• Composites Research
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• v.18 no.4
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• pp.1-7
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• 2005

In-situ structural health monitoring of filament wound pressure tanks were conducted during water-pressurizing test using embedded fiber Bragg grating (FBG) sensors. We need to monitor inner strains during working in order to verify the health condition of pressure tanks more accurately because finite element analyses on filament wound pressure tanks usually show large differences between inner and outer strains. Fiber optic sensors, especially FBG sensors can be easily embedded into the composite structures contrary to conventional electric strain gages (ESGs). In addition, many FBG sensors can be multiplexed in single optical fiber using wavelength division multiplexing (WDM) techniques. We fabricated a standard testing and evaluation bottle (STEB) with embedded FBG sensors and performed a water-pressurizing test. In order to increase the survivability of embedded FBG sensors, we suggested a revised fabrication process for embedding FBG sensors into a filament wound pressure tank, which includes a new protecting technique of sensor heads, the grating parts. From the experimental results, it was demonstrated that FBG sensors can be successfully adapted to filament wound pressure tanks for their structural health monitoring by embedding.

• Applied Chemistry for Engineering
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• v.26 no.1
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• pp.111-115
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• 2015

Two new analogs of bestatin were prepared from $\small{D}$-leucine and $\small{D}$-valine in a stereoselective and efficient way. An aminopeptidase inhibitor bestatin shows significant biological effects on immunomodulation and is marketed for the treatment of acute myelocytic leukemia. The key intermediates, trans-oxazolidine methyl esters 2a and 2b, were obtained with more than 20 to 1 stereoselectivity in a one-pot procedure by the three cascade reactions between N-hydroxymethyl protected ${\alpha}$-amino aldehydes (4a and 4b) and phenylsulfonylnitromethane ($PhSO_2CH_2NO_2$) and the following in-situ ozonolysis. Basic hydrolysis of 2a and 2b, and then the peptide coupling with $\small{L}$-Leu-OMe produced the protected derivatives of two new bestatin analogs, 3a and 3b, respectively. The new isobutyl and isopropyl analogs of bestatin (1a and 1b) were produced in overall 51% and 38% yields, respectively, with high stereoselectivity from the corresponding protected ${\alpha}$-amino aldehydes 4 in a six-step process.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.12
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• pp.7438-7442
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• 2014

An assessment of flocculation was performed by measuring the distribution of the floc size during sedimentation in water works. The size and number of flocs have a greater effect on an evaluation of the efficiency of flocculation rather than the turbidity. The data was collected in situ using particle image velocimetry and image analysis. The measurements were carried out at a water depth of 1m. The removal efficiency of the total organic compounds, UV absorbance and turbidity depended on the size and floc size distribution in flocculation as the G value. The G value of 50 sec-1, 30 sec-1 and 10 sec-1 showed the highest degree of efficiency in the case of an inlet water turbidity of 5 NTU, and the highest degree of efficiency was observed at a G value of 65 sec-1, 40 sec-1 and 10 sec-1 when the inlet water turbidity was 263 NTU. The number of flocs with a distribution of above $1,200{\mu}m$ was 14. The dynamics between two important growth mechanisms were investigated as the energy input changed. This is a certain method that makes use of the size and number of flocs as an efficiency assessment.

• Proceedings of the Polymer Society of Korea Conference
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• 2006.10a
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• pp.120-120
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• 2006

In our study grazing incidence X-ray scattering (GIXS) measurements with synchrotron radiation sources were conducted statically and in-situ for a series of nanoscale thin films prepared from nanoporous dielectrics, block copolymers, brush polymers, and molecular assemblies. All GIXS measurements were performed at the Pohang Accelerator Laboratory. The measured scattering data were analyzed in detail by using newly developed GIXS scattering theory. All GIXS results will be discussed in details with considering the materials chemistry and nanostructure formation process parameters.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.17
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• pp.7351-7355
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• 2014

Background: Laryngeal carcinogenesis is a multifactorial process that has not been fully elucidated. Despite extensive research, reliable markers with diagnostic and prognostic value are still lacking. It was recently reported that an elevated preoperative neutrophil-to-lymphocyte ratio (NLR) may correlate with an increased risk of recurrence, tumor aggressiveness and poorer prognosis in various malignancies. The aim of this study was to examine whether NLR could be used as an inflammatory marker to differentiate laryngeal squamous cell carcinoma (LSCC) patients from benign laryngeal lesion (BLL) and precancerous laryngeal lesion (PLL) patients. Materials and Methods: This retrospective study was performed on 209 patients admitted to a tertiary referral center with laryngeal lesions and undergoing biopsies to establish their histopathological diagnosis. We reviewed the patient files for their clinical, histopathological and laboratory data. The patients were divided into three groups according to their histopathological findings, as BLL, PLL and LSCC groups. The patients in the PLL group were also divided into three subgroups as mild, moderate and severe dysplasia/carcinoma in situ (CIS) subgroups. The groups were compared for NLR and the other laboratory data. Results: The mean NLRs of the BLL, PLL and the LSCC groups were $2.12{\pm}0.86$, $2.32{\pm}0.68$ and $3.46{\pm}1.51$, respectively, and the difference was statistically significant (p=0.001). The mean NLRs of the patients with PLL and LSCC were significantly higher than the patients with BLL (p=0.031 and p=0.001, respectively). The mean NLRs were similar among mild dysplasia, moderate dysplasia and severe dysplasia / CIS groups (p>0.05). Conclusions: To our knowledge, this is the first study investigating NLR in BLL, PLL and LSCC. NLR is an inexpensive, reproducible and widely available blood test, and could be a useful inflammatory marker to differentiate LSCC from BLL and PLL.

