• 제목/요약/키워드: independent reading

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섬에서 에코톤으로-경계중첩지대로서의 자연인식과 생태비평적 함의 (From Island to Ecotone: Nature Recognition as Boundary Crossed and Ecocritical Implication)

  • 신두호
    • 영어영문학
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    • 제57권2호
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    • pp.237-264
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    • 2011
  • Based on its geophysical feature, the island has long been recognized as a separate and self-sustaining space independent of neighboring continent or other islands. Literary tradition has used the island as a metaphor for a utopian alternative to mundane human society with its various kinds of wrongdoings. Recent nature writings have taken up this island metaphor to emphasize the wholeness of the ecosystem in specifically designated natural community or landscapes such as national parks or wilderness preservation areas. Human-nature relations as border-divided area is also recognized as the island. Modern island biogeography, however, has disproved such a concept of islands as autonomous, revealing the contrasting fact that the richness of species on an undisturbed island is determined largely by species immigration from and emigration to a source of colonists. This scientific finding has posited the island as the interconnected nature, but the public and metaphoric use of it still resorts to the old concept of it as isolated and autonomous nature, because this image has been ingrained deeply in our consciousness and culture. Considering the negative consequences from the recognition of nature and nature-humans as isolated space, we need a new nature metaphor that embodies interconnectedness in nature and of human-nature relations. Such feature of interconnectedness is best embedded in the concept of ecotone. Some ecotones are created and maintained through human participation in nature, and this human induced nature of ecotone denotes the possibilities of a constructive relation between them. The substitution of the island with the ecotone as the concept of nature and the image of human-nature relations is expected to correct ecocritical practices of reading of nature writing, which has been predominantly interpreted within the orientation of nature itself and nature-human relations as an isolated and self-autonomous island. Adopting the ecotone in literary study enables ecocriticism to dig out cultural elements embedded in nature writing and reveal socio-political, ideological factors hidden behind the writers' portrayal of nature as islands.

Comparing Complications of Biologic and Synthetic Mesh in Breast Reconstruction: A Systematic Review and Network Meta-Analysis

  • Young-Soo Choi;Hi-Jin You;Tae-Yul Lee;Deok-Woo Kim
    • Archives of Plastic Surgery
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    • 제50권1호
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    • pp.3-9
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    • 2023
  • Background In breast reconstruction, synthetic meshes are frequently used to replace acellular dermal matrix (ADM), since ADM is expensive and often leads to complications. However, there is limited evidence that compares the types of substitutes. This study aimed to compare complications between materials via a network meta-analysis. Methods We systematically reviewed studies reporting any type of complication from 2010 to 2021. The primary outcomes were the proportion of infection, seroma, major complications, or contracture. We classified the intervention into four categories: ADM, absorbable mesh, nonabsorbable mesh, and nothing used. We then performed a network meta-analysis between these categories and estimated the odds ratio with random-effect models. Results Of 603 searched studies through the PubMed, MEDLINE, and Embase databases, following their review by two independent reviewers, 61 studies were included for full-text reading, of which 17 studies were finally included. There was a low risk of bias in the included studies, but only an indirect comparison between absorbable and non-absorbable mesh was possible. Infection was more frequent in ADM but not in the two synthetic mesh groups, namely the absorbable or nonabsorbable types, compared with the nonmesh group. The proportion of seroma in the synthetic mesh group was lower (odds ratio was 0.2 for the absorbable and 0.1 for the nonabsorbable mesh group) than in the ADM group. Proportions of major complications and contractures did not significantly differ between groups. Conclusion Compared with ADM, synthetic meshes have low infection and seroma rates. However, more studies concerning aesthetic outcomes and direct comparisons are needed.

