• Journal of the Korean Society for Industrial and Applied Mathematics
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• v.14 no.1
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• pp.35-42
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• 2010

A goal of Magnetic Resonance Imaging is reproducing a spatial map of the effective spin density from the measured Fourier coefficients of a specimen. The imaging procedure can be done by inverse Fourier transformation or backward fast Fourier transformation if the data are sampled on a regular grid in frequency space; however, it is still a challenging question how to reconstruct an image from a finite set of Fourier data on irregular points in k-space. In this paper, we describe some mathematical and numerical properties of imaging techniques from non-uniform MR data using the pseudo-inverse or the diagonal-inverse weight matrix. This note is written as an easy guide to readers interested in the non-uniform MRI techniques and it basically follows the ideas given in the paper by Greengard-Lee-Inati [10, 11].

• Radiation Oncology Journal
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• v.35 no.2
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• pp.101-111
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• 2017

The number of imaging data sets has significantly increased during radiation treatment after introducing a diverse range of advanced techniques into the field of radiation oncology. As a consequence, there have been many studies proposing meaningful applications of imaging data set use. These applications commonly require a method to align the data sets at a reference. Deformable image registration (DIR) is a process which satisfies this requirement by locally registering image data sets into a reference image set. DIR identifies the spatial correspondence in order to minimize the differences between two or among multiple sets of images. This article describes clinical applications, validation, and algorithms of DIR techniques. Applications of DIR in radiation treatment include dose accumulation, mathematical modeling, automatic segmentation, and functional imaging. Validation methods discussed are based on anatomical landmarks, physical phantoms, digital phantoms, and per application purpose. DIR algorithms are also briefly reviewed with respect to two algorithmic components: similarity index and deformation models.

• Molecules and Cells
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• v.26 no.6
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• pp.530-535
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• 2008

Optical signals based on Raman scattering, coherent anti-Stokes Raman scattering (CARS), and harmonic generation can be used to image biological molecules in living cells without labeling. Both Raman scattering and CARS signals can be used to detect frequencies of molecular vibrations and to obtain the molecular distributions in samples. Second-harmonic optical signals can also be generated in structured arrays of noncentrosymmetric molecules and can be used to detect structured aggregates of proteins, such as, collagen, myosin and tubulin. Since labeling techniques using chemical and biological reactions may cause undesirable changes in the sample, label-free molecular imaging techniques are essential for observation of living samples.

• Mass Spectrometry Letters
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• v.11 no.3
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• pp.41-51
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• 2020

Microbes influence many aspects of human life from the environment to health, yet evaluating their biological processes at the chemical level can be problematic. Mass spectrometry imaging (MSI) enables direct evaluation of microbial chemical processes at the atomic to molecular levels without destruction of valuable two-dimensional information. MSI is a label-free method that allows multiplex spatiotemporal visualization of atomic- or molecular-level information of microbial and microberelated samples. As a result, microbial MSI has become an important field for both mass spectrometrists and microbiologists. In this review, basic techniques for microbial MSI, such as ionization methods and analyzers, are explored. In addition, we discuss practical applications of microbial MSI and various data-processing techniques.

• Nuclear Medicine and Molecular Imaging
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• v.41 no.2
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• pp.71-77
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• 2007

Advance of neuroimaging technique has greatly influenced recent brain research field. Among various neuroimaging modalities, positron emission tomography has played a key role in molecular neuroimaging though functional MRI has taken over its role in the cognitive neuroscience. As the analysis technique for PET data is more sophisticated, the complexity of the method is more increasing. Despite the wide usage of the neuroimaging techniques, the assumption and limitation of procedures have not often been dealt with for the clinician and researchers, which might be critical for reliability and interpretation of the results. In the current paper, steps of voxel-based statistical analysis of PET including preprocessing, intensity normalization, spatial normalization, and partial volume correction will be revisited in terms of the principles and limitations. Additionally, new image analysis techniques such as surface-based PET analysis, correlational analysis and multimodal imaging by combining PET and DTI, PET and TMS or EEG will also be discussed.