• Applied Chemistry for Engineering
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• v.19 no.4
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• pp.413-420
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• 2008

Over the past decade, there have been significant advancement in the field of electrospinning area. This study has focused on preparing yarn using polycarbonate (PC) nanofibers including modified multi-walled carbon nanotube (mMWNT) by solution electrospinning process using the mixture of solvents consisting of tretrahydronfuran (THF) and N,N-dimethylformamide (DMF). In order to enhance the dispersion, MWNT was chemically modified. TEM analysis for the prepared PC/mMWNT nanofibers reveals that mMWNT was well-dispersed into the PC nanofiber matrix. Also with increasing contents of mMWNT, thermal stability of PC/mMWNT nanofibers was improved than that of PC nanofibers. Moreover when 3 to 5 wt% of mMWNT was added, the nanofibers showed good electrical properties expecting antistatic effect, ranging 109.1~109.5 ${\Omega}$. It was confirmed that the multi-filament fibers using PC/mMWNT had $60{\sim}100{\mu}m$ in diameter and 4~5 cm in length.

• Journal of the Korea institute for structural maintenance and inspection
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• v.15 no.1
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• pp.198-208
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• 2011

When a structure which has relatively low load constructs on soft clay, the bearing capacity of the ground will be improved by sand overlying clay. In this condition, verifying the bearing capacity is difficult from the P.B.T etcetera in the in-situ. So, it is needed to estimate precise bearing capacity in the design process. In this study, 2-dimensional chamber tests and FEM analyses are conducted to evaluate behavior of bearing capacity for shallow foundations on a sand overlying clay. Because depth ratio H/B and bearing capacity ratio $q_c/q_s$ are selected as main factors, height of a sand, undrained shear strength of a clay and width of a loading are designated as variables. Results from chamber tests are very similar with those of FEM analyses. And it shows that punching shear mechanism is more suitable than the equation of Okamura et al.(1998). To make continual application of load spread mechanism, the equivalent load spread angle is proposed for H/B and $q_c/q_s$. Also, the linear regression equation of critical depth ratio Hf is suggested for $q_c/q_s$.

• Journal of the Microelectronics and Packaging Society
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• v.29 no.3
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• pp.37-42
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• 2022

Recently, the semiconductor package structures are becoming thinner and more complex. As the thickness decrease, interfacial delamination due to material mismatch can be further maximized, so the reliability of interface is a critical issue in industry field. Especially, the polymers, which are widely used in semiconductor packaging, are significantly affected by the temperature and moisture. Therefore, in this study, the delamination prediction at the interface of package structure was performed through finite element analysis considering the moisture absorption and desorption under the various temperature conditions. The material properties such as diffusivity and saturated moisture content were obtained from moisture absorption test. The hygro-swelling coefficients of each material were analyzed through TMA and TGA after the moisture absorption. The micro-shear test was conducted to evaluate the adhesion strength of each interface at various temperatures considering the moisture effect. The finite element analysis of interfacial delamination was performed that considers both deformation due to temperature and moisture absorption. Consequently, the interfacial delamination was successfully predicted in consideration of the in-situ moisture desorption and temperature behavior during the reflow process.

• Journal of the Korean Geotechnical Society
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• v.25 no.10
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• pp.17-30
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• 2009

Underground construction such as tunneling can induce damages on the surrounding rock mass, due to the stress concentration of in situ stresses and excessive energy input during construction sequence, such as blasting. The developed damage on the rock mass can have substantial influence on the mechanical and hydraulic behaviors of the rock masses around a tunnel. In this study, investigation on the generation of damage around an opening in a jointed rock model under biaxial compression condition was conducted. The joint dip angles employed are 30, 45, and 60 degrees to the horizontal, and the synthetic rock mass was made using early strength cement and water. From the biaxial compression test, initiation and propagation of tensile cracks at norm to the joint angle were found. The propagated tensile cracks eventually developed rock blocks, which were dislodged from the rock mass. Furthermore, the propagation process of the tensile cracks varies with joint angle: lower joint angle model shows more stable and progressive tensile crack propagation. The development of the tensile crack can be explained under the hypothesis that the rock segment encompassed by the joint set is subjected to the developing moment, which can be induced by the geometric irregularity around the opening in the rock model. The experiment results were simulated by using discrete element method PFC 2D. From the simulation, as has been observed from the test, a rock mass with lower joint angle produces wider damage region and rock block by tensile cracks. In addition, a rock model with lower joint angle shows progressive tensile cracks generation around the opening from the investigation of the interacted tensile cracks.

• Journal of the Korean Geotechnical Society
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• v.25 no.2
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• pp.55-66
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• 2009

At the mudstone slope located on the roadside of the Seokri area in Donghae-myeon, Pohang, Gyeongsangbuk-do, this study was performed to analyze the effects of rainfall on the stability of slope through seepage analysis according to the precipitation type of the mudstone slope, referring to the actual case of slope failure. For this, precise geological survey, geophysical exploration and drilling survey for the slope where the failure occurred were performed and followed by analysis of detailed soil layer. For the section where failure surface located, the durability reduction of rocks was measured through slaking/swelling tests and the permeability was measured through in-situ permeability tests for each soil layer. In addition, the change of strength parameter and process of instability were analyzed by back analysis, using Talren 97 and Slope/W programs, in the slope. By applying different precipitation conditions to the geographical conditions of the slope that had actual failure records, the slope stability was analyzed by seepage analysis according to duration of rainfall and rise of groundwater level resulting from the flow of rainfall caused by development of geological structures and the slope surface condition.