• 한국동물위생학회지
• /
• 제31권4호
• /
• pp.533-546
• /
• 2008

The efficacy of bovine immune sera to correct the calves with failure of passive transfer(FPT) was evaluated. Immune sera were produced from 14 one-year-old Holstein cattle which were inoculated commercial combined viral vaccine, administered by the challenge of some main enteric or respiratory viruses, aseptically filtered and stored at $4^{\circ}C$ before used. After the treatment of bovine immune sera, Mean transfer factor($mg/d{\ell}$, of IgG administered/kg of body weight) was $5.46{\pm}2.74,\;11.17{\pm}1.27,\;1.40{\pm}0.21$ in K-IP, H-IP and K-IV group, respectively. The corrective effect of bovine immune sera to FPT calf without any clinical signs showed that intravenous route was more effective than intraperitoneal administration(P<0.01). FPT calves with severe signs were not effective response to the immunotherapy used and consequently died within 10 days after the treatment. Ten percentage of controls appeared the clinical signs including diarrhea. On the contrary, there were not any clinical signs in K-IP and H-IV group. There was significant increase of the neutralizing titer against bovine viral diarrhea virus and bovine coronavirus as well as of cell population including CD2, CD4, and monocyte in K-IP and H-IV group after the immunotherapy(P<0.05). Also, K-IP and H-IV group showed the successful correction to FPT within one week after the immunotherapy, but controls had kept the FPT two-four weeks even after the same treatment. Consequently, the results were suggesting that the bovine immune sera could be used the corrective tool to young calves with FPT.

• 대한두경부종양학회:학술대회논문집
• /
• 대한두경부종양학회 1998년도 제3차 춘계심포지움
• /
• pp.115-117
• /
• 1998

• Clinical and Experimental Pediatrics
• /
• 제46권10호
• /
• pp.947-951
• /
• 2003

• 대한생식의학회:학술대회논문집
• /
• 대한불임학회 2001년도 제2차 연수강좌
• /
• pp.79-85
• /
• 2001

• 한국자기공명학회:학술대회논문집
• /
• 한국자기공명학회 2002년도 제20회 학술발표회
• /
• pp.8-8
• /
• 2002

• 한국미생물학회:학술대회논문집
• /
• 한국미생물학회 1998년도 제38회 춘계학술발표대회
• /
• pp.64-64
• /
• 1998

• 대한약학회:학술대회논문집
• /
• 대한약학회 2005년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
• /
• pp.221-221
• /
• 2005

• BMB Reports
• /
• 제54권1호
• /
• pp.1-1
• /
• 2021

• 한국버섯학회지
• /
• 제9권4호
• /
• pp.190-193
• /
• 2011

Inonotus obliquus is a traditional medicine mushroom that was developed from traditional medicine originating in ancient. It has been applied for cancer or immunotherapy, but its effect on pulmonary tuberculosis is not reported. Therefore, we measured the pulmonary tuberculosis therapeutic effect of methyl alcohol extract from MGIT 960 system with fluorescent indicator. Inonotus obliquus extract showed 14 day more inhibitory activity than the positive control. In addition, the anti-pulmonary tuberculosis activity of Inonotus obliquus was $50{\mu}m$. These results suggest that Inonotus obliquus methyl alcohol extracts could contribute to inhibition of pulmonary tuberculosis.

• Journal of Ginseng Research
• /
• 제32권1호
• /
• pp.67-72
• /
• 2008

for 4 h, tumoricidal activity was significantly increased. However, NSRG had effects on tumoricidal activity of macrophages at low concentration (1 ug/ml), which was not related to the production of nitric oxide. The mitogen response of lymphocytes to LPS and ConA in the spleen did not show significant differences between the control and NSRG-treated cells, whereas LPS-induced blastogenesis was slightly increased at 100 ${\mu}g/ml$ (p < 0.05). These results suggest that NSRG has differential effects on innate immune response and could be useful as immunotherapy for cancer treatment.