• Journal of Internet Computing and Services
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• v.13 no.4
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• pp.45-52
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• 2012

T cells induce immune responses and thereby eliminate infected micro-organisms when peptides from the microbial proteins are bound to HLAs in the host cell surfaces, It is known that the more stable the binding of peptide to HLA is, the stronger the T cell response gets to remove more effectively the source of infection. Accordingly, if peptides (HLA binder) which can be bound stably to a certain HLA are found, those peptieds are utilized to the development of peptide vaccine to prevent infectious diseases or even to cancer. However, HLA is highly polymorphic so that HLA has a large number of alleles with some frequencies even in one population. Therefore, it is very inefficient to find the peptides stably bound to a number of HLAs by testing random possible peptides for all the various alleles frequent in the population. In order to solve this problem, computational methods have recently been developed to predict peptides which are stably bound to a certain HLA. These methods could markedly decrease the number of candidate peptides to be examined by biological experiments. Accordingly, this paper not only introduces a method of machine learning to predict peptides binding to an HLA, but also suggests a new prediction model so called 'knowledge-based genetic algorithm' that has never been tried for HLA binding peptide prediction. Although based on genetic algorithm (GA). it showed more enhanced performance than GA by incorporating expert knowledge in the process of the algorithm. Furthermore, it could extract rules predicting the binding peptide of the HLA alleles common in Koreans.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.15 no.4
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• pp.1317-1341
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• 2021

Nowadays, the Internet of Things (IoT) is adopted to enable effective and smooth communication among different networks. In some specific application, the Wireless Sensor Networks (WSN) are used in IoT to gather peculiar data without the interaction of human. The WSNs are self-organizing in nature, so it mostly prefer multi-hop data forwarding. Thus to achieve better communication, a cross-layer routing strategy is preferred. In the cross-layer routing strategy, the routing processed through three layers such as transport, data link, and physical layer. Even though effective communication achieved via a cross-layer routing strategy, energy is another constraint in WSN assisted IoT. Cluster-based communication is one of the most used strategies for effectively preserving energy in WSN routing. This paper proposes a Bio-inspired cross-layer routing (BiHCLR) protocol to achieve effective and energy preserving routing in WSN assisted IoT. Initially, the deployed sensor nodes are arranged in the form of a grid as per the grid-based routing strategy. Then to enable energy preservation in BiHCLR, the fuzzy logic approach is executed to select the Cluster Head (CH) for every cell of the grid. Then a hybrid bio-inspired algorithm is used to select the routing path. The hybrid algorithm combines moth search and Salp Swarm optimization techniques. The performance of the proposed BiHCLR is evaluated based on the Quality of Service (QoS) analysis in terms of Packet loss, error bit rate, transmission delay, lifetime of network, buffer occupancy and throughput. Then these performances are validated based on comparison with conventional routing strategies like Fuzzy-rule-based Energy Efficient Clustering and Immune-Inspired Routing (FEEC-IIR), Neuro-Fuzzy- Emperor Penguin Optimization (NF-EPO), Fuzzy Reinforcement Learning-based Data Gathering (FRLDG) and Hierarchical Energy Efficient Data gathering (HEED). Ultimately the performance of the proposed BiHCLR outperforms all other conventional techniques.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.42 no.4 s.334
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• pp.29-36
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• 2005

This paper presents the first hardware design of ARIA that KSA(Korea Standards Association) decided as the block encryption standard at Dec. 2004. The ARIA cryptographic algorithm has an efficient involution SPN (Substitution Permutation Network) and is immune to known attacks. The proposed ARIA design based on 1 cycle/round include a dual port ROM to reduce a size of circuit md a high speed round key generator with barrel rotator. ARIA design proposed is implemented with Xilinx VirtexE-1600 FPGA. Throughput is 437 Mbps using 1,491 slices and 16 RAM blocks. To demonstrate the ARIA system operation, we developed a security system cyphering video data of communication though Internet. ARIA addresses applications with high-throughput like data storage and internet security protocol (IPSec and TLS) as well as IC cards.

• Journal of Oral Medicine and Pain
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• v.44 no.4
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• pp.183-188
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• 2019

Erythema multiforme (EM) is an inflammatory immune-mediated mucosal disease. EM is classified as EM minor or EM major, depending on the severity of symptoms. Most patients with minor or major forms of EM have oral lesions. EM can occur as a result of adverse drug reactions but this is difficult to establish. Several indicators have been developed that can be used as a criterion of evaluation to ensure objectivity in identifying the causality of adverse drug reactions. The Naranjo algorithm was used in the evaluation to ensure objectivity in identifying the causality of adverse drug reactions. There were two cases of patients suspected of having EM induced by drugs. They were both assessed using the Naranjo algorithm to confirm the causality of the disease.

