• Nuclear Medicine and Molecular Imaging
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• v.41 no.2
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• pp.152-157
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• 2007

Imaging of the dopamine transporter (DAT) provides a marker for the integrity of presynaptic nigrostriatal dopaminergic system. DAT density is reduced in Parkinson disease, multiple system atrophy, and progressive supranuclear palsy. In patients with suspicious parkinsonism, normal DAT imaging suggests an alternative diagnosis such as essential tremor, vascular parkinsonism, or drug-induced parkinsonism. DAT imaging is a useful tool to aid clinician's differential diagnosis in parkinsonism.

• Parasites, Hosts and Diseases
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• v.45 no.2 s.142
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• pp.77-85
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• 2007

Among several diagnostic tools for clonorchiasis (Clonorchis sinensis infection), radiologic examinations are commonly used in clinical practices. During the 2 past decades, many reports regarding imaging findings of clonorchiasis were introduced. The basic imaging finding of clonorchiasis is diffuse dilatation of the peripheral intra-hepatic bile ducts, without dilation of the large intrahepatic or extrahepatic bile ducts. By this finding, however, active clonorchiasis cannot be differentiated from cured infection. Some recent radiologic studies suggested specific findings of active clonorchiasis. Besides direct demonstration of worms, increased periductal echogenicity on sonography and periductal enhancement on dynamic contrast-enhanced CT or MR imaging possibly represent active clonorchiasis. Those images of the liver clonorchiasis are known to be correlated with worm burdens (EPG counts) in their frequency and also severity. The images of cholangiocarcinoma associated with clonorchiasis show both the tumor with obstruction images and diffuse dilatation of the peripheral intrahepatic bile ducts. Radiological images can be a good practical alternative diagnostic method of clonorchiasis.

• Journal of Biomedical Engineering Research
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• v.42 no.5
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• pp.241-249
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• 2021

Recently, artificial intelligence for diagnosis system of obstetric diseases have been actively studied. Artificial intelligence diagnostic assist systems, which support medical diagnosis benefits of efficiency and accuracy, may experience problems of poor learning accuracy and reliability when inappropriate images are the model's input data. For this reason, before learning, We proposed an algorithm to exclude unread cervical imaging. 2,000 images of read cervical imaging and 257 images of unread cervical imaging were used for this study. Experiments were conducted based on the statistical method Radiomics to extract feature values of the entire images for classification of unread images from the entire images and to obtain a range of read threshold values. The degree to which brightness, blur, and cervical regions were photographed adequately in the image was determined as classification indicators. We compared the classification performance by learning read cervical imaging classified by the algorithm proposed in this paper and unread cervical imaging for deep learning classification model. We evaluate the classification accuracy for unread Cervical imaging of the algorithm by comparing the performance. Images for the algorithm showed higher accuracy of 91.6% on average. It is expected that the algorithm proposed in this paper will improve reliability by effectively excluding unread cervical imaging and ultimately reducing errors in artificial intelligence diagnosis.

• Journal of Cardiovascular Imaging
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• v.31 no.4
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• pp.159-168
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• 2023

BACKGROUND: The gold standard for diagnosis of cardiac tumours is histopathological examination. Cardiovascular magnetic resonance (CMR) is a valuable non-invasive, radiation-free tool for identifying and characterizing cardiac tumours. Our aim is to understand CMR diagnosis of cardiac tumours by distinguishing benign vs. malignant tumours compared to the gold standard. METHODS: A systematic search was performed in the PubMed, Web of Science, and Scopus databases up to December 2022, and the results were reviewed by 2 independent investigators. Studies reporting CMR diagnosis were included in a meta-analysis, and pooled measures were obtained. The risk of bias was assessed using the Quality Assessment Tools from the National Institutes of Health. RESULTS: A total of 2,321 results was obtained; 10 studies were eligible, including one identified by citation search. Eight studies were included in the meta-analysis, which presented a pooled sensitivity of 93% and specificity of 94%, a diagnostic odds ratio of 185, and an area under the curve of 0.98 for CMR diagnosis of benign vs. malignant tumours. Additionally, 4 studies evaluated whether CMR diagnosis of cardiac tumours matched specific histopathological subtypes, with 73.6% achieving the correct diagnosis. CONCLUSIONS: To the best of our knowledge, this is the first published systematic review on CMR diagnosis of cardiac tumours. Compared to histopathological results, the ability to discriminate benign from malignant tumours was good but not outstanding. However, significant heterogeneity may have had an impact on our findings.

