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http://dx.doi.org/10.5142/JGR.2008.32.1.067

Immunomodulatory Effects of Non-saponin Red Ginseng Components on Innate Immune Cells  

Sohn, Eun-Hwa (Department of Herbal Medicine Resource, Kangwon National University)
Kim, Ji-Hye (College of Pharmacy, Sungkyunkwan University)
Choi, Hye-Sook (College of Pharmacy, Sungkyunkwan University)
Park, Hye-Jin (College of Pharmacy, Sungkyunkwan University)
Kim, Byung-Oh (Department of Applied Biology, Kyungpook National University)
Rhee, Dong-Kwon (College of Pharmacy, Sungkyunkwan University)
Pyo, Suhk-Neung (College of Pharmacy, Sungkyunkwan University)
Publication Information
Journal of Ginseng Research / v.32, no.1, 2008 , pp. 67-72 More about this Journal
Abstract
for 4 h, tumoricidal activity was significantly increased. However, NSRG had effects on tumoricidal activity of macrophages at low concentration (1 ug/ml), which was not related to the production of nitric oxide. The mitogen response of lymphocytes to LPS and ConA in the spleen did not show significant differences between the control and NSRG-treated cells, whereas LPS-induced blastogenesis was slightly increased at 100 ${\mu}g/ml$ (p < 0.05). These results suggest that NSRG has differential effects on innate immune response and could be useful as immunotherapy for cancer treatment.
Keywords
non-saponin red ginseng; natural killer cells; tumoricidal activity; immunotherapy;
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Times Cited By KSCI : 3  (Citation Analysis)
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