• 제어로봇시스템학회:학술대회논문집
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• 2001.10a
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• pp.28.2-28
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• 2001

Three dimensional shape measurement techniques are widely needed in industries for product quality monitoring and control. X-ray imaging method is a promising technology to achieve three-dimensional Information, both the surface and inner structure of an object, since it can overcome the limitations of conventional visual or optical methods such as an occlusion problem or surface reflection properties. In this paper, we propose three dimensional volume reconstruction method based on x-ray stereo imaging technology. Here, the stereo images of an object from two different views are taken by changing the object pose rather than moving imaging plane as in conventional stereo vision method. We propose a series of image processing techniques to extract the features efficiently from x-ray images, where the occluded features in case of normal camera vision could be found ...

• Korean Journal of Radiology
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• v.22 no.11
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• pp.1749-1763
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• 2021

Coronary computed tomography angiography (CCTA) is routinely used for anatomical assessment of coronary artery disease (CAD). However, invasive measurement of fractional flow reserve (FFR) is the current gold standard for the diagnosis of hemodynamically significant CAD. CT-derived FFRCT and CT perfusion are two emerging techniques that can provide a functional assessment of CAD for risk stratification and clinical decision making. Several clinical studies have shown that the diagnostic performance of concomitant CCTA and functional CT assessment for detecting hemodynamically significant CAD is at least non-inferior to that of other routinely used imaging modalities. This article aims to review the current clinical evidence and recent developments in functional CT techniques.

• Journal of the Korean Society of Radiology
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• v.81 no.1
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• pp.70-80
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• 2020

Currently, there has been an increase in the use of surgical modalities to treat lymphedema and MR imaging to examine lymphatic vessels. Furthermore, there have been several advancements in the field of MR imaging, from the traditional heavily T2-weighted images to three-dimensional images. Three-dimensional images include spoiled gradient echo images, and numerous advanced techniques have been implemented. Among the fat suppression techniques, mDixon technique has recently been in the spotlight.

• Journal of Biosystems Engineering
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• v.28 no.3
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• pp.253-260
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• 2003

In this study, the feasibility of magnetic resonance techniques for nondestructive internal quality evaluation of Korean red ginseng was examined. Relaxation time constants were measured using various grades of red ginsengs. Solid state magnetic resonance imaging technique was applied to image dried red ginsengs which have low moisture contents (about 13%). A 7 tesla magnetic resonance imaging system operating at a proton resonant frequency of 300 ㎒ was used for acquiring MR images of dried Korean red ginseng. The comparison test of cross cut digital images and magnetic resonance images of heaven grade, good grade with cavity inside, and good grade with white part inside red ginseng suggested the feasibility of the internal quality evaluation of Korean red ginsengs using MRI techniques. A good grade red ginseng included abnormal tissues such as cavities or white parts inside was observed by the signal intensity of MR image based on magnetic resonance properties of proton nucleus. Analysis on an one dimensional profile of acquired MR image of Korean red ginseng showed easy discrimination of normal and abnormal tissues. MR techniques suggested ways to detect internal defects of red ginsengs effectively.

• Journal of Magnetics
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• v.21 no.4
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• pp.593-598
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• 2016

In order to reduce the amount of noise component in X-ray imaging system, various reduction techniques were frequently used in the field of diagnostic imaging. Although the previous techniques -such as median, Wiener filters and Anscombe noise reduction technique - were able to reduce the noise, the edge information was still damaged. In order to cope with this problem, total variation (TV) noise reduction technique has been developed and researched. The purpose of this study was to evaluate and compare the image quality using normalized noise power spectrum (NNPS) and contrast-to-noise ratio (CNR) through simulations and experiments with respect to the above-mentioned noise reduction techniques. As a result, not only lowest NNPS value but also highest CNR values were acquired using a TV noise reduction technique. In conclusion, the results demonstrated that TV noise reduction technique is proved as the most practical method to ensure accurate denoising in X-ray imaging system.