternak elastic foundation using a new higher-order shear deformation theory (HSDT). This new theory has only four unknowns and involves indeterminate integral variables in which no shear correction factor is required. The variation of material properties across the plate's thickness is considered continuous and varied following a simple power law as a function of volume fractions of the constituents. The effect of porosity with two different types of distribution is also included. The current formulation considers the Von Karman nonlinearity, and the stability equations are developed using the virtual works principle. The thermal gradients are involved and assumed to change across the FG plate's thickness according to nonlinear, linear, and uniform distributions. The accuracy of the newly proposed theory has been validated by comparing the present results with the results obtained from the previously published theories. The effects of porosity, boundary conditions, foundation parameters, power index, plate aspect ratio, and side-to-thickness ratio on the critical buckling temperature are studied and discussed in detail.

일정체적 정적 최강아치 (Strongest Static Arches with Constant Volume)

  • 이병구;오상진;이태은
    • 대한토목학회논문집
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    • 제29권5A호
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    • pp.477-486
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    • 2009
  • 이 논문은 정다각형 중실 변단면을 갖는 정적 최강아치에 관한 연구이다. 아치의 지간길이와 체적은 정다각형 단면깊이의 형상함수에 상관없이 항상 일정하다. 아치에 정적 연직 집중하중과 수평 집중하중이 작용하는 경우에 단면에 발생하는 최대 수직응력을 산정하였다. 산정된 최대 수직응력이 최소가 되는 정적 최강아치의 변단면 형상, 즉 일정체적 변단면 아치의 단면비를 산정하였다. 부정정 아치의 부정정력을 구하기 위하여 최소일의 원리를 이용하였다. 일련의 수치해석 예를 통하여 정적 최강아치의 단면비를 표 및 그림에 나타내었다. 이 연구의 결과는 아치구조의 최소중량 설계에 매우 유용한 자료를 제공 할 수 있다.

The effect of visco-Pasternak foundation on the free vibration behavior of exponentially graded sandwich plates with various boundary conditions

  • Fatima, Bounouara;Salem Mohammed, Aldosari;Abdelbaki, Chikh;Abdelhakim, Kaci;Abdelmoumen Anis, Bousahla;Fouad, Bourada;Abdelouahed, Tounsi;Kouider Halim, Benrahou;Hind, Albalawi;Abdeldjebbar, Tounsi
    • Steel and Composite Structures
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    • 제46권3호
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    • pp.367-383
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    • 2023
  • In this investigation, an improved integral trigonometric shear deformation theory is employed to examine the vibrational behavior of the functionally graded (FG) sandwich plates resting on visco-Pasternak foundations. The studied structure is modelled with only four unknowns' variables displacements functions. The simplicity of the developed model being in the reduced number of variables which was made with the help of the use of the indeterminate integral in the formulation. The current kinematic takes into consideration the shear deformation effect and does not require any shear correction factors as used in the first shear deformation theory. The equations of motion are determined from Hamilton's principle with including the effect of the reaction of the visco-Pasternak's foundation. A Galerkin technique is proposed to solve the differentials governing equations, which enables one to obtain the semi-analytical solutions of natural frequencies for various clamped and simply supported FG sandwich plates resting on visco-Pasternak foundations. The validity of proposed model is checked with others solutions found in the literature. Parametric studies are performed to illustrate the impact of various parameters as plate dimension, layer thickness ratio, inhomogeneity index, damping coefficient, vibrational mode and elastic foundation on the vibrational behavior of the FG sandwich plates.