• Parasites, Hosts and Diseases
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• v.47 no.1
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• pp.53-56
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• 2009

The authors report here a rare case of cerebellar schistosomiasis identified by pathological diagnosis, lacking extracranial involvement. The clinical symptoms included headache, dizziness, and nausea. Studies in blood were normal and no parasite eggs were detected in stool. Computed tomography of brains showed hypodense signal, and magnetic resonance imaging showed isointense signal on T1-weighted images, hyperintense signal on T2-weighted images, and intensely enhancing nodules in the right cerebellum after intravenous administration of gadolinium. A high-grade glioma was suspected, and an operation was performed. The pathologic examination of the biopsy specimen revealed schistosomal granulomas scattered within the parenchyma of the cerebellum. The definitive diagnosis was cerebellar schistosomiasis japonica. A standard use of praziquantel and corticosteroid drugs was applied, and the prognosis was good. When the pattern of imaging examinations is present as mentioned above, a diagnosis of brain schistosomiasis should be considered.

• Mass Spectrometry Letters
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• v.10 no.3
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• pp.71-78
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• 2019

For several decades, cancer has been the primary cause of mortality worldwide. New diagnosis and regimens have been developed to improve the chemotherapeutic efficacy and the quality of life of the patients. However, cancer tissues are complex and difficult to assess. Understanding the various properties of the tumor and its environment is crucial for cancer and pharmaceutical research. Several analytical techniques have been providing new insights into cancer research. Recently, matrix-assisted laser desorption ionization (MALDI)-mass spectrometry imaging (MSI), an advanced analytical technique, has been applied to translational research. Proteomic and lipidomic profiling obtained by MALDI-MSI has been critical for biomarker discovery and for monitoring heterogenous tumor tissues. In this review, we discuss technical approaches, benefits and recent applications of MALDI-MSI as a valuable tool in cancer research, namely for diagnosis, therapy, prognosis.

• The Journal of the Korean dental association
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• v.50 no.4
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• pp.189-195
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• 2012

Various imaging modalities have been used for dental implant assessment in the different stages of implant treatment. Basic imaging, such as panoramic and periapical radiographs, are generally useful and cost-effective but do not provide the cross-sectional visualization or interactive image analysis that can be obtained with more sophisticated imaging techniques, such as Cone-Beam Computed Tomography(CBCT) imaging. This article includes the applications of CBCT imaging and their diagnostic contribution to presurgical evaluation, treatment planning, and postoperative assessment of dental implants.

• Nuclear Medicine and Molecular Imaging
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• v.42 no.6
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• pp.425-434
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• 2008

Dopamine transporter imaging is useful in the diagnosis of Parkinson's disease and the most successful technique in the clinical use of neuroreceptor imaging. Recently, several radiopharmaceuticals including I-123 FP-CIT, Tc-99m TRODAT, and F-18 FP-CIT for dopamine transporter imaging have been approved for the routine clinical use in several European countries, Taiwan and Korea, respectively. This review summarized the practical issue for the routine clinical examination of dopamine transporter imaging.

• Proceedings of the Korean Society of Veterinary Clinics Conference
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• 2008.10a
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• pp.191-191
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• 2008

• Imaging Science in Dentistry
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• v.51 no.3
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• pp.307-311
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• 2021

Purpose: An oroantral communication (OAC) is an abnormal space between the maxillary sinus and oral cavity. The causes, complications, treatment, and radiographic features of OAC in 2-dimensional and 3-dimensional imaging modalities are discussed. Materials and Methods: This pictorial review presents a broad spectrum of imaging findings of OAC. Representative radiographs depicting OAC were chosen from our database. PubMed was used to conduct a comprehensive literature search of OAC. Results: Characteristic features of OAC include discontinuity of the maxillary sinus floor, thickening of the maxillary sinus mucosa, or a combination of both. Two-dimensional imaging modalities are the method of choice for identifying discontinuities in the maxillary sinus floor. However, 3-dimensional imaging modalities are also essential for determining the status of soft tissue in the maxillary sinus. Conclusion: The integration of 2-dimensional and 3-dimensional imaging modalities is crucial for the correct diagnosis and comprehensive treatment of OAC. However, the diagnosis of OAC must be confirmed clinically to prevent unnecessary mental and financial burdens to patients.