어린이·청소년 대상 성교육 도서의 출판과 활용에 관한 탐색적 연구 (An Exploratory Study of the Publication and Use of Sexuality Education Books for Youth)

  • 임여주
    • 한국비블리아학회지
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    • 제34권2호
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    • pp.205-232
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    • 2023
  • 본 연구는 어린이·청소년을 대상으로 하는 성교육 도서의 출판과 활용 현황을 점검하고 앞으로 성교육 도서가 어린이·청소년의 성교육에 효과적으로 활용될 가능성을 가늠해 보는 탐색적 연구이다. 이를 위해 어린이·청소년 독자가 성교육 도서에 접근하게 하는 데 중요한 역할을 하는 출판 편집자, 성교육 전문가, 공공도서관 사서와의 심층 면담을 진행하고, 성교육 도서에 관한 이들의 경험과 시각을 폭넓게 분석하였다. 연구 참여자들에 의하면 성교육 도서는 양육자가 어린이·청소년에게 직접 성교육을 실시하기 어려워할 때 쉽게 찾아 건네는 매체이며 성교육 현장에서 활용되는 교육 자료이기도 하다. 연구 참여자들은 현재 한국에 출판된 성교육 도서 중 다수가 사춘기의 신체 변화를 다루는 '몸 교육'에만 집중하고 있으며, 여전히 성평등하지 않은 관점을 강조하는 등 그 주제와 시각에 한계가 있다고 지적하였다. 이들은 성교육 도서가 키워드 중심의 단순한 정보 전달 매체이기보다, 인간 삶에 대한 포괄적인 시각을 바탕으로 주체적인 성을 배우는 교육의 장이기를 바랐다. 본 연구에서 제시하는 가이드라인은 도서관에서 성교육 도서를 수서할 때 참고할 수 있는 좋은 지침이 될 것이다.

Bone Suppression on Chest Radiographs for Pulmonary Nodule Detection: Comparison between a Generative Adversarial Network and Dual-Energy Subtraction

  • Kyungsoo Bae;Dong Yul Oh;Il Dong Yun;Kyung Nyeo Jeon
    • Korean Journal of Radiology
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    • 제23권1호
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    • pp.139-149
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    • 2022
  • Objective: To compare the effects of bone suppression imaging using deep learning (BSp-DL) based on a generative adversarial network (GAN) and bone subtraction imaging using a dual energy technique (BSt-DE) on radiologists' performance for pulmonary nodule detection on chest radiographs (CXRs). Materials and Methods: A total of 111 adults, including 49 patients with 83 pulmonary nodules, who underwent both CXR using the dual energy technique and chest CT, were enrolled. Using CT as a reference, two independent radiologists evaluated CXR images for the presence or absence of pulmonary nodules in three reading sessions (standard CXR, BSt-DE CXR, and BSp-DL CXR). Person-wise and nodule-wise performances were assessed using receiver-operating characteristic (ROC) and alternative free-response ROC (AFROC) curve analyses, respectively. Subgroup analyses based on nodule size, location, and the presence of overlapping bones were performed. Results: BSt-DE with an area under the AFROC curve (AUAFROC) of 0.996 and 0.976 for readers 1 and 2, respectively, and BSp-DL with AUAFROC of 0.981 and 0.958, respectively, showed better nodule-wise performance than standard CXR (AUAFROC of 0.907 and 0.808, respectively; p ≤ 0.005). In the person-wise analysis, BSp-DL with an area under the ROC curve (AUROC) of 0.984 and 0.931 for readers 1 and 2, respectively, showed better performance than standard CXR (AUROC of 0.915 and 0.798, respectively; p ≤ 0.011) and comparable performance to BSt-DE (AUROC of 0.988 and 0.974; p ≥ 0.064). BSt-DE and BSp-DL were superior to standard CXR for detecting nodules overlapping with bones (p < 0.017) or in the upper/middle lung zone (p < 0.017). BSt-DE was superior (p < 0.017) to BSp-DL in detecting peripheral and sub-centimeter nodules. Conclusion: BSp-DL (GAN-based bone suppression) showed comparable performance to BSt-DE and can improve radiologists' performance in detecting pulmonary nodules on CXRs. Nevertheless, for better delineation of small and peripheral nodules, further technical improvements are required.

