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http://dx.doi.org/10.3347/kjp.2009.47.1.53

Cerebellar Schistosomiasis: A Case Report with Clinical Analysis  

Wan, Heng (Department of Neurology and Functional Neurosurgery, West China Fourth Hospital of Sichuan University)
Lei, Ding (Department of Neurosurgery, West China Hospital of Sichuan University)
Mao, Qing (Department of Neurology, Huashan Hospital of Fudan University)
Publication Information
Parasites, Hosts and Diseases / v.47, no.1, 2009 , pp. 53-56 More about this Journal
Abstract
The authors report here a rare case of cerebellar schistosomiasis identified by pathological diagnosis, lacking extracranial involvement. The clinical symptoms included headache, dizziness, and nausea. Studies in blood were normal and no parasite eggs were detected in stool. Computed tomography of brains showed hypodense signal, and magnetic resonance imaging showed isointense signal on T1-weighted images, hyperintense signal on T2-weighted images, and intensely enhancing nodules in the right cerebellum after intravenous administration of gadolinium. A high-grade glioma was suspected, and an operation was performed. The pathologic examination of the biopsy specimen revealed schistosomal granulomas scattered within the parenchyma of the cerebellum. The definitive diagnosis was cerebellar schistosomiasis japonica. A standard use of praziquantel and corticosteroid drugs was applied, and the prognosis was good. When the pattern of imaging examinations is present as mentioned above, a diagnosis of brain schistosomiasis should be considered.
Keywords
Schistosoma japonicum; schistosomiasis; brain; computed tomography; magnetic resonance imaging;
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