• 국제초고층학회논문집
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• 제2권3호
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• pp.179-192
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• 2013

The lack of systematic validation for the design process supporting tall buildings motivated the authors' research groups and their collaborators to found the Chicago Full-Scale Monitoring Program over a decade ago. This project has allowed the sustained in-situ observation of a collection of tall buildings now spanning worldwide. This paper overviews this program and the lessons learned in the process, ranging from appropriate technologies for response measurements to the factors influencing accurate prediction of dynamic properties all the way to how these properties then influence the prediction of response using wind tunnel testing and whether this response does indeed correlate with in-situ observations. Through this paper, these wide ranging subjects are addressed in a manner that demonstrates the importance of continued promotion and expansion of full-scale monitoring efforts and the ways in which these programs can provide true value-added to building owners and managers.

• 지질공학
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• 제11권1호
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• pp.25-35
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• 2001

충청남도 홍성지역의 부지응답특성 평가를 위한 연구를 수행하기 위하여 다운홀 및 SASW 기법 등의 현장시험과 공진주/비틂전단시험 등 실내시험을 수행하였다. 이를 바탕으로 홍성지역의 부지특성을 평가하고 지반응답해석을 실시하였다. 홍성지역 현장은 지반은, 상부토층 30m의 평균전단파 속도가 209m/s로 SD 지반으로 결정되었고 응답해석결과 국내 기준과 잘 일치되는 부분도 있었으나, 구조물 주기에 따른 응답스펙트롬의 특정 주기에서 국내 기준보다 크게 증폭되는 현상도 발견되었다.

• Clinical and Experimental Pediatrics
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• 제53권3호
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• pp.273-285
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• 2010

Completion of the human genome project has allowed a deeper understanding of molecular pathophysiology and has provided invaluable genomic information for the diagnosis of genetic disorders. Advent of new technologies has lead to an explosion in genetic testing. However, this overwhelming stream of genetic information often misleads physicians and patients into a misguided faith in the power of genetic testing. Moreover, genetic testing raises a number of ethical, legal, and social issues. Diagnostic genetic tests can be divided into three primary but overlapping categories: cytogenetic studies (including routine karyotyping, high-resolution karyotyping, and fluorescent in situ hybridization studies), biochemical tests, and DNA-based diagnostic tests. DNA-based testing has grown rapidly over the past decade and includes preandpostnatal testing for the diagnosis of genetic diseases, testing for carriers of genetic diseases, genetic testing for susceptibility to common non-genetic diseases, and screening for common genetic diseases in a particular population. Theoretically, once a gene's structure, function, and association with a disease are well established, the clinical application of genetic testing should be feasible. However, for routine applications in a clinical setting, such tests must satisfy a number of criteria. These criteria include an acceptable degree of clinical and analytical validity, support of a quality assurance program, possibility of modifying the course of the diagnosed disease with treatment, inclusion of pre-and postnatal genetic counseling, and determination of whether the proposed test satisfies cost-benefit criteria and should replace or complement traditional tests. In the near future, the application of genetic testing to common diseases is expected to expand and will likely be extended to include individual pharmacogenetic assessments.

• Geomechanics and Engineering
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• 제23권4호
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• pp.381-392
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• 2020

The difficulties, challenges and limitations faced in standard pressuremeter testing in the measurement of low soil deformations led a number of researchers to think about the possible modification of the equipment, and especially the replacement of the volumeter by a Hall Effect sensor. This article is a major contribution in this direction. It makes an attempt to detail the design, manufacture and operation of the new equipment. The calibration of the various components was carried out according to the rules presently in force. This proposal was applied, on an exploratory basis, to the data of a real site located in France. The authors present the preliminary results of some cyclic pressuremeter tests, previously carried out in the laboratory, on a sandy material, and they then provide a basic interpretation of these results. The findings indicated that the proposed apparatus is capable of providing high-quality information about constraints and deformations. Although these tests were performed within the laboratory, it was possible to analyze the power, quality, performance and insufficiencies of the proposed equipment.

• Asian Pacific Journal of Cancer Prevention
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• 제17권10호
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• pp.4665-4669
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• 2016

Purpose: To evaluate the legitimacy of a diagnosis of ASC-H in 5 cases which were followed up monthly for over 2 years with both cytology and HPV testing. Methods: Some 5 cases out of a total of 25.0 self-sampled Pap test patients diagnosed as ASC-H provided 119 specimens over 2 years, with HPV-DNA testing perormed using a E6 primer. Results: Cases 1, 2 and 3 showed SIL after the ASC-H diagnosis, while cases 4 and 5 showed and maintained NILM. Cases 1, 2 and 3 were further characterized by small atypical compressed binucleated cells, in which HPV was detected by in situ PCR. Case 4 showed a high N/C ratio in cells in sheets with a mild increase in chromatin. Case 5 demonstrated a high N/C ratio in small cells with no increase in chromatin. Conclusion: The finding of a compressed binucleated cells can define the difference between degenerated endocervical columnar cells and small atypical cells suggestive of HSIL. When small compressed binucleated squamous cells are detected, there may be a chance of continuing HPV infection and undetected SIL.