광복이후 한국 공공도서관사 연구 -일제하 공공도서관제도의 영향을 중심으로- (A Study of the History of Korean Public Library after the Korean Liberation Day - An Emphasis on the influence of public Libraries System under the Japanese Imperialism-)

  • 김포옥
    • 한국문헌정보학회지
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    • 제20권
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    • pp.65-125
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    • 1991
  • The study has tried to analize and appraise how did public library system under the Japanese imperialism affect the establishment and managemant of Korean public libraries. To achieve the purpose of the above-mentioned study, the contents of $\ulcorner$Japanese library statute$\lrcorner$ under Japanese imperialism and the current $\ulcorner$Korean library law$\lrcorner$ have been mutually compared, at the same time, the vestiage of Japanese imperialism in view of the establishment, personnel administration and reading systems have been concretely investigated, analyzed and compared. The conclusions obtained from the above are as followings. 1. In those days of the Korean Liberation, the situation of Korean public libraries was such as it under the Japanese rule and so, their names were only changed. However, as a part of its independent activities, the national library have once carried out the various programs such as the training of professional librarians, the establishment of the new classification schedule and the chief Librarian and deputy Librarian from the professional librarians in the office regulations, and they were well worth being the good examples for today's Korean library circle. Though the Goverment of the Republic of Korea had been formally established, the situation of the library circle was very dull owing to the Korean war for a long time. In 1963, $\ulcorner$The Korean library law$\lrcorner$ was promulgated, but the establishment of public libraries did not give satisfactory results because of the institutional fragility. In the 1980's the importance of library was embossed from the viewpoint of life-long education and the number of libraries was increased. However, there were still the remaining vestiges of Japanese library system in the practical library services. 2. After the Korean Liberation, the influnces of public library system under the Japanese imperialism showed in the office regulation of national library and the Korea library Law were also in the legal mechanism. In particular, the regulations of $\ulcorner$The staff-member of public library$\lrcorner$ and $\ulcorner$Admission fee of public library$\lrcorner$ including the chief librarian have referred to the library system under the Japanese imperialism since the liberation day to date. 3. At that time of the Korean Liberation, the U.S.Military Government Office had decided that the public library administration should be attached to the administration of local and internal affairs in accordance with the Japanese administative system. As a result, the public libraries had been forced to be indirectly affected by public library system under the Japanese imperialism for twenty years since the Liberation. 4. Since the Liberation, the personnel adminstration of public library has been so far on the steps of model under the Japanese imperialism. As the result of the field survey, the position standards of local chief librarians, non-professional character, the extra post system and the preponderant appointment of non-professional offices have analyzed by the influence of Public library system under the Japanese imperialism. Therefore, the Government authorities-concerned must readjust the standards of qualification and the divided duties corresponding to the position of public library staff members and to stipulate expressly in the revised library law. In addition, the regulation of the admission fee should be also actively detected for the free adminssion of library users. 5. Since the Liberation Day, the reading methods of public library have been so far similar to reading method under the Japaness imperialism. For example, the admission fee levied, the complicated procedures of using books including entrance and exit of a library, no-admission system, the limited lending books, the deposit system of outdoor lending books and the surety liable jointly and severally are originally caused by bureaucracy of under the Japanese imperialism. Therefore, the public libraries should make an offer space and opportunities which can enjoy freedom to the gull in future. The procedures and standards of library users will be simplified, if possible. As the above-mentioned, the actual conditions of Korean public libraries have been examined and analyzed. As the result of it, there are still the remaining vestiges of public library system under the Japanese imperialism in the establishment and management of the nation-wide public libraries. Such the remnants are an obstacle to the democratic development of public libraries and so, the authorities-concerned should take the proper-measures as soon as possible.

