• The Microorganisms and Industry
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• v.26 no.1
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• pp.8-17
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• 2000

Thirtythree strains of the Aspergillus spp. isolated from foodstuffs were observed through some physiological characteristics for detection of identification key of Aspergillus spp. 1) Each strain of Aspergillus spp. had their specific characteristics and could be used for identification of species. 2) Excellent amylase-producing fungi were observed among the isolated strains of Aspergillus spp. 3) Amylase activities increased for one week incubation period. 4) In the tests of common characters of aflatoxin-producing fungi among the 33 strains of Aspergillus spp., for example, conidial size, presence of sclerotia, kojic acid, and pigment production, coloration of phenol, reduction of methylene blue, etc.

• Mycobiology
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• v.42 no.4
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• pp.405-408
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• 2014

Leaf spot disease was observed in sesame (Sesamum indicum L.) during 2009 and 2010 in Korea. The pathogen was identified as Alternaria simsimi based on morphological and cultural characteristics. The morphological identification was well supported by phylogenetic analysis of the ribosomal DNA-internal transcribed spacer region. A. simsimi isolates caused spot symptoms on leaves and stems of sesame plants 2 wk after artificial inoculation, which were similar to those observed in the field. This is the first record of leaf spot disease in Korea caused by A. simsimi.

• Clinical and Experimental Pediatrics
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• v.56 no.2
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• pp.52-59
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• 2013

Cardiomyopathy (CMP) is a heterogeneous disease caused by a functional abnormality of the cardiac muscle. CMP is of 2 major types, dilated and hypertrophic, and is further classified as either primary or secondary. Secondary CMP is caused by extrinsic factors, including infection, ischemia, hypertension, and metabolic disorders. Primary CMP is diagnosed when the extrinsic factors of secondary CMP are absent. Furthermore, the World Health Organization, American Heart Association, and European Cardiology Association have different systems for clinically classifying primary CMP. Primary CMP is rare and associated with a family history of the disease, implying that genetic factors might affect its incidence. In addition, the incidence of CMP varies widely according to patient ethnicity. Genetic testing plays an important role in the care of patients with CMP and their families because it confirms diagnosis, determines the appropriate care for the patient, and possibly affects patient prognosis. The diagnosis and genetic identification of CMP in patients' families allow the possibility to identify novel genes that may lead to new treatments. This review focuses on the epidemiology, pathophysiology, diagnosis, and treatment of CMP, with the aim of providing pediatricians with insights that may be helpful in the early identification and management of idiopathic CMP in children.

• 대한상한금궤의학회지
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• v.12 no.1
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• pp.137-147
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• 2020

Objective: In this study, we aimed to inform people that acne can be improved with Osuyu-tang (OSYT) based on the Shanghanlun disease pattern identification diagnostic system (DPIDS). Methods: We evaluated the progress of symptoms, patient compliance, and presence of side effects after the patient took OSYT. The progress of acne treatment was evaluated using the Korean Acne Grading System (KAGS), visual findings, and patient statements. Results: According to the DPIDS, the patient was diagnosed with provision 309 of soyinbing. After administration of OSYTfor 50 days, KAGS decreased from grade 3 to grade 1. Cold hands and feet improved significantly. Conclusions: Through this case study, we showed the possibility of the clinical interpretation and application of OSYT and suggested further case studies in the future.

• 대한상한금궤의학회지
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• v.9 no.1
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• pp.37-45
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• 2017

Objective : The purpose of this paper is to report the improvement of patient with pitting edema treated by herb medication based on Shanghanlun disease pattern identification diagnostic system. Methods : According to 'Disease Pattern Identification Diagnostic System based on Shanghanlun Provisions', the patient was diagnosed with Taeyang-byung, number 96 provision, and took Soshiho-tang herb medication 30days. The changing symptom of pitting edema is reported depended on the edema scale and the statement of patient during treatment. Results : The pitting edema of patient disappeared by 96 provision of Soshiho-tang seclected according to Shanghanlun provisions. Conclusions : This case report suggests that two words on the 96 provision of Shanghanlun, '或 心下悸, 小便不利'(palpitations below the heart, inhibited urination) indcate close relationship between palpitation and decrease of genital secretions, which affected the edema in this case.