• Journal of the Korea Institute of Building Construction
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• v.23 no.4
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• pp.405-416
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• 2023

Recent seismic activities in countries like China and Turkey have underscored the widespread and severe damages that earthquakes can inflict globally. Being situated in a seismically active zone, South Korea can no longer regard itself as immune to earthquake hazards, necessitating the urgent adoption of proactive measures against such threats. The government has been proactive in evaluating, formulating processes, and methods for the seismic retrofitting of public buildings lacking in earthquake resistance. However, enforcement mechanisms for privately-owned apartment complexes are absent, and in the face of insufficient previous research and guidelines, preemptive measures for public safety remain alarmingly inadequate. With over 48% of residential structures in Korea aged over 30 years, and apartment complexes constituting more than 80% of these, the gravity of the situation is undeniable. This study deduces key factors for seismic retrofitting of apartment buildings like earthquake zones, soil type, building significance, aging degree, vulnerability, etc., based on building seismic design codes. It further proposes an algorithm for a more succinct and efficient determination of the priority of seismic reinforcements for apartment buildings.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.24 no.2
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• pp.86-91
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• 2010

We constructed a quasi-distributed fiber-optic sensor network for the safety monitoring in power systems. It is possible to construct many of FBG sensors in a line and to be immune from electromagnetic noise. For demodulation analysis of reflected wavelength from FBG sensor, we proposed a simple and fast system using a InGaAs photo-diode array and a holographic diffraction grating. For accuracy improvement of the proposed demodulation system, we applied a Gaussian line-fitting algorithm. We obtained about 4[pm] of wavelength resolution and stability.

• The Transactions of the Korean Institute of Electrical Engineers A
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• v.51 no.9
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• pp.441-450
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• 2002

In this paper, optimal tuning problem of power system stabilizer using IA-QFT is investigated to improve power system dynamic stability in spite of parameter variation and disturbance uncertainties. The most important feature of QFT is that it is able to deal with the design problem of complicated uncertain plants. However, loop shaping is currently performed in computer aided design environments manually and it is usually a trial and error procedure. It is difficult to design a controller to satisfy all specifications manually. To solve this problem, a study of design automation using IA needs to be taken into account. The robustness of the proposed controller has been investigated on a single machine infinite bus model. The results are shown that the proposed PSS using IA-QFT is more robust than conventional PSS.

• Proceedings of the Korean Institute of Intelligent Systems Conference
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• 2003.05a
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• pp.173-176
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• 2003

지문은 종생불변성, 만인부동성, 그리고 사용상의 편리함 때문에 신원인증을 위한 생체인식에 많이 사용되고 있다. 최근에는 기하학구조에 기반한 특이점 매칭방식이 제안되어 인식성능이 매우 높고 잡음에 강한 특성이 있으나 매칭 회수가 많아 인식속도가 느린 단점이 있다. 따라서 기존의 방식은 소수의 지문에 대한 1:다 매칭이나 1:1매칭에 주로 사용된다. 본 논문에서는 기존의 문제점들을 개선하기 위하여 생체 면역계의 자기-비자기 인식 능력에 주목하였다. 생체 면역계는 자기-비자기의 구별 능력을 바탕으로 바이러스나병원균 등의 낮선 외부침입자로부터 자신을 보호하고 침입자를 식별, 제거하는 시스템이다. 본 논문에서는 생체 면역계를 이루는 면역세포 중의 하나인 세포독성 T세포의 생성과정에서 자기, 비자기를 구별하기 위한 MHC 인식부를 형성하는 과정에 착안한 빠르고 신뢰성 있는 지문 인식 알고리즘을 제안한다. 제안한 방식은 지문에 존재하는 특이점(minutiae)인식을 통해 1단계로 global 패턴을 생성하고 2단계로 기하학적인 구조를 만들며, 인식시 global 패턴을 인식한 MHC 인식부에 대해서만 2차 local 매칭을 수행함으로써 매칭 속도가 매우 빠르며 지문의 비틀림이나 회전 등에 대하여 강인하게 인식된다.

• Journal of the Institute of Electronics Engineers of Korea SC
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• v.44 no.4 s.316
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• pp.74-78
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• 2007

Novel concept of sensor mat and its signal processing method is proposed for patient monitoring in medical application. Proposed sensor mat structure has sensing inner layer which has cross-linked arrangement using plastic optical fiber(POF). Large core diameter of plastic optical fiber behaved as band pass filter by averaging the noise component caused by unwanted environmental factors. Signal processor followed by sensor output added noise immune performance by filtering out unwanted component. Fail-proof patient breath monitoring scheme was realized by using intelligent decision algorithm. Unlike the conventional approach by using mechanical sensor, which have high sensitivity both to signal and to environmental noise, our approach provided reliable breath motion detection.

• Journal of Communications and Networks
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• v.13 no.5
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• pp.442-448
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• 2011

It's a challenging task to design a high performance modulation for satellite and space communications due to the limited power and bandwidth resource. Constant envelope modulation is an attractive scheme to be used in such cases for their needlessness of input power back-off about 2~3 dB for avoidance of nonlinear distortion induced by high power amplifier. The envelope of Feher quadrature phase shift keying (FQPSK) has a least fluctuation of 0.18 dB (quasi constant envelope) and can be further improved. This paper improves FQPSK by defining a set of new waveform functions, which changes FQPSK to be a strictly constant envelope modulation. The performance of the FQPSK adopting new waveform is justified by analysis and simulation. The study results show that the novel FQPSK is immune to the impact of HPA and outperforms conventional FQPSK on bit error rate (BER) performance. The BER performance of this novel modulation is better than that of FQPSK by more than 0.5 dB at least and 2 dB at most.