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자립적인 노후생활을 위한 노인용 코하우징 교수·학습 과정안 개발 및 적용 - 고등학교 기술·가정을 중심으로 - (Development and Application of the Teaching·Learning Process Plan of Senior Cohousing for Independent later Life - Focusing on high school Technology·Home Economics -)

  • 나지명;조재순
    • 한국가정과교육학회지
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    • 제28권3호
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    • pp.1-16
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    • 2016
  • 이 연구는 고등학교 기술 가정에 적용하여 자립적인 노후생활을 실천할 수 있는 역량을 기르기 위한 노인용 코하우징 교수 학습과정안과 학습자료를 개발하여 실행한 후, 학생평가와 교사평가를 통해 이 교수 학습과정안의 수업효과를 알아보는 것을 목적으로 하였다. 이를 위해 ADDIE 교수 설계 모형에 따라 분석, 설계, 개발, 실행, 평가 단계로 연구를 진행하였다. 분석 단계에서는 교육과정, 교과서, 선행연구를 분석하여 총괄학습 목표와 차시별 수업주제를 정하였고, 설계 단계에서는 교수 학습 내용을 재구성하여 수업 진행과정을 설계하였고, 개발 단계에서는 학습자 중심의 수업 방법을 적용하여 총 5차시분의 노인용 코하우징 교수 학습과정안과 다양한 교수 학습 자료(학습활동지 28개, 과제활동지 2개, 교사 읽기자료 26개, 동영상자료 10편, PPT 4편 등)와 수업평가용 질문지를 개발하였다. 실행은 2015. 8. 17~9. 3까지 3주간 제주도 인문계 P고등학교 1학년 6학급 전체 학생(150명)을 대상으로 교과담당교사가 실시하였고, 평가는 5차시 수업 종료 직후 설문지를 통해 노인용 코하우징 수업에 대한 학생의 평가와 수업 실행 교사의 수업 기록물과 연구자와의 면담 내용, 연구자의 참관기록을 바탕으로 종합하였다. 연구 결과, 수업 전반에 대한 학생의 참여도, 학습주제 이해, 학습 자료와 학습활동의 적정성, 미래 생활에의 도움 예상 정도 등의 평가가 고르게 높았으며, 노인과 노후준비의 필요성에 대한 이해 강화, 노인용 코하우징에 대한 이해 형성, 고령친화산업과 노인 관련 직업에 대한 관심을 향상시켰다. 학습자 중심의 수업활동 중 특히 노인용 코하우징 만들기 실습활동과 사례조사 발표가 효과적이었다. 학생과 교사의 평가가 높았던 마을 만들기 모둠활동의 결과물에는 수업이 실행된 제주도의 특색인 돌하르방, 해수욕장, 오름, 풍력발전 등이 표현되어 이 수업을 통해 거주하고 있는 지역사회에 관심을 갖고, 자긍심을 높일 수 있는 가능성을 엿볼 수 있었다. 이러한 연구결과를 바탕으로 이 연구에서 개발한 교수 학습 과정안은 청소년이 앞으로 살아갈 고령사회를 인식하여 나뿐만 아니라 부모님, 조부모님의 자립적인 노후생활을 위한 준비에 관심을 갖고, 이웃과 함께 더불어 살아가는 건강하고 행복한 가정생활 문화를 주도할 수 있는 실천적 역량을 기르는 데 도움이 되는 수업이라고 볼 수 있겠다.

폴리오바이러스의 분자생물학 (Molecular Miology of the Poliovirus)