• 대한상한금궤의학회지
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• v.12 no.1
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• pp.199-209
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• 2020

Objective: The purpose of this paper is to report the improvement in a patient with benign paroxysmal positional vertigo (BPPV) treated with herbal medication based on the Shanghanlun disease pattern identification diagnostic system. Methods: According to the 'Disease Pattern Identification Diagnostic System based on Shanghanlun Provisions,'the patient was diagnosed with Guorem-byung number 350 provision, and took Baekho-tang herbal medication for 15 days. The result of administration was evaluated using the Dizziness Handicap Inventory (DHI) and the Visual Analog Scale (VAS). Results: After administration of Baekho-tang for 15 days, based on the 350 provision of Baekho-tang diagnosed according to the Shanghanlun provisions, the DHI score decreased from 74 to 16 and the VAS score decreased from 10 to 1. Conclusions: The patient recovered from symptoms of BPPV. This case report suggests that the words '滑,''厥,''裏'on the 350 provision of Shanghanlun mean physical and psychological causes of BPPV in this case.

• Mycobiology
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• v.50 no.5
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• pp.382-388
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• 2022

White mold (or Sclerotinia stem rot), caused by Sclerotinia species, is a major air, soil, or seed-transmitted disease affecting numerous crops and wild plants. Microscopic or culture-based methods currently available for their detection and identification are time-consuming, laborious, and often erroneous. Therefore, we developed a multiplex quantitative PCR (qPCR) assay for the discrimination, detection, and quantification of DNA collected from each of the three economically relevant Sclerotinia species, namely, S. sclerotiorum, S. minor, and S. nivalis. TaqMan primer/probe combinations specific for each Sclerotinia species were designed based on the gene sequences encoding aspartyl protease. High specificity and sensitivity of each probe were confirmed for sclerotium and soil samples, as well as pure cultures, using simplex and multiplex qPCRs. This multiplex assay could be helpful in detecting and quantifying specific species of Sclerotinia, and therefore, may be valuable for disease diagnosis, forecasting, and management.

• 대한상한금궤의학회지
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• v.11 no.1
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• pp.27-34
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• 2019

Objective : The purpose of the present study was to report the improvement of functional abdominal pain in a patient treated with a herb medication based on a disease pattern identification diagnostic system under the provision of Shanghanlun (DPIDS). Methods : According to DPIDS, the patient was diagnosed with Taeyang-byung, no. 25 provision, and was administered with Gyejiyimahwangyil-tang herb medication for 60 days. The severity of the abdominal pain was assessed with the five-point Likert scale. Results : The abdominal pain in the patient disappeared following treatment with Gyejiyimahwangyil-tang, which is described in the 25th provision of Shanghanlun. Conclusions : The present case report suggests that '瘧', a word in the 25th provision of Shanghanlun may indicate severe abdominal pain at nighttime and not just malaria.

• 대한상한금궤의학회지
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• v.13 no.1
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• pp.61-79
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• 2021

Objective : The objective of this study was to explore the meaning of "man (滿)" in Shanghanlun through the analysis of four cases. Methods : We analyzed four cases treated with modified Soshiho-tang, which is administered when 滿 aggravates chief complaints. All cases were diagnosed by the disease pattern identification diagnostic system based on the Shanghanlun provisions. Results : All 4 patients' chief complaints were improved after administration of modified Soshiho-tang. Swelling symptoms were reduced in all 4 cases. Through the etymological research and clinical treatment results, the clinical meaning of 滿 was deduced as "swelling." Conclusions : The etymological and clinical analysis suggest that the concept of "滿" may be defined as "swelling" in the Shanghanlun provisions.

• Journal of Animal Science and Technology
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• v.57 no.11
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• pp.32.1-32.8
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• 2015

Peste des petits ruminants (PPR) is considered to be one of the main constraints to enhancing the productivity of goats and sheep in regions where it is present and becoming endemic. PPR was recognized in Pakistan in early 1990s but got importance during the Participatory Disease Surveillance (PDS) of Rinderpest Eradication Campaign. Lot of research work has been initiated during last decade towards disease epidemiology, risk factor recognition, laboratory diagnosis, vaccination and demonstration of control strategies. Although there are ongoing projects working towards the progressive control of the disease in country yet there is need to have a national level control program for PPR. Also there is need to have comprehensive social economic surveys, disease hot spot recognition and identification of role of other species in disease transmission. With combined efforts of local and national authorities and political will, there is high likelihood that this devastating disease can be controlled and eventually eradicated in near future.