• 한국지반공학회지:지반
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• 제13권4호
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• pp.109-120
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• 1997

공용하중 상태에서 지반이 경험하는 변형률 크기는 0.1~1% 미만임이 밝혀지고 있다. 변형특성을 보다 엄밀히 평가하기 위하여는 미소변형률 영역에서의 신뢰성 있는 변형측정이 가능한 현장시험기기의 개발이 필요하다. 본 연구의 목적은 공내째하시험기(PMT)를 사용하여 지반의 미소변형률 전단탄성계수를 측정하는 것이다. 공내재하시험에서 시추공 설치에 따른 주위 지반의 교란효과를 제거하기 위하여 초기 하중재하단계가 아닌 역재하-재재하 단계에서 PMT 주위지 반의 응력상태 및 변형률 크기를 고려하여 미소변형률 잔단탄성계수를 결정하였다. 실내 토조에서 성형한 모래시료와 화강풍화토 현장지반에서 시험을 수행하였으며,시험결과로부터 본 연구 에서 사용한 PMT시험은 변형률 크기 10-2%~0.5% 범위에서 신뢰성 있는 전단탄성계수 측정이 가능하였다. 또한 변형률 크기를 고려하여 다른 실내외시험에서 결정된 전단탄성계수와 비교 하면 서로 잘일치하는 결과를 얻을 수 있었다.

• Geomechanics and Engineering
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• 제34권2호
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• pp.139-154
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• 2023

Red-bed soft rock is a common stratum and it is necessary to evaluate the mechanical properties and bearing capacity of red-bed soft rock mass affected by different environmental effects. This paper presents a complete procedure for evaluating the bearing capacity of red-bed soft rock by means of geophysical exploration and in-situ rock mechanics tests. Firstly, the thickness of surface loosened rock mass of red-bed soft rock was determined using geophysical prospecting method. Then, three environmental effects, including natural weathering effect, dry-wet cycling effect and concrete sealing effect, were considered. After each effect lasted for three months, in-situ rock mass mechanical tests were conducted. The test results show that the mechanical properties of rock mass considering the sealing effect of concrete were maintained. After considering the natural weathering effect, the mechanical parameters decrease to a certain extent. After considering the effect of dry-wet cycling, the decreases of mechanical parameters are the most significant. The test results confirm that the red-bed soft rock dam foundation rock mass will be significantly affected by various environmental effects. Therefore, combined with the mechanical test results, some useful implementations are proposed for the construction of a red-bed soft rock dam foundation.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2008년도 춘계 학술발표회 초청강연 및 논문집
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• pp.119-126
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• 2008

Ground stiffness(shear wave velocity) is one of the key parameters in geotechnical earthquake engineering. An In-situ seismic technique has its own advantages and disadvantages over the others in stiffness measurements. By combining the crosshole and seismic cone techniques and utilizing favourable features of bender elements, a new hybrid probe has been developed in order to enhance data quality and easiness of testing. The basic structure of the probe, called "MudFork", is a fork composed of two blades, on each of which source and receiver bender elements were mounted respectively. To evaluate the disturbance caused by the penetration of the probe, shear wave velocity measurements were carried out in the Kaolinite slurry in the laboratory. Finally, the probe was penetrated in coastal mud near Incheon, Korea, using SPT(standard penetration test)rods pushed with a routine boring machine and shear wave velocity measurements were carried out. The results were verified with data from laboratory and cone testing. The performance of the probe turns out to be excellent in terms of data quality and testing convenience.

• 한국도로학회논문집
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• 제11권2호
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• pp.85-98
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• 2009

현재, 포장시스템의 노상과 보조기층의 다짐관리는 들밀도 시험을 이용한 상대 다짐도와 평판재하시험이 널리 쓰이고 있다. 하지만, 이 두 시험법은 노상과 보조기층의 다짐관리를 평가하기엔 시간과 비용이 많이 소요되며 실측 값을 얻기에도 매우 어렵다. 이에 본 연구에서는 노상과 보조기층 시공 현장에서 다짐관리를 보다 빠르고, 적은 비용으로 측정 할 수 있는 소형충격재하시험들의 비교분석을 실시한 후, LFWD시험을 다짐평가장비로 제안하였다. 또한, 노상과 보조기층의 실내시험 및 현장 시험을 통하여 국내 도로 하부구조 재료 특성에 따른 $E_{LFWD}$와 상대 다짐도, $K_{30}$, 설계 $M_{R}$ 값과의 상관관계를 제안하였다.

• 한국지반공학회논문집
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• 제27권3호
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• pp.5-17
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• 2011

실내시험의 경우 샘플링으로 인한 시료의 교란은 종종 지반의 공학적 특성을 추정하는데 상당한 오차를 발생시키기 때문에 현장지반의 거동을 분석하는데 있어 부적절한 결과를 초래한다. 따라서 본 연구에서는 원위치시험법 중 하나인 스크류재하시험을 개발하였다. 그 이유는 신뢰성 있는 공학적 파라메터를 산정하기 위해서는 원위치시험법을 채택하는 것이 유리하기 때문이다. 스크류재하시험은 나선형의 오거 재하판을 지반 속에 관입하여 재하시험을 하는 평판 재하시험의 개량된 시험이다. 본 연구를 통해 스크류시험장치에 대한 구조와 특성을 자세히 소개하고 실내시험 결과를 통해 장치에 대한 신뢰성을 검증하였다.