  • 최원상
    • 생명과학회지
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    • 제7권4호
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    • pp.392-401
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    • 1997
  • 폴리오바이러스는 바이러스들 중에서도 특히 커기가 작은 바이러스로서 피막(coat)을 둘러싸는 막(envelop) 이 없다. 폴리오바이러스는 (+) 가닥의 단일 RNA 게놈을 갖는데 이는 한 개의 해독판 (open reading frame)을 이용하여 다단백전구체를 만든 후 바이러스 자체의 단백질분해효소에 의해 스스로 잘라져서 궁극적으로느 특이한 기능을 갖는 여러개의 단백질이 된다. P1 다단백질전구체로부터 만들어지는 단백질들은 바이러스의 피막을 구성하는 성분이다. 단백질분해효소인 2A에 의한 최초의 절단은 구조단백질 P1 전구체와 구조단백질이 아닌 P2-P3간을 분리시켜준다. 단백질분해효소 2A는 진핵세포 판독개시인자(translation initiation factor) 4F의 한 subunit인 숙주단백질 p220의 절단에 간접으로 참여한다. 이 단백질의 절단은 캡(cap)에 의존하는 숙주세포의 대부분의 판독을 차단하게 되며 이는 판독에 사용되는 숙주세포의 모든 기구들을 캡에 의존하지 않는 폴리오바이러스 NA 특유의 판독을 위해 전적으로 사용할 수 있게 해준다. 2B, 2C, 2BC 단백질의 기능에 대해서는 많이 알려져 있지 않다. 2B, 2C, 2BC와 3CD 단백질들은 바이러스로 인해 만들어지는 소낭(vesicle)의 복제복합체에 함유되어 있으므로 바이러스의 RNA 복제시 중요한 역할을 함을 암시해준다. 새로이 만들어진 모든 바이러스 RNA는 VPg와 공유결합으로 연결되어 있다. VPg는 3AB로부터 만들어진 아미노산 22개 짜리의 폴리펩타이드이다. 3C와 3CD는 단백질분해소로 다단백질 전구체의 대부분의 절단부위를 잘라준다. 3C단백질은 숙주의 전사인자를 불활성화 시킴으로써 RNA polymer II와 III에 의한 전사를 저해한다. 3D는 RNA의존선RNA 중합효소이다. 폴리오바이러스는 (+)가닥 RNA 바이러스의 일반적인 복제양식을 따른다. 즉 (+) 가닥 RNA는 이와 상보적인 (-)가닥 RNA로 전사되고 이는 다시 (+)가닥 RNA의 합성을 위한 주형으로 사용된다. 폴리오바이러스의 RNA 합성은 세포내막에서 일어나는 데 RNA 복제에 요구되는 주형 RNA와 이때 필요한 단백질들이 어떤 방법으로 세포내막에서 모일 수 있는지는 아직 밝혀진 것이 적다. 바이러스입자의 형성은 세포막의 RNA 복제가 들어가는 데 피막단백질이 (+)가닥 RNA을 인식하는 표지 즉 packaging singal에 대해서는 거의 알려져 있지 않다. 폴리오바이러스 감염 후 첫 바이러스입자가 만들어지기 까는 약 6시간이 소요된다.

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Molecular Cloning and Characterization of a New cDNA Encoding Hyoscyamine 6β-hydroxylase from Roots of Anisodus acutangulus

  • Kai, Guoyin;Chen, Junfeng;Li, Li;Zhou, Genyu;Zhou, Limin;Zhang, Lei;Chen, Yuhui;Zhao, Linxia
    • BMB Reports
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    • 제40권5호
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    • pp.715-722
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    • 2007
  • A new full-length cDNA encoding hyoscyamine $6\beta$-hydroxylase (designated as aah6h, GenBank Accession No. EF187826), which catalyzes the last committed step in the scopolamine biosynthetic pathway, was isolated from young roots of Anisodus acutangulus by rapid amplification of cDNA ends (RACE) for the first time. The full-length cDNA of aah6h was 1380 bp and contained a 1035 bp open reading frame (ORF) encoding a deduced protein of 344 amino acid residues. The deduced protein had an isoelectric point (pI) of 5.09 and a calculated molecular mass of about 38.7 kDa. Sequence analyses showed that AaH6H had high homology with other H6Hs isolated from some scopolamine-producing plants such as Hyoscyamus niger, Datura metel and Atropa belladonna etc. Bioinformatics analyses results indicated AaH6H belongs to 2-oxoglutarate-dependent dioxygenase superfamily. Phylogenetic tree analysis showed that AaH6H had closest relationship with H6H from A. tanguticus. Southern hybridization analysis of the genomic DNA revealed that aah6h belonged to a multi-copy gene family. Tissue expression pattern analysis firstly founded that aah6h expressed in all the tested tissues including roots, stems and leaves and indicated that aah6h was a constitutive-expression gene, which was the first reported tissue-independent h6h gene compared to other known h6h genes.

