• Toxicological Research
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• 제11권1호
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• pp.103-108
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• 1995

Rat renal proximal tubule suspension was prepared from adult male Sprague Dawley rat (250-300g) by mechanical (non-enzymatical) method and evaluated as a pontential model for mechanistic studies and early screening of nephrotoxicity, using anionic antibiotics (cephaloridine). Cephaloridine (CPL) produced an increase in LDH release into media. This release results from decrease a proximal tubule cell viability and subsequently increase the permeability of cell viability and subsequently increase the permeability of cell membrane. Since loss of intracellular potassium and ATP into media is the sign of disruption of cell membrane, especially basolateral membrane (BLM), CPL induced proximal tubule cell compromise also appear be associated with BLM, maybe $Na^+-K^+$ ATPase. Also seen was significant depression in brush border membrane (BBM) ALP activity and no significantly increase in BBM GGT activities. The inhibition of typical anion, PAH accumulation (especially, CPL 5 mM) and cation, TEA (especially, 4hours incubation) were seen dose dependently. This is because of CPL accumulation in renal proximal tubule and increase of cytotoxicity.

• 한국환경과학회지
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• 제4권3호
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• pp.259-267
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• 1995

This study was conducted to evaluate the effects of pressure and dissolved oxygen concentration on the activated slut비e and to determine the optimum depth of deep shaft process. Some results from this study were summarized as follows. 1. It is considered that low sludge product in the activated sludge system maintaining high dissolved oxygen concentration is attributed to the increase of endogeneous respiration rate caused by the increase of aerobic zone in the sludge floe. 2. The increase of dissolved oxygen concentration does not affect to the increase of organic removal efficiency greatly and therefore the limiting factor is the substrate transfer into the inner part of floe. 3. The yield coefficient, Y is decreased in proportion to the increase of oxygen concentration. In this study, Y values arre ranged from 0.70 to 0.41 according to the variation of dissolved oxygen concentration from 18.0mg/$\ell$ to 258 mg/$\ell$. 4. The optimum depth of deep shaft process should be determined within the limits of non-toxicity to the microorganism and it is about loom in this study.

• 무역상무연구
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• 제74권
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• pp.105-124
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• 2017

This study aims to present the effects of the introduction of the Compliance Program in Korea on real trade and its implication by empirical analysis. First, through regression analysis based on the data of the amount of permitted export by CP items (HSK10 units) during the period of 2010-2016 in Korea, it is revealed that the increase in export license of CP enterprises has a relatively greater effect on the increase in total imports by item. Second, since the introduction of the rating system under the optional CP in 2014, the increase in export licenses of CP companies has had a greater impact on the total export growth by items than before. Also, it is analyzed that the increase of export permission of CP companies has a relatively less effect on the increase of total imports by item than that of total exports. The results of this empirical analysis show that CP has a positive effect on exports and imports, but it needs to be supplemented in terms of efficiency.

• 감성과학
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• 제5권3호
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• pp.67-74
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• 2002

Testing device was newly designed and built to measure the dynamic contact angle. The measurement was made using microscope interfaced with computerized image analysis system while the dynamic condition being controled using Instron. As specimens for the experiment, two different types of fibers, i.e., hydrophilic and hydrophobic, were prepared. In case of hydrophilic fiber, the increase of twist level gave the increase of contact angle. However, in hydrophobic yarn the increase of twist level gave the decrease of contact angle. When saline was used as a telling liquid, the increase of the concentration gave the increase of contact angle. The results rationalized clearly on the basis of known concepts could be used in designing fabric structure for the improvement of comport performance.

• Journal of Microbiology and Biotechnology
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• 제17권3호
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• pp.520-523
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• 2007

Edible films of gelatin and com zein were prepared by incorporating nisin to the film-forming solutions. Com zein film with nisin of 12,000 IU/ml had an increase of 11.6 MPa in tensile strength compared with the control, whereas gelatin film had a slight increase with the increase of nisin concentration added. Water vapor permeability for both com zein and gelatin films decreased with the increase of nisin concentration, thus providing a better barrier against water. Antimicrobial activity against Listeria monocytogenes increased with the increase of nisin concentration, resulting in 1.4 log cycle reduction for com zein film and 0.6 log cycle reduction for gelatin film at 12,000 IU/ml. These results suggest that incorporation of nisin into com zein and gelatin films improve the physical properties of the films as well as antimicrobial activity against pathogenic bacteria during storage, resulting in extension of the shelf life of food products by providing with antimicrobial edible packaging films.