Isolation and Expression Analysis of a GDSL-like Lipase Gene from Brassica napus L.

  • Ling, Hua;Zhao, Jingya;Zuo, Kaijing;Qiu, Chengxiang;Yao, Hongyan;Qin, Jie;Sun, Xiaofen;Tang, Kexuan
    • BMB Reports
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    • 제39권3호
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    • pp.297-303
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    • 2006
  • As lipolytic enzymes, GDSL lipases play an important role in plant growth and development. In order to identify their functions and roles, the full-length cDNA of a GDSL lipase gene, designated BnLIP2, was isolated from Brassica napus L. BnLIP2 was 1,300 bp long, with 1,122 bp open reading frame (ORF) encoding 373 amino acid residues. Sequence analysis indicated that BnLIP2 belonged to GDSL family. Southern blot analysis indicated that BnLIP2 belonged to a small gene family in rapeseed genome. RT-PCR analysis revealed that BnLIP2 was a tissue-specific expressing gene during reproductive growth and strongly expressed during seed germination. BnLIP2 expression could not be detected until three days after germination, and it subsequently became stronger. The transcript of this gene was deficient in root of seedlings growing at different stages. When juvenile seedlings were treated by methyl jasmonate (MeJ), salicylic acid (SA) and naphthalene acetic acid (NAA), BnLIP2 expression could not be induced in root. Our study implicates that BnLIP2 probably plays an important role in rapeseed germination, morphogenesis, flowering, but independent of root growth and development.

글쓰기 수업에서 음악과의 융합 가능성에 대한 탐색적 연구 (Exploratory Study on the Possibilities of Convergence with Music in Writing Classes)

  • 이란
    • 한국콘텐츠학회논문지
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    • 제20권8호
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    • pp.88-100
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    • 2020
  • 본 연구는 오늘날 대학의 복합양식적 글쓰기 교양 교육의 필요성과 가능성을 조명한 문헌연구 성격의 탐색적 연구이다. 연구 목적은 음악과 글쓰기를 결합시켜 교육에 활용한 기존 연구들을 분석하여 그 교육적 함축을 찾아보고 Meyrowitz의 미디어를 바라보는 세 관점에 따라 그 연구들의 개념과 결과들을 종합 정리하여 글쓰기 교육의 입장에서 음악과의 융합 형태적 가능성을 제시하는 것이다. 기존 연구들은 크게 네 범주로 나누어 볼 수 있었다. 첫째는 범교과적 글쓰기의 관점, 둘째는 치유적 효과의 관점, 셋째는 글쓰기를 위한 사고 자료적 관점, 마지막은 신문식성의 관점이다. 이 개념들을 Meyrowitz의 관점으로 정리해 볼 때, 먼저는 환경으로서 음악을 활용하는 것인데 글쓰기 교육의 배경 음악으로 활용하여 음악이 가진 감성, 회상, 치유적 효과를 간접적으로 활용하는 것이다. 두 번째는 글쓰기 도구로서 음악을 활용하는 것인데 현재 교육 현장에서 가장 보편적으로 활용되는 양식이다. 음악을 일종의 읽기자료로 활용하여 정의적, 인지적, 전략적 영역 모두에서 효과를 얻을 수 있다. 셋째는 음악과 서사의 융·복합적 글쓰기로 제시하였다. 음악이 독자적 언어 매체로서 서사 매체와 상호작용하면서 의미를 구성하는 방식으로 글쓰기를 시도한다. 이 세 가지 차원은 관점은 서로 다르지만 동시에 일어나는 교육 작용일 수 있으며 서로가 결합된 형태로 진행될 수도 있다. 본고는 이러한 수업을 위해서는 글쓰기 교수자에게 음악적 역량이나 음악과의 융합 글쓰기에 대한 전문적인 관심과 노력이 필요하며 팀티칭도 하나의 대안이 될 수 있음을 강조하였다.