• 대한약리학회지
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• 제19권1호
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• pp.115-122
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• 1983

The influences of diazepam and naloxone on the increase of plasma corticosterone level induced by morphine, pentazocine, ACTH, or picrotoxin were investigated in male mice. The results obtained were summarized as follows: 1) The increase induced by morphine or pentazocine of plasma corticosterone level was not affected by naloxone pretreatment but markedly suppressed by diazepam pretreatment. 2) The increase induced by ACTH of plasma corticosterone level was not affected by diazepam or naloxone pretreatment. 3) The picrotoxin markedly increased plasma corticosterone level, and the inceease was not affected by diazepam or naloxone pretreatment. This above results suggest that the increase induced by opioids of plasma corticosterone level seems to be rather related with other than opiate- or GABArerecptor.

• Geomechanics and Engineering
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• 제16권1호
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• pp.97-104
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• 2018

The finite difference software Flac3D is used to study the influence of tunnel burial depth, tunnel diameter and lateral pressure coefficient of original rock stress on the stress and deformation of tunnel surrounding rock under sandstone condition. The results show that the maximum shear stress, the radius of the plastic zone and the maximum displacement in the surrounding rock increase with the increase of the diameter of the tunnel. When the lateral pressure coefficient is 1, it is most favorable for surrounding rock and lining structure, with the increase or decrease of lateral pressure coefficient, the maximum principal stress, surrounding displacement and plastic zone range of surrounding rock and lining show a sharp increase trend, the plastic zone on the lining increases with the increase of buried depth.

• Journal of Plant Biology
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• 제34권3호
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• pp.191-199
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• 1991

This study has been conducted to investigate the developmental changes of cambial initials and their derivatives in relation to the growing girth of tree in Diosypros kaki and Firmiana simplex. In D. Kaki and F. simplex with typical storeyed cambium, increase in the girth of camium occurred by radial anticlinal division in general, however occasionally the increase was companied by pseudotransverse division. The length of fusiform initials, vessel member, and sieve tube member remained relatively constant throughout the secondary growth but that of fiber showed general tendancy to increase with growing girth of tree. During the girth increase of tree, height and number of ray remained constant in D. kaki, however in F. simplex, height of ray markedly decreased while the number of ray per unit area more or less increased. The secondary ray was originated from the segmentation or division of the side or end of fusiform initials.

• 대한치과교정학회지
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• 제17권1호
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• pp.85-91
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• 1987

The aim of this study was to clarify whether bonding/debonding procedure will affect the occurance of enamel crack. The frequency of enamel crack was compared between before-bonding and after-debonding on 200 human extracted teeth. Each facial surface of the tooth was divided in 9 fragments. A presence of crack, which was classified by its direction as vertical, horizontal and oblique crack, was surveyed in each fragment. Number of all cracks in facial surface was 1355 at before-bonding, and 1605 at after-debonding, so it revealed significant increase rate of $18.5\%$, but compared by fragment, cracks were significantly Increased in OC, OD, CC and GC fragments. All kinds of cracks were significantly increased, especially increase rate of oblique crack reached $54.9\%$. The increase rate of cracks was not superior at any fragment or region, but some evidence was seen in CC fragment. Judging from the above, increase of crack is unavoidable with bonding/debonding procedures.

• International Journal of Fluid Machinery and Systems
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• 제9권3호
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• pp.205-212
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• 2016

The performance of a prototype pump converted from that of its model pump shows an increase in efficiency brought about by a decrease in friction loss. As the friction force working on impeller blades causes partial peripheral motion on the outlet flow from the impeller, the increase in the prototype's efficiency causes also a decrease in its input power. This paper discusses results of analyses on the behavior of the theoretical head or input power of a prototype pump. The equation of friction-drag coefficient for a flat plate was applied for the analysis of hydraulic loss in impeller blade passages. It was revealed that the friction-drag of a flat plate could be, to a certain degree, substituted for the friction drag of impeller blades, i.e. as a means for analyzing the relationship between a prototype pump's efficiency increase and input power decrease.